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Items: 49

1.

Contemporary epidemiology of systemic sclerosis: A population-based cohort study in the United Kingdom.

García Rodríguez LA, González-Pérez A, Michel A, Sáez ME.

Semin Arthritis Rheum. 2018 Nov 10. pii: S0049-0172(18)30510-9. doi: 10.1016/j.semarthrit.2018.11.002. [Epub ahead of print]

PMID:
30470546
2.

Hormonal contraception is not associated with increased risk for seizures in the general population: results from a cohort study using The Health Improvement Network.

Beier CP, García Rodríguez LA, Sáez ME, Gaist D, González-Pérez A.

Eur J Clin Pharmacol. 2018 Sep;74(9):1175-1180. doi: 10.1007/s00228-018-2494-5. Epub 2018 May 31.

PMID:
29855657
3.

Low-Dose Aspirin after an Episode of Haemorrhagic Stroke Is Associated with Improved Survival.

González-Pérez A, Gaist D, de Abajo FJ, Sáez ME, García Rodríguez LA.

Thromb Haemost. 2017 Dec;117(12):2396-2405. doi: 10.1160/TH17-05-0342. Epub 2017 Dec 6.

PMID:
29212127
4.

Mortality in patients who discontinue low-dose acetylsalicylic acid therapy after upper gastrointestinal bleeding.

González-Pérez A, Sáez ME, Johansson S, Nagy P, García Rodríguez LA.

Pharmacoepidemiol Drug Saf. 2017 Feb;26(2):215-222. doi: 10.1002/pds.4140. Epub 2016 Dec 6.

PMID:
27921360
5.

Risk of bleeding after hospitalization for a serious coronary event: a retrospective cohort study with nested case-control analyses.

González-Pérez A, Sáez ME, Johansson S, Himmelmann A, García Rodríguez LA.

BMC Cardiovasc Disord. 2016 Aug 30;16(1):164. doi: 10.1186/s12872-016-0348-6.

6.

Risk of seizure associated with use of acid-suppressive drugs: An observational cohort study.

Sáez ME, González-Pérez A, Gaist D, Johansson S, Nagy P, García Rodríguez LA.

Epilepsy Behav. 2016 Sep;62:72-80. doi: 10.1016/j.yebeh.2016.06.039. Epub 2016 Jul 21.

PMID:
27450309
7.

Association between low-dose acetylsalicylic acid reinitiation and the risk of myocardial infarction or coronary heart disease death.

Sáez ME, González-Pérez A, Johansson S, Himmelmann A, García Rodríguez LA.

Eur J Prev Cardiol. 2016 Jul;23(10):1029-36. doi: 10.1177/2047487315618795. Epub 2015 Nov 24.

PMID:
26603743
8.

[Impact of a multidimensional intervention in elderly patients with community-acquired pneumonia: IMIEPCAP clinical trial].

Torres OH, Gil E, Comas MT, Saez ME, Clotet S, Ramirez HD, Mateo M, Ruiz D.

Rev Esp Geriatr Gerontol. 2016 Jan-Feb;51(1):37-43. doi: 10.1016/j.regg.2015.09.004. Epub 2015 Oct 30. Spanish.

PMID:
26526565
9.

Incidence and Predictors of Hemorrhagic Stroke in Users of Low-Dose Acetylsalicylic Acid.

González-Pérez A, Sáez ME, Johansson S, Himmelmann A, García Rodríguez LA.

J Stroke Cerebrovasc Dis. 2015 Oct;24(10):2321-8. doi: 10.1016/j.jstrokecerebrovasdis.2015.06.016. Epub 2015 Jul 15.

PMID:
26189158
10.

Patterns of Antiplatelet Therapy in Patients Who Have Experienced an Acute Coronary Event: A Descriptive Study in UK Primary Care.

Sáez ME, González-Pérez A, Johansson S, Nagy P, Rodríguez LA.

J Cardiovasc Pharmacol Ther. 2015 Jul;20(4):378-86. doi: 10.1177/1074248414562910. Epub 2014 Dec 11.

PMID:
25501499
11.

A new risk variant for multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and oligoclonal bands.

Delgado-García M, Matesanz F, Alcina A, Fedetz M, García-Sánchez MI, Ruiz-Peña JL, Fernández Ó, Pinto Medel MJ, Leyva L, Arnal C, Delgado C, López Guerrero JA, González-Pérez A, Sáez ME, Villar LM, Álvarez-Cermeño JC, Picón C, Arroyo R, Varadé J, Urcelay E, Izquierdo G, Lucas M.

Mult Scler. 2015 Aug;21(9):1104-11. doi: 10.1177/1352458514556302. Epub 2014 Nov 12.

PMID:
25392328
12.

Patterns in the use of low-dose acetylsalicylic acid and other therapies following upper gastrointestinal bleeding.

Sáez ME, González-Pérez A, Johansson S, Nagy P, García Rodríguez LA.

Am J Cardiovasc Drugs. 2014 Dec;14(6):443-50. doi: 10.1007/s40256-014-0088-x.

PMID:
25119521
13.

Risk factors associated with uncomplicated peptic ulcer and changes in medication use after diagnosis.

González-Pérez A, Sáez ME, Johansson S, Nagy P, García Rodríguez LA.

PLoS One. 2014 Jul 8;9(7):e101768. doi: 10.1371/journal.pone.0101768. eCollection 2014.

14.

A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis.

Real LM, Ruiz A, Gayán J, González-Pérez A, Sáez ME, Ramírez-Lorca R, Morón FJ, Velasco J, Marginet-Flinch R, Musulén E, Carrasco JM, Moreno-Rey C, Vázquez E, Chaves-Conde M, Moreno-Nogueira JA, Hidalgo-Pascual M, Ferrero-Herrero E, Castellví-Bel S, Castells A, Fernandez-Rozadilla C, Ruiz-Ponte C, Carracedo A, González B, Alonso S, Perucho M.

PLoS One. 2014 Jun 30;9(6):e101178. doi: 10.1371/journal.pone.0101178. eCollection 2014.

15.

ATP5H/KCTD2 locus is associated with Alzheimer's disease risk.

Boada M, Antúnez C, Ramírez-Lorca R, DeStefano AL, González-Pérez A, Gayán J, López-Arrieta J, Ikram MA, Hernández I, Marín J, Galán JJ, Bis JC, Mauleón A, Rosende-Roca M, Moreno-Rey C, Gudnasson V, Morón FJ, Velasco J, Carrasco JM, Alegret M, Espinosa A, Vinyes G, Lafuente A, Vargas L, Fitzpatrick AL; Alzheimer’s Disease Neuroimaging Initiative, Launer LJ, Sáez ME, Vázquez E, Becker JT, López OL, Serrano-Ríos M, Tárraga L, van Duijn CM, Real LM, Seshadri S, Ruiz A.

Mol Psychiatry. 2014 Jun;19(6):682-7. doi: 10.1038/mp.2013.86. Epub 2013 Jul 16.

16.

Genetic analysis of candidate SNPs for metabolic syndrome in obstructive sleep apnea (OSA).

Grilo A, Ruiz-Granados ES, Moreno-Rey C, Rivera JM, Ruiz A, Real LM, Sáez ME.

Gene. 2013 May 25;521(1):150-4. doi: 10.1016/j.gene.2013.03.024. Epub 2013 Mar 21.

17.

Genetic study of neurexin and neuroligin genes in Alzheimer's disease.

Martinez-Mir A, González-Pérez A, Gayán J, Antúnez C, Marín J, Boada M, Lopez-Arrieta JM, Fernández E, Ramírez-Lorca R, Sáez ME, Ruiz A, Scholl FG, Real LM.

J Alzheimers Dis. 2013;35(2):403-12. doi: 10.3233/JAD-122257.

PMID:
23403532
18.

The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.

Antúnez C, Boada M, González-Pérez A, Gayán J, Ramírez-Lorca R, Marín J, Hernández I, Moreno-Rey C, Morón FJ, López-Arrieta J, Mauleón A, Rosende-Roca M, Noguera-Perea F, Legaz-García A, Vivancos-Moreau L, Velasco J, Carrasco JM, Alegret M, Antequera-Torres M, Manzanares S, Romo A, Blanca I, Ruiz S, Espinosa A, Castaño S, García B, Martínez-Herrada B, Vinyes G, Lafuente A, Becker JT, Galán JJ, Serrano-Ríos M; Alzheimer's Disease Neuroimaging Initiative, Vázquez E, Tárraga L, Sáez ME, López OL, Real LM, Ruiz A.

Genome Med. 2011 May 31;3(5):33. doi: 10.1186/gm249.

19.

Association analysis of urotensin II gene (UTS2) and flanking regions with biochemical parameters related to insulin resistance.

Sáez ME, Smani T, Ramírez-Lorca R, Díaz I, Serrano-Ríos M, Ruiz A, Ordoñez A.

PLoS One. 2011 Apr 29;6(4):e19327. doi: 10.1371/journal.pone.0019327.

20.

Evidence for a link between TNFRSF11A and risk of breast cancer.

Bonifaci N, Palafox M, Pellegrini P, Osorio A, Benítez J, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Roversi G, Barile M, Viel A, Mariette F, Bernard L, Radice P, Kaufman B, Laitman Y, Milgrom R, Friedman E, Sáez ME, Climent F, Soler MT, Diez O, Balmaña J, Lasa A, Ramón y Cajal T, Miramar MD, de la Hoya M, Pérez-Segura P, Caldés T, Moreno V, Urruticoechea A, Brunet J, Lázaro C, Blanco I, Pujana MA, González-Suárez E.

Breast Cancer Res Treat. 2011 Oct;129(3):947-54. doi: 10.1007/s10549-011-1546-7. Epub 2011 May 4.

PMID:
21541702
21.

Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.

Grilo A, Sáez-Rosas MP, Santos-Morano J, Sánchez E, Moreno-Rey C, Real LM, Ramírez-Lorca R, Sáez ME.

Pharmacogenet Genomics. 2011 Jan;21(1):10-7. doi: 10.1097/FPC.0b013e328341041c.

PMID:
21052031
22.

WWOX gene is associated with HDL cholesterol and triglyceride levels.

Sáez ME, González-Pérez A, Martínez-Larrad MT, Gayán J, Real LM, Serrano-Ríos M, Ruiz A.

BMC Med Genet. 2010 Oct 14;11:148. doi: 10.1186/1471-2350-11-148.

23.

Calpain 10 gene and laryngeal cancer: a survival analysis.

Moreno-Luna R, Abrante A, Esteban F, González-Moles MA, Delgado-Rodríguez M, Sáez ME, González-Pérez A, Ramírez-Lorca R, Real LM, Ruiz A.

Head Neck. 2011 Jan;33(1):72-6. doi: 10.1002/hed.21404.

PMID:
20848425
24.

Estrogen receptor alpha gene variants are associated with Alzheimer's disease.

Boada M, Antunez C, López-Arrieta J, Caruz A, Moreno-Rey C, Ramírez-Lorca R, Morón FJ, Hernández I, Mauleón A, Rosende-Roca M, Martínez-Lage P, Marín J, Tárraga L, Alegret M, Pedrajas JR, Urda N, Royo JL, Saez ME, Gayán J, González-Pérez A, Real LM, Ruiz A, Galán JJ.

Neurobiol Aging. 2012 Jan;33(1):198.e15-24. doi: 10.1016/j.neurobiolaging.2010.06.016. Epub 2010 Jul 31.

PMID:
20674091
25.

Genetic structure of the Spanish population.

Gayán J, Galan JJ, González-Pérez A, Sáez ME, Martínez-Larrad MT, Zabena C, Rivero MC, Salinas A, Ramírez-Lorca R, Morón FJ, Royo JL, Moreno-Rey C, Velasco J, Carrasco JM, Molero E, Ochoa C, Ochoa MD, Gutiérrez M, Reina M, Pascual R, Romo-Astorga A, Susillo-González JL, Vázquez E, Real LM, Ruiz A, Serrano-Ríos M.

BMC Genomics. 2010 May 25;11:326. doi: 10.1186/1471-2164-11-326.

26.

The TLR4 ASP299GLY polymorphism is a risk factor for active tuberculosis in Caucasian HIV-infected patients.

Pulido I, Leal M, Genebat M, Pacheco YM, Sáez ME, Soriano-Sarabia N.

Curr HIV Res. 2010 Apr;8(3):253-8.

PMID:
20226000
27.

GAB2 gene does not modify the risk of Alzheimer's disease in Spanish APOE 4 carriers.

Ramirez-Lorca R, Boada M, Saez ME, Hernandez I, Mauleon A, Rosende-Roca M, Martinez-Lage P, Gutierrez M, Real LM, Lopez-Arrieta J, Gayan J, Antunez C, Gonzalez-Perez A, Tarraga L, Ruiz A.

J Nutr Health Aging. 2009 Mar;13(3):214-9.

PMID:
19262956
28.

Whole-genome conditional two-locus analysis identifies novel candidate genes for late-onset Parkinson's disease.

González-Pérez A, Gayán J, Marín J, Galán JJ, Sáez ME, Real LM, Antúnez C, Ruiz A.

Neurogenetics. 2009 Jul;10(3):173-81. doi: 10.1007/s10048-009-0170-8. Epub 2009 Jan 21.

PMID:
19156451
29.

Absence of allelic imbalance involving EMSY, CAPN5, and PAK1 genes in papillary thyroid carcinoma.

Hidalgo M, Saez ME, Martinez-Tello FJ, Moron FJ, Ferrero-Herrero E, Labalde-Martinez M, Rigopoulou D, Ballestin-Carcavilla C, Ruiz A, Royo JL, Ramirez-Lorca R.

J Endocrinol Invest. 2008 Jul;31(7):618-23.

PMID:
18787380
30.

Influence of the Toll-like receptor 9 1635A/G polymorphism on the CD4 count, HIV viral load, and clinical progression.

Soriano-Sarabia N, Vallejo A, Ramírez-Lorca R, Rodríguez Mdel M, Salinas A, Pulido I, Sáez ME, Leal M.

J Acquir Immune Defic Syndr. 2008 Oct 1;49(2):128-35. doi: 10.1097/QAI.0b013e318184fb41.

PMID:
18769358
31.

The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population.

Sáez ME, González-Sánchez JL, Ramírez-Lorca R, Martínez-Larrad MT, Zabena C, González A, Morón FJ, Ruiz A, Serrano-Ríos M.

PLoS One. 2008 Aug 13;3(8):e2953. doi: 10.1371/journal.pone.0002953.

32.

A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis.

Gayán J, González-Pérez A, Bermudo F, Sáez ME, Royo JL, Quintas A, Galan JJ, Morón FJ, Ramirez-Lorca R, Real LM, Ruiz A.

BMC Genomics. 2008 Jul 31;9:360. doi: 10.1186/1471-2164-9-360.

33.

Interaction between Calpain 5, Peroxisome proliferator-activated receptor-gamma and Peroxisome proliferator-activated receptor-delta genes: a polygenic approach to obesity.

Sáez ME, Grilo A, Morón FJ, Manzano L, Martínez-Larrad MT, González-Pérez A, Serrano-Hernando J, Ruiz A, Ramírez-Lorca R, Serrano-Ríos M.

Cardiovasc Diabetol. 2008 Jul 25;7:23. doi: 10.1186/1475-2840-7-23.

34.

Association of genetic markers within the BMP15 gene with anovulation and infertility in women with polycystic ovary syndrome.

Gónzalez A, Ramírez-Lorca R, Calatayud C, Mendoza N, Ruiz A, Sáez ME, Morón FJ.

Fertil Steril. 2008 Aug;90(2):447-9. Epub 2007 Oct 1.

PMID:
17905236
35.

Sex and body mass index specific regulation of blood pressure by CYP19A1 gene variants.

Ramirez-Lorca R, Grilo A, Martinez-Larrad MT, Manzano L, Serrano-Hernando FJ, Moron FJ, Perez-Gonzalez V, Gonzalez-Sanchez JL, Fresneda J, Fernandez-Parrilla R, Moñux G, Molero E, Sanchez E, Martinez-Calatrava MJ, Saban-Ruiz J, Ruiz A, Saez ME, Serrano-Rios M.

Hypertension. 2007 Nov;50(5):884-90. Epub 2007 Sep 24.

PMID:
17893373
36.

Identification of a protective haplogenotype within CAPN10 gene influencing colorectal cancer susceptibility.

Frances CP, Conde MC, Saez ME, Diez SF, Rey CM, Ramírez-Armengol JA, Pascual MH, Gonzalez-Perez A, Torres PP, Real LM, Serrano-Rios M, López JL, Ruiz A, Royo JL.

J Gastroenterol Hepatol. 2007 Dec;22(12):2298-302. Epub 2007 Jun 7.

PMID:
17559371
37.

Pyrosequencing technology for automated detection of the BMP15 A180T variant in Spanish postmenopausal women.

Morón FJ, Mendoza N, Quereda F, Vázquez F, Ramírez-Lorca R, Velasco J, Gallo JL, Salinas A, Martínez-Astorquiza T, Sánchez-Borrego R, Sáez ME, Ruiz A.

Clin Chem. 2007 Jun;53(6):1162-4. No abstract available.

38.

Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels.

Sáez ME, Martínez-Larrad MT, Ramírez-Lorca R, González-Sánchez JL, Zabena C, Martinez-Calatrava MJ, González A, Morón FJ, Ruiz A, Serrano-Ríos M.

BMC Med Genet. 2007 Jan 16;8:1.

39.

Endothelial nitric oxide synthase haplotypes are associated with features of metabolic syndrome.

González-Sánchez JL, Martínez-Larrad MT, Sáez ME, Zabena C, Martínez-Calatrava MJ, Serrano-Ríos M.

Clin Chem. 2007 Jan;53(1):91-7. Epub 2006 Nov 16.

40.

The therapeutic potential of the calpain family: new aspects.

Saez ME, Ramirez-Lorca R, Moron FJ, Ruiz A.

Drug Discov Today. 2006 Oct;11(19-20):917-23. Epub 2006 Sep 7. Review.

PMID:
16997142
41.

Bone morphogenetic protein 15 (BMP15) alleles predict over-response to recombinant follicle stimulation hormone and iatrogenic ovarian hyperstimulation syndrome (OHSS).

Morón FJ, de Castro F, Royo JL, Montoro L, Mira E, Sáez ME, Real LM, González A, Mañes S, Ruiz A.

Pharmacogenet Genomics. 2006 Jul;16(7):485-95.

PMID:
16788381
42.

Genetic analysis of CAV1 gene in hypertension and metabolic syndrome.

Grilo A, Fernandez ML, Beltrán M, Ramirez-Lorca R, González MA, Royo JL, Gutierrez-Tous R, Morón FJ, Couto C, Serrano-Rios M, Saez ME, Ruiz A, Real LM.

Thromb Haemost. 2006 Apr;95(4):696-701.

PMID:
16601841
43.

Specific haplotypes of the CALPAIN-5 gene are associated with polycystic ovary syndrome.

González A, Sáez ME, Aragón MJ, Galán JJ, Vettori P, Molina L, Rubio C, Real LM, Ruiz A, Ramírez-Lorca R.

Hum Reprod. 2006 Apr;21(4):943-51. Epub 2006 Jan 5.

PMID:
16396936
44.

Weighting the effect of CYP19A gene in bone mineral density of postmenopausal women.

Mendoza N, Morón FJ, Vázquez F, Quereda F, Sáez ME, Martínez-Astorquiza T, González-Pérez A, Sánchez-Borrego R, Ruiz A.

Bone. 2006 Jun;38(6):951-3; author reply 953. Epub 2005 Dec 9. No abstract available.

PMID:
16338189
45.

RET genotypes comprising specific haplotypes of polymorphic variants predispose to isolated Hirschsprung disease.

Borrego S, Ruiz A, Saez ME, Gimm O, Gao X, López-Alonso M, Hernández A, Wright FA, Antiñolo G, Eng C.

J Med Genet. 2000 Aug;37(8):572-8.

46.

A new germline mutation, R600Q, within the coding region of RET proto-oncogene: a rare polymorphism or a MEN 2 causing mutation?

Sáez ME, Ruiz A, Cebrián A, Morales F, Robledo M, Antiñolo G, Borrego S.

Hum Mutat. 2000 Jan;15(1):122. No abstract available.

PMID:
10612852
47.
48.

High prevalence of the C634Y mutation in the RET proto-oncogene in MEN 2A families in Spain.

Sánchez B, Robledo M, Biarnes J, Sáez ME, Volpini V, Benítez J, Navarro E, Ruiz A, Antiñolo G, Borrego S.

J Med Genet. 1999 Jan;36(1):68-70.

49.

Molecular analysis of the ret and GDNF genes in a family with multiple endocrine neoplasia type 2A and Hirschsprung disease.

Borrego S, Eng C, Sánchez B, Sáez ME, Navarro E, Antiñolo G.

J Clin Endocrinol Metab. 1998 Sep;83(9):3361-4.

PMID:
9745455

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