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Items: 39

1.

Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs.

Ren Y, Korom M, Truong R, Chan D, Huang SH, Kovacs CC, Benko E, Safrit JT, Lee J, Garbán H, Apps R, Goldstein H, Lynch RM, Jones RB.

J Virol. 2018 Nov 12;92(23). pii: e00895-18. doi: 10.1128/JVI.00895-18. Print 2018 Dec 1.

2.

Conventional early infant diagnosis in Lesotho from specimen collection to results usage to manage patients: Where are the bottlenecks?

Tiam A, Gill MM, Hoffman HJ, Isavwa A, Mokone M, Foso M, Safrit JT, Mofenson LM, Tylleskär T, Guay L.

PLoS One. 2017 Oct 10;12(10):e0184769. doi: 10.1371/journal.pone.0184769. eCollection 2017.

3.

Novel approaches in preclinical HIV vaccine research.

Safrit JT, Koff WC.

Curr Opin HIV AIDS. 2016 Nov;11(6):601-606. Review.

PMID:
27636502
4.

The Landscape of Targeted Immune Responses in the HIV-1 Vaccine Field.

Safrit JT, Tomaras GD, Hanke T, deCamp AC, Voronin Y.

AIDS Res Hum Retroviruses. 2016 Oct/Nov;32(10-11):944-946. Epub 2016 Jul 25. No abstract available.

5.

Status of vaccine research and development of vaccines for HIV-1.

Safrit JT, Fast PE, Gieber L, Kuipers H, Dean HJ, Koff WC.

Vaccine. 2016 Jun 3;34(26):2921-2925. doi: 10.1016/j.vaccine.2016.02.074. Epub 2016 Mar 15.

6.

HIV monoclonal antibodies: a new opportunity to further reduce mother-to-child HIV transmission.

Voronin Y, Mofenson LM, Cunningham CK, Fowler MG, Kaleebu P, McFarland EJ, Safrit JT, Graham BS, Snow W.

PLoS Med. 2014 Apr 8;11(4):e1001616. doi: 10.1371/journal.pmed.1001616. eCollection 2014 Apr.

7.

Epidemiology of HIV infection and risk in adolescents and youth.

Wilson CM, Wright PF, Safrit JT, Rudy B.

J Acquir Immune Defic Syndr. 2010 Jul;54 Suppl 1:S5-6. doi: 10.1097/QAI.0b013e3181e243a1.

8.

Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an open-label randomised trial.

Chi BH, Sinkala M, Mbewe F, Cantrell RA, Kruse G, Chintu N, Aldrovandi GM, Stringer EM, Kankasa C, Safrit JT, Stringer JS.

Lancet. 2007 Nov 17;370(9600):1698-705. Epub 2007 Nov 7. Erratum in: Lancet. 2008 Feb 23;371(9613):650.

PMID:
17997151
9.

Depletion of CD8+ cells in sooty mangabey monkeys naturally infected with simian immunodeficiency virus reveals limited role for immune control of virus replication in a natural host species.

Barry AP, Silvestri G, Safrit JT, Sumpter B, Kozyr N, McClure HM, Staprans SI, Feinberg MB.

J Immunol. 2007 Jun 15;178(12):8002-12.

10.

The maturing immune system: implications for development and testing HIV-1 vaccines for children and adolescents.

Jaspan HB, Lawn SD, Safrit JT, Bekker LG.

AIDS. 2006 Feb 28;20(4):483-94. No abstract available.

PMID:
16470112
11.

Induction of humoral immune responses following vaccination with envelope-containing, formaldehyde-treated, thermally inactivated human immunodeficiency virus type 1.

Poon B, Safrit JT, McClure H, Kitchen C, Hsu JF, Gudeman V, Petropoulos C, Wrin T, Chen IS, Grovit-Ferbas K.

J Virol. 2005 Apr;79(8):4927-35.

12.

Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein.

Staprans SI, Barry AP, Silvestri G, Safrit JT, Kozyr N, Sumpter B, Nguyen H, McClure H, Montefiori D, Cohen JI, Feinberg MB.

Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13026-31. Epub 2004 Aug 23.

13.

Priming B cell-mediated anti-HIV envelope responses by vaccination allows for the long-term control of infection in macaques exposed to a R5-tropic SHIV.

Buckner C, Gines LG, Saunders CJ, Vojtech L, Srivastava I, Gettie A, Bohm R, Blanchard J, Barnett SW, Safrit JT, Stamatatos L.

Virology. 2004 Mar 1;320(1):167-80. Erratum in: Virology. 2004 Jul 20;325(1):164.

14.

Immunoprophylaxis to prevent mother-to-child transmission of HIV-1.

Safrit JT, Ruprecht R, Ferrantelli F, Xu W, Kitabwalla M, Van Rompay K, Marthas M, Haigwood N, Mascola JR, Luzuriaga K, Jones SA, Mathieson BJ, Newell ML; Ghent IAS Working Group on HIV in Women Children.

J Acquir Immune Defic Syndr. 2004 Feb 1;35(2):169-77. Review.

PMID:
14722451
15.
16.

Visualization and quantification of T cell-mediated cytotoxicity using cell-permeable fluorogenic caspase substrates.

Liu L, Chahroudi A, Silvestri G, Wernett ME, Kaiser WJ, Safrit JT, Komoriya A, Altman JD, Packard BZ, Feinberg MB.

Nat Med. 2002 Feb;8(2):185-9.

PMID:
11821904
17.

Induction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques.

Montefiori DC, Safrit JT, Lydy SL, Barry AP, Bilska M, Vo HT, Klein M, Tartaglia J, Robinson HL, Rovinski B.

J Virol. 2001 Jul;75(13):5879-90.

18.

Identification of subdominant cytotoxic T lymphocyte epitopes encoded by autologous HIV type 1 sequences, using dendritic cell stimulation and computer-driven algorithm.

Jin X, Roberts CG, Nixon DF, Safrit JT, Zhang LQ, Huang YX, Bhardwaj N, Jesdale B, DeGroot AS, Koup RA.

AIDS Res Hum Retroviruses. 2000 Jan 1;16(1):67-76.

PMID:
10628818
19.

Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.

Jin X, Bauer DE, Tuttleton SE, Lewin S, Gettie A, Blanchard J, Irwin CE, Safrit JT, Mittler J, Weinberger L, Kostrikis LG, Zhang L, Perelson AS, Ho DD.

J Exp Med. 1999 Mar 15;189(6):991-8.

20.

Processing of HIV-1 envelope glycoprotein for class I-restricted recognition: dependence on TAP1/2 and mechanisms for cytosolic localization.

Ferris RL, Hall C, Sipsas NV, Safrit JT, Trocha A, Koup RA, Johnson RP, Siliciano RF.

J Immunol. 1999 Feb 1;162(3):1324-32.

21.

New observations on cellular immune responses to HIV and T-cell epitopes.

Gotch FM, Koup RA, Safrit JT.

AIDS. 1997;11 Suppl A:S99-107. Review. No abstract available.

PMID:
9451973
22.

CD8+ T-cell-mediated suppression of HIV replication in the first year of life: association with lower viral load and favorable early survival.

Pollack H, Zhan MX, Safrit JT, Chen SH, Rochford G, Tao PZ, Koup R, Krasinski K, Borkowsky W.

AIDS. 1997 Jan;11(1):F9-13.

PMID:
9110069
23.

Response: HIV-1 Evolution and Disease Progression.

Wolinsky SM, Kunstman KJ, Safrit JT, Koup RA, Neumann AU, Korber BT.

Science. 1996 Nov 8;274(5289):1010-1. No abstract available.

PMID:
17798610
24.

Defining antibody protection against HIV-1 transmission in Hu-PBL-SCID mice.

Koup RA, Safrit JT, Weir R, Gauduin MC.

Semin Immunol. 1996 Aug;8(4):263-8. Review.

PMID:
8883150
25.

Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection.

Wolinsky SM, Korber BT, Neumann AU, Daniels M, Kunstman KJ, Whetsell AJ, Furtado MR, Cao Y, Ho DD, Safrit JT.

Science. 1996 Apr 26;272(5261):537-42.

PMID:
8614801
26.

The CD4 Loss in AIDS Patients is not Immunopathologically Mediated.

Safrit JT, Koup RA.

Rev Med Virol. 1996 Mar;6(1):13-16. No abstract available.

PMID:
10398442
27.

The immunology of primary HIV infection: which immune responses control HIV replication?

Safrit JT, Koup RA.

Curr Opin Immunol. 1995 Aug;7(4):456-61. Review.

PMID:
7495508
28.
29.

Pre- and postexposure protection against human immunodeficiency virus type 1 infection mediated by a monoclonal antibody.

Gauduin MC, Safrit JT, Weir R, Fung MS, Koup RA.

J Infect Dis. 1995 May;171(5):1203-9.

PMID:
7751695
30.
31.

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome.

Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, Borkowsky W, Farthing C, Ho DD.

J Virol. 1994 Jul;68(7):4650-5.

32.

Quantitative assessment of human immunodeficiency virus type 1 replication in human xenografts of acutely infected Hu-PBL-SCID mice.

Koup RA, Hesselton RM, Safrit JT, Somasundaran M, Sullivan JL.

AIDS Res Hum Retroviruses. 1994 Mar;10(3):279-84.

PMID:
8018388
34.
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