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Items: 25


Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord.

Delile J, Rayon T, Melchionda M, Edwards A, Briscoe J, Sagner A.

Development. 2019 Mar 27;146(12). pii: dev173807. doi: 10.1242/dev.173807.


G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.

Pusapati GV, Kong JH, Patel BB, Gouti M, Sagner A, Sircar R, Luchetti G, Ingham PW, Briscoe J, Rohatgi R.

Sci Signal. 2018 Feb 6;11(516). pii: eaao5749. doi: 10.1126/scisignal.aao5749.


CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.

Pusapati GV, Kong JH, Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R.

Dev Cell. 2018 Jan 22;44(2):271. doi: 10.1016/j.devcel.2018.01.002. No abstract available.


Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics.

Sagner A, Gaber ZB, Delile J, Kong JH, Rousso DL, Pearson CA, Weicksel SE, Melchionda M, Mousavy Gharavy SN, Briscoe J, Novitch BG.

PLoS Biol. 2018 Feb 1;16(2):e2003127. doi: 10.1371/journal.pbio.2003127. eCollection 2018 Feb.


CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.

Pusapati GV, Kong JH, Patel BB, Krishnan A, Sagner A, Kinnebrew M, Briscoe J, Aravind L, Rohatgi R.

Dev Cell. 2018 Jan 8;44(1):113-129.e8. doi: 10.1016/j.devcel.2017.12.003. Epub 2017 Dec 28. Erratum in: Dev Cell. 2018 Jan 22;44(2):271.


PreMosa: extracting 2D surfaces from 3D microscopy mosaics.

Blasse C, Saalfeld S, Etournay R, Sagner A, Eaton S, Myers EW.

Bioinformatics. 2017 Aug 15;33(16):2563-2569. doi: 10.1093/bioinformatics/btx195.


Morphogen interpretation: concentration, time, competence, and signaling dynamics.

Sagner A, Briscoe J.

Wiley Interdiscip Rev Dev Biol. 2017 Jul;6(4). doi: 10.1002/wdev.271. Epub 2017 Mar 20. Review.


Quantitative methods to study epithelial morphogenesis and polarity.

Aigouy B, Collinet C, Merkel M, Sagner A.

Methods Cell Biol. 2017;139:121-152. doi: 10.1016/bs.mcb.2016.12.004. Epub 2017 Jan 17. Review.


Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling.

Luchetti G, Sircar R, Kong JH, Nachtergaele S, Sagner A, Byrne EF, Covey DF, Siebold C, Rohatgi R.

Elife. 2016 Oct 5;5. pii: e20304. doi: 10.7554/eLife.20304.


Clustering and negative feedback by endocytosis in planar cell polarity signaling is modulated by ubiquitinylation of prickle.

Cho B, Pierre-Louis G, Sagner A, Eaton S, Axelrod JD.

PLoS Genet. 2015 May 21;11(5):e1005259. doi: 10.1371/journal.pgen.1005259. eCollection 2015 May.


Endogenously tagged rab proteins: a resource to study membrane trafficking in Drosophila.

Dunst S, Kazimiers T, von Zadow F, Jambor H, Sagner A, Brankatschk B, Mahmoud A, Spannl S, Tomancak P, Eaton S, Brankatschk M.

Dev Cell. 2015 May 4;33(3):351-65. doi: 10.1016/j.devcel.2015.03.022.


The balance of prickle/spiny-legs isoforms controls the amount of coupling between core and fat PCP systems.

Merkel M, Sagner A, Gruber FS, Etournay R, Blasse C, Myers E, Eaton S, Jülicher F.

Curr Biol. 2014 Sep 22;24(18):2111-2123. doi: 10.1016/j.cub.2014.08.005. Epub 2014 Sep 4.


Establishment of global patterns of planar polarity during growth of the Drosophila wing epithelium.

Sagner A, Merkel M, Aigouy B, Gaebel J, Brankatschk M, Jülicher F, Eaton S.

Curr Biol. 2012 Jul 24;22(14):1296-301. doi: 10.1016/j.cub.2012.04.066. Epub 2012 Jun 21.


Quantitative assessment of the embryotoxic potential of NSO-heterocyclic compounds using zebrafish (Danio rerio).

Peddinghaus S, Brinkmann M, Bluhm K, Sagner A, Hinger G, Braunbeck T, Eisenträger A, Tiehm A, Hollert H, Keiter SH.

Reprod Toxicol. 2012 Apr;33(2):224-32. doi: 10.1016/j.reprotox.2011.12.005. Epub 2012 Jan 5.


Importance of heterocylic aromatic compounds in monitored natural attenuation for coal tar contaminated aquifers: A review.

Blum P, Sagner A, Tiehm A, Martus P, Wendel T, Grathwohl P.

J Contam Hydrol. 2011 Nov 1;126(3-4):181-94. doi: 10.1016/j.jconhyd.2011.08.004. Epub 2011 Aug 22. Review.


Some heterocyclic aromatic compounds are Ah receptor agonists in the DR-CALUX assay and the EROD assay with RTL-W1 cells.

Hinger G, Brinkmann M, Bluhm K, Sagner A, Takner H, Eisenträger A, Braunbeck T, Engwall M, Tiehm A, Hollert H.

Environ Sci Pollut Res Int. 2011 Sep;18(8):1297-304. doi: 10.1007/s11356-011-0483-7. Epub 2011 Mar 23.


[Cell flow reorients planar polarity in the wing of Drosophila].

Aigouy B, Etournay R, Sagner A, Staple DB, Farhadifar R, Röper JC, Eaton S, Jülicher F.

Med Sci (Paris). 2011 Feb;27(2):117-9. doi: 10.1051/medsci/2011272117. Epub 2011 Mar 8. French. No abstract available.


Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila.

Aigouy B, Farhadifar R, Staple DB, Sagner A, Röper JC, Jülicher F, Eaton S.

Cell. 2010 Sep 3;142(5):773-86. doi: 10.1016/j.cell.2010.07.042.


Heterocyclic compounds: toxic effects using algae, daphnids, and the Salmonella/microsome test taking methodical quantitative aspects into account.

Eisentraeger A, Brinkmann C, Hollert H, Sagner A, Tiehm A, Neuwoehner J.

Environ Toxicol Chem. 2008 Jul;27(7):1590-6. doi: 10.1897/07-201.


The influence of immunosuppressive drugs on T- and B-cell apoptosis via p53-mediated pathway in vitro and in vivo.

Boldt A, Barten MJ, Sagner A, Mohr FW, Adams V, Dhein S, Gummert JF.

Transplantation. 2006 Aug 15;82(3):422-7.


Novel apoptosis assay to analyze immunosuppression.

Boldt A, Barten MJ, Weiss C, Sagner A, Mohr FW, Gummert JF.

Cytometry A. 2006 Mar;69(3):158-60.


[Gerontologic studies in South Africa--a report].

Sagner A.

Z Gerontol Geriatr. 1998 Feb;31(1):22-6. Review. German.


Services to pensioners and how they might be improved. A report from Malmö.

Bolin A, Lindstrom B, Sagner A, Svanström L.

Scand J Soc Med. 1976;4(3):151-7.


On pensioners' circumstances in a large Swedish city. A report from Malmö.

Bolin A, Lindström B, Sagnér A, Svanström L.

Scand J Soc Med. 1976;4(2):75-83.


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