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Items: 1 to 50 of 279

1.

Exome sequencing in multiple sclerosis families identifies 12 candidate genes and nominates biological pathways for the genesis of disease.

Vilariño-Güell C, Zimprich A, Martinelli-Boneschi F, Herculano B, Wang Z, Matesanz F, Urcelay E, Vandenbroeck K, Leyva L, Gris D, Massaad C, Quandt JA, Traboulsee AL, Encarnacion M, Bernales CQ, Follett J, Yee IM, Criscuoli MG, Deutschländer A, Reinthaler EM, Zrzavy T, Mascia E, Zauli A, Esposito F, Alcina A, Izquierdo G, Espino-Paisán L, Mena J, Antigüedad A, Urbaneja-Romero P, Ortega-Pinazo J, Song W, Sadovnick AD.

PLoS Genet. 2019 Jun 6;15(6):e1008180. doi: 10.1371/journal.pgen.1008180. eCollection 2019 Jun.

2.

TPP2 mutation associated with sterile brain inflammation mimicking MS.

Reinthaler EM, Graf E, Zrzavy T, Wieland T, Hotzy C, Kopecky C, Pferschy S, Schmied C, Leutmezer F, Keilani M, Lill CM, Hoffjan S, Epplen JT, Zettl UK, Hecker M, Deutschländer A, Meuth SG, Ahram M, Mustafa B, El-Khateeb M, Vilariño-Güell C, Sadovnick AD, Zimprich F, Tomkinson B, Strom T, Kristoferitsch W, Lassmann H, Zimprich A.

Neurol Genet. 2018 Nov 13;4(6):e285. doi: 10.1212/NXG.0000000000000285. eCollection 2018 Dec.

3.

Increased mean R2* in the deep gray matter of multiple sclerosis patients: Have we been measuring atrophy?

Hernández-Torres E, Wiggermann V, Machan L, Sadovnick AD, Li DKB, Traboulsee A, Hametner S, Rauscher A.

J Magn Reson Imaging. 2019 Jul;50(1):201-208. doi: 10.1002/jmri.26561. Epub 2018 Dec 4.

PMID:
30511803
4.

Analysis of Canadian multiple sclerosis patients does not support a role for FKBP6 in disease.

Vilariño-Güell C, Encarnacion M, Bernales CQ, Sadovnick AD.

Mult Scler. 2019 Jun;25(7):1011-1013. doi: 10.1177/1352458518803789. Epub 2018 Oct 9. No abstract available.

PMID:
30298791
5.

Safety and efficacy of venoplasty in MS: A randomized, double-blind, sham-controlled phase II trial.

Traboulsee AL, Machan L, Girard JM, Raymond J, Vosoughi R, Hardy BW, Emond F, Gariepy JL, Bone JN, Siskin G, Klass D, Isserow S, Illes J, Sadovnick AD, Li DK.

Neurology. 2018 Oct 30;91(18):e1660-e1668. doi: 10.1212/WNL.0000000000006423. Epub 2018 Sep 28.

6.

Analysis of NOD-like receptor NLRP1 in multiple sclerosis families.

Bernales CQ, Encarnacion M, Criscuoli MG, Yee IM, Traboulsee AL, Sadovnick AD, Vilariño-Güell C.

Immunogenetics. 2018 Mar;70(3):205-207. doi: 10.1007/s00251-017-1034-2. Epub 2017 Oct 7.

PMID:
28988323
7.

Multiple sclerosis in First Nations Canadians: A pilot comparison study.

Marrie RA, Hall N, Sadovnick AD.

Mult Scler J Exp Transl Clin. 2016 Aug 29;2:2055217316666093. doi: 10.1177/2055217316666093. eCollection 2016 Jan-Dec.

8.

Genetic modifiers of multiple sclerosis progression, severity and onset.

Sadovnick AD, Traboulsee AL, Zhao Y, Bernales CQ, Encarnacion M, Ross JP, Yee IM, Criscuoli MG, Vilariño-Güell C.

Clin Immunol. 2017 Jul;180:100-105. doi: 10.1016/j.clim.2017.05.009. Epub 2017 May 10.

PMID:
28501589
9.

Common genetic etiology between "multiple sclerosis-like" single-gene disorders and familial multiple sclerosis.

Traboulsee AL, Sadovnick AD, Encarnacion M, Bernales CQ, Yee IM, Criscuoli MG, Vilariño-Güell C.

Hum Genet. 2017 Jun;136(6):705-714. doi: 10.1007/s00439-017-1784-9. Epub 2017 Mar 23.

PMID:
28337550
10.

Purinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis.

Sadovnick AD, Gu BJ, Traboulsee AL, Bernales CQ, Encarnacion M, Yee IM, Criscuoli MG, Huang X, Ou A, Milligan CJ, Petrou S, Wiley JS, Vilariño-Güell C.

Hum Mutat. 2017 Jun;38(6):736-744. doi: 10.1002/humu.23218. Epub 2017 Apr 13.

11.

Patient-Reported Benefits of Extracranial Venous Therapy: British Columbia CCSVI Registry.

Sadovnick AD, Yee IM, Attwell-Pope K, Keyes G, Kipp L, Traboulsee AL.

Can J Neurol Sci. 2017 May;44(3):246-254. doi: 10.1017/cjn.2017.27. Epub 2017 Mar 8.

PMID:
28270250
12.

Prevalence of Extracranial Venous Narrowing on Magnetic Resonance Venography Is Similar in People With Multiple Sclerosis, Their Siblings, and Unrelated Healthy Controls: A Blinded, Case-Control Study.

Martin N, Traboulsee AL, Machan L, Klass D, Ellchuk T, Zhao Y, Knox KB, Kopriva D, Lala S, Nickel D, Otani R, Perera WR, Rauscher A, Sadovnick AD, Szkup P, Li DK.

Can Assoc Radiol J. 2017 May;68(2):202-209. doi: 10.1016/j.carj.2016.07.002. Epub 2016 Nov 22.

PMID:
27887935
13.

Nuclear Receptor NR1H3 in Familial Multiple Sclerosis.

Wang Z, Sadovnick AD, Traboulsee AL, Ross JP, Bernales CQ, Encarnacion M, Yee IM, de Lemos M, Greenwood T, Lee JD, Wright G, Ross CJ, Zhang S, Song W, Vilariño-Güell C.

Neuron. 2016 Oct 19;92(2):555. doi: 10.1016/j.neuron.2016.09.028. No abstract available.

14.

Case-Control Studies Are Not Familial Studies.

Wang Z, Sadovnick AD, Traboulsee AL, Ross JP, Bernales CQ, Encarnacion M, Yee IM, de Lemos M, Greenwood T, Lee JD, Wright G, Ross CJ, Zhang S, Song W, Vilariño-Güell C.

Neuron. 2016 Oct 19;92(2):339-341. doi: 10.1016/j.neuron.2016.09.053.

15.

Editorial Note to:Nuclear Receptor NR1H3 in Familial Multiple Sclerosis.

Wang Z, Sadovnick AD, Traboulsee AL, Ross JP, Bernales CQ, Encarnacion M, Yee IM, de Lemos M, Greenwood T, Lee JD, Wright G, Ross CJ, Zhang S, Song W, Vilariño-Güell C.

Neuron. 2016 Oct 19;92(2):331-332. doi: 10.1016/j.neuron.2016.10.008. No abstract available.

16.

Nuclear Receptor NR1H3 in Familial Multiple Sclerosis.

Wang Z, Sadovnick AD, Traboulsee AL, Ross JP, Bernales CQ, Encarnacion M, Yee IM, de Lemos M, Greenwood T, Lee JD, Wright G, Ross CJ, Zhang S, Song W, Vilariño-Güell C.

Neuron. 2016 Jun 1;90(5):948-54. doi: 10.1016/j.neuron.2016.04.039. Erratum in: Neuron. 2016 Oct 19;92(2):555.

17.

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients.

Sadovnick AD, Traboulsee AL, Bernales CQ, Ross JP, Forwell AL, Yee IM, Guillot-Noel L, Fontaine B, Cournu-Rebeix I, Alcina A, Fedetz M, Izquierdo G, Matesanz F, Hilven K, Dubois B, Goris A, Astobiza I, Alloza I, Antigüedad A, Vandenbroeck K, Akkad DA, Aktas O, Blaschke P, Buttmann M, Chan A, Epplen JT, Gerdes LA, Kroner A, Kubisch C, Kümpfel T, Lohse P, Rieckmann P, Zettl UK, Zipp F, Bertram L, Lill CM, Fernandez O, Urbaneja P, Leyva L, Alvarez-Cermeño JC, Arroyo R, Garagorri AM, García-Martínez A, Villar LM, Urcelay E, Malhotra S, Montalban X, Comabella M, Berger T, Fazekas F, Reindl M, Schmied MC, Zimprich A, Vilariño-Güell C.

G3 (Bethesda). 2016 Jul 7;6(7):2073-9. doi: 10.1534/g3.116.030841.

18.

Analysis of CH25H in multiple sclerosis and neuromyelitis optica.

Forwell AL, Bernales CQ, Ross JP, Yee IM, Encarnacion M, Lee JD, Sadovnick AD, Traboulsee AL, Vilariño-Güell C.

J Neuroimmunol. 2016 Feb 15;291:70-2. doi: 10.1016/j.jneuroim.2015.12.014. Epub 2015 Dec 31.

19.

Multiple sclerosis in men: management considerations.

Bove R, McHenry A, Hellwig K, Houtchens M, Razaz N, Smyth P, Tremlett H, Sadovnick AD, Rintell D.

J Neurol. 2016 Jul;263(7):1263-73. doi: 10.1007/s00415-015-8005-z. Epub 2016 Jan 2. Review.

PMID:
26725085
20.

Orientation Dependent MR Signal Decay Differentiates between People with MS, Their Asymptomatic Siblings and Unrelated Healthy Controls.

Hernández-Torres E, Wiggermann V, Hametner S, Baumeister TR, Sadovnick AD, Zhao Y, Machan L, Li DK, Traboulsee A, Rauscher A.

PLoS One. 2015 Oct 21;10(10):e0140956. doi: 10.1371/journal.pone.0140956. eCollection 2015.

21.

Viral exposures and MS outcome in a prospective cohort of children with acquired demyelination.

Makhani N, Banwell B, Tellier R, Yea C, McGovern S, O'Mahony J, Ahorro JM, Arnold D, Sadovnick AD, Marrie RA, Bar-Or A; Canadian Pediatric Demyelinating Disease Network.

Mult Scler. 2016 Mar;22(3):385-8. doi: 10.1177/1352458515595876. Epub 2015 Jul 21.

PMID:
26199356
22.

Incidence of Multiple Sclerosis and Related Disorders in Asian Populations of British Columbia.

Lee JD, Guimond C, Yee IM, Vilariño-Güell C, Wu ZY, Traboulsee AL, Sadovnick AD.

Can J Neurol Sci. 2015 Jul;42(4):235-41. doi: 10.1017/cjn.2015.36. Epub 2015 Jun 15.

PMID:
26074012
23.

Predictors of chronic cerebrospinal venous insufficiency procedure use among older people with multiple sclerosis: a national case-control study.

Ploughman M, Manning OJ, Beaulieu S, Harris C, Hogan SH, Mayo N, Fisk JD, Sadovnick AD, O'Connor P, Morrow SA, Metz LM, Smyth P, Allderdice PW, Scott S, Marrie RA, Stefanelli M, Godwin M.

BMC Health Serv Res. 2015 Apr 16;15:161. doi: 10.1186/s12913-015-0835-y.

24.

The need for a disease-specific prospective pregnancy registry for multiple sclerosis (MS).

Alwan S, Chambers CD, Armenti VT, Sadovnick AD.

Mult Scler Relat Disord. 2015 Jan;4(1):6-17. doi: 10.1016/j.msard.2014.10.001. Epub 2014 Oct 24. Review.

PMID:
25787048
25.

Management of multiple sclerosis during pregnancy and the reproductive years: a systematic review.

Bove R, Alwan S, Friedman JM, Hellwig K, Houtchens M, Koren G, Lu E, McElrath TF, Smyth P, Tremlett H, Sadovnick AD.

Obstet Gynecol. 2014 Dec;124(6):1157-68. doi: 10.1097/AOG.0000000000000541. Review.

PMID:
25415167
26.

The Canadian survey of health, lifestyle and ageing with multiple sclerosis: methodology and initial results.

Ploughman M, Beaulieu S, Harris C, Hogan S, Manning OJ, Alderdice PW, Fisk JD, Sadovnick AD, O'Connor P, Morrow SA, Metz LM, Smyth P, Mayo N, Marrie RA, Knox KB, Stefanelli M, Godwin M.

BMJ Open. 2014 Jul 10;4(7):e005718. doi: 10.1136/bmjopen-2014-005718. Erratum in: BMJ Open. 2015;5(3):e005718.

27.

An assessment of genetic counseling services for individuals with multiple sclerosis.

Skinner S, Guimond C, Butler R, Dwosh E, Traboulsee AL, Sadovnick AD.

J Genet Couns. 2015 Feb;24(1):46-57. doi: 10.1007/s10897-014-9735-2. Epub 2014 Jul 5.

PMID:
24993688
28.

Genetic variants in IL2RA and IL7R affect multiple sclerosis disease risk and progression.

Traboulsee AL, Bernales CQ, Ross JP, Lee JD, Sadovnick AD, Vilariño-Güell C.

Neurogenetics. 2014 Aug;15(3):165-9. doi: 10.1007/s10048-014-0403-3. Epub 2014 Apr 26.

29.

Birth outcomes in newborns fathered by men with multiple sclerosis exposed to disease-modifying drugs.

Lu E, Zhu F, Zhao Y, van der Kop M, Synnes A, Dahlgren L, Sadovnick AD, Traboulsee A, Tremlett H.

CNS Drugs. 2014 May;28(5):475-82. doi: 10.1007/s40263-014-0154-6.

PMID:
24643915
30.

Birth outcomes of pregnancies fathered by men with multiple sclerosis.

Lu E, Zhu F, Zhao Y, van der Kop M, Sadovnick AD, Synnes A, Dahlgren L, Traboulsee A, Tremlett H.

Mult Scler. 2014 Aug;20(9):1260-4. doi: 10.1177/1352458514521308. Epub 2014 Feb 5.

PMID:
24500603
31.

Multiple sclerosis in the Iranian immigrant population of BC, Canada: prevalence and risk factors.

Guimond C, Lee JD, Ramagopalan SV, Dyment DA, Hanwell H, Giovannoni G, Criscuoli M, Yee IM, Vorobeychik G, Ebers GC, Sadovnick AD.

Mult Scler. 2014 Aug;20(9):1182-8. doi: 10.1177/1352458513519179. Epub 2014 Jan 10.

PMID:
24414537
32.

Progressive multiple sclerosis does not associate with rs996343 and rs2046748.

Bernales CQ, Ross JP, Lee JD, Zhao Y, Sadovnick AD, Traboulsee AL, Vilariño-Güell C.

Mult Scler. 2014 May;20(6):766-7. doi: 10.1177/1352458513517280. Epub 2013 Dec 24. No abstract available.

33.

A review of safety-related pregnancy data surrounding the oral disease-modifying drugs for multiple sclerosis.

Lu E, Wang BW, Alwan S, Synnes A, Dahlgren L, Sadovnick AD, Tremlett H.

CNS Drugs. 2014 Feb;28(2):89-94. doi: 10.1007/s40263-013-0131-5. Review.

PMID:
24343726
34.

Analysis of CYP27B1 in multiple sclerosis.

Ross JP, Bernales CQ, Lee JD, Sadovnick AD, Traboulsee AL, Vilariño-Güell C.

J Neuroimmunol. 2014 Jan 15;266(1-2):64-6. doi: 10.1016/j.jneuroim.2013.11.006. Epub 2013 Nov 23.

35.

Evaluation of late-onset Alzheimer disease genetic susceptibility risks in a Canadian population.

Omoumi A, Fok A, Greenwood T, Sadovnick AD, Feldman HH, Hsiung GY.

Neurobiol Aging. 2014 Apr;35(4):936.e5-12. doi: 10.1016/j.neurobiolaging.2013.09.025. Epub 2013 Oct 28.

PMID:
24176626
36.

Clinical and MRI activity as determinants of sample size for pediatric multiple sclerosis trials.

Verhey LH, Signori A, Arnold DL, Bar-Or A, Sadovnick AD, Marrie RA, Banwell B, Sormani MP.

Neurology. 2013 Oct 1;81(14):1215-21. doi: 10.1212/WNL.0b013e3182a6cb9b. Epub 2013 Aug 21.

37.

Colony stimulation factor 1 receptor (CSF1R) is not a common cause of multiple sclerosis.

Sadovnick AD, Traboulsee AL, Lee JD, Ross JP, Bernales CQ, Vilariño-Güell C.

Eur J Neurol. 2013 Sep;20(9):e115-6. doi: 10.1111/ene.12213. No abstract available.

38.

Obstetrical epidural and spinal anesthesia in multiple sclerosis.

Lu E, Zhao Y, Dahlgren L, Preston R, van der Kop M, Synnes A, Sadovnick AD, Traboulsee A, Tremlett H.

J Neurol. 2013 Oct;260(10):2620-8. doi: 10.1007/s00415-013-7035-7. Epub 2013 Jul 18.

PMID:
23864398
39.

Differential effects of genetic susceptibility factors in males and females with multiple sclerosis.

Sadovnick AD.

Clin Immunol. 2013 Nov;149(2):170-5. doi: 10.1016/j.clim.2013.05.002. Epub 2013 May 11. Review.

PMID:
23796437
40.

Multiple sclerosis and pregnancy: a comparison study.

Alwan S, Dybalski M, Yee IM, Greenwood TM, Roger E, Nadeau N, Duquette P, Sadovnick AD.

Can J Neurol Sci. 2013 Jul;40(4):590-6.

PMID:
23786746
41.

Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder.

Greenwood TA, Badner JA, Byerley W, Keck PE, McElroy SL, Remick RA, Sadovnick AD, Akiskal HS, Kelsoe JR.

J Affect Disord. 2013 Sep 25;150(3):1031-40. doi: 10.1016/j.jad.2013.05.035. Epub 2013 Jun 10.

42.

Variants in the promoter region of CYP7A1 are associated with neuromyelitis optica but not with multiple sclerosis in the Han Chinese population.

Zhao GX, Liu Y, Li ZX, Lv CZ, Traboulsee A, Sadovnick AD, Wu ZY.

Neurosci Bull. 2013 Oct;29(5):525-30. doi: 10.1007/s12264-013-1347-6. Epub 2013 Jun 5.

43.

TRPV1 gates tissue access and sustains pathogenicity in autoimmune encephalitis.

Paltser G, Liu XJ, Yantha J, Winer S, Tsui H, Wu P, Maezawa Y, Cahill LS, Laliberté CL, Ramagopalan SV, DeLuca GC, Sadovnick AD, Astsaturov I, Ebers GC, Henkelman RM, Salter MW, Dosch HM.

Mol Med. 2013 Jul 24;19:149-59. doi: 10.2119/molmed.2012.00329.

44.

Disease-modifying drugs for multiple sclerosis in pregnancy: a systematic review.

Charles JA, Tremlett H, Lu E, Guimond C, Sadovnick AD.

Neurology. 2013 Mar 12;80(11):1068-9. doi: 10.1212/01.wnl.0000428359.07207.f6. Review.

PMID:
23479468
45.

Association of smoking with risk of multiple sclerosis: a population-based study.

Ramagopalan SV, Lee JD, Yee IM, Guimond C, Traboulsee AL, Ebers GC, Sadovnick AD.

J Neurol. 2013 Jul;260(7):1778-81. doi: 10.1007/s00415-013-6873-7. Epub 2013 Mar 2.

PMID:
23455932
46.

Safety of disease-modifying drugs for multiple sclerosis in pregnancy: current challenges and future considerations for effective pharmacovigilance.

Lu E, Wang BW, Guimond C, Synnes A, Sadovnick AD, Dahlgren L, Traboulsee A, Tremlett H.

Expert Rev Neurother. 2013 Mar;13(3):251-60; quiz 261. doi: 10.1586/ern.13.12. Review.

PMID:
23448215
47.

The LRRK2 R1628P variant plays a protective role in Han Chinese population with Alzheimer's disease.

Li HL, Lu SJ, Sun YM, Guo QH, Sadovnick AD, Wu ZY.

CNS Neurosci Ther. 2013 Apr;19(4):207-15. doi: 10.1111/cns.12062. Epub 2013 Feb 20.

48.

Labor induction and augmentation in women with multiple sclerosis.

Lu E, Zhu F, van der Kop M, Dahlgren L, Synnes A, Sadovnick A, Traboulsee A, Tremlett H; British Columbia Multiple Sclerosis Clinic Neurologists.

Mult Scler. 2013 Aug;19(9):1182-9. doi: 10.1177/1352458512474090. Epub 2013 Feb 5.

PMID:
23386429
49.

Birth hospitalization in mothers with multiple sclerosis and their newborns.

Lu E, Zhao Y, Zhu F, van der Kop ML, Synnes A, Dahlgren L, Sadovnick AD, Sayao AL, Tremlett H; British Columbia Multiple Sclerosis Clinic Neurologists.

Neurology. 2013 Jan 29;80(5):447-52. doi: 10.1212/WNL.0b013e31827f0efc. Epub 2013 Jan 9.

50.

Association of dopamine transporter gene variants with childhood ADHD features in bipolar disorder.

Greenwood TA, Joo EJ, Shekhtman T, Sadovnick AD, Remick RA, Keck PE, McElroy SL, Kelsoe JR.

Am J Med Genet B Neuropsychiatr Genet. 2013 Mar;162B(2):137-45. doi: 10.1002/ajmg.b.32108. Epub 2012 Dec 19.

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