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Items: 38


Behçet's disease in Egypt: a multicenter nationwide study on 1526 adult patients and review of the literature.

Gheita TA, El-Latif EA, El-Gazzar II, Samy N, Hammam N, Abdel Noor RA, El-Shebeiny E, El-Najjar AR, Eesa NN, Salem MN, Ibrahim SE, El-Essawi DF, Elsaman AM, Fathi HM, Sallam RA, El-Shereef RR, Abd-Elazeem MI, Said EA, Khalil NM, Shahin D, El-Saadany HM, ElKhalifa MS, Nasef SI, Abdalla AM, Noshy N, Fawzy RM, Saad E, Moshrif AH, El-Shanawany AT, Abdel-Fattah YH, Khalil HM; Egyptian College of Rheumatology-Behçet’s Disease Study Group (ECR-BDSG).

Clin Rheumatol. 2019 May 22. doi: 10.1007/s10067-019-04570-w. [Epub ahead of print]


Sleep deprivation alters neutrophil functions and levels of Th1-related chemokines and CD4+ T cells in the blood.

Said EA, Al-Abri MA, Al-Saidi I, Al-Balushi MS, Al-Busaidi JZ, Al-Reesi I, Koh CY, Idris MA, Al-Jabri AA, Habbal O.

Sleep Breath. 2019 Apr 30. doi: 10.1007/s11325-019-01851-1. [Epub ahead of print]


Immune Responses to RNA Viruses.

Said EA, Diaz-Griffero F, Bonte D, Lamarre D, Al-Jabri AA.

J Immunol Res. 2018 Jun 12;2018:5473678. doi: 10.1155/2018/5473678. eCollection 2018. No abstract available.


Viruses Seen by Our Cells: The Role of Viral RNA Sensors.

Said EA, Tremblay N, Al-Balushi MS, Al-Jabri AA, Lamarre D.

J Immunol Res. 2018 Apr 30;2018:9480497. doi: 10.1155/2018/9480497. eCollection 2018. Review.


Altered blood cytokines, CD4 T cells, NK and neutrophils in patients with obstructive sleep apnea.

Said EA, Al-Abri MA, Al-Saidi I, Al-Balushi MS, Al-Busaidi JZ, Al-Reesi I, Koh CY, Hasson SS, Idris MA, Al-Jabri AA, Habbal O.

Immunol Lett. 2017 Oct;190:272-278. doi: 10.1016/j.imlet.2017.08.009. Epub 2017 Aug 19.


HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses.

Zhang Y, El-Far M, Dupuy FP, Abdel-Hakeem MS, He Z, Procopio FA, Shi Y, Haddad EK, Ancuta P, Sekaly RP, Said EA.

Sci Rep. 2016 Jul 7;6:29447. doi: 10.1038/srep29447.


High Levels of IgA Antibodies to Helicobacter Pylori among Omani Women during Pregnancy and after Delivery.

Al-Balushi MS, Said EA, Hasson SS, Al-Busaidi JZ, Al-Reesi I, Idris M, Al-Ghafri W, Al-Kalbani M, Al-Jabri AA.

Iran J Immunol. 2016 Jun;13(2):114-23. doi: IJIv13i2A4.


Increased CD86 but Not CD80 and PD-L1 Expression on Liver CD68+ Cells during Chronic HBV Infection.

Said EA, Al-Reesi I, Al-Riyami M, Al-Naamani K, Al-Sinawi S, Al-Balushi MS, Koh CY, Al-Busaidi JZ, Idris MA, Al-Jabri AA.

PLoS One. 2016 Jun 27;11(6):e0158265. doi: 10.1371/journal.pone.0158265. eCollection 2016.


Frequency of TLR4 (1063A/G and 1363C/T) polymorphisms in healthy and HIV-infected Omani individuals and their relationship to viral load and T cell count.

Said EA, Al-Yafei F, Zadjali F, Al-Balushi MS, Hasson SS, Al-Mahroqi SH, Koh CY, Al-Naamani K, Al-Busaidi JZ, Idris MA, Balkhair A, Al-Jabri AA.

Genet Mol Res. 2016 Apr 4;15(2). doi: 10.4238/gmr.15027671.


HLA-A68 and HLA-B15 alleles correlate with poor immune response among AIDS patients on combined antiretroviral therapy.

El-Beeli M, Al-Mahrooqi SH, Youssef RM, Zadjali F, Balkhair A, Al-Balushi MS, Said EA, Hasson SS, Al-Jabri AA.

Hum Immunol. 2016 Jun;77(6):490-7. doi: 10.1016/j.humimm.2016.04.009. Epub 2016 Apr 8.


A Potential Inhibitory Profile of Liver CD68+ Cells during HCV Infection as Observed by an Increased CD80 and PD-L1 but Not CD86 Expression.

Said EA, Al-Reesi I, Al-Riyami M, Al-Naamani K, Al-Sinawi S, Al-Balushi MS, Koh CY, Al-Busaidi JZ, Idris MA, Al-Jabri AA.

PLoS One. 2016 Apr 11;11(4):e0153191. doi: 10.1371/journal.pone.0153191. eCollection 2016.


Serum Interleukin-33 in Behcet's Disease: Its Relation to Disease Activity and Clinical Manifestations.

Fawzy RM, Said EA, Mohamed SM, Fouad NA, Akl EM.

Egypt J Immunol. 2015 Jun;22(2):1-8.


Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation.

El-Far M, Ancuta P, Routy JP, Zhang Y, Bakeman W, Bordi R, DaFonseca S, Said EA, Gosselin A, Tep TS, Eichbaum Q, van Grevenynghe J, Schwartz O, Freeman GJ, Haddad EK, Chomont N, Sékaly RP.

J Gen Virol. 2015 Jun;96(Pt 6):1463-77. doi: 10.1099/vir.0.000065. Epub 2015 Jan 27.


Fluctuation in the Levels of Immunoglobulin M and Immunoglobulin G Antibodies for Cardiolipin and β2-Glycoprotein among Healthy Pregnant Women.

Al-Balushi MS, Hasson SS, Said EA, Al-Busaidi JZ, Al-Daihani MS, Othman MS, Sallam TA, Idris MA, Al-Kalbani M, Woodhouse N, Al-Jabri AA.

Sultan Qaboos Univ Med J. 2014 Nov;14(4):e478-85. Epub 2014 Oct 14.


High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy.

Hasson SS, Al-Balushi MS, Al Yahmadi MH, Al-Busaidi JZ, Said EA, Othman MS, Sallam TA, Idris MA, Al-Jabri AA.

Asian Pac J Trop Biomed. 2014 Aug;4(8):610-3. doi: 10.12980/APJTB.4.201414B126.


Association of single-nucleotide polymorphisms in TLR7 (Gln11Leu) and TLR9 (1635A/G) with a higher CD4T cell count during HIV infection.

Said EA, Al-Yafei F, Zadjali F, Hasson SS, Al-Balushi MS, Al-Mahruqi S, Koh CY, Al-Naamani K, Al-Busaidi JZ, Idris MA, Balkhair A, Al-Jabri AA.

Immunol Lett. 2014 Jul;160(1):58-64. doi: 10.1016/j.imlet.2014.04.005. Epub 2014 Apr 16.


New genetic variants in the CCR5 gene and the distribution of known polymorphisms in Omani population.

Al-Mahruqi SH, Zadjali F, Koh CY, Balkhair A, Said EA, Al-Balushi MS, Hasson SS, Al-Jabri AA.

Int J Immunogenet. 2014 Feb;41(1):20-8. doi: 10.1111/iji.12081. Epub 2013 Aug 16.


Evaluation of anti-resistant activity of Auklandia (Saussurea lappa) root against some human pathogens.

Hasson SS, Al-Balushi MS, Alharthy K, Al-Busaidi JZ, Aldaihani MS, Othman MS, Said EA, Habal O, Sallam TA, Aljabri AA, Ahmedidris M.

Asian Pac J Trop Biomed. 2013 Jul;3(7):557-62. doi: 10.1016/S2221-1691(13)60113-6.


Neutralisation of Local Haemorrhage Induced by the Saw-Scaled Viper Echis carinatus sochureki Venom Using Ethanolic Extract of Hibiscus aethiopicus L.

Hasson SS, Al-Balushi MS, Said EA, Habbal O, Idris MA, Mothana RA, Sallam TA, Al-Jabri AA.

Evid Based Complement Alternat Med. 2012;2012:540671. doi: 10.1155/2012/540671. Epub 2012 May 15.


Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis.

van Grevenynghe J, Cubas RA, Noto A, DaFonseca S, He Z, Peretz Y, Filali-Mouhim A, Dupuy FP, Procopio FA, Chomont N, Balderas RS, Said EA, Boulassel MR, Tremblay CL, Routy JP, Sékaly RP, Haddad EK.

J Clin Invest. 2011 Oct;121(10):3877-88. doi: 10.1172/JCI59211. Epub 2011 Sep 19. Erratum in: J Clin Invest. 2012 Jul 2;122(7):2704.


Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7.

Monteiro P, Gosselin A, Wacleche VS, El-Far M, Said EA, Kared H, Grandvaux N, Boulassel MR, Routy JP, Ancuta P.

J Immunol. 2011 Apr 15;186(8):4618-30. doi: 10.4049/jimmunol.1004151. Epub 2011 Mar 11.


Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection.

Said EA, Dupuy FP, Trautmann L, Zhang Y, Shi Y, El-Far M, Hill BJ, Noto A, Ancuta P, Peretz Y, Fonseca SG, Van Grevenynghe J, Boulassel MR, Bruneau J, Shoukry NH, Routy JP, Douek DC, Haddad EK, Sekaly RP.

Nat Med. 2010 Apr;16(4):452-9. doi: 10.1038/nm.2106. Epub 2010 Mar 7.


Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection.

Gosselin A, Monteiro P, Chomont N, Diaz-Griffero F, Said EA, Fonseca S, Wacleche V, El-Far M, Boulassel MR, Routy JP, Sekaly RP, Ancuta P.

J Immunol. 2010 Feb 1;184(3):1604-16. doi: 10.4049/jimmunol.0903058. Epub 2009 Dec 30.


Semiquantitation of mouse dendritic cell migration in vivo using cellular MRI.

Dekaban GA, Snir J, Shrum B, de Chickera S, Willert C, Merrill M, Said EA, Sekaly RP, Foster PJ, O'Connell PJ.

J Immunother. 2009 Apr;32(3):240-51. doi: 10.1097/CJI.0b013e318197b2a0.


Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses.

Gaucher D, Therrien R, Kettaf N, Angermann BR, Boucher G, Filali-Mouhim A, Moser JM, Mehta RS, Drake DR 3rd, Castro E, Akondy R, Rinfret A, Yassine-Diab B, Said EA, Chouikh Y, Cameron MJ, Clum R, Kelvin D, Somogyi R, Greller LD, Balderas RS, Wilkinson P, Pantaleo G, Tartaglia J, Haddad EK, Sékaly RP.

J Exp Med. 2008 Dec 22;205(13):3119-31. doi: 10.1084/jem.20082292. Epub 2008 Dec 1.


Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection.

van Grevenynghe J, Halwani R, Chomont N, Ancuta P, Peretz Y, Tanel A, Procopio FA, shi Y, Said EA, Haddad EK, Sekaly RP.

Semin Immunol. 2008 Jun;20(3):196-203. doi: 10.1016/j.smim.2008.07.008. Epub 2008 Aug 30. Review.


Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.

van Grevenynghe J, Procopio FA, He Z, Chomont N, Riou C, Zhang Y, Gimmig S, Boucher G, Wilkinson P, Shi Y, Yassine-Diab B, Said EA, Trautmann L, El Far M, Balderas RS, Boulassel MR, Routy JP, Haddad EK, Sekaly RP.

Nat Med. 2008 Mar;14(3):266-74. doi: 10.1038/nm1728. Epub 2008 Mar 2.


Programmed death 1: a critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections.

Trautmann L, Said EA, Halwani R, Janbazian L, Chomont N, El-Far M, Breton G, Haddad EK, Sekaly RP.

Curr Opin HIV AIDS. 2007 May;2(3):219-27. doi: 10.1097/COH.0b013e3280ebb5c9.


Generation and maintenance of human memory cells during viral infection.

Halwani R, Doroudchi M, Yassine-Diab B, Janbazian L, Shi Y, Said EA, Haddad EK, Sékaly RP.

Springer Semin Immunopathol. 2006 Nov;28(3):197-208. Epub 2006 Sep 12. Review.


Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction.

Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, Bessette B, Boulassel MR, Delwart E, Sepulveda H, Balderas RS, Routy JP, Haddad EK, Sekaly RP.

Nat Med. 2006 Oct;12(10):1198-202. Epub 2006 Aug 20. Erratum in: Nat Med. 2006 Nov;12(11):1329.


Pleiotrophin inhibits HIV infection by binding the cell surface-expressed nucleolin.

Said EA, Courty J, Svab J, Delbé J, Krust B, Hovanessian AG.

FEBS J. 2005 Sep;272(18):4646-59.


The caveolin-1 binding domain of HIV-1 glycoprotein gp41 is an efficient B cell epitope vaccine candidate against virus infection.

Hovanessian AG, Briand JP, Said EA, Svab J, Ferris S, Dali H, Muller S, Desgranges C, Krust B.

Immunity. 2004 Nov;21(5):617-27.


Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells.

Legrand D, Vigié K, Said EA, Elass E, Masson M, Slomianny MC, Carpentier M, Briand JP, Mazurier J, Hovanessian AG.

Eur J Biochem. 2004 Jan;271(2):303-17.


The anti-HIV cytokine midkine binds the cell surface-expressed nucleolin as a low affinity receptor.

Said EA, Krust B, Nisole S, Svab J, Briand JP, Hovanessian AG.

J Biol Chem. 2002 Oct 4;277(40):37492-502. Epub 2002 Jul 29.


The anti-HIV pentameric pseudopeptide HB-19 binds the C-terminal end of nucleolin and prevents anchorage of virus particles in the plasma membrane of target cells.

Nisole S, Said EA, Mische C, Prevost MC, Krust B, Bouvet P, Bianco A, Briand JP, Hovanessian AG.

J Biol Chem. 2002 Jun 7;277(23):20877-86. Epub 2002 Mar 27.


Effect of addition antimicrobial agents to denture reliners.

el-Charkawi H, el-Said EA, Safouh HM, el-Raghi N.

Egypt Dent J. 1994 Jul;40(3):785-90.


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