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Items: 1 to 50 of 133

1.

Preparation of hybrid porcine thymus containing non-human primate thymic epithelial cells in miniature swine.

Sekijima M, Sahara H, Shimizu A, Iwanaga T, Murokawa T, Ariyoshi Y, Pomposelli T, Khosravi Maharlooei M, Sykes M, Yamada K.

Xenotransplantation. 2019 Jul 10:e12543. doi: 10.1111/xen.12543. [Epub ahead of print]

PMID:
31293016
2.

The Protective Effects of Carbon Monoxide Against Hepatic Warm Ischemia-Reperfusion Injury in MHC-Inbred Miniature Swine.

Murokawa T, Sahara H, Sekijima M, Pomposelli T, Iwanaga T, Ichinari Y, Shimizu A, Yamada K.

J Gastrointest Surg. 2019 Jun 26. doi: 10.1007/s11605-019-04283-0. [Epub ahead of print]

PMID:
31243716
3.

Calorimetric Study of Micelle Formation of Alkylammonium Chlorides in Water.

Sahara H, Harada S.

J Oleo Sci. 2018;67(11):1417-1424. doi: 10.5650/jos.ess18007.

4.

Angiogenesis-related gene expression profile in clinical cases of canine cancer.

Tanabe A, Kobayashi D, Maeda K, Taguchi M, Sahara H.

Vet Med Sci. 2019 Feb;5(1):19-29. doi: 10.1002/vms3.127. Epub 2018 Sep 28.

5.

Distribution and metabolism of 14C-sulfoquinovosylacylpropanediol (14C-SQAP) after a single intravenous administration in tumor-bearing mice.

Ruike T, Kanai Y, Iwabata K, Matsumoto Y, Murata H, Ishima M, Ohta K, Oshige M, Katsura S, Kuramochi K, Kamisuki S, Sahara H, Miura M, Sugawara F, Sakaguchi K.

Xenobiotica. 2019 Mar;49(3):346-362. doi: 10.1080/00498254.2018.1448949. Epub 2018 Apr 24.

PMID:
29543539
6.

GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels.

Watanabe H, Sahara H, Nomura S, Tanabe T, Ekanayake-Alper DK, Boyd LK, Louras NJ, Asfour A, Danton MA, Ho SH, Arn SJ, Hawley RJ, Shimizu A, Nagayasu T, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K.

Xenotransplantation. 2018 Sep;25(5):e12391. doi: 10.1111/xen.12391. Epub 2018 Mar 12.

PMID:
29527745
7.

Hydrogen sulfide prevents renal ischemia-reperfusion injury in CLAWN miniature swine.

Sekijima M, Sahara H, Miki K, Villani V, Ariyoshi Y, Iwanaga T, Tomita Y, Yamada K.

J Surg Res. 2017 Nov;219:165-172. doi: 10.1016/j.jss.2017.05.123. Epub 2017 Jun 28.

PMID:
29078877
8.

Effects of carbon monoxide on early dysfunction and microangiopathy following GalT-KO porcine pulmonary xenotransplantation in cynomolgus monkeys.

Sahara H, Sekijima M, Ariyoshi Y, Kawai A, Miura K, Waki S, Nathan L, Tomita Y, Iwanaga T, Nakano K, Matsunari H, Date H, Nagashima H, Shimizu A, Yamada K.

Xenotransplantation. 2018 Jan;25(1). doi: 10.1111/xen.12359. Epub 2017 Oct 25.

PMID:
29067747
9.

Lung xenotransplantation.

Sahara H, Watanabe H, Pomposelli T, Yamada K.

Curr Opin Organ Transplant. 2017 Dec;22(6):541-548. doi: 10.1097/MOT.0000000000000465. Review.

10.

Role of Intrinsic (Graft) Versus Extrinsic (Host) Factors in the Growth of Transplanted Organs Following Allogeneic and Xenogeneic Transplantation.

Tanabe T, Watanabe H, Shah JA, Sahara H, Shimizu A, Nomura S, Asfour A, Danton M, Boyd L, Dardenne Meyers A, Ekanayake-Alper DK, Sachs DH, Yamada K.

Am J Transplant. 2017 Jul;17(7):1778-1790. doi: 10.1111/ajt.14210. Epub 2017 Mar 3.

11.
12.

Development of the Intestinal Transplantation Model With Major Histocompatibility Complex Inbred CLAWN Miniature Swine.

Miura K, Sahara H, Waki S, Kawai A, Sekijima M, Kobayashi T, Zhang Z, Wakai T, Shimizu A, Yamada K.

Transplant Proc. 2016 May;48(4):1315-9. doi: 10.1016/j.transproceed.2016.01.023.

PMID:
27320612
13.

RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1α mRNA is translated.

Tanabe A, Tanikawa K, Tsunetomi M, Takai K, Ikeda H, Konno J, Torigoe T, Maeda H, Kutomi G, Okita K, Mori M, Sahara H.

Cancer Lett. 2016 Jun 28;376(1):34-42. doi: 10.1016/j.canlet.2016.02.022. Epub 2016 Mar 17.

PMID:
26996300
14.

Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity.

Izaguirre-Carbonell J, Kawakubo H, Murata H, Tanabe A, Takeuchi T, Kusayanagi T, Tsukuda S, Hirakawa T, Iwabata K, Kanai Y, Ohta K, Miura M, Sakaguchi K, Matsunaga S, Sahara H, Kamisuki S, Sugawara F.

Sci Rep. 2015 Oct 12;5:15136. doi: 10.1038/srep15136.

15.

Combination of Cilostazol and L-Carnitine Improves Walking Performance in Peripheral Arterial Disease Model Rats.

Shiga T, Sahara H, Orito K.

Pharmacology. 2015;96(5-6):210-6. doi: 10.1159/000439090. Epub 2015 Sep 1.

PMID:
26329263
16.

Results of life-supporting galactosyltransferase knockout kidneys in cynomolgus monkeys using two different sources of galactosyltransferase knockout Swine.

Sekijima M, Waki S, Sahara H, Tasaki M, Wilkinson RA, Villani V, Shimatsu Y, Nakano K, Matsunari H, Nagashima H, Fishman JA, Shimizu A, Yamada K.

Transplantation. 2014 Aug 27;98(4):419-26. doi: 10.1097/TP.0000000000000314.

17.

EpsinR, a target for pyrenocine B, role in endogenous MHC-II-restricted antigen presentation.

Shishido T, Hachisuka M, Ryuzaki K, Miura Y, Tanabe A, Tamura Y, Kusayanagi T, Takeuchi T, Kamisuki S, Sugawara F, Sahara H.

Eur J Immunol. 2014 Nov;44(11):3220-31. doi: 10.1002/eji.201444475. Epub 2014 Oct 30.

18.

Protective effect of neutralization of the extracellular high-mobility group box 1 on renal ischemia-reperfusion injury in miniature swine.

Miura K, Sahara H, Sekijima M, Kawai A, Waki S, Nishimura H, Setoyama K, Clayman ES, Shimizu A, Yamada K.

Transplantation. 2014 Nov 15;98(9):937-43. doi: 10.1097/TP.0000000000000358.

PMID:
25136847
19.

Radioresistance of cancer stem-like cell derived from canine tumours.

Tanabe A, Deguchi T, Sato T, Nemoto Y, Maruo T, Madarame H, Shida T, Naya Y, Ogihara K, Sahara H.

Vet Comp Oncol. 2016 Sep;14(3):e93-e101. doi: 10.1111/vco.12110. Epub 2014 Jul 28.

PMID:
25070729
20.

Canine Orientia tsutsugamushi infection: report of a case and its epidemicity.

Namikawa K, Tanabe A, Satake S, Enishi H, Kusaka H, Ide N, Neo S, Lynch J, Orito K, Morita T, Sahara H.

Southeast Asian J Trop Med Public Health. 2014 Mar;45(2):395-401.

PMID:
24968681
21.
22.

Transcriptional machinery of TNF-α-inducible YTH domain containing 2 (YTHDC2) gene.

Tanabe A, Konno J, Tanikawa K, Sahara H.

Gene. 2014 Feb 1;535(1):24-32. doi: 10.1016/j.gene.2013.11.005. Epub 2013 Nov 21.

PMID:
24269672
23.

Production of cloned NIBS (Nippon Institute for Biological Science) and α-1, 3-galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogates.

Shimatsu Y, Yamada K, Horii W, Hirakata A, Sakamoto Y, Waki S, Sano J, Saitoh T, Sahara H, Shimizu A, Yazawa H, Sachs DH, Nunoya T.

Xenotransplantation. 2013 May-Jun;20(3):157-64. doi: 10.1111/xen.12031. Epub 2013 Apr 14.

24.
25.

Booster effect of canine distemper, canine parvovirus infection and infectious canine hepatitis combination vaccine in domesticated adult dogs.

Taguchi M, Namikawa K, Maruo T, Orito K, Lynch J, Tsuchiya R, Sahara H.

Microbiol Immunol. 2012 Aug;56(8):579-82. doi: 10.1111/j.1348-0421.2012.00475.x.

26.

Anti-angiogenesis effect of 3'-sulfoquinovosyl-1'-monoacylglycerol via upregulation of thrombospondin 1.

Matsuki K, Tanabe A, Hongo A, Sugawara F, Sakaguchi K, Takahashi N, Sato N, Sahara H.

Cancer Sci. 2012 Aug;103(8):1546-52. doi: 10.1111/j.1349-7006.2012.02333.x. Epub 2012 Jun 20.

27.

Role of regional medical associations in large-scale disasters.

Sahara H.

Japan Med Assoc J. 2012 May;55(3):273-6. No abstract available.

PMID:
25237232
28.

Antibody titers for canine parvovirus type-2, canine distemper virus, and canine adenovirus type-1 in adult household dogs.

Taguchi M, Namikawa K, Maruo T, Orito K, Lynch J, Sahara H.

Can Vet J. 2011 Sep;52(9):983-6.

29.

Hepatocyte growth factor sustains T regulatory cells and prolongs the survival of kidney allografts in major histocompatibility complex-inbred CLAWN-miniature swine.

Oku M, Okumi M, Shimizu A, Sahara H, Setoyama K, Nishimura H, Sada M, Scalea J, Ido A, Sachs DH, Tsubouchi H, Yamada K.

Transplantation. 2012 Jan 27;93(2):148-55. doi: 10.1097/TP.0b013e31823be83f.

PMID:
22158517
30.

Caudal vascular hamartoma accompanied by aberrant arteriovenous structures in a dog.

Yasuno K, Kobayashi R, Ohmuro T, Kamiie J, Sahara H, Shirota K.

J Vet Diagn Invest. 2011 Sep;23(5):1051-5. doi: 10.1177/1040638711416852. Epub 2011 Aug 19.

PMID:
21908374
31.

Mammary adenoma with sebaceous differentiation in a dog.

Yasuno K, Takagi Y, Kobayashi R, Ohmuro T, Kamiie J, Sahara H, Shirota K.

J Vet Diagn Invest. 2011 Jul;23(4):832-5. doi: 10.1177/1040638711406973.

PMID:
21908334
32.

Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B.

Morohashi K, Sahara H, Watashi K, Iwabata K, Sunoki T, Kuramochi K, Takakusagi K, Miyashita H, Sato N, Tanabe A, Shimotohno K, Kobayashi S, Sakaguchi K, Sugawara F.

PLoS One. 2011 Apr 29;6(4):e18285. doi: 10.1371/journal.pone.0018285.

33.

Autoimmune sensitization to cardiac myosin leads to acute rejection of cardiac allografts in miniature swine.

Veillette GR, Sahara H, Meltzer AJ, Weiss MJ, Iwamoto Y, Kim KM, Rosengard BR, Allan JS, Houser SL, Sachs DH, Benichou G, Madsen JC.

Transplantation. 2011 Jun 15;91(11):1187-91. doi: 10.1097/TP.0b013e318218415d.

34.

Extracellular heat shock protein 90 plays a role in translocating chaperoned antigen from endosome to proteasome for generating antigenic peptide to be cross-presented by dendritic cells.

Oura J, Tamura Y, Kamiguchi K, Kutomi G, Sahara H, Torigoe T, Himi T, Sato N.

Int Immunol. 2011 Apr;23(4):223-37. doi: 10.1093/intimm/dxq475. Epub 2011 Mar 18.

PMID:
21421737
35.

Antibodies to parvovirus, distemper virus and adenovirus conferred to household dogs using commercial combination vaccines containing Leptospira bacterin.

Taguchi M, Namikawa K, Maruo T, Lynch J, Sahara H.

Vet Rec. 2010 Dec 11;167(24):931-4. doi: 10.1136/vr.c6225.

PMID:
21262693
36.

Identification of cancer stem cells derived from a canine lung adenocarcinoma cell line.

Nemoto Y, Maruo T, Sato T, Deguchi T, Ito T, Sugiyama H, Ishikawa T, Madarame H, Watanabe T, Shida T, Sahara H.

Vet Pathol. 2011 Sep;48(5):1029-34. doi: 10.1177/0300985810396106. Epub 2011 Jan 18.

PMID:
21245282
37.

Beneficial effects of perioperative low-dose inhaled carbon monoxide on pulmonary allograft survival in MHC-inbred CLAWN miniature swine.

Sahara H, Shimizu A, Setoyama K, Oku M, Okumi M, Nishimura H, Oriyanhan W, Tasaki M, Scalea J, Wada H, Bando T, Date H, Yamada K.

Transplantation. 2010 Dec 27;90(12):1336-43. doi: 10.1097/TP.0b013e3181ff8730.

PMID:
21076382
38.

The construction and application of diploid sake yeast with a homozygous mutation in the FAS2 gene.

Kotaka A, Sahara H, Hata Y.

J Biosci Bioeng. 2010 Dec;110(6):675-8. doi: 10.1016/j.jbiosc.2010.07.007. Epub 2010 Aug 12.

PMID:
20708434
39.

Enhancement of beta-glucosidase activity on the cell-surface of sake yeast by disruption of SED1.

Kotaka A, Sahara H, Kuroda K, Kondo A, Ueda M, Hata Y.

J Biosci Bioeng. 2010 May;109(5):442-6. doi: 10.1016/j.jbiosc.2009.11.003. Epub 2009 Dec 4.

PMID:
20347765
40.

Age-related changes in the trachea in healthy adults.

Sakai H, Nakano Y, Muro S, Hirai T, Takubo Y, Oku Y, Hamakawa H, Takahashi A, Sato T, Chen F, Sahara H, Fujinaga T, Sato K, Sonobe M, Shoji T, Miyahara R, Okubo K, Bando T, Hirata T, Date H, Mishima M.

Adv Exp Med Biol. 2010;662:115-20. doi: 10.1007/978-1-4419-1241-1_16.

41.

Carbon monoxide reduces pulmonary ischemia-reperfusion injury in miniature swine.

Sahara H, Shimizu A, Setoyama K, Okumi M, Oku M, Samelson-Jones E, Yamada K.

J Thorac Cardiovasc Surg. 2010 Jun;139(6):1594-601. doi: 10.1016/j.jtcvs.2009.09.016. Epub 2009 Nov 11.

42.

Using promoter replacement and selection for loss of heterozygosity to generate an industrially applicable sake yeast strain that homozygously overproduces isoamyl acetate.

Sahara H, Kotaka A, Kondo A, Ueda M, Hata Y.

J Biosci Bioeng. 2009 Nov;108(5):359-64. doi: 10.1016/j.jbiosc.2009.05.002.

PMID:
19804856
43.

Evaluation of cell surface-displayed protein stability against simulated gastric fluid.

Horii K, Adachi T, Tanino T, Tanaka T, Sahara H, Shibasaki S, Ogino C, Hata Y, Ueda M, Kondo A.

Biotechnol Lett. 2009 Aug;31(8):1259-64. doi: 10.1007/s10529-009-0006-5. Epub 2009 May 9.

PMID:
19430913
44.

Molecular pathological approaches to human tumor immunology.

Sato N, Hirohashi Y, Tsukahara T, Kikuchi T, Sahara H, Kamiguchi K, Ichimiya S, Tamura Y, Torigoe T.

Pathol Int. 2009 Apr;59(4):205-17. doi: 10.1111/j.1440-1827.2009.02353.x. Review. Erratum in: Pathol Int. 2009 Dec;59(12):900.

PMID:
19351363
45.

The indirect alloresponse impairs the induction but not maintenance of tolerance to MHC class I-disparate allografts.

Weiss MJ, Guenther DA, Mezrich JD, Sahara H, Ng CY, Meltzer AJ, Sayre JK, Cochrane ME, Pujara AC, Houser SL, Sachs DH, Rosengard BR, Allan JS, Benichou G, Madsen JC.

Am J Transplant. 2009 Jan;9(1):105-13.

46.

Efficient generation of recessive traits in diploid sake yeast by targeted gene disruption and loss of heterozygosity.

Kotaka A, Sahara H, Kondo A, Ueda M, Hata Y.

Appl Microbiol Biotechnol. 2009 Feb;82(2):387-95. doi: 10.1007/s00253-008-1833-3. Epub 2009 Jan 10.

PMID:
19137286
47.

Enhancement of display efficiency in yeast display system by vector engineering and gene disruption.

Kuroda K, Matsui K, Higuchi S, Kotaka A, Sahara H, Hata Y, Ueda M.

Appl Microbiol Biotechnol. 2009 Mar;82(4):713-9. doi: 10.1007/s00253-008-1808-4. Epub 2009 Jan 3.

PMID:
19123001
48.

Repetitive gastric aspiration leads to augmented indirect allorecognition after lung transplantation in miniature swine.

Meltzer AJ, Weiss MJ, Veillette GR, Sahara H, Ng CY, Cochrane ME, Houser SL, Sachs DH, Rosengard BR, Madsen JC, Wain JC, Allan JS.

Transplantation. 2008 Dec 27;86(12):1824-9. doi: 10.1097/TP.0b013e318190afe6.

49.

Immunosuppressive effect on T cell activation by interleukin-16- and interleukin-10-cDNA-double-transfected human squamous cell line.

Matsumoto Y, Fujita T, Hirai I, Sahara H, Torigoe T, Ezoe K, Saito T, Cruikshank WW, Yotsuyanagi T, Sato N.

Burns. 2009 May;35(3):383-9. doi: 10.1016/j.burns.2008.06.017. Epub 2008 Oct 23.

PMID:
18950955
50.

Construction of an Aspergillus oryzae cell-surface display system using a putative GPI-anchored protein.

Adachi T, Ito J, Kawata K, Kaya M, Ishida H, Sahara H, Hata Y, Ogino C, Fukuda H, Kondo A.

Appl Microbiol Biotechnol. 2008 Dec;81(4):711-9. doi: 10.1007/s00253-008-1687-8. Epub 2008 Sep 24.

PMID:
18813924

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