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Items: 47

1.

Catha Edulis Active Principle, Cathinone, Suppresses Motor Coordination, Accelerates Anxiety and Alters the Levels of Dopamine and its Metabolites in the Limbic Areas of Male Swiss Albino Mice.

Safhi MM, Alam MF, Khuwaja G, Hussain S, Siddiqui MH, Islam F, Khardali I, Al-Sanosi RM, Alhazmi HA, Khan A, Islam F.

Acta Pharm. 2018 Dec 1;68(4):485-495. doi: 10.2478/acph-2018-0038.

PMID:
31259709
2.

Hepatoprotective Potential of Sargassum muticum against STZ-Induced Diabetic Liver Damage in Wistar Rats by Inhibiting Cytokines and the Apoptosis Pathway.

Safhi MM, Alam MF, Sivakumar SM, Anwer T.

Anal Cell Pathol (Amst). 2019 Feb 27;2019:7958701. doi: 10.1155/2019/7958701. eCollection 2019.

3.

The combination of canagliflozin and omega-3 fatty acid ameliorates insulin resistance and cardiac biomarkers via modulation of inflammatory cytokines in type 2 diabetic rats.

Safhi MM, Anwer T, Khan G, Siddiqui R, Moni Sivakumar S, Alam MF.

Korean J Physiol Pharmacol. 2018 Sep;22(5):493-501. doi: 10.4196/kjpp.2018.22.5.493. Epub 2018 Aug 27.

4.

Therapeutic potential of Vanillylacetone against CCl4 induced hepatotoxicity by suppressing the serum marker, oxidative stress, inflammatory cytokines and apoptosis in Swiss albino mice.

Alam MF, Safhi MM, Anwer T, Siddiqui R, Khan G, Moni SS.

Exp Mol Pathol. 2018 Aug;105(1):81-88. doi: 10.1016/j.yexmp.2018.06.001. Epub 2018 Jun 20.

PMID:
29909158
5.

Thymoquinone Ameliorates Doxorubicin-Induced Cardiotoxicity in Swiss Albino Mice by Modulating Oxidative Damage and Cellular Inflammation.

Alam MF, Khan G, Safhi MM, Alshahrani S, Siddiqui R, Sivagurunathan Moni S, Anwer T.

Cardiol Res Pract. 2018 Apr 1;2018:1483041. doi: 10.1155/2018/1483041. eCollection 2018.

6.

Nephroprotective Effect of Zingerone against CCl4-Induced Renal Toxicity in Swiss Albino Mice: Molecular Mechanism.

Safhi MM.

Oxid Med Cell Longev. 2018 Jan 30;2018:2474831. doi: 10.1155/2018/2474831. eCollection 2018.

7.

Thymoquinone and fluoxetine alleviate depression via attenuating oxidative damage and inflammatory markers in type-2 diabetic rats.

Safhi MM, Qumayri HM, Masmali AUM, Siddiqui R, Alam MF, Khan G, Anwer T.

Arch Physiol Biochem. 2019 May;125(2):150-155. doi: 10.1080/13813455.2018.1443141. Epub 2018 Feb 26.

PMID:
29482373
8.

REPEATED EXPOSURE OF SODIUM TELLURITE ON THE RAT LIVER AND ON THE POTENTIAL MECHANISMS OF THE METALLOID-INDUCED HEPATOTOXICITY.

Safhi MM, Alam MF, Khuwaja G, Islam F, Hussain S, Fageeh MM, Anwer T, Islam F.

Acta Pol Pharm. 2017 Jan;74(1):103-109.

PMID:
29474766
9.

REPEATED EXPOSURE OF SODIUM TELLURITE ON THE RAT LIVER AND ON THE POTENTIAL MECHANISMS OF THE METALLOID-INDUCED HEPATOTOXICITY.

Safhi MM, Alam MF, Khuwaja G, Islam F, Hussain S, Fageeh MM, Anwer T, Islam F.

Acta Pol Pharm. 2016 May-Jun;73(3):675-82.

PMID:
27476286
10.
11.

In Vitro Antibacterial Spectrum of Sodium Selenite against Selected Human Pathogenic Bacterial Strains.

Alam MF, Safhi MM, Moni SS, Jabeen A.

Scientifica (Cairo). 2016;2016:9176273. doi: 10.1155/2016/9176273. Epub 2016 Mar 15.

12.

Effect of hesperidin on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in intracerebroventricular streptozotocin induced cognitive impairment in mice.

Javed H, Vaibhav K, Ahmed ME, Khan A, Tabassum R, Islam F, Safhi MM, Islam F.

J Neurol Sci. 2015 Jan 15;348(1-2):51-9. doi: 10.1016/j.jns.2014.10.044. Epub 2014 Nov 6.

PMID:
25434716
13.

Cardioprotective effect of green tea extract on doxorubicin-induced cardiotoxicity in rats.

Khan G, Haque SE, Anwer T, Ahsan MN, Safhi MM, Alam MF.

Acta Pol Pharm. 2014 Sep-Oct;71(5):861-8.

14.

Perillyl alcohol improves functional and histological outcomes against ischemia-reperfusion injury by attenuation of oxidative stress and repression of COX-2, NOS-2 and NF-κB in middle cerebral artery occlusion rats.

Tabassum R, Vaibhav K, Shrivastava P, Khan A, Ahmed ME, Ashafaq M, Khan MB, Islam F, Safhi MM, Islam F.

Eur J Pharmacol. 2015 Jan 15;747:190-9. doi: 10.1016/j.ejphar.2014.09.015. Epub 2014 Sep 18.

PMID:
25240714
15.

Cathinone, an active principle of Catha edulis, accelerates oxidative stress in the limbic area of swiss albino mice.

Safhi MM, Alam MF, Hussain S, Hakeem Siddiqui MA, Khuwaja G, Jubran Khardali IA, Al-Sanosi RM, Islam F.

J Ethnopharmacol. 2014 Oct 28;156:102-6. doi: 10.1016/j.jep.2014.08.004. Epub 2014 Aug 19.

PMID:
25153022
16.

Nanoparticles for triggering and regulation of immune response of vaccines: perspective and prospective.

Moni SS, Safhi MM, Barik BB.

Curr Pharm Biotechnol. 2013;14(15):1242-9. Review.

PMID:
25106651
17.

Accelerated Stability Testing of a Clobetasol Propionate-Loaded Nanoemulsion as per ICH Guidelines.

Ali MS, Alam MS, Alam N, Anwer T, Safhi MM.

Sci Pharm. 2013 Apr 7;81(4):1089-100. doi: 10.3797/scipharm.1210-02. Print 2013 Oct-Dec.

18.

1,8-cineole (eucalyptol) mitigates inflammation in amyloid Beta toxicated PC12 cells: relevance to Alzheimer's disease.

Khan A, Vaibhav K, Javed H, Tabassum R, Ahmed ME, Khan MM, Khan MB, Shrivastava P, Islam F, Siddiqui MS, Safhi MM, Islam F.

Neurochem Res. 2014 Feb;39(2):344-52. doi: 10.1007/s11064-013-1231-9. Epub 2013 Dec 31.

PMID:
24379109
19.

Pluchea lanceolata protects against Benzo(a) pyrene induced renal toxicity and loss of DNA integrity.

Jahangir T, Safhi MM, Sultana S, Ahmad S.

Interdiscip Toxicol. 2013 Mar;6(1):47-54. doi: 10.2478/intox-2013-0009.

20.

Rhus coriaria ameliorates insulin resistance in non-insulin-dependent diabetes mellitus (NIDDM) rats.

Anwer T, Sharma M, Khan G, Iqbal M, Ali MS, Alam MS, Safhi MM, Gupta N.

Acta Pol Pharm. 2013 Sep-Oct;70(5):861-7.

21.

Delayed administration of zingerone mitigates the behavioral and histological alteration via repression of oxidative stress and intrinsic programmed cell death in focal transient ischemic rats.

Vaibhav K, Shrivastava P, Tabassum R, Khan A, Javed H, Ahmed ME, Islam F, Safhi MM, Islam F.

Pharmacol Biochem Behav. 2013 Nov 15;113:53-62. doi: 10.1016/j.pbb.2013.10.008. Epub 2013 Oct 18.

PMID:
24141173
22.

Isolation and screening of bioactive principle from Chaetomorpha antennina against certain bacterial strains.

Sivakumar SM, Safhi MM.

Saudi Pharm J. 2013 Jan;21(1):119-21. doi: 10.1016/j.jsps.2012.02.003. Epub 2012 Feb 23.

23.

Taurine ameliorates neurobehavioral, neurochemical and immunohistochemical changes in sporadic dementia of Alzheimer's type (SDAT) caused by intracerebroventricular streptozotocin in rats.

Javed H, Khan A, Vaibhav K, Moshahid Khan M, Ahmad A, Ejaz Ahmad M, Ahmad A, Tabassum R, Islam F, Safhi MM, Islam F.

Neurol Sci. 2013 Dec;34(12):2181-92. doi: 10.1007/s10072-013-1444-3. Epub 2013 May 17.

PMID:
23681104
24.

Amelioration of cognitive impairment and neurodegeneration by catechin hydrate in rat model of streptozotocin-induced experimental dementia of Alzheimer's type.

Ejaz Ahmed M, Khan MM, Javed H, Vaibhav K, Khan A, Tabassum R, Ashafaq M, Islam F, Safhi MM, Islam F.

Neurochem Int. 2013 Mar;62(4):492-501. doi: 10.1016/j.neuint.2013.02.006. Epub 2013 Feb 11.

PMID:
23411413
25.

Attenuation of oxidative damage-associated cognitive decline by Withania somnifera in rat model of streptozotocin-induced cognitive impairment.

Ahmed ME, Javed H, Khan MM, Vaibhav K, Ahmad A, Khan A, Tabassum R, Islam F, Safhi MM, Islam F.

Protoplasma. 2013 Oct;250(5):1067-78. doi: 10.1007/s00709-013-0482-2. Epub 2013 Jan 23.

PMID:
23340606
26.

Azadirachta indica mitigates behavioral impairments, oxidative damage, histological alterations and apoptosis in focal cerebral ischemia-reperfusion model of rats.

Vaibhav K, Shrivastava P, Khan A, Javed H, Tabassum R, Ahmed ME, Khan MB, Moshahid Khan M, Islam F, Ahmad S, Siddiqui MS, Safhi MM, Islam F.

Neurol Sci. 2013 Aug;34(8):1321-30. doi: 10.1007/s10072-012-1238-z. Epub 2012 Nov 28.

PMID:
23187787
27.

Neuroprotective effect of naringenin is mediated through suppression of NF-κB signaling pathway in experimental stroke.

Raza SS, Khan MM, Ahmad A, Ashafaq M, Islam F, Wagner AP, Safhi MM, Islam F.

Neuroscience. 2013 Jan 29;230:157-71. doi: 10.1016/j.neuroscience.2012.10.041. Epub 2012 Oct 26.

PMID:
23103795
28.

Centella asiatica attenuates the neurobehavioral, neurochemical and histological changes in transient focal middle cerebral artery occlusion rats.

Tabassum R, Vaibhav K, Shrivastava P, Khan A, Ejaz Ahmed M, Javed H, Islam F, Ahmad S, Saeed Siddiqui M, Safhi MM, Islam F.

Neurol Sci. 2013 Jun;34(6):925-33. doi: 10.1007/s10072-012-1163-1. Epub 2012 Aug 4.

PMID:
22864972
29.

Anti-apoptotic and anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's rat model.

Shrivastava P, Vaibhav K, Tabassum R, Khan A, Ishrat T, Khan MM, Ahmad A, Islam F, Safhi MM, Islam F.

J Nutr Biochem. 2013 Apr;24(4):680-7. doi: 10.1016/j.jnutbio.2012.03.018. Epub 2012 Jul 20.

PMID:
22819561
30.

Attenuation of Aβ-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress.

Khan A, Vaibhav K, Javed H, Khan MM, Tabassum R, Ahmed ME, Srivastava P, Khuwaja G, Islam F, Siddiqui MS, Safhi MM, Islam F.

Mol Cell Biochem. 2012 Oct;369(1-2):55-65. doi: 10.1007/s11010-012-1368-x. Epub 2012 Jul 1. Erratum in: Mol Cell Biochem. 2013 Apr;376(1-2):197. Shafi, Mohammed M [corrected to Safhi, Mohammed M].

PMID:
22752387
31.

Piperine suppresses cerebral ischemia-reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat model.

Vaibhav K, Shrivastava P, Javed H, Khan A, Ahmed ME, Tabassum R, Khan MM, Khuwaja G, Islam F, Siddiqui MS, Safhi MM, Islam F.

Mol Cell Biochem. 2012 Aug;367(1-2):73-84. doi: 10.1007/s11010-012-1321-z. Epub 2012 Jun 6.

PMID:
22669728
32.

Edaravone ameliorates oxidative stress associated cholinergic dysfunction and limits apoptotic response following focal cerebral ischemia in rat.

Ahmad A, Khan MM, Javed H, Raza SS, Ishrat T, Khan MB, Safhi MM, Islam F.

Mol Cell Biochem. 2012 Aug;367(1-2):215-25. doi: 10.1007/s11010-012-1335-6. Epub 2012 May 22.

PMID:
22648734
33.

Catechin hydrate ameliorates redox imbalance and limits inflammatory response in focal cerebral ischemia.

Ashafaq M, Raza SS, Khan MM, Ahmad A, Javed H, Ahmad ME, Tabassum R, Islam F, Siddiqui MS, Safhi MM, Islam F.

Neurochem Res. 2012 Aug;37(8):1747-60. doi: 10.1007/s11064-012-0786-1. Epub 2012 May 9.

PMID:
22570178
34.

Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type.

Javed H, Khan MM, Ahmad A, Vaibhav K, Ahmad ME, Khan A, Ashafaq M, Islam F, Siddiqui MS, Safhi MM, Islam F.

Neuroscience. 2012 May 17;210:340-52. doi: 10.1016/j.neuroscience.2012.02.046. Epub 2012 Mar 6.

PMID:
22441036
35.

An insight into the new anticonvulsant agents.

Ahsan W, Safhi MM, Siddiqui N, Javed S, Alam MS, Azad B, Akhtar J.

Curr Top Med Chem. 2012;12(9):1072-92. Review.

PMID:
22352863
36.

S-allyl cysteine mitigates oxidative damage and improves neurologic deficit in a rat model of focal cerebral ischemia.

Ashafaq M, Khan MM, Shadab Raza S, Ahmad A, Khuwaja G, Javed H, Khan A, Islam F, Siddiqui MS, Safhi MM, Islam F.

Nutr Res. 2012 Feb;32(2):133-43. doi: 10.1016/j.nutres.2011.12.014.

PMID:
22348462
37.

Ocimum sanctum attenuates oxidative damage and neurological deficits following focal cerebral ischemia/reperfusion injury in rats.

Ahmad A, Khan MM, Raza SS, Javed H, Ashafaq M, Islam F, Safhi MM, Islam F.

Neurol Sci. 2012 Dec;33(6):1239-47. doi: 10.1007/s10072-012-0940-1. Epub 2012 Jan 26.

PMID:
22278208
38.

Rutin protects dopaminergic neurons from oxidative stress in an animal model of Parkinson's disease.

Khan MM, Raza SS, Javed H, Ahmad A, Khan A, Islam F, Safhi MM, Islam F.

Neurotox Res. 2012 Jul;22(1):1-15. doi: 10.1007/s12640-011-9295-2. Epub 2011 Dec 23.

PMID:
22194158
39.
40.

Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke.

Raza SS, Khan MM, Ahmad A, Ashafaq M, Khuwaja G, Tabassum R, Javed H, Siddiqui MS, Safhi MM, Islam F.

Brain Res. 2011 Oct 28;1420:93-105. doi: 10.1016/j.brainres.2011.08.047. Epub 2011 Aug 27.

PMID:
21959178
41.

Vaccine adjuvants - Current status and prospects on controlled release adjuvancity.

Sivakumar SM, Safhi MM, Kannadasan M, Sukumaran N.

Saudi Pharm J. 2011 Oct;19(4):197-206. doi: 10.1016/j.jsps.2011.06.003. Epub 2011 Jun 25.

42.

Silymarin protects neurons from oxidative stress associated damages in focal cerebral ischemia: a behavioral, biochemical and immunohistological study in Wistar rats.

Raza SS, Khan MM, Ashafaq M, Ahmad A, Khuwaja G, Khan A, Siddiqui MS, Safhi MM, Islam F.

J Neurol Sci. 2011 Oct 15;309(1-2):45-54. doi: 10.1016/j.jns.2011.07.035. Epub 2011 Aug 15.

PMID:
21840019
43.

Quercetin protects against oxidative stress associated damages in a rat model of transient focal cerebral ischemia and reperfusion.

Ahmad A, Khan MM, Hoda MN, Raza SS, Khan MB, Javed H, Ishrat T, Ashafaq M, Ahmad ME, Safhi MM, Islam F.

Neurochem Res. 2011 Aug;36(8):1360-71. doi: 10.1007/s11064-011-0458-6. Epub 2011 Apr 7.

PMID:
21472457
44.

S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type.

Javed H, Khan MM, Khan A, Vaibhav K, Ahmad A, Khuwaja G, Ahmed ME, Raza SS, Ashafaq M, Tabassum R, Siddiqui MS, El-Agnaf OM, Safhi MM, Islam F.

Brain Res. 2011 May 10;1389:133-42. doi: 10.1016/j.brainres.2011.02.072. Epub 2011 Mar 1.

PMID:
21376020
45.

Neuroprotective effects of curcumin on 6-hydroxydopamine-induced Parkinsonism in rats: behavioral, neurochemical and immunohistochemical studies.

Khuwaja G, Khan MM, Ishrat T, Ahmad A, Raza SS, Ashafaq M, Javed H, Khan MB, Khan A, Vaibhav K, Safhi MM, Islam F.

Brain Res. 2011 Jan 12;1368:254-63. doi: 10.1016/j.brainres.2010.10.023. Epub 2010 Oct 15.

PMID:
20951685
46.

Amelioration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced behavioural dysfunction and oxidative stress by Pycnogenol in mouse model of Parkinson's disease.

Khan MM, Hoda MN, Ishrat T, Ahmad A, Khan MB, Khuwaja G, Raza SS, Safhi MM, Islam F.

Behav Pharmacol. 2010 Sep;21(5-6):563-71. doi: 10.1097/FBP.0b013e32833d4186.

PMID:
20657266
47.

Priming of signal transducer and activator of transcription proteins for cytokine-triggered polyubiquitylation and degradation by the A 2A adenosine receptor.

Safhi MM, Rutherford C, Ledent C, Sands WA, Palmer TM.

Mol Pharmacol. 2010 Jun;77(6):968-78. doi: 10.1124/mol.109.062455. Epub 2010 Feb 25.

PMID:
20185553

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