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Items: 1 to 50 of 106

1.

Simultaneous Inhibition of Angiopoietin-2 and Vascular Endothelial Growth Factor-A with Faricimab in Diabetic Macular Edema: BOULEVARD Phase 2 Randomized Trial.

Sahni J, Patel SS, Dugel PU, Khanani AM, Jhaveri CD, Wykoff CC, Hershberger VS, Pauly-Evers M, Sadikhov S, Szczesny P, Schwab D, Nogoceke E, Osborne A, Weikert R, Fauser S.

Ophthalmology. 2019 Aug;126(8):1155-1170. doi: 10.1016/j.ophtha.2019.03.023. Epub 2019 Mar 21.

2.

Targeting BCL-xL improves the efficacy of bromodomain and extra-terminal protein inhibitors in triple-negative breast cancer by eliciting the death of senescent cells.

Gayle SS, Sahni JM, Webb BM, Weber-Bonk KL, Shively MS, Spina R, Bar EE, Summers MK, Keri RA.

J Biol Chem. 2019 Jan 18;294(3):875-886. doi: 10.1074/jbc.RA118.004712. Epub 2018 Nov 27.

PMID:
30482844
3.

Targeting bromodomain and extraterminal proteins in breast cancer.

Sahni JM, Keri RA.

Pharmacol Res. 2018 Mar;129:156-176. doi: 10.1016/j.phrs.2017.11.015. Epub 2017 Nov 16. Review.

4.

BETi induction of mitotic catastrophe: towing the LIN9.

Gayle SS, Sahni JM, Keri RA.

Oncoscience. 2017 Oct 23;4(9-10):128-130. doi: 10.18632/oncoscience.372. eCollection 2017 Sep. No abstract available.

5.

Novel pathogenic mutations in C1QTNF5 support a dominant negative disease mechanism in late-onset retinal degeneration.

Stanton CM, Borooah S, Drake C, Marsh JA, Campbell S, Lennon A, Soares DC, Vallabh NA, Sahni J, Cideciyan AV, Dhillon B, Vitart V, Jacobson SG, Wright AF, Hayward C.

Sci Rep. 2017 Sep 22;7(1):12147. doi: 10.1038/s41598-017-11898-3.

6.

Mitotic Vulnerability in Triple-Negative Breast Cancer Associated with LIN9 Is Targetable with BET Inhibitors.

Sahni JM, Gayle SS, Webb BM, Weber-Bonk KL, Seachrist DD, Singh S, Sizemore ST, Restrepo NA, Bebek G, Scacheri PC, Varadan V, Summers MK, Keri RA.

Cancer Res. 2017 Oct 1;77(19):5395-5408. doi: 10.1158/0008-5472.CAN-17-1571. Epub 2017 Aug 14.

7.

Reduced narcotic and sedative utilization in a NICU after implementation of pain management guidelines.

Rana D, Bellflower B, Sahni J, Kaplan AJ, Owens NT, Arrindell EL Jr, Talati AJ, Dhanireddy R.

J Perinatol. 2017 Sep;37(9):1038-1042. doi: 10.1038/jp.2017.88. Epub 2017 Jun 15.

PMID:
28617422
8.

Homology-Directed Recombination for Enhanced Engineering of Chimeric Antigen Receptor T Cells.

Hale M, Lee B, Honaker Y, Leung WH, Grier AE, Jacobs HM, Sommer K, Sahni J, Jackson SW, Scharenberg AM, Astrakhan A, Rawlings DJ.

Mol Ther Methods Clin Dev. 2017 Jan 10;4:192-203. doi: 10.1016/j.omtm.2016.12.008. eCollection 2017 Mar 17.

9.

Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T Cells.

Hale M, Mesojednik T, Romano Ibarra GS, Sahni J, Bernard A, Sommer K, Scharenberg AM, Rawlings DJ, Wagner TA.

Mol Ther. 2017 Mar 1;25(3):570-579. doi: 10.1016/j.ymthe.2016.12.023. Epub 2017 Jan 28.

10.

Phase I Trial of Anti-Vascular Endothelial Growth Factor/Anti-angiopoietin 2 Bispecific Antibody RG7716 for Neovascular Age-Related Macular Degeneration.

Chakravarthy U, Bailey C, Brown D, Campochiaro P, Chittum M, Csaky K, Tufail A, Yates P, Cech P, Giraudon M, Delmar P, Szczesny P, Sahni J, Boulay A, Nagel S, Fürst-Recktenwald S, Schwab D.

Ophthalmol Retina. 2017 Nov - Dec;1(6):474-485. doi: 10.1016/j.oret.2017.03.003. Epub 2017 May 23.

PMID:
31047438
11.

Safety and acceptability of an organic light-emitting diode sleep mask as a potential therapy for retinal disease.

Sahni JN, Czanner G, Gutu T, Taylor SA, Bennett KM, Wuerger SM, Grierson I, Murray-Dunning C, Holland MN, Harding SP; Medscape.

Eye (Lond). 2017 Jan;31(1):97-106. doi: 10.1038/eye.2016.259. Epub 2016 Dec 16.

12.

Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases.

Sahni JM, Gayle SS, Bonk KL, Vite LC, Yori JL, Webb B, Ramos EK, Seachrist DD, Landis MD, Chang JC, Bradner JE, Keri RA.

J Biol Chem. 2016 Nov 4;291(45):23756-23768. Epub 2016 Sep 20.

13.

The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity.

Jansen C, Sahni J, Suzuki S, Horgen FD, Penner R, Fleig A.

Sci Rep. 2016 Sep 15;6:33459. doi: 10.1038/srep33459.

14.

Near-infrared reflectance and autofluorescence imaging characteristics of choroidal nevi.

Vallabh NA, Sahni JN, Parkes CK, Czanner G, Heimann H, Damato B.

Eye (Lond). 2016 Dec;30(12):1593-1597. doi: 10.1038/eye.2016.183. Epub 2016 Sep 2.

15.

Aural hygiene practices among underprivileged children of Delhi.

Bhat A, Ray TK, Sahni JK.

Natl Med J India. 2015 Nov-Dec;28(6):280-1.

PMID:
27294451
16.

High Efficiency CRISPR/Cas9-mediated Gene Editing in Primary Human T-cells Using Mutant Adenoviral E4orf6/E1b55k "Helper" Proteins.

Gwiazda KS, Grier AE, Sahni J, Burleigh SM, Martin U, Yang JG, Popp NA, Krutein MC, Khan IF, Jacoby K, Jensen MC, Rawlings DJ, Scharenberg AM.

Mol Ther. 2016 Sep 29;24(9):1570-80. doi: 10.1038/mt.2016.105. Epub 2016 May 16.

17.

pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences.

Grier AE, Burleigh S, Sahni J, Clough CA, Cardot V, Choe DC, Krutein MC, Rawlings DJ, Jensen MC, Scharenberg AM, Jacoby K.

Mol Ther Nucleic Acids. 2016 Apr 19;5:e306. doi: 10.1038/mtna.2016.21.

18.

Hearing Sensitivity in 40-60 Years Old Hypertensive Male Adults.

Sharma K, Gandhi A, Ahluwalia H, Sahni JK.

Indian J Physiol Pharmacol. 2015 Apr-Jun;59(2):242-6.

PMID:
26685515
19.

A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN).

Chakravarthy U, Harding SP, Rogers CA, Downes S, Lotery AJ, Dakin HA, Culliford L, Scott LJ, Nash RL, Taylor J, Muldrew A, Sahni J, Wordsworth S, Raftery J, Peto T, Reeves BC.

Health Technol Assess. 2015 Oct;19(78):1-298. doi: 10.3310/hta19780.

20.

Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.

Sather BD, Romano Ibarra GS, Sommer K, Curinga G, Hale M, Khan IF, Singh S, Song Y, Gwiazda K, Sahni J, Jarjour J, Astrakhan A, Wagner TA, Scharenberg AM, Rawlings DJ.

Sci Transl Med. 2015 Sep 30;7(307):307ra156. doi: 10.1126/scitranslmed.aac5530.

21.

Design, characterization, and evaluation of intranasal delivery of ropinirole-loaded mucoadhesive nanoparticles for brain targeting.

Jafarieh O, Md S, Ali M, Baboota S, Sahni JK, Kumari B, Bhatnagar A, Ali J.

Drug Dev Ind Pharm. 2015;41(10):1674-81. doi: 10.3109/03639045.2014.991400. Epub 2014 Dec 11.

PMID:
25496439
22.

Nanosizing of valsartan by high pressure homogenization to produce dissolution enhanced nanosuspension: pharmacokinetics and pharmacodyanamic study.

Gora S, Mustafa G, Sahni JK, Ali J, Baboota S.

Drug Deliv. 2016;23(3):940-50. doi: 10.3109/10717544.2014.923066. Epub 2014 Jun 17.

PMID:
24937379
23.

Resveratrol: review on therapeutic potential and recent advances in drug delivery.

Pangeni R, Sahni JK, Ali J, Sharma S, Baboota S.

Expert Opin Drug Deliv. 2014 Aug;11(8):1285-98. doi: 10.1517/17425247.2014.919253. Epub 2014 May 15. Review.

PMID:
24830814
24.

Pharmacoscintigraphic evaluation of potential of lipid nanocarriers for nose-to-brain delivery of antidepressant drug.

Alam MI, Baboota S, Ahuja A, Ali M, Ali J, Sahni JK, Bhatnagar A.

Int J Pharm. 2014 Aug 15;470(1-2):99-106. doi: 10.1016/j.ijpharm.2014.05.004. Epub 2014 May 6.

PMID:
24810241
25.

Nanostructured lipid (NLCs) carriers as a bioavailability enhancement tool for oral administration.

Gaba B, Fazil M, Ali A, Baboota S, Sahni JK, Ali J.

Drug Deliv. 2015;22(6):691-700. doi: 10.3109/10717544.2014.898110. Epub 2014 Mar 27. Review.

PMID:
24670099
26.

Optimised nanoformulation of bromocriptine for direct nose-to-brain delivery: biodistribution, pharmacokinetic and dopamine estimation by ultra-HPLC/mass spectrometry method.

Md S, Haque S, Fazil M, Kumar M, Baboota S, Sahni JK, Ali J.

Expert Opin Drug Deliv. 2014 Jun;11(6):827-42. doi: 10.1517/17425247.2014.894504. Epub 2014 Mar 22.

PMID:
24655115
27.

Effect of high-pressure homogenization on formulation of TPGS loaded nanoemulsion of rutin - pharmacodynamic and antioxidant studies.

Sharma S, Sahni JK, Ali J, Baboota S.

Drug Deliv. 2015;22(4):541-51. doi: 10.3109/10717544.2014.893382. Epub 2014 Mar 13.

PMID:
24625264
28.

Value of anti-VEGF treatment in choroidal neovascularization associated with autosomal recessive bestrophinopathy.

Madhusudhan S, Hussain A, Sahni JN.

Digit J Ophthalmol. 2013 Dec 30;19(4):59-63. doi: 10.5693/djo.02.2013.09.001. eCollection 2013.

29.

Bilateral Choanal Atresia: Is it Really a Surgical Emergency?

Kumar S, Gupta S, Naglot S, Sahni JK.

Indian J Otolaryngol Head Neck Surg. 2013 Aug;65(Suppl 2):205-9. doi: 10.1007/s12070-011-0304-9. Epub 2011 Sep 21.

30.

Bisphosphonates: therapeutics potential and recent advances in drug delivery.

Fazil M, Baboota S, Sahni JK, Ameeduzzafar, Ali J.

Drug Deliv. 2015 Jan;22(1):1-9. doi: 10.3109/10717544.2013.870259. Epub 2014 Jan 10. Review.

PMID:
24404750
31.

Development and evaluation of brain targeted intranasal alginate nanoparticles for treatment of depression.

Haque S, Md S, Sahni JK, Ali J, Baboota S.

J Psychiatr Res. 2014 Jan;48(1):1-12. doi: 10.1016/j.jpsychires.2013.10.011. Epub 2013 Oct 23.

PMID:
24231512
32.

Response to Fajgenbaum.

Davies AJ, Kelly SP, Naylor SG, Bhatt PR, Mathews JP, Sahni J, Haslett R, McKibbin M.

Eye (Lond). 2013 Dec;27(12):1421. doi: 10.1038/eye.2013.220. Epub 2013 Oct 11. No abstract available.

33.

Insights into direct nose to brain delivery: current status and future perspective.

Mittal D, Ali A, Md S, Baboota S, Sahni JK, Ali J.

Drug Deliv. 2014 Mar;21(2):75-86. doi: 10.3109/10717544.2013.838713. Epub 2013 Oct 9. Review.

PMID:
24102636
34.

Transient receptor potential melastatin 7 is involved in oestrogen receptor-negative metastatic breast cancer cells migration through its kinase domain.

Guilbert A, Gautier M, Dhennin-Duthille I, Rybarczyk P, Sahni J, Sevestre H, Scharenberg AM, Ouadid-Ahidouch H.

Eur J Cancer. 2013 Nov;49(17):3694-707. doi: 10.1016/j.ejca.2013.07.008. Epub 2013 Aug 1.

PMID:
23910495
35.

Intranasal infusion of nanostructured lipid carriers (NLC) containing CNS acting drug and estimation in brain and blood.

Alam MI, Baboota S, Ahuja A, Ali M, Ali J, Sahni JK.

Drug Deliv. 2013 Aug;20(6):247-51. doi: 10.3109/10717544.2013.822945.

PMID:
23869788
36.

Oral delivery of therapeutic proteins and peptides: a review on recent developments.

Gupta S, Jain A, Chakraborty M, Sahni JK, Ali J, Dang S.

Drug Deliv. 2013 Aug;20(6):237-46. doi: 10.3109/10717544.2013.819611. Review.

PMID:
23869787
37.

Protocol of an observational study to evaluate diabetic nephropathy through detection of microalbuminuria in Indian patients.

Gokulnath, Sahay M, Kalra S, Vishwanathan V, Zargar AH, Talwalkar PG, Wangnoo SK, Maji D, Kumar GV, Sharma RK, Chafekar D, Mohan B, Bantwal G, Bansali A, Sahni JS.

Indian J Endocrinol Metab. 2013 May;17(3):496-504. doi: 10.4103/2230-8210.111655.

38.

Exploring targeted pulmonary delivery for treatment of lung cancer.

Goel A, Baboota S, Sahni JK, Ali J.

Int J Pharm Investig. 2013 Jan;3(1):8-14. doi: 10.4103/2230-973X.108959.

39.

Rutin : therapeutic potential and recent advances in drug delivery.

Sharma S, Ali A, Ali J, Sahni JK, Baboota S.

Expert Opin Investig Drugs. 2013 Aug;22(8):1063-79. doi: 10.1517/13543784.2013.805744. Epub 2013 Jun 25. Review.

PMID:
23795677
40.

Exploring drug delivery systems for treating osteoporosis.

Fazil M, Ali A, Baboota S, Sahni JK, Ali J.

Expert Opin Drug Deliv. 2013 Aug;10(8):1123-36. doi: 10.1517/17425247.2013.785518. Epub 2013 Mar 29. Review.

PMID:
23537096
41.

The SLC41 family of MgtE-like magnesium transporters.

Sahni J, Scharenberg AM.

Mol Aspects Med. 2013 Apr-Jun;34(2-3):620-8. doi: 10.1016/j.mam.2012.05.012. Review.

42.

Treatment modalities and evaluation models for periodontitis.

Tariq M, Iqbal Z, Ali J, Baboota S, Talegaonkar S, Ahmad Z, Sahni JK.

Int J Pharm Investig. 2012 Jul;2(3):106-22. doi: 10.4103/2230-973X.104394.

43.

Preparation, characterization, in vivo biodistribution and pharmacokinetic studies of donepezil-loaded PLGA nanoparticles for brain targeting.

Md S, Ali M, Baboota S, Sahni JK, Bhatnagar A, Ali J.

Drug Dev Ind Pharm. 2014 Feb;40(2):278-87. doi: 10.3109/03639045.2012.758130. Epub 2013 Feb 1.

PMID:
23369094
44.

Bromocriptine loaded chitosan nanoparticles intended for direct nose to brain delivery: pharmacodynamic, pharmacokinetic and scintigraphy study in mice model.

Md S, Khan RA, Mustafa G, Chuttani K, Baboota S, Sahni JK, Ali J.

Eur J Pharm Sci. 2013 Feb 14;48(3):393-405. doi: 10.1016/j.ejps.2012.12.007. Epub 2012 Dec 21.

PMID:
23266466
45.

Exploring delivery of nutraceuticals using nanotechnology.

Sahni JK.

Int J Pharm Investig. 2012 Apr;2(2):53. doi: 10.4103/2230-973X.100033. No abstract available.

46.

Computerized assessment of intraretinal and subretinal fluid regions in spectral-domain optical coherence tomography images of the retina.

Zheng Y, Sahni J, Campa C, Stangos AN, Raj A, Harding SP.

Am J Ophthalmol. 2013 Feb;155(2):277-286.e1. doi: 10.1016/j.ajo.2012.07.030. Epub 2012 Oct 27.

PMID:
23111180
47.

Adverse ophthalmic reaction in poppers users: case series of 'poppers maculopathy'.

Davies AJ, Kelly SP, Naylor SG, Bhatt PR, Mathews JP, Sahni J, Haslett R, McKibbin M.

Eye (Lond). 2012 Nov;26(11):1479-86. doi: 10.1038/eye.2012.191. Epub 2012 Oct 19.

48.

The B. subtilis MgtE magnesium transporter can functionally compensate TRPM7-deficiency in vertebrate B-cells.

Sahni J, Song Y, Scharenberg AM.

PLoS One. 2012;7(9):e44452. doi: 10.1371/journal.pone.0044452. Epub 2012 Sep 6.

49.

Nanostructured lipid carriers system: recent advances in drug delivery.

Iqbal MA, Md S, Sahni JK, Baboota S, Dang S, Ali J.

J Drug Target. 2012 Dec;20(10):813-30. doi: 10.3109/1061186X.2012.716845. Epub 2012 Aug 29. Review.

PMID:
22931500
50.

Development and validation of stability-indicating assay method by UPLC for a fixed dose combination of atorvastatin and ezetimibe.

Goel A, Baboota S, Sahni JK, Srinivas KS, Gupta RS, Gupta A, Semwal VP, Ali J.

J Chromatogr Sci. 2013 Mar;51(3):222-8. doi: 10.1093/chromsci/bms131. Epub 2012 Aug 3.

PMID:
22865836

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