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Items: 1 to 50 of 96

1.

Rapid clinical mutational testing of KRAS, BRAF and EGFR: a prospective comparative analysis of the Idylla technique with high-throughput next-generation sequencing.

Van Haele M, Vander Borght S, Ceulemans A, Wieërs M, Metsu S, Sagaert X, Weynand B.

J Clin Pathol. 2019 Jul 11. pii: jclinpath-2019-205970. doi: 10.1136/jclinpath-2019-205970. [Epub ahead of print]

PMID:
31296605
2.

Correction to: Secondary B-cell lymphoma associated with the Epstein-Barr virus in chronic lymphocytic leukemia patients.

Morscio J, Bittoun E, Volders N, Lurquin E, Wlodarska I, Gheysens O, Vandenberghe P, Verhoef G, Demaerel P, Dierickx D, Sagaert X, Janssens A, Tousseyn T.

J Hematop. 2018 May 4;11(2):65. doi: 10.1007/s12308-018-0323-5. eCollection 2018 Jun.

3.

MALT Lymphoma as a Model of Chronic Inflammation-Induced Gastric Tumor Development.

Marcelis L, Tousseyn T, Sagaert X.

Curr Top Microbiol Immunol. 2019;421:77-106. doi: 10.1007/978-3-030-15138-6_4. Review.

PMID:
31123886
4.

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas.

Pascual M, Mena-Varas M, Robles EF, Garcia-Barchino MJ, Panizo C, Hervas-Stubbs S, Alignani D, Sagardoy A, Martinez-Ferrandis JI, Bunting KL, Meier S, Sagaert X, Bagnara D, Guruceaga E, Blanco O, Celay J, Martínez-Baztan A, Casares N, Lasarte JJ, MacCarthy T, Melnick A, Martinez-Climent JA, Roa S.

Blood. 2019 May 30;133(22):2401-2412. doi: 10.1182/blood.2018889931. Epub 2019 Apr 11.

PMID:
30975638
5.

Delayed bleeding of the Transplant Duodenum After Simultaneous Kidney Pancreas Transplantation: Case Series.

Van Mellaert A, Gillard P, Jochmans I, Demedts I, Sagaert X, Naesens M, Monbaliu D, Kuypers D, Pirenne J, Sprangers B.

Transplantation. 2019 Apr 1. doi: 10.1097/TP.0000000000002718. [Epub ahead of print]

PMID:
30946219
6.

Solid Tumor-Induced Immune Regulation Alters the GvHD/GvT Paradigm after Allogenic Bone Marrow Transplantation.

Dang N, Lin Y, Rutgeerts O, Sagaert X, Billiau AD, Waer M, Sprangers B.

Cancer Res. 2019 May 15;79(10):2709-2721. doi: 10.1158/0008-5472.CAN-18-3143. Epub 2019 Apr 1.

PMID:
30936086
7.

Gastric Tumoral Melanosis: a Rare Manifestation of Successfully Treated Malignant Melanoma.

Bronswijk M, Sagaert X, Bechter OE.

Clin Gastroenterol Hepatol. 2019 Feb 8. pii: S1542-3565(19)30144-2. doi: 10.1016/j.cgh.2019.02.006. [Epub ahead of print] No abstract available.

PMID:
30743010
8.

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.

Kalucka J, Bierhansl L, Conchinha NV, Missiaen R, Elia I, Brüning U, Scheinok S, Treps L, Cantelmo AR, Dubois C, de Zeeuw P, Goveia J, Zecchin A, Taverna F, Morales-Rodriguez F, Brajic A, Conradi LC, Schoors S, Harjes U, Vriens K, Pilz GA, Chen R, Cubbon R, Thienpont B, Cruys B, Wong BW, Ghesquière B, Dewerchin M, De Bock K, Sagaert X, Jessberger S, Jones EAV, Gallez B, Lambrechts D, Mazzone M, Eelen G, Li X, Fendt SM, Carmeliet P.

Cell Metab. 2018 Dec 4;28(6):881-894.e13. doi: 10.1016/j.cmet.2018.07.016. Epub 2018 Aug 23.

9.

ypT0N+: the unusual patient with pathological complete tumor response but with residual lymph node disease after neoadjuvant chemoradiation for esophageal cancer, what's up?

Depypere LP, Vervloet G, Lerut T, Moons J, De Hertogh G, Sagaert X, Coosemans W, Van Veer H, Nafteux PR.

J Thorac Dis. 2018 May;10(5):2771-2778. doi: 10.21037/jtd.2018.04.136.

10.

Other immunomodulatory agent-related lymphoproliferative diseases: a single-center series of 72 biopsy-confirmed cases.

Marcelis L, Berghen C, De Zutter A, Biesemans P, Vandenberghe P, Verhoef G, Gheysens O, Sagaert X, Dierickx D, Tousseyn T.

Mod Pathol. 2018 Sep;31(9):1457-1469. doi: 10.1038/s41379-018-0054-2. Epub 2018 May 15.

11.

Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukaemia.

García-Barchino MJ, Sarasquete ME, Panizo C, Morscio J, Martinez A, Alcoceba M, Fresquet V, Gonzalez-Farre B, Paiva B, Young KH, Robles EF, Roa S, Celay J, Larrayoz M, Rossi D, Gaidano G, Montes-Moreno S, Piris MA, Balanzategui A, Jimenez C, Rodriguez I, Calasanz MJ, Larrayoz MJ, Segura V, Garcia-Muñoz R, Rabasa MP, Yi S, Li J, Zhang M, Xu-Monette ZY, Puig-Moron N, Orfao A, Böttcher S, Hernandez-Rivas JM, Miguel JS, Prosper F, Tousseyn T, Sagaert X, Gonzalez M, Martinez-Climent JA.

J Pathol. 2018 May;245(1):61-73. doi: 10.1002/path.5060. Epub 2018 Mar 30.

PMID:
29464716
12.

Tumor Heterogeneity in Colorectal Cancer: What Do We Know So Far?

Sagaert X, Vanstapel A, Verbeek S.

Pathobiology. 2018;85(1-2):72-84. doi: 10.1159/000486721. Epub 2018 Feb 7. Review.

13.

Cytoreductive surgery and Hyperthermic intra-operative peritoneal chemotherapy with Cisplatin for gastric peritoneal Carcinomatosis Monocentric phase-2 nonrandomized prospective clinical trial.

Topal B, Demey K, Topal H, Jaekers J, Van Cutsem E, Vandecaveye V, Sagaert X, Prenen H.

BMC Cancer. 2017 Nov 17;17(1):771. doi: 10.1186/s12885-017-3730-6.

14.

Locally Advanced Colorectal Cancer: True Peritoneal Tumor Penetration is Associated with Peritoneal Metastases.

Klaver CEL, van Huijgevoort NCM, de Buck van Overstraeten A, Wolthuis AM, Tanis PJ, van der Bilt JDW, Sagaert X, D'Hoore A.

Ann Surg Oncol. 2018 Jan;25(1):212-220. doi: 10.1245/s10434-017-6037-6. Epub 2017 Oct 26.

15.

PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development.

Sents W, Meeusen B, Kalev P, Radaelli E, Sagaert X, Miermans E, Haesen D, Lambrecht C, Dewerchin M, Carmeliet P, Westermarck J, Sablina A, Janssens V.

Cancer Res. 2017 Dec 15;77(24):6825-6837. doi: 10.1158/0008-5472.CAN-16-2911. Epub 2017 Oct 18.

16.

Prognostic value of the circumferential resection margin and its definitions in esophageal cancer patients after neoadjuvant chemoradiotherapy.

Depypere L, Moons J, Lerut T, De Hertogh G, Peters C, Sagaert X, Coosemans W, Van Veer H, Nafteux P.

Dis Esophagus. 2018 Feb 1;31(2). doi: 10.1093/dote/dox117.

PMID:
29036407
17.

Loss of protein phosphatase 2A regulatory subunit B56δ promotes spontaneous tumorigenesis in vivo.

Lambrecht C, Libbrecht L, Sagaert X, Pauwels P, Hoorne Y, Crowther J, Louis JV, Sents W, Sablina A, Janssens V.

Oncogene. 2018 Jan 25;37(4):544-552. doi: 10.1038/onc.2017.350. Epub 2017 Oct 2.

PMID:
28967903
18.

Quantitative imaging outperforms molecular markers when predicting response to chemoradiotherapy for rectal cancer.

Joye I, Debucquoy A, Deroose CM, Vandecaveye V, Cutsem EV, Wolthuis A, D'Hoore A, Sagaert X, Zhou M, Gevaert O, Haustermans K.

Radiother Oncol. 2017 Jul;124(1):104-109. doi: 10.1016/j.radonc.2017.06.013. Epub 2017 Jun 21.

19.

Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.

De Smet F, Saiz Rubio M, Hompes D, Naus E, De Baets G, Langenberg T, Hipp MS, Houben B, Claes F, Charbonneau S, Delgado Blanco J, Plaisance S, Ramkissoon S, Ramkissoon L, Simons C, van den Brandt P, Weijenberg M, Van England M, Lambrechts S, Amant F, D'Hoore A, Ligon KL, Sagaert X, Schymkowitz J, Rousseau F.

J Pathol. 2017 May;242(1):24-38. doi: 10.1002/path.4872. Epub 2017 Mar 23.

PMID:
28035683
20.

Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching.

De Smedt L, Palmans S, Andel D, Govaere O, Boeckx B, Smeets D, Galle E, Wouters J, Barras D, Suffiotti M, Dekervel J, Tousseyn T, De Hertogh G, Prenen H, Tejpar S, Lambrechts D, Sagaert X.

Br J Cancer. 2017 Jan 3;116(1):58-65. doi: 10.1038/bjc.2016.382. Epub 2016 Nov 24.

21.

Oesophageal biopsies are insufficient to predict final histology after endoscopic resection in early Barrett's neoplasia.

Werbrouck E, De Hertogh G, Sagaert X, Coremans G, Willekens H, Demedts I, Bisschops R.

United European Gastroenterol J. 2016 Oct;4(5):663-668. Epub 2016 Jan 6.

22.

A Simplified Geboes Score for Ulcerative Colitis.

Jauregui-Amezaga A, Geerits A, Das Y, Lemmens B, Sagaert X, Bessissow T, Lobatón T, Ferrante M, Van Assche G, Bisschops R, Geboes K, De Hertogh G, Vermeire S.

J Crohns Colitis. 2017 Mar 1;11(3):305-313. doi: 10.1093/ecco-jcc/jjw154.

PMID:
27571771
23.

Neoadjuvant chemoradiation treatment followed by surgery for esophageal cancer: there is much more than the mandard tumor regression score.

Depypere L, Moons J, Lerut T, De Hertogh G, Sagaert X, Coosemans W, Van Veer H, Renders A, Nafteux P.

Acta Chir Belg. 2016 Jun;116(3):149-155. doi: 10.1080/00015458.2016.1212500. Epub 2016 Jul 29.

PMID:
27472306
24.

Submucosal Plexitis as a Predictive Factor for Postoperative Endoscopic Recurrence in Patients with Crohn's Disease Undergoing a Resection with Ileocolonic Anastomosis: Results from a Prospective Single-centre Study.

Lemmens B, de Buck van Overstraeten A, Arijs I, Sagaert X, Van Assche G, Vermeire S, Tertychnyy A, Geboes K, Wolthuis A, D'Hoore A, De Hertogh G, Ferrante M.

J Crohns Colitis. 2017 Feb;11(2):212-220. doi: 10.1093/ecco-jcc/jjw135. Epub 2016 Jul 27.

PMID:
27466173
25.

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics.

Robles EF, Mena-Varas M, Barrio L, Merino-Cortes SV, Balogh P, Du MQ, Akasaka T, Parker A, Roa S, Panizo C, Martin-Guerrero I, Siebert R, Segura V, Agirre X, Macri-Pellizeri L, Aldaz B, Vilas-Zornoza A, Zhang S, Moody S, Calasanz MJ, Tousseyn T, Broccardo C, Brousset P, Campos-Sanchez E, Cobaleda C, Sanchez-Garcia I, Fernandez-Luna JL, Garcia-Muñoz R, Pena E, Bellosillo B, Salar A, Baptista MJ, Hernandez-Rivas JM, Gonzalez M, Terol MJ, Climent J, Ferrandez A, Sagaert X, Melnick AM, Prosper F, Oscier DG, Carrasco YR, Dyer MJ, Martinez-Climent JA.

Nat Commun. 2016 Jun 14;7:11889. doi: 10.1038/ncomms11889.

26.

Secondary B-cell lymphoma associated with the Epstein-Barr virus in chronic lymphocytic leukemia patients.

Morscio J, Bittoun E, Volders N, Lurquin E, Wlodarska I, Gheysens O, Vandenberghe P, Verhoef G, Demaerel P, Dierickx D, Sagaert X, Janssens A, Tousseyn T.

J Hematop. 2016 May 21;9:113-120. doi: 10.1007/s12308-016-0273-8. eCollection 2016. Erratum in: J Hematop. 2018 May 4;11(2):65.

27.

Gastric cancer.

Van Cutsem E, Sagaert X, Topal B, Haustermans K, Prenen H.

Lancet. 2016 Nov 26;388(10060):2654-2664. doi: 10.1016/S0140-6736(16)30354-3. Epub 2016 May 5. Review.

PMID:
27156933
28.

Can clinical factors be used as a selection tool for an organ-preserving strategy in rectal cancer?

Joye I, Debucquoy A, Fieuws S, Wolthuis A, Sagaert X, D'Hoore A, Haustermans K.

Acta Oncol. 2016 Aug;55(8):1047-52. doi: 10.3109/0284186X.2016.1167954. Epub 2016 May 4.

PMID:
27142064
29.

Detection of bone marrow involvement in newly diagnosed post-transplant lymphoproliferative disorder: (18)F-fluorodeoxyglucose positron emission tomography/computed tomography versus bone marrow biopsy.

Gheysens O, Thielemans S, Morscio J, Boeckx N, Goffin KE, Deroose CM, Sagaert X, Wlodarska I, Verhoef G, Dierickx D, Tousseyn T.

Leuk Lymphoma. 2016 Oct;57(10):2382-8. doi: 10.3109/10428194.2016.1140162. Epub 2016 Feb 8.

PMID:
26854937
30.

Comparison of multiple protein extraction buffers for GeLC-MS/MS proteomic analysis of liver and colon formalin-fixed, paraffin-embedded tissues.

Broeckx V, Boonen K, Pringels L, Sagaert X, Prenen H, Landuyt B, Schoofs L, Maes E.

Mol Biosyst. 2016 Feb;12(2):553-65. doi: 10.1039/c5mb00670h.

PMID:
26676081
31.

Yttrium-90 radioembolization for the treatment of chemorefractory colorectal liver metastases: Technical results, clinical outcome and factors potentially influencing survival.

Maleux G, Deroose C, Laenen A, Verslype C, Heye S, Haustermans K, De Hertogh G, Sagaert X, Topal B, Aerts R, Prenen H, Vanbeckevoort D, Vandecaveye V, Van Cutsem E.

Acta Oncol. 2016;55(4):486-95. doi: 10.3109/0284186X.2015.1101151. Epub 2015 Dec 1.

PMID:
26625262
32.

Tumour budding in colorectal cancer: what do we know and what can we do?

De Smedt L, Palmans S, Sagaert X.

Virchows Arch. 2016 Apr;468(4):397-408. doi: 10.1007/s00428-015-1886-5. Epub 2015 Nov 27. Review.

PMID:
26613731
33.

Expression of FOXP1 and Colorectal Cancer Prognosis.

De Smedt L, Palmans S, Govaere O, Moisse M, Boeckx B, De Hertogh G, Prenen H, Van Cutsem E, Tejpar S, Tousseyn T, Sagaert X.

Lab Med. 2015 Fall;46(4):299-311. doi: 10.1309/LM7IHV2NJI1PHMXC.

PMID:
26489674
34.

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma.

Prenen H, Smeets D, Mazzone M, Lambrechts D, Sagaert X, Sciot R, Debiec-Rychter M.

Oncotarget. 2015 Nov 3;6(34):36418-25. doi: 10.18632/oncotarget.5503.

35.

Evaluation of efficacy and safety markers in a phase II study of metastatic colorectal cancer treated with aflibercept in the first-line setting.

Lambrechts D, Thienpont B, Thuillier V, Sagaert X, Moisse M, Peuteman G, Pericay C, Folprecht G, Zalcberg J, Zilocchi C, Margherini E, Chiron M, Van Cutsem E.

Br J Cancer. 2015 Sep 29;113(7):1027-34. doi: 10.1038/bjc.2015.329. Epub 2015 Sep 10.

36.

DNA methylation profiling of non-small cell lung cancer reveals a COPD-driven immune-related signature.

Wauters E, Janssens W, Vansteenkiste J, Decaluwé H, Heulens N, Thienpont B, Zhao H, Smeets D, Sagaert X, Coolen J, Decramer M, Liston A, De Leyn P, Moisse M, Lambrechts D.

Thorax. 2015 Dec;70(12):1113-22. doi: 10.1136/thoraxjnl-2015-207288. Epub 2015 Sep 8.

PMID:
26349763
37.

Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis.

De Smedt L, Lemahieu J, Palmans S, Govaere O, Tousseyn T, Van Cutsem E, Prenen H, Tejpar S, Spaepen M, Matthijs G, Decaestecker C, Moles Lopez X, Demetter P, Salmon I, Sagaert X.

Br J Cancer. 2015 Jul 28;113(3):500-9. doi: 10.1038/bjc.2015.213. Epub 2015 Jun 11.

38.

Morphometric and quantitative immunohistochemical analysis of disease-related changes in the upper (suburothelial) lamina propria of the human bladder dome.

Gevaert T, Moles Lopez X, Sagaert X, Libbrecht L, Roskams T, Rorive S, Decaestecker C, Salmon I, De Ridder D.

PLoS One. 2015 May 14;10(5):e0127020. doi: 10.1371/journal.pone.0127020. eCollection 2015.

39.

Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial.

Verstraete M, Debucquoy A, Dekervel J, van Pelt J, Verslype C, Devos E, Chiritescu G, Dumon K, D'Hoore A, Gevaert O, Sagaert X, Van Cutsem E, Haustermans K.

Br J Cancer. 2015 Apr 14;112(8):1314-25. doi: 10.1038/bjc.2015.93. Epub 2015 Mar 17.

40.

Adenocarcinoma at the gastroesophageal junction.

Al-Haddad S, Chang AC, De Hertogh G, Grin A, Langer R, Sagaert X, Salemme M, Streutker CJ, Soucy G, Tripathi M, Upton MP, Vieth M, Villanacci V.

Ann N Y Acad Sci. 2014 Sep;1325:211-25. doi: 10.1111/nyas.12535.

41.

Therapeutic approaches to gastroesophageal junction adenocarcinomas.

Blom RL, Bogush T, Brücher BL, Chang AC, Davydov M, Dudko E, Leong T, Polotsky B, Swanson PE, van Rossum PS, Ruurda JP, Sagaert X, Tjulandin S, Schraepen MC, Sosef MN, van Hillegersberg R.

Ann N Y Acad Sci. 2014 Sep;1325:197-210. doi: 10.1111/nyas.12532.

42.

Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability.

Quimbaya M, Raspé E, Denecker G, De Craene B, Roelandt R, Declercq W, Sagaert X, De Veylder L, Berx G.

Neoplasia. 2014 Sep;16(9):694-709. doi: 10.1016/j.neo.2014.07.011.

43.

An unsuspected cause of diarrhoea and gastrointestinal bleeding during corticosteroid therapy.

Vanuytsel T, Sagaert X, Van Dijck H, Vandepitte K, Shea-Donohue T, Tack J, Van den Brande P.

Acta Gastroenterol Belg. 2014 Jun;77(2):259-61.

PMID:
25090826
44.

Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks.

Zhao H, Thienpont B, Yesilyurt BT, Moisse M, Reumers J, Coenegrachts L, Sagaert X, Schrauwen S, Smeets D, Matthijs G, Aerts S, Cools J, Metcalf A, Spurdle A; ANECS, Amant F, Lambrechts D.

Elife. 2014 Aug 1;3:e02725. doi: 10.7554/eLife.02725.

45.

Clinicopathologic comparison of plasmablastic lymphoma in HIV-positive, immunocompetent, and posttransplant patients: single-center series of 25 cases and meta-analysis of 277 reported cases.

Morscio J, Dierickx D, Nijs J, Verhoef G, Bittoun E, Vanoeteren X, Wlodarska I, Sagaert X, Tousseyn T.

Am J Surg Pathol. 2014 Jul;38(7):875-86. doi: 10.1097/PAS.0000000000000234.

PMID:
24832164
46.

Prognostic biomarkers in colorectal cancer: where do we stand?

Sagaert X.

Virchows Arch. 2014 Mar;464(3):379-91. doi: 10.1007/s00428-013-1532-z. Epub 2014 Feb 1. Review.

PMID:
24487787
47.

Hypoxia-driven gene expression is an independent prognostic factor in stage II and III colon cancer patients.

Dekervel J, Hompes D, van Malenstein H, Popovic D, Sagaert X, De Moor B, Van Cutsem E, D'Hoore A, Verslype C, van Pelt J.

Clin Cancer Res. 2014 Apr 15;20(8):2159-68. doi: 10.1158/1078-0432.CCR-13-2958. Epub 2014 Jan 31.

48.

Prevalence of Achromobacter xylosoxidans in pulmonary mucosa-associated lymphoid tissue lymphoma in different regions of Europe.

Adam P, Czapiewski P, Colak S, Kosmidis P, Tousseyn T, Sagaert X, Boudova L, Okoń K, Morresi-Hauf A, Agostinelli C, Pileri S, Pruneri G, Martinelli G, Du MQ, Fend F.

Br J Haematol. 2014 Mar;164(6):804-10. doi: 10.1111/bjh.12703. Epub 2013 Dec 23.

PMID:
24372375
49.

Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma--endpoints of a spectrum of one disease?

Hartmann S, Döring C, Jakobus C, Rengstl B, Newrzela S, Tousseyn T, Sagaert X, Ponzoni M, Facchetti F, de Wolf-Peeters C, Steidl C, Gascoyne R, Küppers R, Hansmann ML.

PLoS One. 2013 Nov 11;8(11):e78812. doi: 10.1371/journal.pone.0078812. eCollection 2013.

50.

The esophageal mucosa and submucosa: immunohistology in GERD and Barrett's esophagus.

Appelman HD, Streutker C, Vieth M, Neumann H, Neurath MF, Upton MP, Sagaert X, Wang HH, El-Zimaity H, Abraham SC, Bellizzi AM.

Ann N Y Acad Sci. 2013 Oct;1300:144-165. doi: 10.1111/nyas.12241. Review.

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