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Items: 45

1.

Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene.

Sandlesh P, Juang T, Safina A, Higgins MJ, Gurova KV.

PLoS One. 2018 Jun 28;13(6):e0199785. doi: 10.1371/journal.pone.0199785. eCollection 2018.

2.

TGF-β signaling promotes tumor vasculature by enhancing the pericyte-endothelium association.

Zonneville J, Safina A, Truskinovsky AM, Arteaga CL, Bakin AV.

BMC Cancer. 2018 Jun 19;18(1):670. doi: 10.1186/s12885-018-4587-z.

3.

TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells.

Leonova K, Safina A, Nesher E, Sandlesh P, Pratt R, Burkhart C, Lipchick B, Gitlin I, Frangou C, Koman I, Wang J, Kirsanov K, Yakubovskaya MG, Gudkov AV, Gurova K.

Elife. 2018 Feb 5;7. pii: e30842. doi: 10.7554/eLife.30842.

4.

Role of Chromatin Damage and Chromatin Trapping of FACT in Mediating the Anticancer Cytotoxicity of DNA-Binding Small-Molecule Drugs.

Nesher E, Safina A, Aljahdali I, Portwood S, Wang ES, Koman I, Wang J, Gurova KV.

Cancer Res. 2018 Mar 15;78(6):1431-1443. doi: 10.1158/0008-5472.CAN-17-2690. Epub 2018 Jan 16.

PMID:
29339544
5.

Tumor p38MAPK signaling enhances breast carcinoma vascularization and growth by promoting expression and deposition of pro-tumorigenic factors.

Limoge M, Safina A, Truskinovsky AM, Aljahdali I, Zonneville J, Gruevski A, Arteaga CL, Bakin AV.

Oncotarget. 2017 Jun 28;8(37):61969-61981. doi: 10.18632/oncotarget.18755. eCollection 2017 Sep 22.

6.

Tumor-fibroblast interactions stimulate tumor vascularization by enhancing cytokine-driven production of MMP9 by tumor cells.

Limoge M, Safina A, Beattie A, Kapus L, Truskinovsky AM, Bakin AV.

Oncotarget. 2017 May 30;8(22):35592-35608. doi: 10.18632/oncotarget.16022.

7.

Level of FACT defines the transcriptional landscape and aggressive phenotype of breast cancer cells.

Fleyshman D, Prendergast L, Safina A, Paszkiewicz G, Commane M, Morgan K, Attwood K, Gurova K.

Oncotarget. 2017 Mar 28;8(13):20525-20542. doi: 10.18632/oncotarget.15656.

8.

FACT is a sensor of DNA torsional stress in eukaryotic cells.

Safina A, Cheney P, Pal M, Brodsky L, Ivanov A, Kirsanov K, Lesovaya E, Naberezhnov D, Nesher E, Koman I, Wang D, Wang J, Yakubovskaya M, Winkler D, Gurova K.

Nucleic Acids Res. 2017 Feb 28;45(4):1925-1945. doi: 10.1093/nar/gkw1366.

9.

Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma.

Barone TA, Burkhart CA, Safina A, Haderski G, Gurova KV, Purmal AA, Gudkov AV, Plunkett RJ.

Neuro Oncol. 2017 Feb 1;19(2):186-196. doi: 10.1093/neuonc/now141.

10.

ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin.

Fleyshman D, Cheney P, Ströse A, Mudambi S, Safina A, Commane M, Purmal A, Morgan K, Wang NJ, Gray J, Spellman PT, Issaeva N, Gurova K.

Cell Cycle. 2016;15(3):455-70. doi: 10.1080/15384101.2015.1127478. Epub 2015 Dec 22.

11.

Clinical conferences for physicians: Who sets the agenda?

Abakumova TR, Safina AF, Ziganshina LE.

Int J Risk Saf Med. 2015;27 Suppl 1:S91-2. doi: 10.3233/JRS-150703.

PMID:
26639730
12.

Acute kidney injury in neonatal intensive care: Medicines involved.

Safina AI, Daminova MA, Abdullina GA.

Int J Risk Saf Med. 2015;27 Suppl 1:S9-S10. doi: 10.3233/JRS-150669.

PMID:
26639729
13.

Precision imaging-its impact on image quality and diagnostic confidence in breast ultrasound examinations.

Safina A, Lau L, Brennan P, Mello-Thoms C, Kench P, Ryan E, McEntee M, Rickard M.

Br J Radiol. 2015 Oct;88(1054):20140340. doi: 10.1259/bjr.20140340.

14.

[Palivizumab: four seasons in Russia].

Baranov AA, Ivanov DO, Aliamovskaia GA, Amirova VR, Antoniuk IV, Asmolova GA, Beliaeva IA, Bokeria EL, Briukhanova OA, Vinogradova IV, Vlasova EV, Galustian AN, Gafarova GV, Gorev VV, Davydova IV, Degtiarev DN, Degtiareva EA, Dolgikh VV, Donits IM, Zakharova NI, Zernova LIu, Zimina EP, Zuev VV, Keshishian ES, Kovalev IA, Koltunov IE, Korsunskiĭ AA, Krivoshchekov EV, Krsheminskaia IV, Kuznetsova SN, Liubimenko VA, Namazova-Baranova LS, Nesterenko ÉV, Nikolaev SV, Ovsiannikov DIu, Pavlova TI, Potapova MV, Rychkova LV, Safarov AA, Safina AI, Skachkova MA, Soldatova IG, Turti TV, Filatova NA, Shakirova RM, Ianulevich OS.

Vestn Ross Akad Med Nauk. 2014;(7-8):54-66, 68. Russian.

PMID:
25563005
15.

Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells.

Safina A, Garcia H, Commane M, Guryanova O, Degan S, Kolesnikova K, Gurova KV.

Cell Cycle. 2013 Aug 1;12(15):2423-34. doi: 10.4161/cc.25452. Epub 2013 Jun 28.

16.

Facilitates chromatin transcription complex is an "accelerator" of tumor transformation and potential marker and target of aggressive cancers.

Garcia H, Miecznikowski JC, Safina A, Commane M, Ruusulehto A, Kilpinen S, Leach RW, Attwood K, Li Y, Degan S, Omilian AR, Guryanova O, Papantonopoulou O, Wang J, Buck M, Liu S, Morrison C, Gurova KV.

Cell Rep. 2013 Jul 11;4(1):159-73. doi: 10.1016/j.celrep.2013.06.013. Epub 2013 Jul 3.

17.

Targeting FACT complex suppresses mammary tumorigenesis in Her2/neu transgenic mice.

Koman IE, Commane M, Paszkiewicz G, Hoonjan B, Pal S, Safina A, Toshkov I, Purmal AA, Wang D, Liu S, Morrison C, Gudkov AV, Gurova KV.

Cancer Prev Res (Phila). 2012 Aug;5(8):1025-35. doi: 10.1158/1940-6207.CAPR-11-0529. Epub 2012 Jun 11.

18.

Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells.

Garcia H, Fleyshman D, Kolesnikova K, Safina A, Commane M, Paszkiewicz G, Omelian A, Morrison C, Gurova K.

Oncotarget. 2011 Oct;2(10):783-96.

19.

Curaxins: anticancer compounds that simultaneously suppress NF-κB and activate p53 by targeting FACT.

Gasparian AV, Burkhart CA, Purmal AA, Brodsky L, Pal M, Saranadasa M, Bosykh DA, Commane M, Guryanova OA, Pal S, Safina A, Sviridov S, Koman IE, Veith J, Komar AA, Gudkov AV, Gurova KV.

Sci Transl Med. 2011 Aug 10;3(95):95ra74. doi: 10.1126/scitranslmed.3002530.

20.

TAK1-TAB2 signaling contributes to bone destruction by breast carcinoma cells.

Safina A, Sotomayor P, Limoge M, Morrison C, Bakin AV.

Mol Cancer Res. 2011 Aug;9(8):1042-53. doi: 10.1158/1541-7786.MCR-10-0196. Epub 2011 Jun 23.

21.

Ras alters epithelial-mesenchymal transition in response to TGFbeta by reducing actin fibers and cell-matrix adhesion.

Safina AF, Varga AE, Bianchi A, Zheng Q, Kunnev D, Liang P, Bakin AV.

Cell Cycle. 2009 Jan 15;8(2):284-98.

PMID:
19177011
22.

Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion.

Kulawiec M, Safina A, Desouki MM, Still I, Matsui S, Bakin A, Singh KK.

Cancer Biol Ther. 2008 Nov;7(11):1732-43. Epub 2008 Nov 4.

23.

TAK1 is required for TGF-beta 1-mediated regulation of matrix metalloproteinase-9 and metastasis.

Safina A, Ren MQ, Vandette E, Bakin AV.

Oncogene. 2008 Feb 21;27(9):1198-207. Epub 2007 Sep 10.

PMID:
17828308
24.

Role of high-molecular weight tropomyosins in TGF-beta-mediated control of cell motility.

Zheng Q, Safina A, Bakin AV.

Int J Cancer. 2008 Jan 1;122(1):78-90.

25.

Down-regulation of WAVE3, a metastasis promoter gene, inhibits invasion and metastasis of breast cancer cells.

Sossey-Alaoui K, Safina A, Li X, Vaughan MM, Hicks DG, Bakin AV, Cowell JK.

Am J Pathol. 2007 Jun;170(6):2112-21.

26.

Basal induction of cytochrome P-450 1A1/1A2 in cells of the liver, small intestinal villi, and lymph nodes in rats.

Borodin YI, Maiborodin IV, Safina AF, Strunkin DN.

Bull Exp Biol Med. 2006 Jun;141(6):748-50. English, Russian.

PMID:
17364066
27.

ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells.

Safina A, Vandette E, Bakin AV.

Oncogene. 2007 Apr 12;26(17):2407-22. Epub 2006 Oct 30.

PMID:
17072348
28.

The possibility of cytochrome P450 1A1/1A2 induction in cells of distant lymph nodes of rats after enteral treatment with benzo[a]pyrene.

Borodin YI, Maiborodin IV, Safina AF, Strunkin DN.

Bull Exp Biol Med. 2005 Nov;140(5):564-7.

PMID:
16758626
29.

Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta.

Varga AE, Stourman NV, Zheng Q, Safina AF, Quan L, Li X, Sossey-Alaoui K, Bakin AV.

Oncogene. 2005 Jul 28;24(32):5043-52.

PMID:
15897890
30.

[Influence of the activation of the immune system cells on the parameters of lipid metabolism in macrophages].

Dushkin MI, Perminova OM, Safina AF, Vol'skiĭ NN, Shvarts IaSh, Kozlov VA.

Zh Mikrobiol Epidemiol Immunobiol. 2004 Nov-Dec;(6):52-6. Russian.

PMID:
15636141
31.

Benzo[alpyrene induction of cytochrome P450 1A1/1A2 in the lymph nodes of rats.

Borodin YI, Safina AF, Maiborodin IV, Grishanova AY.

Bull Exp Biol Med. 2003 Dec;136(6):611-4.

PMID:
15500086
32.

A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells.

Bakin AV, Safina A, Rinehart C, Daroqui C, Darbary H, Helfman DM.

Mol Biol Cell. 2004 Oct;15(10):4682-94. Epub 2004 Aug 18.

33.

Bone mineralization in senescence-accelerated OXYS rats.

Kolosova NG, Kutorgin GD, Safina AF.

Bull Exp Biol Med. 2002 Feb;133(2):171-4.

PMID:
12428287
34.

[Effect of stimulation and inhibition of macrophage functions on hypercholesterolemia in rats].

Kuznetsov PO, Safina AF, Shvarts IaSh, Tsyrendorzhiev DD, Zubakhin AA, Dushkin MI.

Vopr Med Khim. 2002 Mar-Apr;48(2):180-8. Russian.

PMID:
12189625
35.

[Effect of 25-hydroxycholesterol and progesterone on esterification of cholesterol, viscosity, and protein-lipid interactions in macrophage membranes].

Dushkin MI, Kolosova NG, Safina AF.

Biull Eksp Biol Med. 2000 Feb;129(2):145-8. Russian. No abstract available.

PMID:
10732231
36.

[Effects of hydroxysterols on expression of inflammatory cytokine genes and their level in macrophages tolerant to endotoxin].

Dushkin MI, Vereshchagin EI, Grebenshchikov AIu, Safina AF, Shvarts IaSh.

Biull Eksp Biol Med. 1999 Jan;127(1):71-4. Russian. No abstract available.

PMID:
10190010
37.
38.

[Endocytosis by liver cells during stimulation of the mononuclear phagocyte system by yeast polysaccharides].

Urazgaliev KSh, Mynkina GI, Pravotorov GV, Demidenko NIa, Safina AF, Kashkina MA, Korolenko TA.

Biull Eksp Biol Med. 1992 Sep;114(9):276-8. Russian.

PMID:
1477357
39.

Endocytosis by liver cells during suppression of intralysosomal proteolysis.

Korolenko TA, Rukavishnikova EV, Safina AF, Dushkin MI, Mynkina GI.

Biol Chem Hoppe Seyler. 1992 Jul;373(7):573-80.

PMID:
1515086
40.

Liver and serum lysosomal enzymes activity during zymosan-induced inflammation in mice.

Safina AF, Korolenko TA, Mynkina GI, Dushkin MI, Krasnoselskaya GA.

Agents Actions Suppl. 1992;38 ( Pt 3):370-5.

PMID:
1462869
41.

Immunomodulators, inflammation and lysosomal proteinases of macrophages.

Safina A, Korolenko T, Mynkina G, Dushkin M, Krasnoselskaya G.

Agents Actions Suppl. 1992;38 ( Pt 2):191-7.

PMID:
1462826
42.

Macrophage stimulation and proteinase/proteinase inhibitors balance during inflammation.

Korolenko TA, Safina AF, Véreschagin EI, Dushkin MI.

Folia Histochem Cytobiol. 1992;30(4):215-7. No abstract available.

PMID:
1303906
43.

Effects of chloroquine on lysosomes and endocytosis by liver cells in vivo.

Korolenko TA, Rukavishnikova EV, Safina AF, Mynkina GI, Vereshchagin EI.

Acta Biol Hung. 1991;42(1-3):301-9.

PMID:
1844318
44.

Look at people--not handicaps.

Safina A.

RN. 1988 Jun;51(6):23-4. No abstract available.

PMID:
2967538
45.

NFormation: NF information on-line.

Safina AX Jr.

Neurofibromatosis. 1988;1(3):188. No abstract available.

PMID:
3152470

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