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Items: 1 to 50 of 111

1.

Hox gene cluster of the ascidian, Halocynthia roretzi, reveals multiple ancient steps of cluster disintegration during ascidian evolution.

Sekigami Y, Kobayashi T, Omi A, Nishitsuji K, Ikuta T, Fujiyama A, Satoh N, Saiga H.

Zoological Lett. 2017 Sep 15;3:17. doi: 10.1186/s40851-017-0078-3. eCollection 2017.

2.

Transcriptional regulation of a horizontally transferred gene from bacterium to chordate.

Sasakura Y, Ogura Y, Treen N, Yokomori R, Park SJ, Nakai K, Saiga H, Sakuma T, Yamamoto T, Fujiwara S, Yoshida K.

Proc Biol Sci. 2016 Dec 28;283(1845). pii: 20161712. doi: 10.1098/rspb.2016.1712.

3.

Syndecans promote mycobacterial internalization by lung epithelial cells.

Zimmermann N, Saiga H, Houthuys E, Moura-Alves P, Koehler A, Bandermann S, Dorhoi A, Kaufmann SH.

Cell Microbiol. 2016 Dec;18(12):1846-1856. doi: 10.1111/cmi.12627. Epub 2016 Jul 15.

PMID:
27279134
4.

Polarization of PI3K Activity Initiated by Ooplasmic Segregation Guides Nuclear Migration in the Mesendoderm.

Takatori N, Oonuma K, Nishida H, Saiga H.

Dev Cell. 2015 Nov 9;35(3):333-43. doi: 10.1016/j.devcel.2015.10.012.

5.

Hox10-regulated endodermal cell migration is essential for development of the ascidian intestine.

Kawai N, Ogura Y, Ikuta T, Saiga H, Hamada M, Sakuma T, Yamamoto T, Satoh N, Sasakura Y.

Dev Biol. 2015 Jul 1;403(1):43-56. doi: 10.1016/j.ydbio.2015.03.018. Epub 2015 Apr 14.

6.

The Recombinant BCG ΔureC::hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation.

Saiga H, Nieuwenhuizen N, Gengenbacher M, Koehler AB, Schuerer S, Moura-Alves P, Wagner I, Mollenkopf HJ, Dorhoi A, Kaufmann SH.

J Infect Dis. 2015 Jun 1;211(11):1831-41. doi: 10.1093/infdis/jiu675. Epub 2014 Dec 11.

PMID:
25505299
7.

Analysis of the Transcription Regulatory Mechanism of Otx During the Development of the Sensory Vesicle in Ciona intestinalis.

Oonuma K, Hirose D, Takatori N, Saiga H.

Zoolog Sci. 2014 Sep;31(9):565-72. doi: 10.2108/zs140060.

PMID:
25186927
8.

Continuous expression of Otx in the anterior neural lineage is supported by different transcriptional regulatory mechanisms during the development of Halocynthia roretzi.

Oonuma K, Hirose D, Takatori N, Saiga H.

Dev Growth Differ. 2014 Feb;56(2):189-98. doi: 10.1111/dgd.12118. Epub 2014 Jan 17.

PMID:
24433293
9.

Giant vascular eccrine spiradenoma mimicking calcifying epithelioma.

Hatano A, Kobayashi T, Fukuzumi S, Shirakashi Y, Nishimura C, Gomi H, Saiga H, Hayakawa K.

J Dermatol. 2013 Oct;40(10):853-4. doi: 10.1111/1346-8138.12254. Epub 2013 Aug 21. No abstract available.

PMID:
23961898
10.

Ifit1 inhibits Japanese encephalitis virus replication through binding to 5' capped 2'-O unmethylated RNA.

Kimura T, Katoh H, Kayama H, Saiga H, Okuyama M, Okamoto T, Umemoto E, Matsuura Y, Yamamoto M, Takeda K.

J Virol. 2013 Sep;87(18):9997-10003. doi: 10.1128/JVI.00883-13. Epub 2013 Jul 3.

11.

Formation of the digestive tract in Ciona intestinalis includes two distinct morphogenic processes between its anterior and posterior parts.

Nakazawa K, Yamazawa T, Moriyama Y, Ogura Y, Kawai N, Sasakura Y, Saiga H.

Dev Dyn. 2013 Oct;242(10):1172-83. doi: 10.1002/dvdy.24009. Epub 2013 Jul 29.

12.

Identification of an intact ParaHox cluster with temporal colinearity but altered spatial colinearity in the hemichordate Ptychodera flava.

Ikuta T, Chen YC, Annunziata R, Ting HC, Tung CH, Koyanagi R, Tagawa K, Humphreys T, Fujiyama A, Saiga H, Satoh N, Yu JK, Arnone MI, Su YH.

BMC Evol Biol. 2013 Jun 27;13:129. doi: 10.1186/1471-2148-13-129.

13.

CREBH determines the severity of sulpyrine-induced fatal shock.

Kamiyama N, Yamamoto M, Saiga H, Ma JS, Ohshima J, Machimura S, Sasai M, Kimura T, Ueda Y, Kayama H, Takeda K.

PLoS One. 2013;8(2):e55800. doi: 10.1371/journal.pone.0055800. Epub 2013 Feb 7.

14.

Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine.

Kusu T, Kayama H, Kinoshita M, Jeon SG, Ueda Y, Goto Y, Okumura R, Saiga H, Kurakawa T, Ikeda K, Maeda Y, Nishimura J, Arima Y, Atarashi K, Honda K, Murakami M, Kunisawa J, Kiyono H, Okumura M, Yamamoto M, Takeda K.

J Immunol. 2013 Jan 15;190(2):774-83. doi: 10.4049/jimmunol.1103067. Epub 2012 Dec 14.

15.

Identical genomic organization of two hemichordate hox clusters.

Freeman R, Ikuta T, Wu M, Koyanagi R, Kawashima T, Tagawa K, Humphreys T, Fang GC, Fujiyama A, Saiga H, Lowe C, Worley K, Jenkins J, Schmutz J, Kirschner M, Rokhsar D, Satoh N, Gerhart J.

Curr Biol. 2012 Nov 6;22(21):2053-8. doi: 10.1016/j.cub.2012.08.052. Epub 2012 Oct 11.

16.
17.

A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii.

Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, Ohshima J, Sasai M, Kayama H, Okamoto T, Huang DC, Soldati-Favre D, Horie K, Takeda J, Takeda K.

Immunity. 2012 Aug 24;37(2):302-13. Epub 2012 Jul 12.

18.

Critical role of AIM2 in Mycobacterium tuberculosis infection.

Saiga H, Kitada S, Shimada Y, Kamiyama N, Okuyama M, Makino M, Yamamoto M, Takeda K.

Int Immunol. 2012 Oct;24(10):637-44. Epub 2012 Jun 13.

PMID:
22695634
19.

Tetraspanin CD151 protects against pulmonary fibrosis by maintaining epithelial integrity.

Tsujino K, Takeda Y, Arai T, Shintani Y, Inagaki R, Saiga H, Iwasaki T, Tetsumoto S, Jin Y, Ihara S, Minami T, Suzuki M, Nagatomo I, Inoue K, Kida H, Kijima T, Ito M, Kitaichi M, Inoue Y, Tachibana I, Takeda K, Okumura M, Hemler ME, Kumanogoh A.

Am J Respir Crit Care Med. 2012 Jul 15;186(2):170-80. doi: 10.1164/rccm.201201-0117OC. Epub 2012 May 16.

20.

ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.

Yamamoto M, Ma JS, Mueller C, Kamiyama N, Saiga H, Kubo E, Kimura T, Okamoto T, Okuyama M, Kayama H, Nagamune K, Takashima S, Matsuura Y, Soldati-Favre D, Takeda K.

J Exp Med. 2011 Jul 4;208(7):1533-46. doi: 10.1084/jem.20101660. Epub 2011 Jun 13.

21.
22.

Innate immune effectors in mycobacterial infection.

Saiga H, Shimada Y, Takeda K.

Clin Dev Immunol. 2011;2011:347594. doi: 10.1155/2011/347594. Epub 2011 Jan 12. Review.

23.

Segregation of germ layer fates by nuclear migration-dependent localization of Not mRNA.

Takatori N, Kumano G, Saiga H, Nishida H.

Dev Cell. 2010 Oct 19;19(4):589-98. doi: 10.1016/j.devcel.2010.09.003.

24.

[Potential of novel antimycobacterial immune factors, SLPI and lipocalin 2].

Saiga H, Takeda K.

Kekkaku. 2010 Jun;85(6):523-30. Review. Japanese.

PMID:
20662248
25.

A novel in vivo inducible dendritic cell ablation model in mice.

Okuyama M, Kayama H, Atarashi K, Saiga H, Kimura T, Waisman A, Yamamoto M, Takeda K.

Biochem Biophys Res Commun. 2010 Jul 2;397(3):559-63.

PMID:
20617552
26.

Limited functions of Hox genes in the larval development of the ascidian Ciona intestinalis.

Ikuta T, Satoh N, Saiga H.

Development. 2010 May;137(9):1505-13. doi: 10.1242/dev.046938. Epub 2010 Mar 24.

27.

Spatial and temporal expression of two transcriptional isoforms of Lhx3, a LIM class homeobox gene, during embryogenesis of two phylogenetically remote ascidians, Halocynthia roretzi and Ciona intestinalis.

Kobayashi M, Takatori N, Nakajima Y, Kumano G, Nishida H, Saiga H.

Gene Expr Patterns. 2010 Feb-Mar;10(2-3):98-104. doi: 10.1016/j.gep.2010.01.004. Epub 2010 Feb 1.

PMID:
20123132
28.

A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

Yamamoto M, Standley DM, Takashima S, Saiga H, Okuyama M, Kayama H, Kubo E, Ito H, Takaura M, Matsuda T, Soldati-Favre D, Takeda K.

J Exp Med. 2009 Nov 23;206(12):2747-60. doi: 10.1084/jem.20091703. Epub 2009 Nov 9.

29.

Ambulacrarian prototypical Hox and ParaHox gene complements of the indirect-developing hemichordate Balanoglossus simodensis.

Ikuta T, Miyamoto N, Saito Y, Wada H, Satoh N, Saiga H.

Dev Genes Evol. 2009 Jul;219(7):383-9. doi: 10.1007/s00427-009-0298-4. Epub 2009 Aug 11.

PMID:
19669790
30.

Evolutionary origins of blastoporal expression and organizer activity of the vertebrate gastrula organizer gene lhx1 and its ancient metazoan paralog lhx3.

Yasuoka Y, Kobayashi M, Kurokawa D, Akasaka K, Saiga H, Taira M.

Development. 2009 Jun;136(12):2005-14. doi: 10.1242/dev.028530. Epub 2009 May 13.

31.

Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium.

Saiga H, Nishimura J, Kuwata H, Okuyama M, Matsumoto S, Sato S, Matsumoto M, Akira S, Yoshikai Y, Honda K, Yamamoto M, Takeda K.

J Immunol. 2008 Dec 15;181(12):8521-7.

32.

Evolution of CUT class homeobox genes: insights from the genome of the amphioxus, Branchiostoma floridae.

Takatori N, Saiga H.

Int J Dev Biol. 2008;52(7):969-77. doi: 10.1387/ijdb.072541nt.

33.

Comprehensive survey and classification of homeobox genes in the genome of amphioxus, Branchiostoma floridae.

Takatori N, Butts T, Candiani S, Pestarino M, Ferrier DE, Saiga H, Holland PW.

Dev Genes Evol. 2008 Dec;218(11-12):579-90. doi: 10.1007/s00427-008-0245-9. Epub 2008 Sep 17.

PMID:
18797923
34.

The amphioxus genome illuminates vertebrate origins and cephalochordate biology.

Holland LZ, Albalat R, Azumi K, Benito-Gutiérrez E, Blow MJ, Bronner-Fraser M, Brunet F, Butts T, Candiani S, Dishaw LJ, Ferrier DE, Garcia-Fernàndez J, Gibson-Brown JJ, Gissi C, Godzik A, Hallböök F, Hirose D, Hosomichi K, Ikuta T, Inoko H, Kasahara M, Kasamatsu J, Kawashima T, Kimura A, Kobayashi M, Kozmik Z, Kubokawa K, Laudet V, Litman GW, McHardy AC, Meulemans D, Nonaka M, Olinski RP, Pancer Z, Pennacchio LA, Pestarino M, Rast JP, Rigoutsos I, Robinson-Rechavi M, Roch G, Saiga H, Sasakura Y, Satake M, Satou Y, Schubert M, Sherwood N, Shiina T, Takatori N, Tello J, Vopalensky P, Wada S, Xu A, Ye Y, Yoshida K, Yoshizaki F, Yu JK, Zhang Q, Zmasek CM, de Jong PJ, Osoegawa K, Putnam NH, Rokhsar DS, Satoh N, Holland PW.

Genome Res. 2008 Jul;18(7):1100-11. doi: 10.1101/gr.073676.107. Epub 2008 Jun 18. Erratum in: Genome Res. 2008 Aug;18(8):1380.

35.

Left-right asymmetric expression of Pitx is regulated by the asymmetric Nodal signaling through an intronic enhancer in Ciona intestinalis.

Yoshida K, Saiga H.

Dev Genes Evol. 2008 Jul;218(7):353-60. doi: 10.1007/s00427-008-0230-3. Epub 2008 Jun 11.

PMID:
18546017
36.

Potent antimycobacterial activity of mouse secretory leukocyte protease inhibitor.

Nishimura J, Saiga H, Sato S, Okuyama M, Kayama H, Kuwata H, Matsumoto S, Nishida T, Sawa Y, Akira S, Yoshikai Y, Yamamoto M, Takeda K.

J Immunol. 2008 Mar 15;180(6):4032-9.

39.

Myxococcus xanthus twin-arginine translocation system is important for growth and development.

Kimura Y, Saiga H, Hamanaka H, Matoba H.

Arch Microbiol. 2006 Feb;184(6):387-96. Epub 2005 Dec 6.

PMID:
16331440
40.

Organization of Hox genes in ascidians: present, past, and future.

Ikuta T, Saiga H.

Dev Dyn. 2005 Jun;233(2):382-9. Review.

41.
42.

A saturation screen for cis-acting regulatory DNA in the Hox genes of Ciona intestinalis.

Keys DN, Lee BI, Di Gregorio A, Harafuji N, Detter JC, Wang M, Kahsai O, Ahn S, Zhang C, Doyle SA, Satoh N, Satou Y, Saiga H, Christian AT, Rokhsar DS, Hawkins TL, Levine M, Richardson PM.

Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):679-83. Epub 2005 Jan 12.

43.

Ciona intestinalis Hox gene cluster: Its dispersed structure and residual colinear expression in development.

Ikuta T, Yoshida N, Satoh N, Saiga H.

Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15118-23. Epub 2004 Oct 6.

44.

Analysis of ascidian Not genes highlights their evolutionarily conserved and derived features of structure and expression in development.

Utsumi N, Shimojima Y, Saiga H.

Dev Genes Evol. 2004 Sep;214(9):460-5. Epub 2004 Jul 28.

PMID:
15338306
46.

Pigment cell lineage-specific expression activity of the ascidian tyrosinase-related gene.

Toyoda R, Kasai A, Sato S, Wada S, Saiga H, Ikeo K, Gojobori T, Numakunai T, Yamamoto H.

Gene. 2004 May 12;332:61-9.

PMID:
15145055
47.

Fluorescent in situ hybridization to ascidian chromosomes.

Shoguchi E, Ikuta T, Yoshizaki F, Satou Y, Satoh N, Asano K, Saiga H, Nishikata T.

Zoolog Sci. 2004 Feb;21(2):153-7.

PMID:
14993826
48.

Maternal macho-1 is an intrinsic factor that makes cell response to the same FGF signal differ between mesenchyme and notochord induction in ascidian embryos.

Kobayashi K, Sawada K, Yamamoto H, Wada S, Saiga H, Nishida H.

Development. 2003 Nov;130(21):5179-90. Epub 2003 Sep 3.

49.

A genomewide survey of developmentally relevant genes in Ciona intestinalis. II. Genes for homeobox transcription factors.

Wada S, Tokuoka M, Shoguchi E, Kobayashi K, Di Gregorio A, Spagnuolo A, Branno M, Kohara Y, Rokhsar D, Levine M, Saiga H, Satoh N, Satou Y.

Dev Genes Evol. 2003 Jun;213(5-6):222-34. Epub 2003 May 8.

PMID:
12736825
50.

Origin of mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 involved in the lectin complement pathway traced back to the invertebrate, amphioxus.

Endo Y, Nonaka M, Saiga H, Kakinuma Y, Matsushita A, Takahashi M, Matsushita M, Fujita T.

J Immunol. 2003 May 1;170(9):4701-7.

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