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Reducing Macro- and Microheterogeneity of N-Glycans Enables the Crystal Structure of the Lectin and EGF-Like Domains of Human L-Selectin To Be Solved at 1.9 Å Resolution.

Wedepohl S, Dernedde J, Vahedi-Faridi A, Tauber R, Saenger W, Bulut H.

Chembiochem. 2017 Jul 4;18(13):1338-1345. doi: 10.1002/cbic.201700220. Epub 2017 Jun 6.


Amylose recognition and ring-size determination of amylomaltase.

Roth C, Weizenmann N, Bexten N, Saenger W, Zimmermann W, Maier T, Sträter N.

Sci Adv. 2017 Jan 13;3(1):e1601386. doi: 10.1126/sciadv.1601386. eCollection 2017 Jan.


Crystal structures of N-acetylmannosamine kinase provide insights into enzyme activity and inhibition.

Martinez J, Nguyen LD, Hinderlich S, Zimmer R, Tauberger E, Reutter W, Saenger W, Fan H, Moniot S.

J Biol Chem. 2012 Apr 20;287(17):13656-65. doi: 10.1074/jbc.M111.318170. Epub 2012 Feb 16.


Crystal structures of receptors involved in small molecule transport across membranes.

Bulut H, Ma Q, Moniot S, Saenger W, Schneider E, Vahedi-Faridi A.

Eur J Cell Biol. 2012 Apr;91(4):318-25. doi: 10.1016/j.ejcb.2011.12.004. Epub 2012 Feb 16. Review.


Crystal structures of two solute receptors for L-cystine and L-cysteine, respectively, of the human pathogen Neisseria gonorrhoeae.

Bulut H, Moniot S, Licht A, Scheffel F, Gathmann S, Saenger W, Schneider E.

J Mol Biol. 2012 Jan 20;415(3):560-72. doi: 10.1016/j.jmb.2011.11.030. Epub 2011 Nov 23.


Structure and function of membrane-integral receptors.

Saenger W, Haucke V.

Eur J Cell Biol. 2012 Apr;91(4):225. doi: 10.1016/j.ejcb.2011.09.012. Epub 2011 Nov 21. No abstract available.


Molecular mechanism and structural basis of interactions of dipeptidyl peptidase IV with adenosine deaminase and human immunodeficiency virus type-1 transcription transactivator.

Fan H, Tansi FL, Weihofen WA, Böttcher C, Hu J, Martinez J, Saenger W, Reutter W.

Eur J Cell Biol. 2012 Apr;91(4):265-73. doi: 10.1016/j.ejcb.2011.06.001. Epub 2011 Sep 28. Review.


Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition.

von Kleist L, Stahlschmidt W, Bulut H, Gromova K, Puchkov D, Robertson MJ, MacGregor KA, Tomilin N, Pechstein A, Chau N, Chircop M, Sakoff J, von Kries JP, Saenger W, Kräusslich HG, Shupliakov O, Robinson PJ, McCluskey A, Haucke V.

Cell. 2011 Aug 5;146(3):471-84. doi: 10.1016/j.cell.2011.06.025. Erratum in: Cell. 2011 Sep 2;146(5):841. Tomlin, Nikolay [corrected to Tomilin, Nikolay].


HLA class I-associated diseases with a suspected autoimmune etiology: HLA-B27 subtypes as a model system.

Uchanska-Ziegler B, Loll B, Fabian H, Hee CS, Saenger W, Ziegler A.

Eur J Cell Biol. 2012 Apr;91(4):274-86. doi: 10.1016/j.ejcb.2011.03.003. Epub 2011 Jun 12. Review.


Receptor-transporter interactions of canonical ATP-binding cassette import systems in prokaryotes.

Schneider E, Eckey V, Weidlich D, Wiesemann N, Vahedi-Faridi A, Thaben P, Saenger W.

Eur J Cell Biol. 2012 Apr;91(4):311-7. doi: 10.1016/j.ejcb.2011.02.008. Epub 2011 May 10. Review.


The early steps of endocytosis: from cargo selection to membrane deformation.

Rao Y, Rückert C, Saenger W, Haucke V.

Eur J Cell Biol. 2012 Apr;91(4):226-33. doi: 10.1016/j.ejcb.2011.02.004. Epub 2011 Mar 31. Review.


Structural basis of cyanobacterial photosystem II Inhibition by the herbicide terbutryn.

Broser M, Glöckner C, Gabdulkhakov A, Guskov A, Buchta J, Kern J, Müh F, Dau H, Saenger W, Zouni A.

J Biol Chem. 2011 May 6;286(18):15964-72. doi: 10.1074/jbc.M110.215970. Epub 2011 Mar 2.


Loss of recognition by cross-reactive T cells and its relation to a C-terminus-induced conformational reorientation of an HLA-B*2705-bound peptide.

Loll B, Rückert C, Hee CS, Saenger W, Uchanska-Ziegler B, Ziegler A.

Protein Sci. 2011 Feb;20(2):278-90. doi: 10.1002/pro.559. Epub 2010 Dec 23.


Quasielastic small-angle neutron scattering from heavy water solutions of cyclodextrins.

Kusmin A, Lechner RE, Saenger W.

J Chem Phys. 2011 Jan 14;134(2):024518. doi: 10.1063/1.3518367.


Structural investigation of PsbO from plant and cyanobacterial photosystem II.

Slowik D, Rossmann M, Konarev PV, Irrgang KD, Saenger W.

J Mol Biol. 2011 Mar 18;407(1):125-37. doi: 10.1016/j.jmb.2011.01.013. Epub 2011 Jan 13.


Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for β-D-galactopyranose.

Licht A, Bulut H, Scheffel F, Daumke O, Wehmeier UF, Saenger W, Schneider E, Vahedi-Faridi A.

J Mol Biol. 2011 Feb 11;406(1):92-105. doi: 10.1016/j.jmb.2010.11.048. Epub 2010 Dec 17.


Regulation and structure of YahD, a copper-inducible α/β serine hydrolase of Lactococcus lactis IL1403.

Martinez J, Mancini S, Tauberger E, Weise C, Saenger W, Solioz M.

FEMS Microbiol Lett. 2011 Jan;314(1):57-66. doi: 10.1111/j.1574-6968.2010.02144.x. Epub 2010 Nov 9.


A multi-faceted approach to elucidate the crystal structure of D-ribose: similarities to protein structure determination.

Saenger W.

Angew Chem Int Ed Engl. 2010 Sep 3;49(37):6487-9. doi: 10.1002/anie.201002865. No abstract available.


Crystal structure of monomeric photosystem II from Thermosynechococcus elongatus at 3.6-a resolution.

Broser M, Gabdulkhakov A, Kern J, Guskov A, Müh F, Saenger W, Zouni A.

J Biol Chem. 2010 Aug 20;285(34):26255-62. doi: 10.1074/jbc.M110.127589. Epub 2010 Jun 17.


Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation.

Rao Y, Ma Q, Vahedi-Faridi A, Sundborger A, Pechstein A, Puchkov D, Luo L, Shupliakov O, Saenger W, Haucke V.

Proc Natl Acad Sci U S A. 2010 May 4;107(18):8213-8. doi: 10.1073/pnas.1003478107. Epub 2010 Apr 19.


Recent progress in the crystallographic studies of photosystem II.

Guskov A, Gabdulkhakov A, Broser M, Glöckner C, Hellmich J, Kern J, Frank J, Müh F, Saenger W, Zouni A.

Chemphyschem. 2010 Apr 26;11(6):1160-71. doi: 10.1002/cphc.200900901. Review.


Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2.

Pechstein A, Bacetic J, Vahedi-Faridi A, Gromova K, Sundborger A, Tomlin N, Krainer G, Vorontsova O, Schäfer JG, Owe SG, Cousin MA, Saenger W, Shupliakov O, Haucke V.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4206-11. doi: 10.1073/pnas.0911073107. Epub 2010 Feb 16.


Crystal structures of the solute receptor GacH of Streptomyces glaucescens in complex with acarbose and an acarbose homolog: comparison with the acarbose-loaded maltose-binding protein of Salmonella typhimurium.

Vahedi-Faridi A, Licht A, Bulut H, Scheffel F, Keller S, Wehmeier UF, Saenger W, Schneider E.

J Mol Biol. 2010 Apr 2;397(3):709-23. doi: 10.1016/j.jmb.2010.01.054. Epub 2010 Feb 2.


Molecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.

Kahlfeldt N, Vahedi-Faridi A, Koo SJ, Schäfer JG, Krainer G, Keller S, Saenger W, Krauss M, Haucke V.

J Biol Chem. 2010 Jan 22;285(4):2734-49. doi: 10.1074/jbc.M109.074906. Epub 2009 Nov 10.


Three-dimensional structure of N-terminal domain of DnaB helicase and helicase-primase interactions in Helicobacter pylori.

Kashav T, Nitharwal R, Abdulrehman SA, Gabdoulkhakov A, Saenger W, Dhar SK, Gourinath S.

PLoS One. 2009 Oct 20;4(10):e7515. doi: 10.1371/journal.pone.0007515.


Probing the accessibility of the Mn(4)Ca cluster in photosystem II: channels calculation, noble gas derivatization, and cocrystallization with DMSO.

Gabdulkhakov A, Guskov A, Broser M, Kern J, Müh F, Saenger W, Zouni A.

Structure. 2009 Sep 9;17(9):1223-34. doi: 10.1016/j.str.2009.07.010.


Crystal structure of the antitoxin-toxin protein complex RelB-RelE from Methanococcus jannaschii.

Francuski D, Saenger W.

J Mol Biol. 2009 Nov 6;393(4):898-908. doi: 10.1016/j.jmb.2009.08.048. Epub 2009 Aug 25.


Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens.

Kumar P, Vahedi-Faridi A, Saenger W, Merino E, López de Castro JA, Uchanska-Ziegler B, Ziegler A.

J Biol Chem. 2009 Oct 23;284(43):29784-97. doi: 10.1074/jbc.M109.038497. Epub 2009 Jul 18.


Preferential pathways for light-trapping involving beta-ligated chlorophylls.

Balaban TS, Braun P, Hättig C, Hellweg A, Kern J, Saenger W, Zouni A.

Biochim Biophys Acta. 2009 Oct;1787(10):1254-65. doi: 10.1016/j.bbabio.2009.05.010. Epub 2009 May 27.


Structure and function of primase RepB' encoded by broad-host-range plasmid RSF1010 that replicates exclusively in leading-strand mode.

Geibel S, Banchenko S, Engel M, Lanka E, Saenger W.

Proc Natl Acad Sci U S A. 2009 May 12;106(19):7810-5. doi: 10.1073/pnas.0902910106. Epub 2009 Apr 24.


Cyanobacterial photosystem II at 2.9-A resolution and the role of quinones, lipids, channels and chloride.

Guskov A, Kern J, Gabdulkhakov A, Broser M, Zouni A, Saenger W.

Nat Struct Mol Biol. 2009 Mar;16(3):334-42. doi: 10.1038/nsmb.1559. Epub 2009 Feb 15.


Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity.

Kumar P, Vahedi-Faridi A, Saenger W, Ziegler A, Uchanska-Ziegler B.

Protein Sci. 2009 Jan;18(1):37-49. doi: 10.1002/pro.4.


Modeling of variant copies of subunit D1 in the structure of photosystem II from Thermosynechococcus elongatus.

Loll B, Broser M, Kós PB, Kern J, Biesiadka J, Vass I, Saenger W, Zouni A.

Biol Chem. 2008 May;389(5):609-17.


Native and methylated cyclodextrins with positive and negative solubility coefficients in water studied by SAXS and SANS.

Kusmin A, Lechner RE, Kammel M, Saenger W.

J Phys Chem B. 2008 Oct 16;112(41):12888-98. doi: 10.1021/jp802031w. Epub 2008 Sep 18.


Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes.

Beltrami A, Rossmann M, Fiorillo MT, Paladini F, Sorrentino R, Saenger W, Kumar P, Ziegler A, Uchanska-Ziegler B.

J Biol Chem. 2008 Oct 3;283(40):27189-99. doi: 10.1074/jbc.M802818200. Epub 2008 Jul 23.


Specific binding of divalent metal ions to tetracycline and to the Tet repressor/tetracycline complex.

Palm GJ, Lederer T, Orth P, Saenger W, Takahashi M, Hillen W, Hinrichs W.

J Biol Inorg Chem. 2008 Sep;13(7):1097-110. doi: 10.1007/s00775-008-0395-2. Epub 2008 Jun 12.


Streptococcus pyogenes pSM19035 requires dynamic assembly of ATP-bound ParA and ParB on parS DNA during plasmid segregation.

Pratto F, Cicek A, Weihofen WA, Lurz R, Saenger W, Alonso JC.

Nucleic Acids Res. 2008 Jun;36(11):3676-89. doi: 10.1093/nar/gkn170. Epub 2008 May 13.


Crystal structures of human saposins C andD: implications for lipid recognition and membrane interactions.

Rossmann M, Schultz-Heienbrok R, Behlke J, Remmel N, Alings C, Sandhoff K, Saenger W, Maier T.

Structure. 2008 May;16(5):809-17. doi: 10.1016/j.str.2008.02.016.


Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABAA receptor gamma2 subunit.

Kittler JT, Chen G, Kukhtina V, Vahedi-Faridi A, Gu Z, Tretter V, Smith KR, McAinsh K, Arancibia-Carcamo IL, Saenger W, Haucke V, Yan Z, Moss SJ.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3616-21. doi: 10.1073/pnas.0707920105. Epub 2008 Feb 27.


Expression, purification and preliminary X-ray crystallographic analysis of the human major histocompatibility antigen HLA-B*1402 in complex with a viral peptide and with a self-peptide.

Kumar P, Vahedi-Faridi A, Merino E, López de Castro JA, Volz A, Ziegler A, Saenger W, Uchanska-Ziegler B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jul 1;63(Pt 7):631-4. Epub 2007 Jun 29.


Structure of full-length transcription regulator CcpA in the apo form.

Loll B, Saenger W, Biesiadka J.

Biochim Biophys Acta. 2007 Jun;1774(6):732-6. Epub 2007 Apr 18.


Structure of the Mn4-Ca cluster as derived from X-ray diffraction.

Kern J, Biesiadka J, Loll B, Saenger W, Zouni A.

Photosynth Res. 2007 Jun;92(3):389-405. Epub 2007 May 11. Review.


Structure of the transcription regulator CcpA from Lactococcus lactis.

Loll B, Kowalczyk M, Alings C, Chieduch A, Bardowski J, Saenger W, Biesiadka J.

Acta Crystallogr D Biol Crystallogr. 2007 Apr;63(Pt 4):431-6. Epub 2007 Mar 16.


Lipids in photosystem II: interactions with protein and cofactors.

Loll B, Kern J, Saenger W, Zouni A, Biesiadka J.

Biochim Biophys Acta. 2007 Jun;1767(6):509-19. Epub 2007 Jan 4.


Function of two beta-carotenes near the D1 and D2 proteins in photosystem II dimers.

Ishikita H, Loll B, Biesiadka J, Kern J, Irrgang KD, Zouni A, Saenger W, Knapp EW.

Biochim Biophys Acta. 2007 Jan;1767(1):79-87. Epub 2006 Oct 18.


Where water is oxidized to dioxygen: structure of the photosynthetic Mn4Ca cluster.

Yano J, Kern J, Sauer K, Latimer MJ, Pushkar Y, Biesiadka J, Loll B, Saenger W, Messinger J, Zouni A, Yachandra VK.

Science. 2006 Nov 3;314(5800):821-5.


Structures of human N-Acetylglucosamine kinase in two complexes with N-Acetylglucosamine and with ADP/glucose: insights into substrate specificity and regulation.

Weihofen WA, Berger M, Chen H, Saenger W, Hinderlich S.

J Mol Biol. 2006 Dec 1;364(3):388-99. Epub 2006 Sep 3.


Saposin A mobilizes lipids from low cholesterol and high bis(monoacylglycerol)phosphate-containing membranes: patient variant Saposin A lacks lipid extraction capacity.

Locatelli-Hoops S, Remmel N, Klingenstein R, Breiden B, Rossocha M, Schoeniger M, Koenigs C, Saenger W, Sandhoff K.

J Biol Chem. 2006 Oct 27;281(43):32451-60. Epub 2006 Aug 12.

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