Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 55

1.

Single-cell exomes in an index case of amp1q21 multiple myeloma reveal more diverse mutanomes than the whole population.

Bryant D, Tapper W, Weston-Bell NJ, Bolomsky A, Song L, Xu S, Collins AR, Zojer N, Sahota SS.

Blood. 2018 Jul 12;132(2):232-235. doi: 10.1182/blood-2018-01-829291. Epub 2018 May 18. No abstract available.

2.

Tracking B-Cell Repertoires and Clonal Histories in Normal and Malignant Lymphocytes.

Weston-Bell NJ, Cowan G, Sahota SS.

Methods Mol Biol. 2017;1623:281-301. doi: 10.1007/978-1-4939-7095-7_21.

PMID:
28589363
3.

Tumour infiltrating lymphocytes correlate with improved survival in patients with oesophageal adenocarcinoma.

Noble F, Mellows T, McCormick Matthews LH, Bateman AC, Harris S, Underwood TJ, Byrne JP, Bailey IS, Sharland DM, Kelly JJ, Primrose JN, Sahota SS, Bateman AR, Thomas GJ, Ottensmeier CH.

Cancer Immunol Immunother. 2016 Jun;65(6):651-62. doi: 10.1007/s00262-016-1826-5. Epub 2016 Mar 28.

4.

Exome Sequencing in Classic Hairy Cell Leukaemia Reveals Widespread Variation in Acquired Somatic Mutations between Individual Tumours Apart from the Signature BRAF V(600)E Lesion.

Weston-Bell NJ, Tapper W, Gibson J, Bryant D, Moreno Y, John M, Ennis S, Kluin-Nelemans HC, Collins AR, Sahota SS.

PLoS One. 2016 Feb 12;11(2):e0149162. doi: 10.1371/journal.pone.0149162. eCollection 2016.

5.

Massive parallel IGHV gene sequencing reveals a germinal center pathway in origins of human multiple myeloma.

Cowan G, Weston-Bell NJ, Bryant D, Seckinger A, Hose D, Zojer N, Sahota SS.

Oncotarget. 2015 May 30;6(15):13229-40.

6.

Monoclonal paraprotein influences baseline B-cell repertoire diversity and perturbates influenza vaccination-induced B-cell response.

Tete SM, Kipling D, Westra J, de Haan A, Bijl M, Dunn-Walters DK, Sahota SS, Bos NA.

Exp Hematol. 2015 Jun;43(6):439-47.e1. doi: 10.1016/j.exphem.2015.02.005. Epub 2015 Mar 18.

PMID:
25795522
7.

Immune defects in the risk of infection and response to vaccination in monoclonal gammopathy of undetermined significance and multiple myeloma.

Tete SM, Bijl M, Sahota SS, Bos NA.

Front Immunol. 2014 Jun 3;5:257. doi: 10.3389/fimmu.2014.00257. eCollection 2014. Review.

8.

Variant B cell receptor isotype functions differ in hairy cell leukemia with mutated BRAF and IGHV genes.

Weston-Bell NJ, Forconi F, Kluin-Nelemans HC, Sahota SS.

PLoS One. 2014 Jan 30;9(1):e86556. doi: 10.1371/journal.pone.0086556. eCollection 2014.

9.

Exome sequencing in tracking clonal evolution in multiple myeloma following therapy.

Weston-Bell N, Gibson J, John M, Ennis S, Pfeifer S, Cezard T, Ludwig H, Collins A, Zojer N, Sahota SS.

Leukemia. 2013 Apr;27(5):1188-91. doi: 10.1038/leu.2012.287. Epub 2012 Oct 9. No abstract available.

PMID:
23147253
10.

Induction of indoleamine-2,3 dioxygenase in bone marrow stromal cells inhibits myeloma cell growth.

Pfeifer S, Schreder M, Bolomsky A, Graffi S, Fuchs D, Sahota SS, Ludwig H, Zojer N.

J Cancer Res Clin Oncol. 2012 Nov;138(11):1821-30. doi: 10.1007/s00432-012-1259-2. Epub 2012 Jun 22.

PMID:
22722711
11.

Hairy cell leukemia cell lines expressing annexin A1 and displaying B-cell receptor signals characteristic of primary tumor cells lack the signature BRAF mutation to reveal unrepresentative origins.

Weston-Bell NJ, Hendriks D, Sugiyarto G, Bos NA, Kluin-Nelemans HC, Forconi F, Sahota SS.

Leukemia. 2013 Jan;27(1):241-5. doi: 10.1038/leu.2012.163. Epub 2012 Jun 18. No abstract available.

PMID:
22705994
12.

Cancer testis antigens in newly diagnosed and relapse multiple myeloma: prognostic markers and potential targets for immunotherapy.

van Duin M, Broyl A, de Knegt Y, Goldschmidt H, Richardson PG, Hop WC, van der Holt B, Joseph-Pietras D, Mulligan G, Neuwirth R, Sahota SS, Sonneveld P.

Haematologica. 2011 Nov;96(11):1662-9. doi: 10.3324/haematol.2010.037978. Epub 2011 Jul 26.

13.

Evaluating the clonal hierarchy in light-chain multiple myeloma: implications against the myeloma stem cell hypothesis.

Pfeifer S, Perez-Andres M, Ludwig H, Sahota SS, Zojer N.

Leukemia. 2011 Jul;25(7):1213-6. doi: 10.1038/leu.2011.70. Epub 2011 Apr 15. No abstract available.

PMID:
21494259
14.

DNA vaccines to target the cancer testis antigen PASD1 in human multiple myeloma.

Joseph-Pietras D, Gao Y, Zojer N, Ait-Tahar K, Banham AH, Pulford K, Rice J, Savelyeva N, Sahota SS.

Leukemia. 2010 Nov;24(11):1951-9. doi: 10.1038/leu.2010.196. Epub 2010 Sep 23.

PMID:
20861911
15.

Lack of allelic exclusion by secondary rearrangements of tumour B-cell receptor light chains in hairy cell leukaemia.

Sozzi E, Amato T, Sahota SS, Nuti S, Raspadori D, Sicuranza A, Cencini E, Tosi P, Lauria F, Forconi F.

Hematol Oncol. 2011 Mar;29(1):31-7. doi: 10.1002/hon.952.

PMID:
20658474
16.

Modelling a role for IgH chromosomal translocations in the pathogenesis of B-cell tumours.

Sahota SS.

Leuk Res. 2010 Aug;34(8):965-6. doi: 10.1016/j.leukres.2009.12.016. Epub 2010 Jan 31. No abstract available.

PMID:
20122732
17.

Defining origins of malignant B cells: a new circulating normal human IgM(+)D(+) B-cell subset lacking CD27 expression and displaying somatically mutated IGHV genes as a relevant memory population.

Weston-Bell N, Townsend M, Di Genova G, Forconi F, Sahota SS.

Leukemia. 2009 Nov;23(11):2075-80. doi: 10.1038/leu.2009.178. Epub 2009 Sep 24.

PMID:
19776762
18.

CD27 in defining memory B-cell origins in Waldenström's macroglobulinemia.

Sahota SS, Babbage G, Weston-Bell NJ.

Clin Lymphoma Myeloma. 2009 Mar;9(1):33-5. doi: 10.3816/CLM.2009.n.007.

PMID:
19362967
19.

Selective influences in the expressed immunoglobulin heavy and light chain gene repertoire in hairy cell leukemia.

Forconi F, Sozzi E, Rossi D, Sahota SS, Amato T, Raspadori D, Trentin L, Leoncini L, Gaidano G, Lauria F.

Haematologica. 2008 May;93(5):697-705. doi: 10.3324/haematol.12282. Epub 2008 Apr 2.

20.

A VH4-34+ myeloma protein with weak autoreactivity.

Frøyland M, Thompson KM, Thorpe SJ, Sahota SS, Gedde-Dahl T, Bogen B.

Haematologica. 2007 May;92(5):690-3.

21.

IgM-expressing Waldenstrom's macroglobulinemia tumor cells reveal a potential for isotype switch events in vivo.

Babbage G, Townsend M, Zojer N, Mockridge IC, Garand R, Barlogie B, Shaughnessy J Jr, Stevenson FK, Sahota SS.

Leukemia. 2007 Apr;21(4):827-30. Epub 2007 Feb 8. No abstract available.

PMID:
17287856
22.

PASD1 is a potential multiple myeloma-associated antigen.

Sahota SS, Goonewardena CM, Cooper CD, Liggins AP, Ait-Tahar K, Zojer N, Stevenson FK, Banham AH, Pulford K.

Blood. 2006 Dec 1;108(12):3953-5. No abstract available.

PMID:
17114574
23.

Lineage complexity in multiple myeloma?

Sahota SS, Stevenson FK.

Leuk Lymphoma. 2006 Sep;47(9):1997-8. Review. No abstract available.

PMID:
17065026
24.

Novel Ig V gene features of t(14;18) and t(3;14) de novo diffuse large B-cell lymphoma displaying germinal center-B cell like and non-germinal center-B cell like markers.

Jardin F, Sahota SS, Ruminy P, Parmentier F, Picquenot JM, Rainville V, Buchonnet G, Leprêtre S, Tilly H, Bastard C.

Leukemia. 2006 Nov;20(11):2070-4. Epub 2006 Sep 14. No abstract available.

PMID:
16990787
25.

Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines.

Babbage G, Ottensmeier CH, Blaydes J, Stevenson FK, Sahota SS.

Cancer Res. 2006 Apr 15;66(8):3996-4000.

26.

Immunoglobulin gene analysis in polyneuropathy associated with IgM monoclonal gammopathy.

Eurelings M, Notermans NC, Lokhorst HM, van Kessel B, Jacobs BC, Wokke JH, Sahota SS, Bloem AC.

J Neuroimmunol. 2006 Jun;175(1-2):152-9. Epub 2006 Mar 6.

PMID:
16600385
27.

Targeted somatic mutation of the BCL6 proto-oncogene and its impact on lymphomagenesis.

Jardin F, Sahota SS.

Hematology. 2005 Apr;10(2):115-29. Review.

PMID:
16019457
28.

Idiotype gene rescue in follicular lymphoma.

McCann K, Sahota SS, Stevenson FK, Ottensmeier CH.

Methods Mol Med. 2005;115:145-71.

PMID:
15998967
29.

Determining mutational status of immunoglobulin v genes in chronic lymphocytic leukemia: a useful prognostic indicator.

Sahota SS, Babbage G, Zojer N, Ottensmeier CH, Stevenson FK.

Methods Mol Med. 2005;115:129-44.

PMID:
15998966
30.

Identification and assembly of V genes as idiotype-specific DNA fusion vaccines in multiple myeloma.

Sahota SS, Townsend M, Stevenson FK.

Methods Mol Med. 2005;113:105-19.

PMID:
15968098
31.

Immunoglobulin M myeloma: evaluation of molecular features and cytokine expression.

Konduri K, Sahota SS, Babbage G, Tong AW, Kumar P, Newman JT, Stone MJ.

Clin Lymphoma. 2005 Mar;5(4):285-9.

PMID:
15794867
32.

Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch.

Forconi F, Sahota SS, Raspadori D, Ippoliti M, Babbage G, Lauria F, Stevenson FK.

Blood. 2004 Nov 15;104(10):3312-7. Epub 2004 Jul 29.

PMID:
15284115
33.

Revisiting the definition of somatic mutational status in B-cell tumors: does 98% homology mean that a V(H)-gene is unmutated?

Forconi F, Sahota SS, Lauria F, Stevenson FK.

Leukemia. 2004 Apr;18(4):882-3. No abstract available.

PMID:
14973503
34.

Mantle cell lymphoma with t(11;14) and unmutated or mutated VH genes expresses AID and undergoes isotype switch events.

Babbage G, Garand R, Robillard N, Zojer N, Stevenson FK, Sahota SS.

Blood. 2004 Apr 1;103(7):2795-8. Epub 2003 Oct 9.

PMID:
14551145
35.

Intronic BCL-6 mutations are preferentially targeted to the translocated allele in t(3;14)(q27;q32) non-Hodgkin B-cell lymphoma.

Jardin F, Bastard C, Contentin N, Parmentier F, Picquenot JM, Tilly H, Stevenson FK, Sahota SS.

Blood. 2003 Sep 1;102(5):1872-6. Epub 2003 May 29.

PMID:
12775568
36.

Origins of the malignant clone in typical Waldenstrom's macroglobulinemia.

Sahota SS, Forconi F, Ottensmeier CH, Stevenson FK.

Semin Oncol. 2003 Apr;30(2):136-41.

PMID:
12720123
37.

Patterns of somatic mutations in VH genes reveal pathways of clonal transformation from MGUS to multiple myeloma.

Zojer N, Ludwig H, Fiegl M, Stevenson FK, Sahota SS.

Blood. 2003 May 15;101(10):4137-9. Epub 2003 Jan 16.

PMID:
12531815
38.

Frequent expression of HAGE in presentation chronic myeloid leukaemias.

Adams SP, Sahota SS, Mijovic A, Czepulkowski B, Padua RA, Mufti GJ, Guinn BA.

Leukemia. 2002 Nov;16(11):2238-42.

39.

Insight into the potential for DNA idiotypic fusion vaccines designed for patients by analysing xenogeneic anti-idiotypic antibody responses.

Forconi F, King CA, Sahota SS, Kennaway CK, Russell NH, Stevenson FK.

Immunology. 2002 Sep;107(1):39-45.

40.

Typical Waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events.

Sahota SS, Forconi F, Ottensmeier CH, Provan D, Oscier DG, Hamblin TJ, Stevenson FK.

Blood. 2002 Aug 15;100(4):1505-7.

PMID:
12149241
41.

The occurrence and significance of V gene mutations in B cell-derived human malignancy.

Stevenson FK, Sahota SS, Ottensmeier CH, Zhu D, Forconi F, Hamblin TJ.

Adv Cancer Res. 2001;83:81-116. Review.

PMID:
11665722
42.

Tumor cells of hairy cell leukemia express multiple clonally related immunoglobulin isotypes via RNA splicing.

Forconi F, Sahota SS, Raspadori D, Mockridge CI, Lauria F, Stevenson FK.

Blood. 2001 Aug 15;98(4):1174-81.

PMID:
11493467
43.

DNA vaccination against cancer antigens.

Stevenson FK, Zhu D, Spellerberg MB, Rice J, King CA, Thompsett AR, Sahota SS, Hamblin TJ.

Ernst Schering Res Found Workshop. 2000;(30):119-36. Review. No abstract available.

PMID:
10943320
44.

IgG-secreting lymphoplasmacytoid leukaemia: a B-cell disorder with extensively mutated VH genes undergoing Ig isotype-switching frequently associated with trisomy 12.

Garand R, Sahota SS, Avet-Loiseau H, Talmant P, Robillard N, Moreau A, Gaillard F, Stevenson FK, Bataille R.

Br J Haematol. 2000 Apr;109(1):71-80.

PMID:
10848784
45.

Somatic mutation of bcl-6 genes can occur in the absence of V(H) mutations in chronic lymphocytic leukemia.

Sahota SS, Davis Z, Hamblin TJ, Stevenson FK.

Blood. 2000 Jun 1;95(11):3534-40.

PMID:
10828040
46.

V(H) gene analysis of IgM-secreting myeloma indicates an origin from a memory cell undergoing isotype switch events.

Sahota SS, Garand R, Mahroof R, Smith A, Juge-Morineau N, Stevenson FK, Bataille R.

Blood. 1999 Aug 1;94(3):1070-6.

PMID:
10419900
47.

B cell maturation in relation to multiple myeloma.

Stevenson FK, Sahota SS.

Pathol Biol (Paris). 1999 Feb;47(2):89-97. Review.

PMID:
10192875
48.

DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma.

King CA, Spellerberg MB, Zhu D, Rice J, Sahota SS, Thompsett AR, Hamblin TJ, Radl J, Stevenson FK.

Nat Med. 1998 Nov;4(11):1281-6.

PMID:
9809552
49.
50.

Myeloma VL and VH gene sequences reveal a complementary imprint of antigen selection in tumor cells.

Sahota SS, Leo R, Hamblin TJ, Stevenson FK.

Blood. 1997 Jan 1;89(1):219-26.

PMID:
8978295

Supplemental Content

Loading ...
Support Center