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Items: 1 to 50 of 72

1.

Protocol for a systematic scoping review of reasons given to justify the performance of randomised controlled trials.

Dewar B, Fedyk M, Jurkovic L, Chevrier S, Rodriguez R, Kitto SC, Saginur R, Shamy M.

BMJ Open. 2019 Jul 26;9(7):e027575. doi: 10.1136/bmjopen-2018-027575.

2.

FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial.

McIntyre L, Taljaard M, McArdle T, Fox-Robichaud A, English SW, Martin C, Marshall J, Menon K, Muscedere J, Cook DJ, Weijer C, Saginur R, Maybee A, Iyengar A, Forster A, Graham ID, Hawken S, McCartney C, Seely AJ, Stiell IG, Thavorn K, Fergusson DA.

BMJ Open. 2018 Aug 23;8(8):e022780. doi: 10.1136/bmjopen-2018-022780.

3.

Acute rheumatic fever in First Nations communities in northwestern Ontario: Social determinants of health "bite the heart".

Gordon J, Kirlew M, Schreiber Y, Saginur R, Bocking N, Blakelock B, Haavaldsrud M, Kennedy C, Farrell T, Douglas L, Kelly L.

Can Fam Physician. 2015 Oct;61(10):881-6.

4.

Management of infectious diseases in remote northwestern Ontario with telemedicine videoconference consultations.

Mashru J, Kirlew M, Saginur R, Schreiber YS.

J Telemed Telecare. 2017 Jan;23(1):83-87. doi: 10.1177/1357633X15625136. Epub 2016 Jul 9.

PMID:
26748393
5.

Fever in our First Nations.

Gordon J, Kirlew M, Saginur R, Bocking N, Kelly L, Kennedy C, Farrell T, Schreiber Y.

CMAJ. 2015 Sep 22;187(13):996. doi: 10.1503/cmaj.1150058. No abstract available.

6.

A Scoping Review of Empirical Research Relating to Quality and Effectiveness of Research Ethics Review.

Nicholls SG, Hayes TP, Brehaut JC, McDonald M, Weijer C, Saginur R, Fergusson D.

PLoS One. 2015 Jul 30;10(7):e0133639. doi: 10.1371/journal.pone.0133639. eCollection 2015.

7.

Elements of informed consent and decision quality were poorly correlated in informed consent documents.

Brehaut JC, Carroll K, Elwyn G, Saginur R, Kimmelman J, Shojania K, Syrowatka A, Nguyen T, Fergusson D.

J Clin Epidemiol. 2015 Dec;68(12):1472-80. doi: 10.1016/j.jclinepi.2015.03.002. Epub 2015 Mar 7. Review.

PMID:
25857675
8.

Vancomycin use in a rural hospital: a 3-year retrospective study.

Bollinger M, Hamilton M, Schroeder K, Link S, Nguyen J, Chu D, Hopman W, Saginur R, Kelly L.

Can J Rural Med. 2015 Spring;20(2):56-62.

PMID:
25849753
9.

Epidemiology and outcomes of bloodstream infections in patients discharged from the emergency department.

Chan J, Wong J, Saginur R, Forster AJ, van Walraven C.

CJEM. 2015 Jan;17(1):27-37. doi: 10.2310/8000.2013.131349.

PMID:
25781381
10.

What makes public health studies ethical? Dissolving the boundary between research and practice.

Willison DJ, Ondrusek N, Dawson A, Emerson C, Ferris LE, Saginur R, Sampson H, Upshur R.

BMC Med Ethics. 2014 Aug 8;15:61. doi: 10.1186/1472-6939-15-61.

11.

Invasive CA-MRSA in northwestern Ontario: a 2-year prospective study.

Kirlew M, Rea S, Schroeter A, Makahnouk D, Hamilton M, Brunton N, Muileboom J, Schreiber Y, Saginur R, Kelly L.

Can J Rural Med. 2014 Summer;19(3):99-102.

PMID:
24991860
12.

Variability in research ethics review of cluster randomized trials: a scenario-based survey in three countries.

Taljaard M, Brehaut JC, Weijer C, Boruch R, Donner A, Eccles MP, McRae AD, Saginur R, Zwarenstein M, Grimshaw JM.

Trials. 2014 Feb 5;15:48. doi: 10.1186/1745-6215-15-48.

13.

Community-associated methicillin-resistant Staphylococcus aureus in northwest Ontario: A five-year report of incidence and antibiotic resistance.

Muileboom J, Hamilton M, Parent K, Makahnouk D, Kirlew M, Saginur R, Lam F, Kelly L.

Can J Infect Dis Med Microbiol. 2013 Summer;24(2):e42-4.

14.

Survey of consent practices in cluster randomized trials: improvements are needed in ethical conduct and reporting.

Taljaard M, Chaudhry SH, Brehaut JC, Weijer C, Boruch R, Donner A, Eccles MP, McRae AD, Saginur R, Zwarenstein M, Grimshaw JM.

Clin Trials. 2014 Feb;11(1):60-9. doi: 10.1177/1740774513513658. Epub 2013 Dec 17.

PMID:
24346609
15.

Protecting human research participants: reading vs understanding the consent form.

Holland J, Browman G, McDonald M, Saginur R.

J Natl Cancer Inst. 2013 Jul 3;105(13):927-8. doi: 10.1093/jnci/djt152. No abstract available.

PMID:
23821756
16.

Detection, treatment, and prevention of carbapenemase-producing Enterobacteriaceae: recommendations from an International Working Group.

Levy Hara G, Gould I, Endimiani A, Pardo PR, Daikos G, Hsueh PR, Mehtar S, Petrikkos G, Casellas JM, Daciuk L, Paciel D, Novelli A, Saginur R, Pryluka D, Medina J, Savio E.

J Chemother. 2013 Jun;25(3):129-40. doi: 10.1179/1973947812Y.0000000062.

PMID:
23783137
17.

Challenges in the research ethics review of cluster randomized trials: international survey of investigators.

Chaudhry SH, Brehaut JC, Grimshaw JM, Weijer C, Boruch R, Donner A, Eccles MP, McRae AD, Saginur R, Skea ZC, Zwarenstein M, Taljaard M.

Clin Trials. 2013 Apr;10(2):257-68. doi: 10.1177/1740774513475530.

PMID:
23539109
18.

Research recruitment practices and critically ill patients. A multicenter, cross-sectional study (the Consent Study).

Burns KE, Zubrinich C, Tan W, Raptis S, Xiong W, Smith O, McDonald E, Marshall JC, Saginur R, Heslegrave R, Rubenfeld G, Cook DJ; Canadian Critical Care Trials Group.

Am J Respir Crit Care Med. 2013 Jun 1;187(11):1212-8. doi: 10.1164/rccm.201208-1537OC.

PMID:
23525935
19.

Skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA): an affliction of the underclass.

Vayalumkal JV, Suh KN, Toye B, Ramotar K, Saginur R, Roth VR.

CJEM. 2012 Nov;14(6):335-43.

PMID:
23131480
20.

What is the role and authority of gatekeepers in cluster randomized trials in health research?

Gallo A, Weijer C, White A, Grimshaw JM, Boruch R, Brehaut JC, Donner A, Eccles MP, McRae AD, Saginur R, Zwarenstein M, Taljaard M.

Trials. 2012 Jul 26;13:116. doi: 10.1186/1745-6215-13-116.

21.

Informed consent documents do not encourage good-quality decision making.

Brehaut JC, Carroll K, Elwyn G, Saginur R, Kimmelman J, Shojania K, Syrowatka A, Nguyen T, Hoe E, Fergusson D.

J Clin Epidemiol. 2012 Jul;65(7):708-24. doi: 10.1016/j.jclinepi.2012.01.004. Epub 2012 Apr 25.

PMID:
22537428
22.

When is informed consent required in cluster randomized trials in health research?

McRae AD, Weijer C, Binik A, Grimshaw JM, Boruch R, Brehaut JC, Donner A, Eccles MP, Saginur R, White A, Taljaard M.

Trials. 2011 Sep 9;12:202. doi: 10.1186/1745-6215-12-202.

23.

Who is the research subject in cluster randomized trials in health research?

McRae AD, Weijer C, Binik A, White A, Grimshaw JM, Boruch R, Brehaut JC, Donner A, Eccles MP, Saginur R, Zwarenstein M, Taljaard M.

Trials. 2011 Jul 26;12:183. doi: 10.1186/1745-6215-12-183.

24.

Does clinical equipoise apply to cluster randomized trials in health research?

Binik A, Weijer C, McRae AD, Grimshaw JM, Boruch R, Brehaut JC, Donner A, Eccles MP, Saginur R, Taljaard M, Zwarenstein M.

Trials. 2011 May 11;12:118. doi: 10.1186/1745-6215-12-118.

25.

Inadequate reporting of research ethics review and informed consent in cluster randomised trials: review of random sample of published trials.

Taljaard M, McRae AD, Weijer C, Bennett C, Dixon S, Taleban J, Skea Z, Eccles MP, Brehaut JC, Donner A, Saginur R, Boruch RF, Grimshaw JM.

BMJ. 2011 May 11;342:d2496. doi: 10.1136/bmj.d2496. Review.

26.

Ethical issues posed by cluster randomized trials in health research.

Weijer C, Grimshaw JM, Taljaard M, Binik A, Boruch R, Brehaut JC, Donner A, Eccles MP, Gallo A, McRae AD, Saginur R, Zwarenstein M.

Trials. 2011 Apr 20;12:100. doi: 10.1186/1745-6215-12-100.

27.

Using decision aids may improve informed consent for research.

Brehaut JC, Fergusson DA, Kimmelman J, Shojania KG, Saginur R, Elwyn G.

Contemp Clin Trials. 2010 May;31(3):218-20. doi: 10.1016/j.cct.2010.02.002. Epub 2010 Feb 13.

PMID:
20156597
28.

Research ethics and infection control.

Saginur R.

Clin Infect Dis. 2009 Oct 15;49(8):1254-8. doi: 10.1086/605666. Review.

PMID:
19757994
29.

Ethical and policy issues in cluster randomized trials: rationale and design of a mixed methods research study.

Taljaard M, Weijer C, Grimshaw JM, Belle Brown J, Binik A, Boruch R, Brehaut JC, Chaudhry SH, Eccles MP, McRae A, Saginur R, Zwarenstein M, Donner A.

Trials. 2009 Jul 28;10:61. doi: 10.1186/1745-6215-10-61.

30.

Informed consent documentation necessary but not sufficient.

Brehaut JC, Saginur R, Elwyn G.

Contemp Clin Trials. 2009 Sep;30(5):388-9. doi: 10.1016/j.cct.2009.05.006. Epub 2009 Jun 17. No abstract available.

PMID:
19539782
31.

Research ethics review: do it once and do it well.

H├ębert P, Saginur R.

CMAJ. 2009 Mar 17;180(6):597-8. doi: 10.1503/cmaj.090172. English, French. No abstract available.

32.

Whipple's disease with constrictive pericarditis: a rare disease with a rare presentation.

Iqbal T, Karovitch A, Veinot J, Saginur R, Beauchesne L.

Can J Cardiol. 2009 Mar;25(3):e89-91.

33.

A retrospective analysis of biofilm antibiotic susceptibility testing: a better predictor of clinical response in cystic fibrosis exacerbations.

Keays T, Ferris W, Vandemheen KL, Chan F, Yeung SW, Mah TF, Ramotar K, Saginur R, Aaron SD.

J Cyst Fibros. 2009 Mar;8(2):122-7. doi: 10.1016/j.jcf.2008.10.005. Epub 2008 Dec 7.

34.

Staphylococcus aureus bacteraemia of unknown primary source: where do we stand?

Saginur R, Suh KN.

Int J Antimicrob Agents. 2008 Nov;32 Suppl 1:S21-5. doi: 10.1016/j.ijantimicag.2008.06.008. Epub 2008 Aug 30. Review.

PMID:
18757183
35.

Can patient decision aids help people make good decisions about participating in clinical trials? A study protocol.

Brehaut JC, Lott A, Fergusson DA, Shojania KG, Kimmelman J, Saginur R.

Implement Sci. 2008 Jul 23;3:38. doi: 10.1186/1748-5908-3-38.

36.

Ontario Cancer Research Ethics Board: lessons learned from developing a multicenter regional institutional review board.

Saginur R, Dent SF, Schwartz L, Heslegrave R, Stacey S, Manzo J.

J Clin Oncol. 2008 Mar 20;26(9):1479-82. doi: 10.1200/JCO.2007.12.6441.

PMID:
18349399
37.

Home-based intermediate care program vs hospitalization: Cost comparison study.

Armstrong CD, Hogg WE, Lemelin J, Dahrouge S, Martin C, Viner GS, Saginur R.

Can Fam Physician. 2008 Jan;54(1):66-73.

38.

Patient, informal caregiver and care provider acceptance of a hospital in the home program in Ontario, Canada.

Lemelin J, Hogg WE, Dahrouge S, Armstrong CD, Martin CM, Zhang W, Dusseault JA, Parsons-Nicota J, Saginur R, Viner G.

BMC Health Serv Res. 2007 Aug 17;7:130.

39.

Promoting best practices for control of respiratory infections: collaboration between primary care and public health services.

Hogg W, Huston P, Martin C, Saginur R, Newbury A, Vilis E, Soto E.

Can Fam Physician. 2006 Sep;52(9):1110-1.

40.

Multiple combination bactericidal testing of staphylococcal biofilms from implant-associated infections.

Saginur R, Stdenis M, Ferris W, Aaron SD, Chan F, Lee C, Ramotar K.

Antimicrob Agents Chemother. 2006 Jan;50(1):55-61.

41.

Sputum versus bronchoscopy for diagnosis of Pseudomonas aeruginosa biofilms in cystic fibrosis.

Aaron SD, Kottachchi D, Ferris WJ, Vandemheen KL, St Denis ML, Plouffe A, Doucette SP, Saginur R, Chan FT, Ramotar K.

Eur Respir J. 2004 Oct;24(4):631-7.

42.

Adult cystic fibrosis exacerbations and new strains of Pseudomonas aeruginosa.

Aaron SD, Ramotar K, Ferris W, Vandemheen K, Saginur R, Tullis E, Haase D, Kottachchi D, St Denis M, Chan F.

Am J Respir Crit Care Med. 2004 Apr 1;169(7):811-5. Epub 2003 Dec 11.

PMID:
14670805
43.
44.

Transmission of hepatitis C in a pharmacologic study.

Saginur R, Nixon J, Devries B, Bruce N, Carruthers C, Scully L, Berger R, Leech J, Nicolle L, Mackenzie A.

Infect Control Hosp Epidemiol. 2001 Nov;22(11):697-700.

PMID:
11842990
45.

Severe group a streptococcal soft-tissue infections in Ontario: 1992-1996.

Sharkawy A, Low DE, Saginur R, Gregson D, Schwartz B, Jessamine P, Green K, McGeer A; Ontario Group A Streptococcal Study Group.

Clin Infect Dis. 2002 Feb 15;34(4):454-60. Epub 2002 Jan 7.

PMID:
11797171
46.

Barriers to the effective management of respiratory tract infections in the community.

Saginur R.

Infection. 2001 Dec;29 Suppl 2:3-10. Review.

PMID:
11785853
47.

Comparative efficacy of teicoplanin and cefazolin for cardiac operation prophylaxis in 3027 patients. The ESPRIT Group.

Saginur R, Croteau D, Bergeron MG.

J Thorac Cardiovasc Surg. 2000 Dec;120(6):1120-30.

48.

Treatment of community-acquired pneumonia in the elderly: the role of cefepime, a fourth-generation cephalosporin.

Grossman RF, Campbell DA, Landis SJ, Garber GE, Murray G, Stiver HG, Saginur R, McIvor RA, Laforge J, Rotstein C, Dubois J, Rivard M, Boulerice F.

J Antimicrob Chemother. 1999 Apr;43(4):549-54.

PMID:
10350385
49.

Aortitis with multiple aneurysms mimicking infective endocarditis.

Veinot JP, Lorimer JW, Walley VM, Turek M, Saginur R, Rubens F.

Can J Cardiol. 1999 Jan;15(1):105-9.

PMID:
10024866
50.

Group B streptococcal necrotizing fasciitis and streptococcal toxic shock-like syndrome in adults.

Gardam MA, Low DE, Saginur R, Miller MA.

Arch Intern Med. 1998 Aug 10-24;158(15):1704-8. Review.

PMID:
9701105

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