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Items: 1 to 50 of 323

1.

OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation.

Schöpf B, Weissensteiner H, Schäfer G, Fazzini F, Charoentong P, Naschberger A, Rupp B, Fendt L, Bukur V, Giese I, Sorn P, Sant'Anna-Silva AC, Iglesias-Gonzalez J, Sahin U, Kronenberg F, Gnaiger E, Klocker H.

Nat Commun. 2020 Mar 20;11(1):1487. doi: 10.1038/s41467-020-15237-5.

2.

Graft-versus-cancer effect and innovative approaches in the treatment of refractory solid tumors.

Şahin U, Demirer T.

Turk J Med Sci. 2020 Mar 17. doi: 10.3906/sag-1911-112. [Epub ahead of print]

PMID:
32178508
3.

Cross-cultural adaptation and psychometric properties of the Fear of Falling Avoidance Behavior Questionnaire in Turkish community-dwelling older adults.

Acaröz Candan S, Demircioğlu A, Şahin ÜK.

Disabil Rehabil. 2020 Mar 5:1-8. doi: 10.1080/09638288.2020.1734674. [Epub ahead of print]

PMID:
32135067
4.

Targeting the tumor vasculature with engineered cystine-knot miniproteins.

Lui BG, Salomon N, Wüstehube-Lausch J, Daneschdar M, Schmoldt HU, Türeci Ö, Sahin U.

Nat Commun. 2020 Jan 15;11(1):295. doi: 10.1038/s41467-019-13948-y.

5.

An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors.

Reinhard K, Rengstl B, Oehm P, Michel K, Billmeier A, Hayduk N, Klein O, Kuna K, Ouchan Y, Wöll S, Christ E, Weber D, Suchan M, Bukur T, Birtel M, Jahndel V, Mroz K, Hobohm K, Kranz L, Diken M, Kühlcke K, Türeci Ö, Sahin U.

Science. 2020 Jan 24;367(6476):446-453. doi: 10.1126/science.aay5967. Epub 2020 Jan 2.

PMID:
31896660
6.

Assessment of the health risk related to exposure to ultrafine, fine, and total particulates and metals in a metal finishing plant.

Onat B, Çalışkan NS, Şahin ÜA, Uzun B.

Environ Sci Pollut Res Int. 2020 Feb;27(4):4058-4066. doi: 10.1007/s11356-019-06891-4. Epub 2019 Dec 10.

PMID:
31823257
7.

Excess Mortality in Istanbul during Extreme Heat Waves between 2013 and 2017.

Can G, Şahin Ü, Sayılı U, Dubé M, Kara B, Acar HC, İnan B, Aksu Sayman Ö, Lebel G, Bustinza R, Küçükali H, Güven U, Gosselin P.

Int J Environ Res Public Health. 2019 Nov 7;16(22). pii: E4348. doi: 10.3390/ijerph16224348.

8.

A Trans-amplifying RNA Vaccine Strategy for Induction of Potent Protective Immunity.

Beissert T, Perkovic M, Vogel A, Erbar S, Walzer KC, Hempel T, Brill S, Haefner E, Becker R, Türeci Ö, Sahin U.

Mol Ther. 2020 Jan 8;28(1):119-128. doi: 10.1016/j.ymthe.2019.09.009. Epub 2019 Sep 12.

PMID:
31624015
9.

Treatment adherence and short-term outcomes of smoking cessation outpatient clinic patients.

Karadoğan D, Önal Ö, Şahin DS, Kanbay Y, Alp S, Şahin Ü.

Tob Induc Dis. 2018 Aug 30;16:38. doi: 10.18332/tid/94212. eCollection 2018.

10.

Personalized Neo-Epitope Vaccines for Cancer Treatment.

Vormehr M, Diken M, Türeci Ö, Sahin U, Kreiter S.

Recent Results Cancer Res. 2020;214:153-167. doi: 10.1007/978-3-030-23765-3_5.

PMID:
31473852
11.

A molecule inducing androgen receptor degradation and selectively targeting prostate cancer cells.

Auvin S, Öztürk H, Abaci YT, Mautino G, Meyer-Losic F, Jollivet F, Bashir T, de Thé H, Sahin U.

Life Sci Alliance. 2019 Aug 20;2(4). pii: e201800213. doi: 10.26508/lsa.201800213. Print 2019 Aug.

12.

HPV16 RNA-LPX vaccine mediates complete regression of aggressively growing HPV-positive mouse tumors and establishes protective T cell memory.

Grunwitz C, Salomon N, Vascotto F, Selmi A, Bukur T, Diken M, Kreiter S, Türeci Ö, Sahin U.

Oncoimmunology. 2019 Jul 11;8(9):e1629259. doi: 10.1080/2162402X.2019.1629259. eCollection 2019.

13.

ArtiFuse-computational validation of fusion gene detection tools without relying on simulated reads.

Sorn P, Holtsträter C, Löwer M, Sahin U, Weber D.

Bioinformatics. 2020 Jan 15;36(2):373-379. doi: 10.1093/bioinformatics/btz613.

PMID:
31373612
14.

Impact of molecular subtypes on the prediction of distant recurrence in estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) negative breast cancer upon five years of endocrine therapy.

Laible M, Hartmann K, Gürtler C, Anzeneder T, Wirtz R, Weber S, Keller T, Sahin U, Rees M, Ramaswamy A.

BMC Cancer. 2019 Jul 15;19(1):694. doi: 10.1186/s12885-019-5890-z.

15.

A multicentre, phase IIa study of zolbetuximab as a single agent in patients with recurrent or refractory advanced adenocarcinoma of the stomach or lower oesophagus: the MONO study.

Türeci O, Sahin U, Schulze-Bergkamen H, Zvirbule Z, Lordick F, Koeberle D, Thuss-Patience P, Ettrich T, Arnold D, Bassermann F, Al-Batran SE, Wiechen K, Dhaene K, Maurus D, Gold M, Huber C, Krivoshik A, Arozullah A, Park JW, Schuler M.

Ann Oncol. 2019 Sep 1;30(9):1487-1495. doi: 10.1093/annonc/mdz199.

16.

Withdrawal: Identification of tumor antigens among the HLA peptidomes of glioblastoma tumors and plasma.

Shraibman B, Barnea E, Kadosh DM, Haimovich Y, Slobodin G, Rosner I, López-Larrea C, Hilf N, Kuttruff S, Song C, Britten C, Castle J, Kreiter S, Frenzel K, Tatagiba M, Tabatabai G, Dietrich PY, Dutoit V, Wick W, Platten M, Winkler F, von Deimling A, Kroep J, Sahuquillo J, Martinez-Ricarte F, Rodon J, Lassen U, Ottensmeier C, van der Burg SH, Thor Straten P, Poulsen HS, Ponsati B, Okada H, Rammensee HG, Sahin U, Singh H, Admon A.

Mol Cell Proteomics. 2019 Jun;18(6):1270. doi: 10.1074/mcp.W119.001571. No abstract available.

17.

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma.

Shraibman B, Barnea E, Kadosh DM, Haimovich Y, Slobodin G, Rosner I, López-Larrea C, Hilf N, Kuttruff S, Song C, Britten C, Castle J, Kreiter S, Frenzel K, Tatagiba M, Tabatabai G, Dietrich PY, Dutoit V, Wick W, Platten M, Winkler F, von Deimling A, Kroep J, Sahuquillo J, Martinez-Ricarte F, Rodon J, Lassen U, Ottensmeier C, van der Burg SH, Thor Straten P, Poulsen HS, Ponsati B, Okada H, Rammensee HG, Sahin U, Singh H, Admon A.

Mol Cell Proteomics. 2019 Jun;18(6):1255-1268. doi: 10.1074/mcp.RA119.001524.

PMID:
31154438
18.

Intravenous delivery of the toll-like receptor 7 agonist SC1 confers tumor control by inducing a CD8+ T cell response.

Vascotto F, Petschenka J, Walzer KC, Vormehr M, Brkic M, Strobl S, Rösemann R, Diken M, Kreiter S, Türeci Ö, Sahin U.

Oncoimmunology. 2019 Apr 19;8(7):1601480. doi: 10.1080/2162402X.2019.1601480. eCollection 2019.

PMID:
31143525
19.

A rare disease; congenital pulmonary airway malformation in an adult.

Özçelik N, Özyurt S, Yılmaz Kara B, Şahin Ü.

Tuberk Toraks. 2019 Mar;67(1):71-76. doi: 10.5578/tt.68095.

20.

Comparison of Claudin 18.2 expression in primary tumors and lymph node metastases in Japanese patients with gastric adenocarcinoma.

Rohde C, Yamaguchi R, Mukhina S, Sahin U, Itoh K, Türeci Ö.

Jpn J Clin Oncol. 2019 Sep 1;49(9):870-876. doi: 10.1093/jjco/hyz068.

21.

Challenges towards the realization of individualized cancer vaccines.

Türeci Ö, Löwer M, Schrörs B, Lang M, Tadmor A, Sahin U.

Nat Biomed Eng. 2018 Aug;2(8):566-569. doi: 10.1038/s41551-018-0266-2. No abstract available.

PMID:
31015635
22.

A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA.

Baiersdörfer M, Boros G, Muramatsu H, Mahiny A, Vlatkovic I, Sahin U, Karikó K.

Mol Ther Nucleic Acids. 2019 Apr 15;15:26-35. doi: 10.1016/j.omtn.2019.02.018. Epub 2019 Feb 27.

23.

Immunization status in chronic obstructive pulmonary disease: A multicenter study from Turkey.

Ozlu T, Bulbul Y, Aydin D, Tatar D, Kuyucu T, Erboy F, Koseoglu HI, Anar C, Sunnetcioglu A, Gulhan PY, Sahin U, Ekici A, Duru S, Ulasli SS, Kurtipek E, Gunay S; RIMPACT Study Investigators.

Ann Thorac Med. 2019 Jan-Mar;14(1):75-82. doi: 10.4103/atm.ATM_145_18.

24.

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma.

Hilf N, Kuttruff-Coqui S, Frenzel K, Bukur V, Stevanović S, Gouttefangeas C, Platten M, Tabatabai G, Dutoit V, van der Burg SH, Straten PT, Martinez-Ricarte F, Ponsati B, Okada H, Lassen U, Admon A, Ottensmeier CH, Ulges A, Kreiter S, von Deimling A, Skardelly M, Migliorini D, Kroep JR, Idorn M, Rodon J, Piro J, Poulsen HS, Shraibman B, McCann K, Mendrzyk R, Lower M, Stieglbauer M, Britten CM, Capper D, Welters MJP, Sahuquillo J, Kiesel K, Derhovanessian E, Rusch E, Bunse L, Song C, Heesch S, Wagner C, Kemmer-Bruck A, Ludwig J, Castle JC, Schoor O, Tadmor AD, Green E, Fritsche J, Meyer M, Pawlowski N, Dorner S, Hoffgaard F, Rossler B, Maurer D, Weinschenk T, Reinhardt C, Huber C, Rammensee HG, Singh-Jasuja H, Sahin U, Dietrich PY, Wick W.

Nature. 2019 Feb;566(7745):E13. doi: 10.1038/s41586-019-0959-z.

PMID:
30733620
25.

A non-functional neoepitope specific CD8+ T-cell response induced by tumor derived antigen exposure in vivo.

Vormehr M, Reinhard K, Blatnik R, Josef K, Beck JD, Salomon N, Suchan M, Selmi A, Vascotto F, Zerweck J, Wenschuh H, Diken M, Kreiter S, Türeci Ö, Riemer AB, Sahin U.

Oncoimmunology. 2018 Dec 24;8(3):1553478. doi: 10.1080/2162402X.2018.1553478. eCollection 2019.

26.

Harnessing Tumor Mutations for Truly Individualized Cancer Vaccines.

Vormehr M, Türeci Ö, Sahin U.

Annu Rev Med. 2019 Jan 27;70:395-407. doi: 10.1146/annurev-med-042617-101816. Review.

PMID:
30691374
27.

Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3' UTRs Identified by Cellular Library Screening.

Orlandini von Niessen AG, Poleganov MA, Rechner C, Plaschke A, Kranz LM, Fesser S, Diken M, Löwer M, Vallazza B, Beissert T, Bukur V, Kuhn AN, Türeci Ö, Sahin U.

Mol Ther. 2019 Apr 10;27(4):824-836. doi: 10.1016/j.ymthe.2018.12.011. Epub 2018 Dec 18.

28.

Is there a role of high dose chemotherapy and autologous stem cell transplantation in the treatment of Ewing's sarcoma and osteosarcomas?

Karadurmus N, Sahin U, Bahadir Basgoz B, Demirer T.

J BUON. 2018 Sep-Oct;23(5):1235-1241. Review.

29.

Actively personalized vaccination trial for newly diagnosed glioblastoma.

Hilf N, Kuttruff-Coqui S, Frenzel K, Bukur V, Stevanović S, Gouttefangeas C, Platten M, Tabatabai G, Dutoit V, van der Burg SH, Thor Straten P, Martínez-Ricarte F, Ponsati B, Okada H, Lassen U, Admon A, Ottensmeier CH, Ulges A, Kreiter S, von Deimling A, Skardelly M, Migliorini D, Kroep JR, Idorn M, Rodon J, Piró J, Poulsen HS, Shraibman B, McCann K, Mendrzyk R, Löwer M, Stieglbauer M, Britten CM, Capper D, Welters MJP, Sahuquillo J, Kiesel K, Derhovanessian E, Rusch E, Bunse L, Song C, Heesch S, Wagner C, Kemmer-Brück A, Ludwig J, Castle JC, Schoor O, Tadmor AD, Green E, Fritsche J, Meyer M, Pawlowski N, Dorner S, Hoffgaard F, Rössler B, Maurer D, Weinschenk T, Reinhardt C, Huber C, Rammensee HG, Singh-Jasuja H, Sahin U, Dietrich PY, Wick W.

Nature. 2019 Jan;565(7738):240-245. doi: 10.1038/s41586-018-0810-y. Epub 2018 Dec 19. Erratum in: Nature. 2019 Feb;566(7745):E13.

PMID:
30568303
30.

Efficient Induction of T Cells against Conserved HIV-1 Regions by Mosaic Vaccines Delivered as Self-Amplifying mRNA.

Moyo N, Vogel AB, Buus S, Erbar S, Wee EG, Sahin U, Hanke T.

Mol Ther Methods Clin Dev. 2018 Oct 26;12:32-46. doi: 10.1016/j.omtm.2018.10.010. eCollection 2019 Mar 15.

31.

Characterization of zolbetuximab in pancreatic cancer models.

Türeci Ӧ, Mitnacht-Kraus R, Wöll S, Yamada T, Sahin U.

Oncoimmunology. 2018 Nov 10;8(1):e1523096. doi: 10.1080/2162402X.2018.1523096. eCollection 2019.

32.

Induction of immunosuppressive functions and NF-κB by FLIP in monocytes.

Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, Sartoris S, Solito S, Mandruzzato S, Vascotto F, Hippen KL, Mondanelli G, Grohmann U, Piro G, Carbone C, Melisi D, Lawlor RT, Scarpa A, Lamolinara A, Iezzi M, Fassan M, Bicciato S, Blazar BR, Sahin U, Murray PJ, Bronte V.

Nat Commun. 2018 Dec 5;9(1):5193. doi: 10.1038/s41467-018-07654-4.

33.

Comparison of subdermal and perforator delay techniques on a rat flap model.

Altinel D, Biltekin B, Serin M, Sahin U, Altindas M.

Indian J Plast Surg. 2018 May-Aug;51(2):196-201. doi: 10.4103/ijps.IJPS_28_17.

34.

Investigation of charge ratio variation in mRNA - DEAE-dextran polyplex delivery systems.

Siewert C, Haas H, Nawroth T, Ziller A, Nogueira SS, Schroer MA, Blanchet CE, Svergun DI, Radulescu A, Bates F, Huesemann Y, Radsak MP, Sahin U, Langguth P.

Biomaterials. 2019 Feb;192:612-620. doi: 10.1016/j.biomaterials.2018.10.020. Epub 2018 Nov 17.

35.

Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue.

Hartmann K, Schlombs K, Laible M, Gürtler C, Schmidt M, Sahin U, Lehr HA.

Diagn Pathol. 2018 Oct 20;13(1):83. doi: 10.1186/s13000-018-0760-6.

36.

The large carrion beetles (Coleoptera: Silphidae) of Turkey: a review with a new species record.

ÇİftÇİ D, RŮŽiČka J, Hasbenlİ A, Şahİn Ü.

Zootaxa. 2018 Jun 28;4441(3):555-591. doi: 10.11646/zootaxa.4441.3.10.

PMID:
30314003
37.

A Review of Allogeneic Hematopoietic Stem Cell Transplantation in Metastatic Breast Cancer.

Karadurmus N, Sahin U, Bahadir Basgoz B, Arpaci F, Demirer T.

Int J Hematol Oncol Stem Cell Res. 2018 Apr 1;12(2):111-116. Review.

38.

Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans.

Fellermeier-Kopf S, Gieseke F, Sahin U, Müller D, Pfizenmaier K, Kontermann RE.

Oncoimmunology. 2018 Aug 1;7(9):e1471442. doi: 10.1080/2162402X.2018.1471442. eCollection 2018.

39.

Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma.

Kalaora S, Wolf Y, Feferman T, Barnea E, Greenstein E, Reshef D, Tirosh I, Reuben A, Patkar S, Levy R, Quinkhardt J, Omokoko T, Qutob N, Golani O, Zhang J, Mao X, Song X, Bernatchez C, Haymaker C, Forget MA, Creasy C, Greenberg P, Carter BW, Cooper ZA, Rosenberg SA, Lotem M, Sahin U, Shakhar G, Ruppin E, Wargo JA, Friedman N, Admon A, Samuels Y.

Cancer Discov. 2018 Nov;8(11):1366-1375. doi: 10.1158/2159-8290.CD-17-1418. Epub 2018 Sep 12.

40.

Studying Tumor-ReacTive T Cells: A Personalized Organoid Model.

Sahin U.

Cell Stem Cell. 2018 Sep 6;23(3):318-319. doi: 10.1016/j.stem.2018.08.015.

41.

An RNA toolbox for cancer immunotherapy.

Pastor F, Berraondo P, Etxeberria I, Frederick J, Sahin U, Gilboa E, Melero I.

Nat Rev Drug Discov. 2018 Oct;17(10):751-767. doi: 10.1038/nrd.2018.132. Epub 2018 Sep 7. Review.

PMID:
30190565
42.

In vivo imaging of the immune response upon systemic RNA cancer vaccination by FDG-PET.

Pektor S, Hilscher L, Walzer KC, Miederer I, Bausbacher N, Loquai C, Schreckenberger M, Sahin U, Diken M, Miederer M.

EJNMMI Res. 2018 Aug 15;8(1):80. doi: 10.1186/s13550-018-0435-z.

43.

Factors Affecting Influenza Vaccination Rates among Patients with Chronic Obstructive Pulmonary Disease in Rize, Turkey.

Özyurt S, Kara BY, Özçelik N, Şahin Ü.

Turk Thorac J. 2018 Jul;19(3):122-126. doi: 10.5152/TurkThoracJ.2018.17075. Epub 2018 Jun 12.

44.

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma.

Shraibman B, Barnea E, Kadosh DM, Haimovich Y, Slobodin G, Rosner I, López-Larrea C, Hilf N, Kuttruff S, Song C, Britten C, Castle J, Kreiter S, Frenzel K, Tatagiba M, Tabatabai G, Dietrich PY, Dutoit V, Wick W, Platten M, Winkler F, von Deimling A, Kroep J, Sahuquillo J, Martinez-Ricarte F, Rodon J, Lassen U, Ottensmeier C, van der Burg SH, Thor Straten P, Poulsen HS, Ponsati B, Okada H, Rammensee HG, Sahin U, Singh H, Admon A.

Mol Cell Proteomics. 2018 Nov;17(11):2132-2145. doi: 10.1074/mcp.RA118.000792. Epub 2018 Aug 2. Retraction in: Mol Cell Proteomics. 2019 Jun;18(6):1270.

45.

Monitoring Translation Activity of mRNA-Loaded Nanoparticles in Mice.

Rosigkeit S, Meng M, Grunwitz C, Gomes P, Kreft A, Hayduk N, Heck R, Pickert G, Ziegler K, Abassi Y, Röder J, Kaps L, Vascotto F, Beissert T, Witzel S, Kuhn A, Diken M, Schuppan D, Sahin U, Haas H, Bockamp E.

Mol Pharm. 2018 Sep 4;15(9):3909-3919. doi: 10.1021/acs.molpharmaceut.8b00370. Epub 2018 Aug 9.

PMID:
30028629
46.

A phase I dose-escalation study of IMAB362 (Zolbetuximab) in patients with advanced gastric and gastro-oesophageal junction cancer.

Sahin U, Schuler M, Richly H, Bauer S, Krilova A, Dechow T, Jerling M, Utsch M, Rohde C, Dhaene K, Huber C, Türeci Ö.

Eur J Cancer. 2018 Sep;100:17-26. doi: 10.1016/j.ejca.2018.05.007. Epub 2018 Jun 21.

47.

In Silico Typing of Classical and Non-classical HLA Alleles from Standard RNA-Seq Reads.

Boegel S, Bukur T, Castle JC, Sahin U.

Methods Mol Biol. 2018;1802:177-191. doi: 10.1007/978-1-4939-8546-3_12.

PMID:
29858809
48.

Water Oxidation Electrocatalysis with a Cobalt-Borate-Based Hybrid System under Neutral Conditions.

Turhan EA, Nune SVK, Ülker E, Şahin U, Dede Y, Karadas F.

Chemistry. 2018 Jul 20;24(41):10372-10382. doi: 10.1002/chem.201801412. Epub 2018 Jul 5.

PMID:
29775244
49.

Development of an RNA-based kit for easy generation of TCR-engineered lymphocytes to control T-cell assay performance.

Bidmon N, Kind S, Welters MJP, Joseph-Pietras D, Laske K, Maurer D, Hadrup SR, Schreibelt G, Rae R, Sahin U, Gouttefangeas C, Britten CM, van der Burg SH.

J Immunol Methods. 2018 Jul;458:74-82. doi: 10.1016/j.jim.2018.04.007. Epub 2018 Apr 21.

50.

Multiple Arterial Thrombosis Related with Cantharidin Ingestion.

Narli Ozdemir Z, Sahin U, Civriz Bozdag S, Ilhan O.

Case Rep Hematol. 2018 Feb 19;2018:8159093. doi: 10.1155/2018/8159093. eCollection 2018.

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