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Items: 1 to 50 of 119

1.

Does the duration to bipolar hip arthroplasty for femoral neck fracture influence on postoperative muscular strength?

Chinzei N, Noda M, Matsushita T, Inui A, Osawa S, Okimura K, Takahashi M, Saegusa Y.

Eur J Orthop Surg Traumatol. 2020 Feb;30(2):251-256. doi: 10.1007/s00590-019-02545-w. Epub 2019 Sep 6.

PMID:
31493025
2.

Developmental exposure of citreoviridin transiently affects hippocampal neurogenesis targeting multiple regulatory functions in mice.

Nakajima K, Masubuchi Y, Ito Y, Inohana M, Takino M, Saegusa Y, Yoshida T, Sugita-Konishi Y, Shibutani M.

Food Chem Toxicol. 2018 Oct;120:590-602. doi: 10.1016/j.fct.2018.07.051. Epub 2018 Jul 30.

3.

Dynamic finite element analysis of implants for femoral neck fractures simulating walking.

Noda M, Nakamura Y, Adachi K, Saegusa Y, Takahashi M.

J Orthop Surg (Hong Kong). 2018 May-Aug;26(2):2309499018777899. doi: 10.1177/2309499018777899.

PMID:
29860916
4.

Developmental Exposure to Aluminum Chloride Irreversibly Affects Postnatal Hippocampal Neurogenesis Involving Multiple Functions in Mice.

Inohana M, Eguchi A, Nakamura M, Nagahara R, Onda N, Nakajima K, Saegusa Y, Yoshida T, Shibutani M.

Toxicol Sci. 2018 Jul 1;164(1):264-277. doi: 10.1093/toxsci/kfy081.

5.

Substituent Effects at the β-Positions of the Nonfused Pyrroles in a Quadruply Fused Porphyrin on the Structure and Optical and Electrochemical Properties.

Saegusa Y, Ishizuka T, Kojima T.

Inorg Chem. 2018 Feb 5;57(3):1106-1115. doi: 10.1021/acs.inorgchem.7b02551. Epub 2018 Jan 23.

PMID:
29360352
6.

NH Tautomerism of a Quadruply Fused Porphyrin: Rigid Fused Structure Delays the Proton Transfer.

Saegusa Y, Ishizuka T, Shiota Y, Yoshizawa K, Kojima T.

J Phys Chem B. 2018 Jan 11;122(1):316-327. doi: 10.1021/acs.jpcb.7b10945. Epub 2017 Dec 27.

PMID:
29224345
7.

Decreased postoperative gluteus medius muscle cross-sectional area measured by computed tomography scan in patients with intertrochanteric fractures nailing.

Noda M, Saegusa Y, Takahashi M, Takada Y, Fujita M, Shinohara I.

J Orthop Surg (Hong Kong). 2017 Sep-Dec;25(3):2309499017727943. doi: 10.1177/2309499017727943.

PMID:
28920547
8.

Downregulation of UBE2E2 in rat liver cells after hepatocarcinogen treatment facilitates cell proliferation and slowing down of DNA damage response in GST-P-expressing preneoplastic lesions.

Mizukami S, Watanabe Y, Saegusa Y, Nakajima K, Ito Y, Masubuchi Y, Yoshida T, Shibutani M.

Toxicol Appl Pharmacol. 2017 Nov 1;334:207-216. doi: 10.1016/j.taap.2017.09.005. Epub 2017 Sep 9.

PMID:
28899750
9.

Diminished abductor muscular strength in patients with valgus-impacted femoral neck fractures treated by internal fixation: Clinical study and biomechanical considerations.

Noda M, Saegusa Y, Takahashi M, Kuroda Y, Takada Y, Yoshikawa C, Wakabayashi M, Adachi K, Nakamura Y.

J Orthop Surg (Hong Kong). 2017 May-Aug;25(2):2309499017716070. doi: 10.1177/2309499017716070.

PMID:
28639532
10.

Comparison of Post-Operative Muscular Strength Between Gamma Nailing and Hemiarthroplasty System in Femoral Intertrochanteric Fractures.

Noda M, Saegusa Y, Takahashi M, Noguchi C, Yoshikawa C, Mikami H, Gotouda A.

Open Orthop J. 2017 Mar 31;11:255-262. doi: 10.2174/1874325001711010255. eCollection 2017.

11.

Mashiningan Improves Opioid-Induced Constipation in Rats by Activating Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel.

Harada Y, Iizuka S, Saegusa Y, Mogami S, Fujitsuka N, Hattori T.

J Pharmacol Exp Ther. 2017 Jul;362(1):78-84. doi: 10.1124/jpet.117.240630. Epub 2017 May 2.

PMID:
28465373
12.

Non-neoplastic lesions found only in the two-year bioassays but not in shorter toxicity studies of rats.

Nonaka M, Amakasu K, Saegusa Y, Naota M, Nishimura T, Ogawa K, Nishikawa A.

Regul Toxicol Pharmacol. 2017 Jun;86:199-204. doi: 10.1016/j.yrtph.2017.03.008. Epub 2017 Mar 10.

PMID:
28288808
13.

Acid-Base Properties of a Freebase Form of a Quadruply Ring-Fused Porphyrin-Stepwise Protonation Induced by Rigid Ring-Fused Structure.

Saegusa Y, Ishizuka T, Shiota Y, Yoshizawa K, Kojima T.

J Org Chem. 2017 Jan 6;82(1):322-330. doi: 10.1021/acs.joc.6b02419. Epub 2016 Dec 23.

PMID:
27966350
14.

Biomechanical Study Using the Finite Element Method of Internal Fixation in Pauwels Type III Vertical Femoral Neck Fractures.

Noda M, Saegusa Y, Takahashi M, Tezuka D, Adachi K, Naoi K.

Arch Trauma Res. 2015 Aug 26;4(3):e23167. doi: 10.5812/atr.23167. eCollection 2015 Sep.

15.

Influence of Aging and Gender Differences on Feeding Behavior and Ghrelin-Related Factors during Social Isolation in Mice.

Yamada C, Saegusa Y, Nahata M, Sadakane C, Hattori T, Takeda H.

PLoS One. 2015 Oct 8;10(10):e0140094. doi: 10.1371/journal.pone.0140094. eCollection 2015.

16.

cAMP controls the balance of the propulsive forces generated by the two flagella of Chlamydomonas.

Saegusa Y, Yoshimura K.

Cytoskeleton (Hoboken). 2015 Aug;72(8):412-21. doi: 10.1002/cm.21235. Epub 2015 Aug 22.

PMID:
26257199
17.

A New Strategy Using Rikkunshito to Treat Anorexia and Gastrointestinal Dysfunction.

Saegusa Y, Hattori T, Nahata M, Yamada C, Takeda H.

Evid Based Complement Alternat Med. 2015;2015:364260. doi: 10.1155/2015/364260. Epub 2015 May 3. Review.

18.

Ring-fused porphyrins: extension of π-conjugation significantly affects the aromaticity and optical properties of the porphyrin π-systems and the Lewis acidity of the central metal ions.

Saegusa Y, Ishizuka T, Komamura K, Shimizu S, Kotani H, Kobayashi N, Kojima T.

Phys Chem Chem Phys. 2015 Jun 14;17(22):15001-11. doi: 10.1039/c5cp01420d.

PMID:
25986941
19.

Native valve endocarditis caused by Neisseria elongata Subsp. nitroreducens.

Osuka H, Ichiki A, Yamamoto M, Kawahata D, Saegusa Y, Oishi T, Okubo S, Hitomi S.

Intern Med. 2015;54(7):853-6. doi: 10.2169/internalmedicine.54.2738. Epub 2015 Apr 1.

20.

Supramolecular interaction of fullerenes with a curved π-surface of a monomeric quadruply ring-fused porphyrin.

Saegusa Y, Ishizuka T, Kojima T, Mori S, Kawano M, Kojima T.

Chemistry. 2015 Mar 27;21(14):5302-6. doi: 10.1002/chem.201500389. Epub 2015 Mar 3.

PMID:
25736095
21.

Serotonin 2C receptor contributes to gender differences in stress-induced hypophagia in aged mice.

Yamada C, Sadakane C, Nahata M, Saegusa Y, Nakagawa K, Okubo N, Ohnishi S, Hattori T, Takeda H.

Psychoneuroendocrinology. 2015 May;55:81-93. doi: 10.1016/j.psyneuen.2015.02.006. Epub 2015 Feb 18.

22.

Administration of exogenous acylated ghrelin or rikkunshito, an endogenous ghrelin enhancer, improves the decrease in postprandial gastric motility in an acute restraint stress mouse model.

Nahata M, Saegusa Y, Sadakane C, Yamada C, Nakagawa K, Okubo N, Ohnishi S, Hattori T, Sakamoto N, Takeda H.

Neurogastroenterol Motil. 2014 Jun;26(6):821-31. doi: 10.1111/nmo.12336. Epub 2014 Mar 30.

23.

Rikkunshito, a Japanese kampo medicine, ameliorates decreased feeding behavior via ghrelin and serotonin 2B receptor signaling in a novelty stress murine model.

Yamada C, Saegusa Y, Nakagawa K, Ohnishi S, Muto S, Nahata M, Sadakane C, Hattori T, Sakamoto N, Takeda H.

Biomed Res Int. 2013;2013:792940. doi: 10.1155/2013/792940. Epub 2013 Oct 29.

24.

A new treatment for avulsion fracture of the calcaneus using an Ilizarov external fixator.

Takahashi M, Noda M, Saegusa Y.

Injury. 2013 Nov;44(11):1640-3. doi: 10.1016/j.injury.2013.04.019. Epub 2013 Jun 2.

PMID:
23735503
25.

Multiply-fused porphyrins--effects of extended π-conjugation on the optical and electrochemical properties.

Ishizuka T, Saegusa Y, Shiota Y, Ohtake K, Yoshizawa K, Kojima T.

Chem Commun (Camb). 2013 Jul 7;49(53):5939-41. doi: 10.1039/c3cc42831a.

PMID:
23715087
26.

Changes in ghrelin-related factors in gastroesophageal reflux disease in rats.

Nahata M, Saegusa Y, Harada Y, Tsuchiya N, Hattori T, Takeda H.

Gastroenterol Res Pract. 2013;2013:504816. doi: 10.1155/2013/504816. Epub 2013 Apr 4.

27.

Serotonin 2C receptor antagonism ameliorates novelty-induced hypophagia in aged mice.

Nahata M, Muto S, Nakagawa K, Ohnishi S, Sadakane C, Saegusa Y, Iizuka S, Hattori T, Asaka M, Takeda H.

Psychoneuroendocrinology. 2013 Oct;38(10):2051-64. doi: 10.1016/j.psyneuen.2013.03.014. Epub 2013 Apr 11.

28.
29.

Long-term results of intertrochanteric varus osteotomy for the dysplastic hip.

Nishiyama T, Saegusa Y, Fujishiro T, Hayashi S, Kanzaki N, Hashimoto S, Kurosaka M.

Hip Int. 2012 Nov-Dec;22(6):628-32. doi: 10.5301/HIP.2012.10351.

PMID:
23233182
30.

Rikkunshito as a ghrelin enhancer.

Takeda H, Muto S, Nakagawa K, Ohnishi S, Sadakane C, Saegusa Y, Nahata M, Hattori T, Asaka M.

Methods Enzymol. 2012;514:333-51. doi: 10.1016/B978-0-12-381272-8.00021-0.

PMID:
22975063
31.

A case of the geniculate artery pseudoaneurysm after total knee arthroplasty: search for preventive measures by evaluation of arterial anatomy of cadaver knees.

Noda M, Saegusa Y, Takahashi M, Hirata Y.

Knee Surg Sports Traumatol Arthrosc. 2013 Dec;21(12):2721-4. doi: 10.1007/s00167-012-2109-0. Epub 2012 Jun 23.

PMID:
22729807
32.

Impaired ghrelin signaling is associated with gastrointestinal dysmotility in rats with gastroesophageal reflux disease.

Nahata M, Muto S, Oridate N, Ohnishi S, Nakagawa K, Sadakane C, Saegusa Y, Hattori T, Asaka M, Takeda H.

Am J Physiol Gastrointest Liver Physiol. 2012 Jul;303(1):G42-53. doi: 10.1152/ajpgi.00462.2011. Epub 2012 Apr 19.

33.

Transient aberration of neuronal development in the hippocampal dentate gyrus after developmental exposure to brominated flame retardants in rats.

Saegusa Y, Fujimoto H, Woo GH, Ohishi T, Wang L, Mitsumori K, Nishikawa A, Shibutani M.

Arch Toxicol. 2012 Sep;86(9):1431-42. doi: 10.1007/s00204-012-0824-4. Epub 2012 Mar 14.

PMID:
22415764
34.

Surgical treatment for permanent dislocation of the patella in adults.

Noda M, Saegusa Y, Kashiwagi N, Seto Y.

Orthopedics. 2011 Dec 6;34(12):e948-51. doi: 10.3928/01477447-20111021-27.

PMID:
22146216
35.

Does the location of the entry point affect the reduction of proximal humeral fractures? A cadaveric study.

Noda M, Saegusa Y, Maeda T.

Injury. 2011 Sep;42 Suppl 4:S35-8. doi: 10.1016/S0020-1383(11)70010-9.

PMID:
21939801
36.

10-Gingerol, a component of rikkunshito, improves cisplatin-induced anorexia by inhibiting acylated ghrelin degradation.

Sadakane C, Muto S, Nakagawa K, Ohnishi S, Saegusa Y, Nahata M, Hattori T, Asaka M, Takeda H.

Biochem Biophys Res Commun. 2011 Sep 2;412(3):506-11. doi: 10.1016/j.bbrc.2011.08.002. Epub 2011 Aug 9.

PMID:
21846463
37.

Decreased plasma ghrelin contributes to anorexia following novelty stress.

Saegusa Y, Takeda H, Muto S, Nakagawa K, Ohnishi S, Sadakane C, Nahata M, Hattori T, Asaka M.

Am J Physiol Endocrinol Metab. 2011 Oct;301(4):E685-96. doi: 10.1152/ajpendo.00121.2011. Epub 2011 Jun 28.

38.

Decreased motility of the lower esophageal sphincter in a rat model of gastroesophageal reflux disease may be mediated by reductions of serotonin and acetylcholine signaling.

Saegusa Y, Takeda H, Muto S, Oridate N, Nakagawa K, Sadakane C, Nahata M, Harada Y, Iizuka M, Hattori T, Asaka M.

Biol Pharm Bull. 2011;34(5):704-11.

39.

Effect of TJN-331 on anti-Thy1 nephritis in rats via inhibition of transforming growth factor-β1 production.

Saegusa Y, Sadakane C, Koseki J, Hasegawa Y, Shindo S, Maruyama H, Kase Y, Takeda S, Takeda H, Hattori T.

Biol Pharm Bull. 2010;33(10):1710-5.

40.

Spermatocytic seminoma with neuroectodermal differentiation and sertoli cell tumor in a dog.

Saegusa Y, Hayashi H, Taniai E, Imaoka M, Ohishi T, Wang L, Mitsumori K, Shibutani M.

Vet Pathol. 2011 Sep;48(5):1024-8. doi: 10.1177/0300985810385150. Epub 2010 Oct 7.

PMID:
20930104
41.

(E)-N-[(3,4-dimethoxyphenethyl)]-N-methyl-3-(3-pyridyl)-2-propenamide (TJN-331) inhibits mesangial expansion in experimental IgA nephropathy in ddY mice.

Saegusa Y, Sadakane C, Koseki J, Hasegawa Y, Shindo S, Takeda S, Takeda H, Hattori T.

Clin Exp Nephrol. 2010 Dec;14(6):528-35. doi: 10.1007/s10157-010-0338-4. Epub 2010 Sep 4.

PMID:
20814808
42.

TJN-331 improves anti-glomerular basement membrane nephritis by inhibiting the production of intraglomerular transforming growth factor-beta1.

Saegusa Y, Sadakane C, Koseki J, Hasegawa Y, Shindo S, Maruyama H, Takeda S, Takeda H, Hattori T.

Biol Pharm Bull. 2010;33(8):1349-54.

43.

Immunohistochemical analyses at the late stage of tumor promotion by oxfendazole in a rat hepatocarcinogenesis model.

Dewa Y, Nishimura J, Jin M, Kawai M, Saegusa Y, Kenmochi S, Shimamoto K, Harada T, Shibutani M, Mitsumori K.

Arch Toxicol. 2011 Feb;85(2):155-62. doi: 10.1007/s00204-010-0557-1. Epub 2010 May 26.

PMID:
20502879
44.

Sustained production of Reelin-expressing interneurons in the hippocampal dentate hilus after developmental exposure to anti-thyroid agents in rats.

Saegusa Y, Woo GH, Fujimoto H, Kemmochi S, Shimamoto K, Hirose M, Mitsumori K, Nishikawa A, Shibutani M.

Reprod Toxicol. 2010 Jul;29(4):407-14. doi: 10.1016/j.reprotox.2010.03.006. Epub 2010 Mar 27.

PMID:
20347957
45.

Vulnerable sites and changes in mucin in the rat small intestine after non-steroidal anti-inflammatory drugs administration.

Iwai T, Ichikawa T, Kida M, Goso Y, Saegusa Y, Okayasu I, Saigenji K, Ishihara K.

Dig Dis Sci. 2010 Dec;55(12):3369-76. doi: 10.1007/s10620-010-1185-6. Epub 2010 Mar 19.

PMID:
20300842
46.

The threshold dose for liver tumor promoting effects of dicyclanil in ICR mice.

Jin M, Dewa Y, Kawai M, Nishimura J, Saegusa Y, Kemmochi S, Harada T, Shibutani M, Mitsumori K.

J Toxicol Sci. 2010 Feb;35(1):69-78.

47.

Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice.

Kawai M, Saegusa Y, Dewa Y, Nishimura J, Kemmochi S, Harada T, Ishii Y, Umemura T, Shibutani M, Mitsumori K.

Arch Toxicol. 2010 Feb;84(2):155-64. doi: 10.1007/s00204-009-0498-8. Epub 2010 Jan 26.

PMID:
20101389
48.

Cytokeratin 8/18 is a useful immunohistochemical marker for hepatocellular proliferative lesions in mice.

Kawai M, Saegusa Y, Kemmochi S, Harada T, Shimamoto K, Shibutani M, Mitsumori K.

J Vet Med Sci. 2010 Mar;72(3):263-9. Epub 2009 Dec 25.

49.

Antioxidant enzymatically modified isoquercitrin or melatonin supplementation reduces oxidative stress-mediated hepatocellular tumor promotion of oxfendazole in rats.

Nishimura J, Saegusa Y, Dewa Y, Jin M, Kawai M, Kemmochi S, Harada T, Hayashi SM, Shibutani M, Mitsumori K.

Arch Toxicol. 2010 Feb;84(2):143-53. doi: 10.1007/s00204-009-0497-9. Epub 2009 Dec 22.

PMID:
20033131
50.

No Modifying Effect of Antioxidant N-Acetyl-L-Cysteine on Fenofibrate-induced Hepatocarcinogenesis in Rats.

Nishimura J, Dewa Y, Jin M, Saegusa Y, Kawai M, Kemmochi S, Shimamoto K, Harada T, Itoh T, Shima T, Shibutani M, Mitsumori K.

J Toxicol Pathol. 2009 Dec;22(4):255-61. doi: 10.1293/tox.22.255. Epub 2009 Dec 21.

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