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Items: 1 to 50 of 106

1.

Impact of dose and duration of therapy on dexamethasone pharmacokinetics in childhood acute lymphoblastic leukaemia-a report from the UKALL 2011 trial.

Jackson RK, Liebich M, Berry P, Errington J, Liu J, Parker C, Moppett J, Samarasinghe S, Hough R, Rowntree C, Goulden NJ, Vora A, Kearns PR, Saha V, Hempel G, Irving JAE, Veal GJ.

Eur J Cancer. 2019 Oct;120:75-85. doi: 10.1016/j.ejca.2019.07.026. Epub 2019 Sep 6.

PMID:
31499383
2.

Efficacy and safety of a bortezomib and reduced-intensity cytarabine-based protocol, TMC ALLR1, for relapsed childhood ALL in India.

Roy P, Islam R, Saha D, Gogoi M, Kumar Mishra D, Arora N, Parihar M, Krishnan S, Saha V.

Br J Haematol. 2019 Sep;186(6):861-865. doi: 10.1111/bjh.16005. Epub 2019 Jun 5.

PMID:
31168836
3.

Outcomes of patients with childhood B-cell precursor acute lymphoblastic leukaemia with late bone marrow relapses: long-term follow-up of the ALLR3 open-label randomised trial.

Parker C, Krishnan S, Hamadeh L, Irving JAE, Kuiper RP, Révész T, Hoogerbrugge P, Hancock J, Sutton R, Moorman AV, Saha V.

Lancet Haematol. 2019 Apr;6(4):e204-e216. doi: 10.1016/S2352-3026(19)30003-1. Epub 2019 Feb 27.

4.

Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial.

Biondi A, Gandemer V, De Lorenzo P, Cario G, Campbell M, Castor A, Pieters R, Baruchel A, Vora A, Leoni V, Stary J, Escherich G, Li CK, Cazzaniga G, Cavé H, Bradtke J, Conter V, Saha V, Schrappe M, Grazia Valsecchi M.

Lancet Haematol. 2018 Dec;5(12):e641-e652. doi: 10.1016/S2352-3026(18)30173-X.

PMID:
30501871
5.

Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor.

Biondi A, Cario G, De Lorenzo P, Castor A, Conter V, Leoni V, Gandemer V, Pieters R, Stary J, Escherich G, Campbell M, Attarbaschi A, Li CK, Vora A, Bradtke J, Saha V, Valsecchi MG, Schrappe M.

Haematologica. 2019 Jan;104(1):e13-e16. doi: 10.3324/haematol.2018.199422. Epub 2018 Sep 13. No abstract available.

6.

A triple-probe FISH screening strategy for risk-stratified therapy of acute lymphoblastic leukaemia in low-resource settings.

Parihar M, Singh MK, Islam R, Saha D, Mishra DK, Saha V, Krishnan S.

Pediatr Blood Cancer. 2018 Dec;65(12):e27366. doi: 10.1002/pbc.27366. Epub 2018 Aug 31.

7.

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies.

Cazzaniga G, De Lorenzo P, Alten J, Röttgers S, Hancock J, Saha V, Castor A, Madsen HO, Gandemer V, Cavé H, Leoni V, Köhler R, Ferrari GM, Bleckmann K, Pieters R, van der Velden V, Stary J, Zuna J, Escherich G, Stadt UZ, Aricò M, Conter V, Schrappe M, Valsecchi MG, Biondi A.

Haematologica. 2018 Jan;103(1):107-115. doi: 10.3324/haematol.2017.176917. Epub 2017 Oct 27.

8.

Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia.

Qattan MY, Bakker EY, Rajendran R, Chen DW, Saha V, Liu J, Zeef L, Schwartz JM, Mutti L, Demonacos C, Krstic-Demonacos M.

PLoS One. 2017 Jun 5;12(6):e0178606. doi: 10.1371/journal.pone.0178606. eCollection 2017.

9.

Acute lymphoblastic leukaemia cells produce large extracellular vesicles containing organelles and an active cytoskeleton.

Johnson SM, Dempsey C, Parker C, Mironov A, Bradley H, Saha V.

J Extracell Vesicles. 2017 Mar 10;6(1):1294339. doi: 10.1080/20013078.2017.1294339. eCollection 2017.

10.

Targeting the 5T4 oncofetal glycoprotein with an antibody drug conjugate (A1mcMMAF) improves survival in patient-derived xenograft models of acute lymphoblastic leukemia.

McGinn OJ, Krishnan S, Bourquin JP, Sapra P, Dempsey C, Saha V, Stern PL.

Haematologica. 2017 Jun;102(6):1075-1084. doi: 10.3324/haematol.2016.158485. Epub 2017 Mar 24.

11.

Mixed-phenotypic acute leukemia series from tertiary care center.

Pawar RN, Banerjee S, Bramha S, Krishnan S, Bhattacharya A, Saha V, Chakrapani A, Bhave S, Chandy M, Nair R, Parihar M, Arora N, Mishra DK.

Indian J Pathol Microbiol. 2017 Jan-Mar;60(1):43-49. doi: 10.4103/0377-4929.200057.

12.

Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia.

Frismantas V, Dobay MP, Rinaldi A, Tchinda J, Dunn SH, Kunz J, Richter-Pechanska P, Marovca B, Pail O, Jenni S, Diaz-Flores E, Chang BH, Brown TJ, Collins RH, Uhrig S, Balasubramanian GP, Bandapalli OR, Higi S, Eugster S, Voegeli P, Delorenzi M, Cario G, Loh ML, Schrappe M, Stanulla M, Kulozik AE, Muckenthaler MU, Saha V, Irving JA, Meisel R, Radimerski T, Von Stackelberg A, Eckert C, Tyner JW, Horvath P, Bornhauser BC, Bourquin JP.

Blood. 2017 Mar 16;129(11):e26-e37. doi: 10.1182/blood-2016-09-738070. Epub 2017 Jan 25.

13.

Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids.

Dutta A, Potier DN, Walker MJ, Gray OJ, Parker C, Holland M, Williamson AJ, Pierce A, Unwin RD, Krishnan S, Saha V, Whetton AD.

Oncotarget. 2016 Oct 25;7(43):70822-70831. doi: 10.18632/oncotarget.12224.

14.

SOX7 promotes the maintenance and proliferation of B cell precursor acute lymphoblastic cells.

Cuvertino S, Filiciotto G, Masurekar A, Saha V, Lacaud G, Kouskoff V.

Oncotarget. 2016 Jul 7;8(39):64974-64983. doi: 10.18632/oncotarget.10472. eCollection 2017 Sep 12.

15.

Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia.

Irving JA, Enshaei A, Parker CA, Sutton R, Kuiper RP, Erhorn A, Minto L, Venn NC, Law T, Yu J, Schwab C, Davies R, Matheson E, Davies A, Sonneveld E, den Boer ML, Love SB, Harrison CJ, Hoogerbrugge PM, Revesz T, Saha V, Moorman AV.

Blood. 2016 Aug 18;128(7):911-22. doi: 10.1182/blood-2016-03-704973. Epub 2016 May 26.

16.

Metabolic reprogramming of bone marrow stromal cells by leukemic extracellular vesicles in acute lymphoblastic leukemia.

Johnson SM, Dempsey C, Chadwick A, Harrison S, Liu J, Di Y, McGinn OJ, Fiorillo M, Sotgia F, Lisanti MP, Parihar M, Krishnan S, Saha V.

Blood. 2016 Jul 21;128(3):453-6. doi: 10.1182/blood-2015-12-688051. Epub 2016 Apr 20. No abstract available.

PMID:
27099150
17.

Myeloproliferative neoplasm with eosinophilia and T-lymphoblastic lymphoma with ETV6-LYN gene fusion.

Telford N, Alexander S, McGinn OJ, Williams M, Wood KM, Bloor A, Saha V.

Blood Cancer J. 2016 Apr 8;6:e412. doi: 10.1038/bcj.2016.11. No abstract available.

18.

EBF1-PDGFRB fusion in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL): genetic profile and clinical implications.

Schwab C, Ryan SL, Chilton L, Elliott A, Murray J, Richardson S, Wragg C, Moppett J, Cummins M, Tunstall O, Parker CA, Saha V, Goulden N, Vora A, Moorman AV, Harrison CJ.

Blood. 2016 May 5;127(18):2214-8. doi: 10.1182/blood-2015-09-670166. Epub 2016 Feb 12.

PMID:
26872634
19.

Earlier Goals of Care Discussions in Hospitalized Terminally Ill Patients and the Quality of End-of-Life Care: A Retrospective Study.

Gieniusz M, Nunes R, Saha V, Renson A, Schubert FD, Carey J.

Am J Hosp Palliat Care. 2018 Jan;35(1):21-27. doi: 10.1177/1049909116682470. Epub 2016 Dec 13.

PMID:
28273751
20.

Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia.

Liu J, Masurekar A, Johnson S, Chakraborty S, Griffiths J, Smith D, Alexander S, Dempsey C, Parker C, Harrison S, Li Y, Miller C, Di Y, Ghosh Z, Krishnan S, Saha V.

Oncotarget. 2015 Dec 15;6(40):43048-64. doi: 10.18632/oncotarget.5528.

21.

Creating a unique, multi-stakeholder Paediatric Oncology Platform to improve drug development for children and adolescents with cancer.

Vassal G, Rousseau R, Blanc P, Moreno L, Bode G, Schwoch S, Schrappe M, Skolnik J, Bergman L, Bradley-Garelik MB, Saha V, Pearson A, Zwierzina H.

Eur J Cancer. 2015 Jan;51(2):218-24. doi: 10.1016/j.ejca.2014.10.029. Epub 2014 Nov 27.

22.

Outcome of central nervous system relapses in childhood acute lymphoblastic leukaemia--prospective open cohort analyses of the ALLR3 trial.

Masurekar AN, Parker CA, Shanyinde M, Moorman AV, Hancock JP, Sutton R, Ancliff PJ, Morgan M, Goulden NJ, Fraser C, Hoogerbrugge PM, Revesz T, Darbyshire PJ, Krishnan S, Love SB, Saha V.

PLoS One. 2014 Oct 3;9(10):e108107. doi: 10.1371/journal.pone.0108107. eCollection 2014.

23.

Microbiology, infection control and infection related outcome in pediatric patients in an oncology center in Eastern India: Experience from Tata Medical Center, Kolkata.

Bhattacharyya A, Krishnan S, Saha V, Goel G, Bhattacharya S, Hmar L.

Indian J Cancer. 2014 Oct-Dec;51(4):415-7. doi: 10.4103/0019-509X.175365.

24.

The optimal use of PEG-asparaginase in relapsed ALL--lessons from the ALLR3 Clinical Trial.

Masurekar A, Fong C, Hussein A, Revesz T, Hoogerbrugge PM, Love S, Ciria C, Parker C, Krishnan S, Saha V.

Blood Cancer J. 2014 Apr 25;4:e203. doi: 10.1038/bcj.2014.26. No abstract available.

25.

Identification of facial nerve during parotidectomy: a combined anatomical & surgical study.

Saha S, Pal S, Sengupta M, Chowdhury K, Saha VP, Mondal L.

Indian J Otolaryngol Head Neck Surg. 2014 Jan;66(1):63-8. doi: 10.1007/s12070-013-0669-z. Epub 2013 Jul 24.

26.

EVI1 expression in childhood acute lymphoblastic leukaemia is not restricted to MLL and BCR/ABL rearrangements and is influenced by age.

Stevens A, Hanson D, de Leonibus C, Whatmore A, Donn R, White DJ, Liu J, van den Heuvel-Eibrink MM, Saha V, Clayton PE, Meyer S.

Blood Cancer J. 2014 Jan 24;4:e179. doi: 10.1038/bcj.2013.76. No abstract available.

27.

Study on developmental-behavioural pediatrics training experiences of pediatricians and pediatric trainees working in Nepal.

Rimal HS, Pokharel A, Saha V.

Kathmandu Univ Med J (KUMJ). 2013 Jul-Sep;11(43):191-5.

PMID:
24442163
28.

Congenital midline cervical cleft: a 7 year prospective study.

Saha VP, Pal S, Saha S, Misra S.

Indian J Otolaryngol Head Neck Surg. 2013 Dec;65(4):367-70. doi: 10.1007/s12070-013-0670-6. Epub 2013 Jul 14.

29.

Pre and post operative voice analysis after medialization thyroplasty in cases of unilateral vocal fold paralysis.

Chowdhury K, Saha S, Saha VP, Pal S, Chatterjee I.

Indian J Otolaryngol Head Neck Surg. 2013 Dec;65(4):354-7. doi: 10.1007/s12070-013-0649-3. Epub 2013 Mar 23.

30.

IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

van der Veer A, Zaliova M, Mottadelli F, De Lorenzo P, Te Kronnie G, Harrison CJ, Cavé H, Trka J, Saha V, Schrappe M, Pieters R, Biondi A, Valsecchi MG, Stanulla M, den Boer ML, Cazzaniga G.

Blood. 2014 Mar 13;123(11):1691-8. doi: 10.1182/blood-2013-06-509794. Epub 2013 Dec 23.

PMID:
24366361
31.

Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study.

Biondi A, Schrappe M, De Lorenzo P, Castor A, Lucchini G, Gandemer V, Pieters R, Stary J, Escherich G, Campbell M, Li CK, Vora A, Aricò M, Röttgers S, Saha V, Valsecchi MG.

Lancet Oncol. 2012 Sep;13(9):936-45. doi: 10.1016/S1470-2045(12)70377-7. Epub 2012 Aug 14.

32.

Erg and AP-1 as determinants of glucocorticoid response in acute lymphoblastic leukemia.

Chen DW, Saha V, Liu JZ, Schwartz JM, Krstic-Demonacos M.

Oncogene. 2013 Jun 20;32(25):3039-48. doi: 10.1038/onc.2012.321. Epub 2012 Aug 6.

PMID:
22869147
33.

Outcomes after induction failure in childhood acute lymphoblastic leukemia.

Schrappe M, Hunger SP, Pui CH, Saha V, Gaynon PS, Baruchel A, Conter V, Otten J, Ohara A, Versluys AB, Escherich G, Heyman M, Silverman LB, Horibe K, Mann G, Camitta BM, Harbott J, Riehm H, Richards S, Devidas M, Zimmermann M.

N Engl J Med. 2012 Apr 12;366(15):1371-81. doi: 10.1056/NEJMoa1110169.

34.

5T4 oncofetal antigen is expressed in high risk of relapse childhood pre-B acute lymphoblastic leukemia and is associated with a more invasive and chemotactic phenotype.

Castro FV, McGinn OJ, Krishnan S, Marinov G, Li J, Rutkowski AJ, Elkord E, Burt DJ, Holland M, Vaghjiani R, Gallego A, Saha V, Stern PL.

Leukemia. 2012 Jul;26(7):1487-98. doi: 10.1038/leu.2012.18. Epub 2012 Jan 23.

35.

RAC2, AEP, and ICAM1 expression are associated with CNS disease in a mouse model of pre-B childhood acute lymphoblastic leukemia.

Holland M, Castro FV, Alexander S, Smith D, Liu J, Walker M, Bitton D, Mulryan K, Ashton G, Blaylock M, Bagley S, Connolly Y, Bridgeman J, Miller C, Krishnan S, Dempsey C, Masurekar A, Stern P, Whetton A, Saha V.

Blood. 2011 Jul 21;118(3):638-49. doi: 10.1182/blood-2010-09-307330. Epub 2011 May 23.

PMID:
21606482
36.

Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.

van Delft FW, Horsley S, Colman S, Anderson K, Bateman C, Kempski H, Zuna J, Eckert C, Saha V, Kearney L, Ford A, Greaves M.

Blood. 2011 Jun 9;117(23):6247-54. doi: 10.1182/blood-2010-10-314674. Epub 2011 Apr 11.

PMID:
21482711
37.

Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial.

Parker C, Waters R, Leighton C, Hancock J, Sutton R, Moorman AV, Ancliff P, Morgan M, Masurekar A, Goulden N, Green N, Révész T, Darbyshire P, Love S, Saha V.

Lancet. 2010 Dec 11;376(9757):2009-17. doi: 10.1016/S0140-6736(10)62002-8. Epub 2010 Dec 3.

38.

Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity.

Offman MN, Krol M, Patel N, Krishnan S, Liu J, Saha V, Bates PA.

Blood. 2011 Feb 3;117(5):1614-21. doi: 10.1182/blood-2010-07-298422. Epub 2010 Nov 24.

PMID:
21106986
39.

Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.

Aricò M, Schrappe M, Hunger SP, Carroll WL, Conter V, Galimberti S, Manabe A, Saha V, Baruchel A, Vettenranta K, Horibe K, Benoit Y, Pieters R, Escherich G, Silverman LB, Pui CH, Valsecchi MG.

J Clin Oncol. 2010 Nov 1;28(31):4755-61. doi: 10.1200/JCO.2010.30.1325. Epub 2010 Sep 27.

40.

Hospital ventilation, heat and humidity: risk of fungal and other infections.

Saha V, Shanson E, Shankar A, Samuel D, Millar M.

J Hosp Infect. 2010 May;75(1):74-5. doi: 10.1016/j.jhin.2009.11.009. Epub 2010 Mar 15. No abstract available.

PMID:
20227142
41.

Temporal changes in the incidence and pattern of central nervous system relapses in children with acute lymphoblastic leukaemia treated on four consecutive Medical Research Council trials, 1985-2001.

Krishnan S, Wade R, Moorman AV, Mitchell C, Kinsey SE, Eden TO, Parker C, Vora A, Richards S, Saha V.

Leukemia. 2010 Feb;24(2):450-9. doi: 10.1038/leu.2009.264. Epub 2009 Dec 17.

42.

A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug L-asparaginase.

Patel N, Krishnan S, Offman MN, Krol M, Moss CX, Leighton C, van Delft FW, Holland M, Liu J, Alexander S, Dempsey C, Ariffin H, Essink M, Eden TO, Watts C, Bates PA, Saha V.

J Clin Invest. 2009 Jul;119(7):1964-73. doi: 10.1172/JCI37977. Epub 2009 Jun 8.

43.

Infratemporal fossa myoepithelial carcinoma--a rare case report.

Ghosh A, Saha S, Saha VP, Sadhu A, Chattopadhyay S.

Oral Maxillofac Surg. 2009 Mar;13(1):59-62. doi: 10.1007/s10006-009-0149-5.

PMID:
19184133
44.

Cutaneous matastasis from sino-nasal malignant melanoma - a rare case report.

Saha VP, Srivastava A, Saha S, Ghosh A, Chakraborty D.

Indian J Otolaryngol Head Neck Surg. 2008 Dec;60(4):369-72. doi: 10.1007/s12070-008-0118-6. Epub 2009 Jan 28.

45.

Orbital and para-orbital tumours--a 10 years retrospective study.

Saha S, Ghosh A, Jha A, Saha VP, Chatterjee SS, Dutra A, Bhaduri G.

J Indian Med Assoc. 2007 Aug;105(8):443-4, 446-8.

PMID:
18236907
46.

Sarcomas of head and neck - A 10 yrs experience.

Srivastava A, Ghosh A, Saha S, Saha VP, Chakraborty D.

Indian J Otolaryngol Head Neck Surg. 2007 Dec;59(4):322-6. doi: 10.1007/s12070-007-0093-3. Epub 2007 Dec 11.

47.

Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization.

Strefford JC, Worley H, Barber K, Wright S, Stewart AR, Robinson HM, Bettney G, van Delft FW, Atherton MG, Davies T, Griffiths M, Hing S, Ross FM, Talley P, Saha V, Moorman AV, Harrison CJ.

Oncogene. 2007 Jun 21;26(29):4306-18. Epub 2007 Jan 22.

PMID:
17237825
48.

Simplifying treatment for children with ALL.

Saha V.

Lancet. 2007 Jan 13;369(9556):82-3. No abstract available.

PMID:
17223452
49.

Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.

Strefford JC, van Delft FW, Robinson HM, Worley H, Yiannikouris O, Selzer R, Richmond T, Hann I, Bellotti T, Raghavan M, Young BD, Saha V, Harrison CJ.

Proc Natl Acad Sci U S A. 2006 May 23;103(21):8167-72. Epub 2006 May 15.

50.

Qualified predictions for microarray and proteomics pattern diagnostics with confidence machines.

Bellotti T, Luo Z, Gammerman A, Van Delft FW, Saha V.

Int J Neural Syst. 2005 Aug;15(4):247-58.

PMID:
16187401

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