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Items: 16

1.

Phosphorylation of the phosphatase PTPROt at Tyr399 is a molecular switch that controls osteoclast activity and bone mass in vivo.

Roth L, Wakim J, Wasserman E, Shalev M, Arman E, Stein M, Brumfeld V, Sagum CA, Bedford MT, Tuckermann J, Elson A.

Sci Signal. 2019 Jan 8;12(563). pii: eaau0240. doi: 10.1126/scisignal.aau0240.

PMID:
30622194
2.

Correction to "Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID subunit 1".

Suh JL, Watts B, Stuckey JI, Norris-Drouin JL, Cholensky SH, Dickson BM, An Y, Mathea S, Salah E, Knapp S, Khan A, Adams AT, Strahl BD, Sagum CA, Bedford MT, James LI, Kireev DB, Frye SV.

Biochemistry. 2018 Nov 28. doi: 10.1021/acs.biochem.8b01187. [Epub ahead of print] No abstract available.

PMID:
30485080
3.

Host Protein BAG3 is a Negative Regulator of Lassa VLP Egress.

Han Z, Schwoerer MP, Hicks P, Liang J, Ruthel G, Berry CT, Freedman BD, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Harty RN.

Diseases. 2018 Jul 13;6(3). pii: E64. doi: 10.3390/diseases6030064.

4.

Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1.

Suh JL, Watts B, Stuckey JI, Norris-Drouin JL, Cholensky SH, Dickson BM, An Y, Mathea S, Salah E, Knapp S, Khan A, Adams AT, Strahl BD, Sagum CA, Bedford MT, James LI, Kireev DB, Frye SV.

Biochemistry. 2018 Apr 10;57(14):2140-2149. doi: 10.1021/acs.biochem.8b00150. Epub 2018 Mar 28.

5.

Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein.

Carr SM, Munro S, Sagum CA, Fedorov O, Bedford MT, La Thangue NB.

Cell Death Differ. 2017 Dec;24(12):2139-2149. doi: 10.1038/cdd.2017.135. Epub 2017 Aug 25.

6.

Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress.

Han Z, Sagum CA, Takizawa F, Ruthel G, Berry CT, Kong J, Sunyer JO, Freedman BD, Bedford MT, Sidhu SS, Sudol M, Harty RN.

J Virol. 2017 Sep 27;91(20). pii: e00812-17. doi: 10.1128/JVI.00812-17. Print 2017 Oct 15.

7.

Correction: Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.

Liang J, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Han Z, Harty RN.

PLoS Pathog. 2017 Jul 19;13(7):e1006519. doi: 10.1371/journal.ppat.1006519. eCollection 2017 Jul.

8.

Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation.

Gates LA, Shi J, Rohira AD, Feng Q, Zhu B, Bedford MT, Sagum CA, Jung SY, Qin J, Tsai MJ, Tsai SY, Li W, Foulds CE, O'Malley BW.

J Biol Chem. 2017 Sep 1;292(35):14456-14472. doi: 10.1074/jbc.M117.802074. Epub 2017 Jul 17.

9.

Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.

Liang J, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Han Z, Harty RN.

PLoS Pathog. 2017 Jan 11;13(1):e1006132. doi: 10.1371/journal.ppat.1006132. eCollection 2017 Jan. Erratum in: PLoS Pathog. 2017 Jul 19;13(7):e1006519.

10.

ITCH E3 Ubiquitin Ligase Interacts with Ebola Virus VP40 To Regulate Budding.

Han Z, Sagum CA, Bedford MT, Sidhu SS, Sudol M, Harty RN.

J Virol. 2016 Sep 29;90(20):9163-71. doi: 10.1128/JVI.01078-16. Print 2016 Oct 15.

11.

G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression.

Zhang X, Peng D, Xi Y, Yuan C, Sagum CA, Klein BJ, Tanaka K, Wen H, Kutateladze TG, Li W, Bedford MT, Shi X.

Nat Commun. 2016 Mar 10;7:10810. doi: 10.1038/ncomms10810.

12.

Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus.

Hu SB, Xiang JF, Li X, Xu Y, Xue W, Huang M, Wong CC, Sagum CA, Bedford MT, Yang L, Cheng D, Chen LL.

Genes Dev. 2015 Mar 15;29(6):630-45. doi: 10.1101/gad.257048.114.

13.

Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor.

Carr SM, Munro S, Zalmas LP, Fedorov O, Johansson C, Krojer T, Sagum CA, Bedford MT, Oppermann U, La Thangue NB.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11341-6. doi: 10.1073/pnas.1403737111. Epub 2014 Jul 21.

14.

The tumour suppressor gene WWOX is mutated in autosomal recessive cerebellar ataxia with epilepsy and mental retardation.

Mallaret M, Synofzik M, Lee J, Sagum CA, Mahajnah M, Sharkia R, Drouot N, Renaud M, Klein FA, Anheim M, Tranchant C, Mignot C, Mandel JL, Bedford M, Bauer P, Salih MA, Schüle R, Schöls L, Aldaz CM, Koenig M.

Brain. 2014 Feb;137(Pt 2):411-9. doi: 10.1093/brain/awt338. Epub 2013 Dec 24.

15.

Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1.

Zheng S, Moehlenbrink J, Lu YC, Zalmas LP, Sagum CA, Carr S, McGouran JF, Alexander L, Fedorov O, Munro S, Kessler B, Bedford MT, Yu Q, La Thangue NB.

Mol Cell. 2013 Oct 10;52(1):37-51. doi: 10.1016/j.molcel.2013.08.039. Epub 2013 Sep 26.

16.

Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.

James LI, Barsyte-Lovejoy D, Zhong N, Krichevsky L, Korboukh VK, Herold JM, MacNevin CJ, Norris JL, Sagum CA, Tempel W, Marcon E, Guo H, Gao C, Huang XP, Duan S, Emili A, Greenblatt JF, Kireev DB, Jin J, Janzen WP, Brown PJ, Bedford MT, Arrowsmith CH, Frye SV.

Nat Chem Biol. 2013 Mar;9(3):184-91. doi: 10.1038/nchembio.1157. Epub 2013 Jan 6.

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