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Stereotactic Body Radiotherapy for Non-Spine Bone Metastases: A Synthesis of International Practice Patterns to Guide Treatment Planning.

Nguyen TK, Sahgal A, Dagan R, Eppinga W, Guckenberger M, Kim JH, Lo SS, Redmond KJ, Siva S, Stish BJ, Tseng CL.

Pract Radiat Oncol. 2020 Mar 11. pii: S1879-8500(20)30056-4. doi: 10.1016/j.prro.2020.02.011. [Epub ahead of print]


Impact of Systemic Therapy in Metastatic Renal-Cell Carcinoma Patients With Synchronous and Metachronous Brain Metastases.

Parmar A, Soliman H, Sahgal A, Bjarnason GA.

Clin Genitourin Cancer. 2019 Nov 6. pii: S1558-7673(19)30328-3. doi: 10.1016/j.clgc.2019.10.024. [Epub ahead of print]


Single fraction radiosurgery, fractionated radiosurgery, and conventional radiotherapy for spinal oligometastasis (SAFFRON): A systematic review and meta-analysis.

Singh R, Lehrer EJ, Dahshan B, Palmer JD, Sahgal A, Gerszten PC, Zaorsky NG, Trifiletti DM.

Radiother Oncol. 2020 Feb 27;146:76-89. doi: 10.1016/j.radonc.2020.01.030. [Epub ahead of print] Review.


Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today.

Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP.

Int J Radiat Oncol Biol Phys. 2020 Feb 19. pii: S0360-3016(20)30205-4. doi: 10.1016/j.ijrobp.2020.01.051. [Epub ahead of print]


Current approaches to the management of brain metastases.

Suh JH, Kotecha R, Chao ST, Ahluwalia MS, Sahgal A, Chang EL.

Nat Rev Clin Oncol. 2020 Feb 20. doi: 10.1038/s41571-019-0320-3. [Epub ahead of print] Review.


Stereotactic Radiosurgery for Spetzler-Martin Grade I and II Arteriovenous Malformations: International Society of Stereotactic Radiosurgery (ISRS) Practice Guideline.

Graffeo CS, Sahgal A, De Salles A, Fariselli L, Levivier M, Ma L, Paddick I, Regis JM, Sheehan J, Suh J, Yomo S, Pollock BE.

Neurosurgery. 2020 Feb 17. pii: nyaa004. doi: 10.1093/neuros/nyaa004. [Epub ahead of print]


Technical Principles of Dual-Energy Cone Beam Computed Tomography and Clinical Applications for Radiation Therapy.

Sajja S, Lee Y, Eriksson M, Nordström H, Sahgal A, Hashemi M, Mainprize JG, Ruschin M.

Adv Radiat Oncol. 2019 Jul 30;5(1):1-16. doi: 10.1016/j.adro.2019.07.013. eCollection 2020 Jan-Feb. Review.


Estrogen, Progesterone and HER2 Receptor Discordance Between Primary Tumor and Brain Metastases in Breast Cancer and Its Effect on Treatment and Survival.

Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP.

Neuro Oncol. 2020 Feb 8. pii: noaa025. doi: 10.1093/neuonc/noaa025. [Epub ahead of print]


In Regard to Susko et al.

Soliman H, Lo SS, Sahgal A.

Int J Radiat Oncol Biol Phys. 2020 Mar 1;106(3):648-649. doi: 10.1016/j.ijrobp.2019.11.405. No abstract available.


Surgical or Radiation Therapy for the Treatment of Cervical Spine Metastases: Results From the Epidemiology, Process, and Outcomes of Spine Oncology (EPOSO) Cohort.

Bond MR, Versteeg AL, Sahgal A, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Fehlings MG, Lazary A, Clarke MJ, Boriani S, Bettegowda C, Arnold PM, Gokaslan ZL, Fisher CG.

Global Spine J. 2020 Feb;10(1):21-29. doi: 10.1177/2192568219839407. Epub 2019 Mar 31.


Survey of current practices from an international task force for gynecological stereotactic ablative radiotherapy.

Leung E, Gladwish A, Sahgal A, Lo SS, Kunos CA, Lanciano RM, Mantz CA, Guckenberger M, Zagar TM, Mayr NA, Chang AR, Jorcano S, Biswas T, Pontoriero A, Albuquerque KV.

Radiat Oncol. 2020 Jan 30;15(1):24. doi: 10.1186/s13014-020-1469-8.


Stereotactic body radiotherapy for benign spinal tumors: Meningiomas, schwannomas, and neurofibromas.

Hwang L, Okoye CC, Patel RB, Sahgal A, Foote M, Redmond KJ, Hofstetter C, Saigal R, Mossa-Basha M, Yuh W, Mayr NA, Chao ST, Chang EL, Lo SS.

J Radiosurg SBRT. 2019;6(3):167-177. Review.


Use of Radiomics for the Prediction of Local Control of Brain Metastases After Stereotactic Radiosurgery.

Mouraviev A, Detsky J, Sahgal A, Ruschin M, Lee YK, Karam I, Heyn C, Stanisz GJ, Martel AL.

Neuro Oncol. 2020 Jan 20. pii: noaa007. doi: 10.1093/neuonc/noaa007. [Epub ahead of print]


Experimental measurement of ionization chamber angular response and associated magnetic field correction factors in MR-linac.

Iakovenko V, Keller B, Sahgal A, Sarfehnia A.

Med Phys. 2020 Jan 18. doi: 10.1002/mp.14025. [Epub ahead of print]


An MR Radiomics Framework for Predicting the Outcome of Stereotactic Radiation Therapy in Brain Metastasis.

Karami E, Ruschin M, Soliman H, Sahgal A, Stanisz GJ, Sadeghi-Naini A.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:1022-1025. doi: 10.1109/EMBC.2019.8856558.


An Automatic Framework for Segmentation of Brain Tumours at Follow-up Scans after Radiation Therapy.

Karami E, Jalalifar A, Ruschin M, Soliman H, Sahgal A, Stanisz GJ, Sadeghi-Naini A.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:463-466. doi: 10.1109/EMBC.2019.8856858.


Adverse Radiation Effect After Hypofractionated Stereotactic Radiosurgery in 5 Daily Fractions for Surgical Cavities and Intact Brain Metastases.

Faruqi S, Ruschin M, Soliman H, Myrehaug S, Zeng KL, Husain Z, Atenafu E, Tseng CL, Das S, Perry J, Maralani P, Heyn C, Mainprize T, Sahgal A.

Int J Radiat Oncol Biol Phys. 2020 Mar 15;106(4):772-779. doi: 10.1016/j.ijrobp.2019.12.002. Epub 2020 Jan 9.


Quantitative MRI Biomarkers of Stereotactic Radiotherapy Outcome in Brain Metastasis.

Karami E, Soliman H, Ruschin M, Sahgal A, Myrehaug S, Tseng CL, Czarnota GJ, Jabehdar-Maralani P, Chugh B, Lau A, Stanisz GJ, Sadeghi-Naini A.

Sci Rep. 2019 Dec 27;9(1):19830. doi: 10.1038/s41598-019-56185-5.


International consensus recommendations for target volume delineation specific to sacral metastases and spinal stereotactic body radiation therapy (SBRT).

Dunne EM, Sahgal A, Lo SS, Bergman A, Kosztyla R, Dea N, Chang EL, Chang UK, Chao ST, Faruqi S, Ghia AJ, Redmond KJ, Soltys SG, Liu MC.

Radiother Oncol. 2019 Dec 21;145:21-29. doi: 10.1016/j.radonc.2019.11.026. [Epub ahead of print]


Surface and near-surface dose measurements at beam entry and exit in a 1.5 T MR-Linac using optically stimulated luminescence dosimeters.

Kim A, Lim-Reinders S, Ahmad SB, Sahgal A, Keller BM.

Phys Med Biol. 2020 Feb 12;65(4):045012. doi: 10.1088/1361-6560/ab64b6.


Stereotactic radiosurgery for non-functioning pituitary adenomas: meta-analysis and International Stereotactic Radiosurgery Society practice opinion.

Kotecha R, Sahgal A, Rubens M, De Salles A, Fariselli L, Pollock BE, Levivier M, Ma L, Paddick I, Regis J, Sheehan J, Yomo S, Suh JH.

Neuro Oncol. 2020 Mar 5;22(3):318-332. doi: 10.1093/neuonc/noz225.


A Cancer Care Ontario Organizational Guideline for the Delivery of Stereotactic Radiosurgery for Brain Metastasis in Ontario, Canada.

Sahgal A, Kellett S, Ruschin M, Greenspoon J, Follwell M, Sinclair J, Islam O, Perry J; Stereotactic Radiosurgery for Brain Metastasis Guideline Development Group.

Pract Radiat Oncol. 2019 Nov 26. pii: S1879-8500(19)30329-7. doi: 10.1016/j.prro.2019.11.002. [Epub ahead of print] Review.


Metastatic Spine Disease: Should Patients With Short Life Expectancy Be Denied Surgical Care? An International Retrospective Cohort Study.

Dea N, Versteeg AL, Sahgal A, Verlaan JJ, Charest-Morin R, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Lazary A, Fehlings MG, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Laufer I, Gokaslan ZL, Fisher CG.

Neurosurgery. 2019 Nov 6. pii: nyz472. doi: 10.1093/neuros/nyz472. [Epub ahead of print]


Progression-Free but No Overall Survival Benefit for Adult Patients with Bevacizumab Therapy for the Treatment of Newly Diagnosed Glioblastoma: A Systematic Review and Meta-Analysis.

Kaka N, Hafazalla K, Samawi H, Simpkin A, Perry J, Sahgal A, Das S.

Cancers (Basel). 2019 Nov 4;11(11). pii: E1723. doi: 10.3390/cancers11111723. Review.


Improved dosimetric accuracy with semi-automatic contour propagation of organs-at-risk in glioblastoma patients undergoing chemoradiation.

Lee S, Stewart J, Lee Y, Myrehaug S, Sahgal A, Ruschin M, Tseng CL.

J Appl Clin Med Phys. 2019 Dec;20(12):45-53. doi: 10.1002/acm2.12758. Epub 2019 Oct 31.


Real-Time Infrared Motion Tracking Analysis for Patients Treated With Gated Frameless Image Guided Stereotactic Radiosurgery.

MacDonald RL, Lee Y, Schasfoort J, Soliman H, Sahgal A, Ruschin M.

Int J Radiat Oncol Biol Phys. 2020 Feb 1;106(2):413-421. doi: 10.1016/j.ijrobp.2019.10.030. Epub 2019 Oct 23.


The transformation of radiation oncology using real-time magnetic resonance guidance: A review.

Hall WA, Paulson ES, van der Heide UA, Fuller CD, Raaymakers BW, Lagendijk JJW, Li XA, Jaffray DA, Dawson LA, Erickson B, Verheij M, Harrington KJ, Sahgal A, Lee P, Parikh PJ, Bassetti MF, Robinson CG, Minsky BD, Choudhury A, Tersteeg RJHA, Schultz CJ; MR Linac Atlantic Consortium and the ViewRay C2T2 Research Consortium.

Eur J Cancer. 2019 Nov;122:42-52. doi: 10.1016/j.ejca.2019.07.021. Epub 2019 Oct 12. Review.


Spinal Cord Dose Tolerance to Stereotactic Body Radiation Therapy.

Sahgal A, Chang JH, Ma L, Marks LB, Milano MT, Medin P, Niemierko A, Soltys SG, Tomé WA, Wong CS, Yorke E, Grimm J, Jackson A.

Int J Radiat Oncol Biol Phys. 2019 Oct 10. pii: S0360-3016(19)33862-3. doi: 10.1016/j.ijrobp.2019.09.038. [Epub ahead of print]


Editorial: Contemporary Management of Intracranial Metastatic Disease.

Das S, Sahgal A.

Front Oncol. 2019 Aug 28;9:818. doi: 10.3389/fonc.2019.00818. eCollection 2019. No abstract available.


Outcomes of extra-cranial stereotactic body radiotherapy for metastatic colorectal cancer: Dose and site of metastases matter.

Thompson R, Cheung P, Chu W, Myrehaug S, Poon I, Sahgal A, Soliman H, Tseng CL, Wong S, Ung Y, Beatriz Kinupe Abrahão A, Erler D, Zhang L, Ko YJ, Chung HT.

Radiother Oncol. 2020 Jan;142:236-245. doi: 10.1016/j.radonc.2019.08.018. Epub 2019 Sep 19.


Postoperative Stereotactic Body Radiotherapy for Spinal Metastases and the Impact of Epidural Disease Grade.

Alghamdi M, Sahgal A, Soliman H, Myrehaug S, Yang VXD, Das S, Wilson J, Campbell M, Lee YK, Cawricz M, Da Costa L, Atenafu EG, Tseng CL.

Neurosurgery. 2019 Dec 1;85(6):E1111-E1118. doi: 10.1093/neuros/nyz349.


Patient satisfaction with treatment outcomes after surgery and/or radiotherapy for spinal metastases.

Versteeg AL, Sahgal A, Kawahara N, Rhines LD, Sciubba DM, Weber MH, Lazary Á, Fehlings MG, Schuster JM, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Gokaslan ZL, Fisher CG; AOSpine Knowledge Forum Tumor.

Cancer. 2019 Dec 1;125(23):4269-4277. doi: 10.1002/cncr.32465. Epub 2019 Sep 6.


Incidence of Brain Metastases in Nonmetastatic and Metastatic Breast Cancer: Is There a Role for Screening?

Komorowski AS, Warner E, MacKay HJ, Sahgal A, Pritchard KI, Jerzak KJ.

Clin Breast Cancer. 2020 Feb;20(1):e54-e64. doi: 10.1016/j.clbc.2019.06.007. Epub 2019 Jul 11.


Predictors of leptomeningeal disease following hypofractionated stereotactic radiotherapy for intact and resected brain metastases.

Nguyen TK, Sahgal A, Detsky J, Atenafu EG, Myrehaug S, Tseng CL, Husain Z, Heyn C, Maralani P, Ruschin M, Perry J, Soliman H.

Neuro Oncol. 2020 Jan 11;22(1):84-93. doi: 10.1093/neuonc/noz144.


Association of neurologic deficits with surgical outcomes and health-related quality of life after treatment for metastatic epidural spinal cord compression.

Barzilai O, Versteeg AL, Goodwin CR, Sahgal A, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Lazary A, Fehlings MG, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Gokaslan ZL, Fisher CG, Laufer I; AOSpine Knowledge Forum Tumor.

Cancer. 2019 Dec 1;125(23):4224-4231. doi: 10.1002/cncr.32420. Epub 2019 Aug 13.


Dosimetric comparison of two treatment planning systems for spine SBRT.

Lee YK, Munawar I, Mashouf S, Sahgal A, Ruschin M.

Med Dosim. 2020 Spring;45(1):77-84. doi: 10.1016/j.meddos.2019.07.001. Epub 2019 Aug 1.


Estimating survival in patients with gastrointestinal cancers and brain metastases: An update of the graded prognostic assessment for gastrointestinal cancers (GI-GPA).

Sperduto PW, Fang P, Li J, Breen W, Brown PD, Cagney D, Aizer A, Yu JB, Chiang V, Jain S, Gaspar LE, Myrehaug S, Sahgal A, Braunstein S, Sneed P, Cameron B, Attia A, Molitoris J, Wu CC, Wang TJC, Lockney NA, Beal K, Parkhurst J, Buatti JM, Shanley R, Lou E, Tandberg DD, Kirkpatrick JP, Shi D, Shih HA, Chuong M, Saito H, Aoyama H, Masucci L, Roberge D, Mehta MP.

Clin Transl Radiat Oncol. 2019 Jun 27;18:39-45. doi: 10.1016/j.ctro.2019.06.007. eCollection 2019 Sep.


Spinal metastasis: diagnosis, management and follow-up.

Mossa-Basha M, Gerszten PC, Myrehaug S, Mayr NA, Yuh WT, Jabehdar Maralani P, Sahgal A, Lo SS.

Br J Radiol. 2019 Nov;92(1103):20190211. doi: 10.1259/bjr.20190211. Epub 2019 Jul 25.


Changes in Volume and Density Parameters Measured on Computed Tomography Images Following Stereotactic Body Radiation Therapy of Nonspine Bone Metastases.

Finkelstein S, Raman S, Van Der Velden J, Zhang L, Tan C, Dhillon A, Tonolete F, Chiu N, Probyn L, McDonald R, Sahgal A, Chow E, Chin L.

Technol Cancer Res Treat. 2019 Jan 1;18:1533033819853532. doi: 10.1177/1533033819853532.


Clinical presentation, management and outcomes of sacral metastases: a multicenter, retrospective cohort study.

Charest-Morin R, Fisher CG, Versteeg AL, Sahgal A, Varga PP, Sciubba DM, Schuster JM, Weber MH, Clarke MJ, Rhines LD, Boriani S, Bettegowda C, Fehlings MG, Arnold PM, Gokaslan ZL, Dea N.

Ann Transl Med. 2019 May;7(10):214. doi: 10.21037/atm.2019.04.88.


Single-Fraction Stereotactic Radiosurgery Versus Hippocampal-Avoidance Whole Brain Radiation Therapy for Patients With 10 to 30 Brain Metastases: A Dosimetric Analysis.

Nguyen TK, Sahgal A, Detsky J, Soliman H, Myrehaug S, Tseng CL, Husain ZA, Carty A, Das S, Yang V, Lee Y, Sarfehnia A, Chugh BP, Yeboah C, Ruschin M.

Int J Radiat Oncol Biol Phys. 2019 Oct 1;105(2):394-399. doi: 10.1016/j.ijrobp.2019.06.2543. Epub 2019 Jul 5.


Photodynamic Therapy for the Treatment of Vertebral Metastases: A Phase I Clinical Trial.

Fisher C, Ali Z, Detsky J, Sahgal A, David E, Kunz M, Akens M, Chow E, Whyne C, Burch S, Wilson BC, Yee A.

Clin Cancer Res. 2019 Oct 1;25(19):5766-5776. doi: 10.1158/1078-0432.CCR-19-0673. Epub 2019 Jul 2.


Strategies to Mitigate Toxicities From Stereotactic Body Radiation Therapy for Spine Metastases.

Schaub SK, Tseng YD, Chang EL, Sahgal A, Saigal R, Hofstetter CP, Foote M, Ko AL, Yuh WTC, Mossa-Basha M, Mayr NA, Lo SS.

Neurosurgery. 2019 Dec 1;85(6):729-740. doi: 10.1093/neuros/nyz213.


Tissue segmentation-based electron density mapping for MR-only radiotherapy treatment planning of brain using conventional T1-weighted MR images.

Yu H, Oliver M, Leszczynski K, Lee Y, Karam I, Sahgal A.

J Appl Clin Med Phys. 2019 Aug;20(8):11-20. doi: 10.1002/acm2.12654. Epub 2019 Jul 1.


Quantification of pulsed saturation transfer at 1.5T and 3T.

Chan RW, Myrehaug S, Stanisz GJ, Sahgal A, Lau AZ.

Magn Reson Med. 2019 Nov;82(5):1684-1699. doi: 10.1002/mrm.27856. Epub 2019 Jun 22.


Advanced Magnetic Resonance Imaging Techniques in Management of Brain Metastases.

Mehrabian H, Detsky J, Soliman H, Sahgal A, Stanisz GJ.

Front Oncol. 2019 Jun 4;9:440. doi: 10.3389/fonc.2019.00440. eCollection 2019. Review.


Image-Guided, Linac-Based, Surgical Cavity-Hypofractionated Stereotactic Radiotherapy in 5 Daily Fractions for Brain Metastases.

Soliman H, Myrehaug S, Tseng CL, Ruschin M, Hashmi A, Mainprize T, Spears J, Das S, Yang V, da Costa L, Maralani P, Heyn C, Atenafu EG, Sahgal A.

Neurosurgery. 2019 Nov 1;85(5):E860-E869. doi: 10.1093/neuros/nyz162.


Essential Concepts for the Management of Metastatic Spine Disease: What the Surgeon Should Know and Practice.

Barzilai O, Boriani S, Fisher CG, Sahgal A, Verlaan JJ, Gokaslan ZL, Lazary A, Bettegowda C, Rhines LD, Laufer I.

Global Spine J. 2019 May;9(1 Suppl):98S-107S. doi: 10.1177/2192568219830323. Epub 2019 May 8.


Primary Bone Tumor of the Spine-An Evolving Field: What a General Spine Surgeon Should Know.

Charest-Morin R, Fisher CG, Sahgal A, Boriani S, Gokaslan ZL, Lazary A, Reynolds J, Bettegowda C, Rhines LD, Dea N.

Global Spine J. 2019 May;9(1 Suppl):108S-116S. doi: 10.1177/2192568219828727. Epub 2019 May 8.

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