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Items: 7

1.

Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition.

Scott MT, Korfi K, Saffrey P, Hopcroft LE, Kinstrie R, Pellicano F, Guenther C, Gallipoli P, Cruz M, Dunn K, Jorgensen HG, Cassels JE, Hamilton A, Crossan A, Sinclair A, Holyoake TL, Vetrie D.

Cancer Discov. 2016 Nov;6(11):1248-1257. Epub 2016 Sep 14.

2.

Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL.

Zhou Y, Kurukuti S, Saffrey P, Vukovic M, Michie AM, Strogantsev R, West AG, Vetrie D.

Blood. 2013 Dec 19;122(26):4199-209. doi: 10.1182/blood-2013-02-483875. Epub 2013 Nov 7.

3.

Rapid whole-genome sequencing for genetic disease diagnosis in neonatal intensive care units.

Saunders CJ, Miller NA, Soden SE, Dinwiddie DL, Noll A, Alnadi NA, Andraws N, Patterson ML, Krivohlavek LA, Fellis J, Humphray S, Saffrey P, Kingsbury Z, Weir JC, Betley J, Grocock RJ, Margulies EH, Farrow EG, Artman M, Safina NP, Petrikin JE, Hall KP, Kingsmore SF.

Sci Transl Med. 2012 Oct 3;4(154):154ra135. doi: 10.1126/scitranslmed.3004041.

4.

A composite computational model of liver glucose homeostasis. II. Exploring system behaviour.

Sumner T, Hetherington J, Seymour RM, Li L, Varela Rey M, Yamaji S, Saffrey P, Margoninski O, Bogle ID, Finkelstein A, Warner A.

J R Soc Interface. 2012 Apr 7;9(69):701-6. doi: 10.1098/rsif.2011.0783. Epub 2012 Feb 8.

5.

A composite computational model of liver glucose homeostasis. I. Building the composite model.

Hetherington J, Sumner T, Seymour RM, Li L, Rey MV, Yamaji S, Saffrey P, Margoninski O, Bogle ID, Finkelstein A, Warner A.

J R Soc Interface. 2012 Apr 7;9(69):689-700. doi: 10.1098/rsif.2011.0141. Epub 2011 Jun 15.

6.

Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution.

Dhami P, Saffrey P, Bruce AW, Dillon SC, Chiang K, Bonhoure N, Koch CM, Bye J, James K, Foad NS, Ellis P, Watkins NA, Ouwehand WH, Langford C, Andrews RM, Dunham I, Vetrie D.

PLoS One. 2010 Aug 23;5(8):e12339. doi: 10.1371/journal.pone.0012339.

7.

Version control of pathway models using XML patches.

Saffrey P, Orton R.

BMC Syst Biol. 2009 Mar 17;3:34. doi: 10.1186/1752-0509-3-34.

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