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Items: 1 to 50 of 74

1.

Editorial: Ethnopharmacological Studies for the Development of Drugs With Special Reference to Asteraceae.

Panda SK, da Silva LCN, Sahal D, Leonti M.

Front Pharmacol. 2019 Sep 3;10:955. doi: 10.3389/fphar.2019.00955. eCollection 2019. No abstract available.

2.

Antiplasmodial potential and GC-MS fingerprint of endophytic fungal extracts derived from Cameroonian Annona muricata.

Toghueo RMK, Kemgne EAM, Eke P, Kanko MIM, Dize D, Sahal D, Boyom FF.

J Ethnopharmacol. 2019 May 10;235:111-121. doi: 10.1016/j.jep.2019.02.010. Epub 2019 Feb 6.

PMID:
30738118
3.

Anti-proliferative and anti-malarial activities of spiroisoxazoline analogues of artemisinin.

Pratap S, Naaz F, Reddy S, Jha KK, Sharma K, Sahal D, Akhter M, Nayakanti D, Kumar HMS, Kumari V, Pandey K, Shafi S.

Arch Pharm (Weinheim). 2018 Dec 10:e1800192. doi: 10.1002/ardp.201800192. [Epub ahead of print]

PMID:
30537298
4.

Anti-Plasmodium falciparum Activity of Extracts from 10 Cameroonian Medicinal Plants.

Rufin Marie TK, Mbetyoumoun Mfouapon H, Madiesse Kemgne EA, Jiatsa Mbouna CD, Tsouh Fokou PV, Sahal D, Fekam Boyom F.

Medicines (Basel). 2018 Oct 29;5(4). pii: E115. doi: 10.3390/medicines5040115.

5.

Orally Effective Aminoalkyl 10H-Indolo[3,2-b]quinoline-11-carboxamide Kills the Malaria Parasite by Inhibiting Host Hemoglobin Uptake.

Mudududdla R, Mohanakrishnan D, Bharate SS, Vishwakarma RA, Sahal D, Bharate SB.

ChemMedChem. 2018 Dec 6;13(23):2581-2598. doi: 10.1002/cmdc.201800579. Epub 2018 Nov 13.

PMID:
30358112
6.

Evaluation of Antiplasmodial Potential of C2 and C8 Modified Quinolines: in vitro and in silico Study.

Kumar R, Sharma R, Kumar I, Upadhyay P, Dhiman AK, Kumar R, Kumar R, Purohit R, Sahal D, Sharma U.

Med Chem. 2019;15(7):790-800. doi: 10.2174/1573406414666181015144413.

PMID:
30324888
7.

Rh(III)-Catalyzed C(8)-H Functionalization of Quinolines via Simultaneous C-C and C-O Bond Formation: Direct Synthesis of Quinoline Derivatives with Antiplasmodial Potential.

Sharma R, Kumar R, Kumar R, Upadhyay P, Sahal D, Sharma U.

J Org Chem. 2018 Oct 19;83(20):12702-12710. doi: 10.1021/acs.joc.8b02042. Epub 2018 Oct 1.

PMID:
30211555
8.
9.

Strain-transcending neutralization of malaria parasite by antibodies against Plasmodium falciparum enolase.

Dutta S, Tewari A, Balaji C, Verma R, Moitra A, Yadav M, Agrawal P, Sahal D, Jarori GK.

Malar J. 2018 Aug 20;17(1):304. doi: 10.1186/s12936-018-2455-6.

10.

Facile synthesis of vanillin-based novel bischalcones identifies one that induces apoptosis and displays synergy with Artemisinin in killing chloroquine resistant Plasmodium falciparum.

Sharma UK, Mohanakrishnan D, Sharma N, Equbal D, Sahal D, Sinha AK.

Eur J Med Chem. 2018 Jul 15;155:623-638. doi: 10.1016/j.ejmech.2018.06.025. Epub 2018 Jun 15.

PMID:
29929118
11.

Antiplasmodial Properties and Cytotoxicity of Endophytic Fungi from Symphonia globulifera (Clusiaceae).

Ateba JET, Toghueo RMK, Awantu AF, Mba'ning BM, Gohlke S, Sahal D, Rodrigues-Filho E, Tsamo E, Boyom FF, Sewald N, Lenta BN.

J Fungi (Basel). 2018 Jun 12;4(2). pii: E70. doi: 10.3390/jof4020070.

12.

Conditioned media and organic elicitors underpin the production of potent antiplasmodial metabolites by endophytic fungi from Cameroonian medicinal plants.

Toghueo RMK, Sahal D, Zabalgogeazcoa Í, Baker B, Boyom FF.

Parasitol Res. 2018 Aug;117(8):2473-2485. doi: 10.1007/s00436-018-5936-1. Epub 2018 May 24.

PMID:
29797084
13.

Potent antiplasmodial extracts and fractions from Terminalia mantaly and Terminalia superba.

Mbouna CDJ, Kouipou RMT, Keumoe R, Tchokouaha LRY, Fokou PVT, Tali BMT, Sahal D, Boyom FF.

Malar J. 2018 Apr 3;17(1):142. doi: 10.1186/s12936-018-2298-1.

14.

Exploration of antiplasmodial activity in Acalypha wilkesiana Müller Argoviensis, 1866 (family: Euphorbiaceae) and its GC-MS fingerprint.

Amlabu WE, Nock IH, Kaushik NK, Mohanakrishnan D, Tiwary J, Audu PA, Abubakar MS, Sahal D.

Parasitol Res. 2018 May;117(5):1473-1484. doi: 10.1007/s00436-018-5802-1. Epub 2018 Mar 17.

PMID:
29550997
15.

Antimalarial and antiplasmodial activity of husk extract and fractions of Zea mays.

Okokon JE, Antia BS, Mohanakrishnan D, Sahal D.

Pharm Biol. 2017 Dec;55(1):1394-1400. doi: 10.1080/13880209.2017.1302966.

16.

Corrigendum: Leishmanicidal Activity of Piper nigrum Bioactive Fractions is Interceded via Apoptosis In Vitro and Substantiated by Th1 Immunostimulatory Potential In Vivo.

Chouhan G, Islamuddin M, Want MY, Ozbak HA, Hemeg HA, Sahal D, Afrin F.

Front Microbiol. 2016 Jun 20;7:944. doi: 10.3389/fmicb.2016.00944. eCollection 2016.

17.

Erratum to: Apoptosis mediated leishmanicidal activity of Azadirachta indica bioactive fractions is accompanied by Th1 immunostimulatory potential and therapeutic cure in vivo.

Chouhan G, Islamuddin M, Want MY, Abdin MZ, Ozbak HA, Hemeg HA, Sahal D, Afrin F.

Parasit Vectors. 2016 May 27;9(1):308. No abstract available.

18.

Leishmanicidal Activity of Piper nigrum Bioactive Fractions is Interceded via Apoptosis In Vitro and Substantiated by Th1 Immunostimulatory Potential In Vivo.

Chouhan G, Islamuddin M, Want MY, Ozbak HA, Hemeg HA, Sahal D, Afrin F.

Front Microbiol. 2015 Dec 8;6:1368. doi: 10.3389/fmicb.2015.01368. eCollection 2015. Erratum in: Front Microbiol. 2016;7:944.

19.

Corrigendum: Leishmanicidal activities of Artemisia annua leaf essential oil against Visceral Leishmaniasis.

Islamuddin M, Chouhan G, Want MY, Tyagi M, Abdin MZ, Sahal D, Afrin F.

Front Microbiol. 2015 Sep 24;6:1015. doi: 10.3389/fmicb.2015.01015. eCollection 2015.

20.

Apoptosis mediated leishmanicidal activity of Azadirachta indica bioactive fractions is accompanied by Th1 immunostimulatory potential and therapeutic cure in vivo.

Chouhan G, Islamuddin M, Want MY, Abdin MZ, Ozbak HA, Hemeg HA, Sahal D, Afrin F.

Parasit Vectors. 2015 Mar 26;8:183. doi: 10.1186/s13071-015-0788-3. Erratum in: Parasit Vectors. 2016;9(1):308.

21.

Evaluation of antiplasmodial activity of medicinal plants from North Indian Buchpora and South Indian Eastern Ghats.

Kaushik NK, Bagavan A, Rahuman AA, Zahir AA, Kamaraj C, Elango G, Jayaseelan C, Kirthi AV, Santhoshkumar T, Marimuthu S, Rajakumar G, Tiwari SK, Sahal D.

Malar J. 2015 Feb 7;14:65. doi: 10.1186/s12936-015-0564-z.

22.

Antiplasmodial activity of medicinal plants from Chhotanagpur plateau, Jharkhand, India.

Singh N, Kaushik NK, Mohanakrishnan D, Tiwari SK, Sahal D.

J Ethnopharmacol. 2015 May 13;165:152-62. doi: 10.1016/j.jep.2015.02.038. Epub 2015 Feb 24.

PMID:
25721804
23.

Th1-biased immunomodulation and therapeutic potential of Artemisia annua in murine visceral leishmaniasis.

Islamuddin M, Chouhan G, Farooque A, Dwarakanath BS, Sahal D, Afrin F.

PLoS Negl Trop Dis. 2015 Jan 8;9(1):e3321. doi: 10.1371/journal.pntd.0003321. eCollection 2015 Jan.

24.

Leishmanicidal activities of Artemisia annua leaf essential oil against Visceral Leishmaniasis.

Islamuddin M, Chouhan G, Tyagi M, Abdin MZ, Sahal D, Afrin F.

Front Microbiol. 2014 Nov 25;5:626. doi: 10.3389/fmicb.2014.00626. eCollection 2014. Erratum in: Front Microbiol. 2015;6:1015.

25.

Dendrimeric template of Plasmodium falciparum histidine rich protein II repeat motifs bearing Asp→Asn mutation exhibits heme binding and β-hematin formation.

Kumari P, Sahal D, Chauhan VS.

PLoS One. 2014 Nov 14;9(11):e112087. doi: 10.1371/journal.pone.0112087. eCollection 2014.

26.

A search for antiplasmodial metabolites among fungal endophytes of terrestrial and marine plants of southern India.

Kaushik NK, Murali TS, Sahal D, Suryanarayanan TS.

Acta Parasitol. 2014 Oct;59(4):745-57. doi: 10.2478/s11686-014-0307-2. Epub 2014 Sep 20.

PMID:
25236288
27.

Antiplasmodial activity of extracts of 25 cyanobacterial species from coastal regions of Tamil Nadu.

Veerabadhran M, Manivel N, Mohanakrishnan D, Sahal D, Muthuraman S.

Pharm Biol. 2014 Oct;52(10):1291-301. doi: 10.3109/13880209.2014.890231. Epub 2014 Jul 15.

PMID:
25026331
28.

Exploring the role of medicinal plant-based immunomodulators for effective therapy of leishmaniasis.

Chouhan G, Islamuddin M, Sahal D, Afrin F.

Front Immunol. 2014 May 5;5:193. doi: 10.3389/fimmu.2014.00193. eCollection 2014. Review.

29.

Synthesis and biological evaluation of some novel pyrido[1,2-a]pyrimidin-4-ones as antimalarial agents.

Mane UR, Mohanakrishnan D, Sahal D, Murumkar PR, Giridhar R, Yadav MR.

Eur J Med Chem. 2014 May 22;79:422-35. doi: 10.1016/j.ejmech.2014.04.031. Epub 2014 Apr 13.

PMID:
24763263
30.

Design, economical synthesis and antiplasmodial evaluation of vanillin derived allylated chalcones and their marked synergism with artemisinin against chloroquine resistant strains of Plasmodium falciparum.

Sharma N, Mohanakrishnan D, Sharma UK, Kumar R, Richa, Sinha AK, Sahal D.

Eur J Med Chem. 2014 May 22;79:350-68. doi: 10.1016/j.ejmech.2014.03.079. Epub 2014 Apr 1.

PMID:
24747290
31.

Apoptosis-like death in Leishmania donovani promastigotes induced by eugenol-rich oil of Syzygium aromaticum.

Islamuddin M, Sahal D, Afrin F.

J Med Microbiol. 2014 Jan;63(Pt 1):74-85. doi: 10.1099/jmm.0.064709-0. Epub 2013 Oct 25.

PMID:
24161990
32.

Evaluation of antiplasmodial activity of green synthesized silver nanoparticles.

Mishra A, Kaushik NK, Sardar M, Sahal D.

Colloids Surf B Biointerfaces. 2013 Nov 1;111:713-8. doi: 10.1016/j.colsurfb.2013.06.036. Epub 2013 Jul 9.

PMID:
23916962
33.

Antiplasmodial potential of selected medicinal plants from eastern Ghats of South India.

Kaushik NK, Bagavan A, Rahuman AA, Mohanakrishnan D, Kamaraj C, Elango G, Zahir AA, Sahal D.

Exp Parasitol. 2013 May;134(1):26-32. doi: 10.1016/j.exppara.2013.01.021. Epub 2013 Feb 9.

PMID:
23399920
34.

Bioactivity guided fractionation of leaves extract of Nyctanthes arbor tristis (Harshringar) against P falciparum.

Kumari P, Sahal D, Jain SK, Chauhan VS.

PLoS One. 2012;7(12):e51714. doi: 10.1371/journal.pone.0051714. Epub 2012 Dec 26.

35.

Extracts of Artemisia annua leaves and seeds mediate programmed cell death in Leishmania donovani.

Islamuddin M, Farooque A, Dwarakanath BS, Sahal D, Afrin F.

J Med Microbiol. 2012 Dec;61(Pt 12):1709-18. doi: 10.1099/jmm.0.049387-0. Epub 2012 Sep 6.

PMID:
22956747
36.

Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides.

Kaushik NK, Sharma J, Sahal D.

Malar J. 2012 Aug 1;11:256. doi: 10.1186/1475-2875-11-256.

37.

Antimalarial activities of medicinal plants traditionally used in the villages of Dharmapuri regions of South India.

Kamaraj C, Kaushik NK, Rahuman AA, Mohanakrishnan D, Bagavan A, Elango G, Zahir AA, Santhoshkumar T, Marimuthu S, Jayaseelan C, Kirthi AV, Rajakumar G, Velayutham K, Sahal D.

J Ethnopharmacol. 2012 Jun 14;141(3):796-802. doi: 10.1016/j.jep.2012.03.003. Epub 2012 Mar 13.

PMID:
22433533
38.

Stilbene-chalcone hybrids: design, synthesis, and evaluation as a new class of antimalarial scaffolds that trigger cell death through stage specific apoptosis.

Sharma N, Mohanakrishnan D, Shard A, Sharma A, Saima, Sinha AK, Sahal D.

J Med Chem. 2012 Jan 12;55(1):297-311. doi: 10.1021/jm201216y. Epub 2011 Dec 1.

PMID:
22098429
39.

Antiplasmodial potential of medicinal plant extracts from Malaiyur and Javadhu hills of South India.

Kamaraj C, Kaushik NK, Mohanakrishnan D, Elango G, Bagavan A, Zahir AA, Rahuman AA, Sahal D.

Parasitol Res. 2012 Aug;111(2):703-15. doi: 10.1007/s00436-011-2457-6. Epub 2011 Jun 4.

PMID:
21643655
40.

Tandem allylic oxidation-condensation/esterification catalyzed by silica gel: an expeditious approach towards antimalarial diaryldienones and enones from natural methoxylated phenylpropenes.

Sharma A, Sharma N, Shard A, Kumar R, Mohanakrishnan D, Saima, Sinha AK, Sahal D.

Org Biomol Chem. 2011 Jul 21;9(14):5211-9. doi: 10.1039/c1ob05293d. Epub 2011 May 31.

PMID:
21625717
41.

Isopeptide ligation catalyzed by quintessential sortase A: mechanistic cues from cyclic and branched oligomers of indolicidin.

Dasgupta S, Samantaray S, Sahal D, Roy RP.

J Biol Chem. 2011 Jul 8;286(27):23996-4006. doi: 10.1074/jbc.M111.247650. Epub 2011 May 12.

42.

Dibenzylideneacetone analogues as novel Plasmodium falciparum inhibitors.

Aher RB, Wanare G, Kawathekar N, Kumar RR, Kaushik NK, Sahal D, Chauhan VS.

Bioorg Med Chem Lett. 2011 May 15;21(10):3034-6. doi: 10.1016/j.bmcl.2011.03.037. Epub 2011 Apr 12.

PMID:
21493068
43.

Antiplasmodial activity of botanical extracts against Plasmodium falciparum.

Bagavan A, Rahuman AA, Kamaraj C, Kaushik NK, Mohanakrishnan D, Sahal D.

Parasitol Res. 2011 May;108(5):1099-109. doi: 10.1007/s00436-010-2151-0. Epub 2010 Nov 16.

PMID:
21079994
44.

Reinvestigation of structure-activity relationship of methoxylated chalcones as antimalarials: synthesis and evaluation of 2,4,5-trimethoxy substituted patterns as lead candidates derived from abundantly available natural β-asarone.

Kumar R, Mohanakrishnan D, Sharma A, Kaushik NK, Kalia K, Sinha AK, Sahal D.

Eur J Med Chem. 2010 Nov;45(11):5292-301. doi: 10.1016/j.ejmech.2010.08.049. Epub 2010 Sep 22.

PMID:
20863599
45.

In vitro antimalarial activity of medicinal plant extracts against Plasmodium falciparum.

Bagavan A, Rahuman AA, Kaushik NK, Sahal D.

Parasitol Res. 2011 Jan;108(1):15-22. doi: 10.1007/s00436-010-2034-4. Epub 2010 Sep 1.

PMID:
20809417
46.

Reverse engineering truncations of an antimicrobial peptide dimer to identify the origins of potency and broad spectrum of action.

Anantharaman A, Sahal D.

J Med Chem. 2010 Aug 26;53(16):6079-88. doi: 10.1021/jm100483y.

PMID:
20681539
47.

Synthesis of novel alpha-pyranochalcones and pyrazoline derivatives as Plasmodium falciparum growth inhibitors.

Wanare G, Aher R, Kawathekar N, Ranjan R, Kaushik NK, Sahal D.

Bioorg Med Chem Lett. 2010 Aug 1;20(15):4675-8. doi: 10.1016/j.bmcl.2010.05.069. Epub 2010 May 26.

PMID:
20576433
48.

Synergy with rifampin and kanamycin enhances potency, kill kinetics, and selectivity of de novo-designed antimicrobial peptides.

Anantharaman A, Rizvi MS, Sahal D.

Antimicrob Agents Chemother. 2010 May;54(5):1693-9. doi: 10.1128/AAC.01231-09. Epub 2010 Feb 22.

49.

Thermo and pH stable ATP-independent chaperone activity of heat-inducible Hsp70 from Pennisetum glaucum.

Rao JL, Reddy PS, Mishra RN, Gupta D, Sahal D, Tuteja N, Sopory SK, Reddy MK.

Plant Signal Behav. 2010 Feb;5(2):110-21. Epub 2010 Feb 9.

50.

Antimicrobial action of prototypic amphipathic cationic decapeptides and their branched dimers.

Dewan PC, Anantharaman A, Chauhan VS, Sahal D.

Biochemistry. 2009 Jun 23;48(24):5642-57. doi: 10.1021/bi900272r.

PMID:
19432402

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