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Items: 31

1.

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair.

Ferraro B, Leoni G, Hinkel R, Ormanns S, Paulin N, Ortega-Gomez A, Viola JR, de Jong R, Bongiovanni D, Bozoglu T, Maas SL, D'Amico M, Kessler T, Zeller T, Hristov M, Reutelingsperger C, Sager HB, Döring Y, Nahrendorf M, Kupatt C, Soehnlein O.

J Am Coll Cardiol. 2019 Jun 18;73(23):2990-3002. doi: 10.1016/j.jacc.2019.03.503.

2.

Time-of-day at symptom onset was not associated with infarct size and long-term prognosis in patients with ST-segment elevation myocardial infarction.

Sager HB, Husser O, Steffens S, Laugwitz KL, Schunkert H, Kastrati A, Ndrepepa G, Kessler T.

J Transl Med. 2019 May 29;17(1):180. doi: 10.1186/s12967-019-1934-z.

3.

Association of the coronary artery disease risk gene GUCY1A3 with ischaemic events after coronary intervention.

Kessler T, Wolf B, Eriksson N, Kofink D, Mahmoodi BK, Rai H, Tragante V, Åkerblom A, Becker RC, Bernlochner I, Bopp R, James S, Katus HA, Mayer K, Munz M, Nordio F, O'Donoghue ML, Sager HB, Sibbing D, Solakov L, Storey RF, Wobst J, Asselbergs FW, Byrne RA, Erdmann J, Koenig W, Laugwitz KL, Ten Berg JM, Wallentin L, Kastrati A, Schunkert H.

Cardiovasc Res. 2019 Aug 1;115(10):1512-1518. doi: 10.1093/cvr/cvz015.

PMID:
30768153
4.

Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 68Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques.

Varasteh Z, Mohanta S, Li Y, López Armbruster N, Braeuer M, Nekolla SG, Habenicht A, Sager HB, Raes G, Weber W, Hernot S, Schwaiger M.

EJNMMI Res. 2019 Jan 21;9(1):5. doi: 10.1186/s13550-019-0474-0.

5.

Management of hypercalcaemia-induced heart failure using mechanical circulatory support.

Knoll K, Kurowski V, Schunkert H, Sager HB.

Eur J Cardiothorac Surg. 2018 Oct 1;54(4):784-785. doi: 10.1093/ejcts/ezy139.

PMID:
29617917
6.

Cardiac macrophages promote diastolic dysfunction.

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M.

J Exp Med. 2018 Feb 5;215(2):423-440. doi: 10.1084/jem.20171274. Epub 2018 Jan 16.

7.

Acute inflammation and long-term cardiovascular risk: Identifying an unrecognised vulnerable gap.

Sager HB, Koenig W.

Eur J Prev Cardiol. 2017 Dec;24(18):1956-1957. doi: 10.1177/2047487317736869. Epub 2017 Oct 19. No abstract available.

PMID:
29048207
8.

Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus.

Kessler T, Wobst J, Wolf B, Eckhold J, Vilne B, Hollstein R, von Ameln S, Dang TA, Sager HB, Moritz Rumpf P, Aherrahrou R, Kastrati A, Björkegren JLM, Erdmann J, Lusis AJ, Civelek M, Kaiser FJ, Schunkert H.

Circulation. 2017 Aug 1;136(5):476-489. doi: 10.1161/CIRCULATIONAHA.116.024152. Epub 2017 May 9.

9.

Monocytes and macrophages in cardiac injury and repair.

Sager HB, Kessler T, Schunkert H.

J Thorac Dis. 2017 Mar;9(Suppl 1):S30-S35. doi: 10.21037/jtd.2016.11.17. Review.

10.

Macrophages Facilitate Electrical Conduction in the Heart.

Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M.

Cell. 2017 Apr 20;169(3):510-522.e20. doi: 10.1016/j.cell.2017.03.050.

11.

Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.

Sager HB, Hulsmans M, Lavine KJ, Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M.

Circ Res. 2016 Sep 16;119(7):853-64. doi: 10.1161/CIRCRESAHA.116.309001. Epub 2016 Jul 21.

12.

Stimulators of the soluble guanylyl cyclase: promising functional insights from rare coding atherosclerosis-related GUCY1A3 variants.

Wobst J, von Ameln S, Wolf B, Wierer M, Dang TA, Sager HB, Tennstedt S, Hengstenberg C, Koesling D, Friebe A, Braun SL, Erdmann J, Schunkert H, Kessler T.

Basic Res Cardiol. 2016 Jul;111(4):51. doi: 10.1007/s00395-016-0570-5. Epub 2016 Jun 24.

PMID:
27342234
13.

RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction.

Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, Xing Y, Shaw TE, Libby P, Langer R, Weissleder R, Swirski FK, Anderson DG, Nahrendorf M.

Sci Transl Med. 2016 Jun 8;8(342):342ra80. doi: 10.1126/scitranslmed.aaf1435.

14.

Inflammation: a trigger for acute coronary syndrome.

Sager HB, Nahrendorf M.

Q J Nucl Med Mol Imaging. 2016 Sep;60(3):185-93. Epub 2016 Jun 7. Review.

15.

Serum microRNA-1233 is a specific biomarker for diagnosing acute pulmonary embolism.

Kessler T, Erdmann J, Vilne B, Bruse P, Kurowski V, Diemert P, Schunkert H, Sager HB.

J Transl Med. 2016 May 5;14(1):120. doi: 10.1186/s12967-016-0886-9.

16.

Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.

Sager HB, Heidt T, Hulsmans M, Dutta P, Courties G, Sebas M, Wojtkiewicz GR, Tricot B, Iwamoto Y, Sun Y, Weissleder R, Libby P, Swirski FK, Nahrendorf M.

Circulation. 2015 Nov 17;132(20):1880-90. doi: 10.1161/CIRCULATIONAHA.115.016160. Epub 2015 Sep 10.

17.

Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells.

Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M.

Cell Stem Cell. 2015 May 7;16(5):477-87. doi: 10.1016/j.stem.2015.04.008.

18.

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.

Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M.

J Exp Med. 2015 Apr 6;212(4):497-512. doi: 10.1084/jem.20141642. Epub 2015 Mar 23.

19.

Ischemic stroke activates hematopoietic bone marrow stem cells.

Courties G, Herisson F, Sager HB, Heidt T, Ye Y, Wei Y, Sun Y, Severe N, Dutta P, Scharff J, Scadden DT, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M.

Circ Res. 2015 Jan 30;116(3):407-17. doi: 10.1161/CIRCRESAHA.116.305207. Epub 2014 Oct 31.

20.

Chronic variable stress activates hematopoietic stem cells.

Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M.

Nat Med. 2014 Jul;20(7):754-758. doi: 10.1038/nm.3589. Epub 2014 Jun 22.

21.

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight.

Dahlman JE, Barnes C, Khan O, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, Jiang S, Seedorf D, Dave A, Sandu KS, Webber MJ, Novobrantseva T, Ruda VM, Lytton-Jean AKR, Levins CG, Kalish B, Mudge DK, Perez M, Abezgauz L, Dutta P, Smith L, Charisse K, Kieran MW, Fitzgerald K, Nahrendorf M, Danino D, Tuder RM, von Andrian UH, Akinc A, Schroeder A, Panigrahy D, Kotelianski V, Langer R, Anderson DG.

Nat Nanotechnol. 2014 Aug;9(8):648-655. doi: 10.1038/nnano.2014.84. Epub 2014 May 11.

22.

Differential contribution of monocytes to heart macrophages in steady-state and after myocardial infarction.

Heidt T, Courties G, Dutta P, Sager HB, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Laan AM, Swirski FK, Weissleder R, Nahrendorf M.

Circ Res. 2014 Jul 7;115(2):284-95. doi: 10.1161/CIRCRESAHA.115.303567. Epub 2014 May 1. Erratum in: Circ Res. 2014 Dec 5;115(12):e95. van der Lahn, Anja M [corrected to van der Laan, Anja M].

23.

In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.

Courties G, Heidt T, Sebas M, Iwamoto Y, Jeon D, Truelove J, Tricot B, Wojtkiewicz G, Dutta P, Sager HB, Borodovsky A, Novobrantseva T, Klebanov B, Fitzgerald K, Anderson DG, Libby P, Swirski FK, Weissleder R, Nahrendorf M.

J Am Coll Cardiol. 2014 Apr 22;63(15):1556-66. doi: 10.1016/j.jacc.2013.11.023. Epub 2013 Dec 18.

24.

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.

Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB, Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde S, Rossmann H, Diemert P, Cupples LA, Perret C, Erdmann J, Stark K, Kleber ME, Epstein SE, Voight BF, Kuulasmaa K, Li M, Schäfer AS, Klopp N, Braund PS, Sager HB, Demissie S, Proust C, König IR, Wichmann HE, Reinhard W, Hoffmann MM, Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu L, El Mokthari NE, Thompson JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W, Amouyel P, Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander K, Hall AS, Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H, Schrezenmeir J, Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T, Schreiber S, Bis JC, Altshuler D, Kavousi M, Witteman JC, Uitterlinden AG, Hofman A, Folsom AR, Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP, O'Donnell CJ, Samani NJ, Schunkert H, Cambien F, Lackner KJ, Tiret L, Salomaa V, Munzel T, Ziegler A, Blankenberg S.

Circ Cardiovasc Genet. 2011 Aug 1;4(4):403-12. doi: 10.1161/CIRCGENETICS.110.958728. Epub 2011 May 23.

25.

Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.

Erdmann J, Willenborg C, Nahrstaedt J, Preuss M, König IR, Baumert J, Linsel-Nitschke P, Gieger C, Tennstedt S, Belcredi P, Aherrahrou Z, Klopp N, Loley C, Stark K, Hengstenberg C, Bruse P, Freyer J, Wagner AK, Medack A, Lieb W, Grosshennig A, Sager HB, Reinhardt A, Schäfer A, Schreiber S, El Mokhtari NE, Raaz-Schrauder D, Illig T, Garlichs CD, Ekici AB, Reis A, Schrezenmeir J, Rubin D, Ziegler A, Wichmann HE, Doering A, Meisinger C, Meitinger T, Peters A, Schunkert H.

Eur Heart J. 2011 Jan;32(2):158-68. doi: 10.1093/eurheartj/ehq405. Epub 2010 Nov 18.

PMID:
21088011
26.

Recurrent mid-ventricular Tako-Tsubo cardiomyopathy: three episodes of a uniform cardiac response to varying stressors.

Sager HB, Schunkert H, Kurowski V.

Int J Cardiol. 2011 Oct 6;152(1):e22-4. doi: 10.1016/j.ijcard.2010.09.081. Epub 2010 Oct 20. No abstract available.

PMID:
20965597
27.

Temporal patterns of blood flow and nitric oxide synthase expression affect macrophage accumulation and proliferation during collateral growth.

Sager HB, Middendorff R, Rauche K, Weil J, Lieb W, Schunkert H, Ito WD.

J Angiogenes Res. 2010 Sep 16;2:18. doi: 10.1186/2040-2384-2-18.

28.

Lethal hemorrhage caused by aortoesophageal fistula secondary to stent-graft repair of the thoracic aorta.

Sager HB, Wellhöner P, Wermelt JA, Schunkert H, Kurowski V.

Cardiovasc Intervent Radiol. 2011 Feb;34 Suppl 2:S60-3. doi: 10.1007/s00270-010-9844-8.

PMID:
20390273
29.

Physicians' perception of guideline-recommended low-density lipoprotein target values: characteristics of misclassified patients.

Sager HB, Linsel-Nitschke P, Mayer B, Lieb W, Franzel B, Elsasser U, Schunkert H.

Eur Heart J. 2010 May;31(10):1266-73. doi: 10.1093/eurheartj/ehq026. Epub 2010 Mar 10.

PMID:
20219745
30.

Expression of carcinoembryonic antigen-related cell adhesion molecule 1 in acute rejection of human renal allografts.

Sager HB, Ergun S, Hartmann A, Hoffmann U, Krämer BK, Mihatsch MJ, Weil J.

Transplant Proc. 2009 Jun;41(5):1536-40. doi: 10.1016/j.transproceed.2009.03.059.

PMID:
19545674
31.

Tako-tsubo cardiomyopathy mimicking acute aortic dissection: a case report.

Sager HB, Schunkert H, Kurowski V.

Int J Cardiol. 2010 Nov 19;145(2):e68-e69. doi: 10.1016/j.ijcard.2008.12.157. Epub 2009 Jan 30.

PMID:
19185360

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