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Items: 45

1.

Pro-resolving lipid mediators: Agents of anti-ageing?

Doyle R, Sadlier DM, Godson C.

Semin Immunol. 2018 Dec;40:36-48. doi: 10.1016/j.smim.2018.09.002. Epub 2018 Oct 4. Review.

PMID:
30293857
2.

Renal transplantation outcomes following heart and heart-lung transplantation.

Wong L, Chee YR, Healy DG, Egan JJ, Sadlier DM, O'Meara YM.

Ir J Med Sci. 2017 Nov;186(4):1027-1032. doi: 10.1007/s11845-016-1550-3. Epub 2016 Dec 31.

PMID:
28040832
3.

The effect of obesity on acute kidney injury after cardiac surgery.

O'Sullivan KE, Byrne JS, Hudson A, Murphy AM, Sadlier DM, Hurley JP.

J Thorac Cardiovasc Surg. 2015 Dec;150(6):1622-8. doi: 10.1016/j.jtcvs.2015.08.082. Epub 2015 Sep 26.

4.

Genetic Evidence for a Causal Role of Obesity in Diabetic Kidney Disease.

Todd JN, Dahlström EH, Salem RM, Sandholm N, Forsblom C; FinnDiane Study Group, McKnight AJ, Maxwell AP, Brennan E, Sadlier D, Godson C, Groop PH, Hirschhorn JN, Florez JC.

Diabetes. 2015 Dec;64(12):4238-46. doi: 10.2337/db15-0254. Epub 2015 Aug 25.

5.

The effect of bariatric surgery on renal function and disease: a focus on outcomes and inflammation.

Neff KJ, Frankel AH, Tam FW, Sadlier DM, Godson C, le Roux CW.

Nephrol Dial Transplant. 2013 Nov;28 Suppl 4:iv73-82. doi: 10.1093/ndt/gft262. Epub 2013 Sep 26. Review.

PMID:
24071659
6.

Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes.

Sandholm N, McKnight AJ, Salem RM, Brennan EP, Forsblom C, Harjutsalo V, Mäkinen VP, McKay GJ, Sadlier DM, Williams WW, Martin F, Panduru NM, Tarnow L, Tuomilehto J, Tryggvason K, Zerbini G, Comeau ME, Langefeld CD; FIND Consortium, Godson C, Hirschhorn JN, Maxwell AP, Florez JC, Groop PH; FinnDiane Study Group and the GENIE Consortium.

J Am Soc Nephrol. 2013 Oct;24(10):1537-43. doi: 10.1681/ASN.2012111122. Epub 2013 Sep 12.

7.

Lipoxins attenuate renal fibrosis by inducing let-7c and suppressing TGFβR1.

Brennan EP, Nolan KA, Börgeson E, Gough OS, McEvoy CM, Docherty NG, Higgins DF, Murphy M, Sadlier DM, Ali-Shah ST, Guiry PJ, Savage DA, Maxwell AP, Martin F, Godson C; GENIE Consortium.

J Am Soc Nephrol. 2013 Mar;24(4):627-37. doi: 10.1681/ASN.2012060550. Epub 2013 Mar 21.

8.

The genetics of diabetic nephropathy.

Brennan E, McEvoy C, Sadlier D, Godson C, Martin F.

Genes (Basel). 2013 Nov 5;4(4):596-619. doi: 10.3390/genes4040596.

9.

New susceptibility loci associated with kidney disease in type 1 diabetes.

Sandholm N, Salem RM, McKnight AJ, Brennan EP, Forsblom C, Isakova T, McKay GJ, Williams WW, Sadlier DM, Mäkinen VP, Swan EJ, Palmer C, Boright AP, Ahlqvist E, Deshmukh HA, Keller BJ, Huang H, Ahola AJ, Fagerholm E, Gordin D, Harjutsalo V, He B, Heikkilä O, Hietala K, Kytö J, Lahermo P, Lehto M, Lithovius R, Osterholm AM, Parkkonen M, Pitkäniemi J, Rosengård-Bärlund M, Saraheimo M, Sarti C, Söderlund J, Soro-Paavonen A, Syreeni A, Thorn LM, Tikkanen H, Tolonen N, Tryggvason K, Tuomilehto J, Wadén J, Gill GV, Prior S, Guiducci C, Mirel DB, Taylor A, Hosseini SM; DCCT/EDIC Research Group, Parving HH, Rossing P, Tarnow L, Ladenvall C, Alhenc-Gelas F, Lefebvre P, Rigalleau V, Roussel R, Tregouet DA, Maestroni A, Maestroni S, Falhammar H, Gu T, Möllsten A, Cimponeriu D, Ioana M, Mota M, Mota E, Serafinceanu C, Stavarachi M, Hanson RL, Nelson RG, Kretzler M, Colhoun HM, Panduru NM, Gu HF, Brismar K, Zerbini G, Hadjadj S, Marre M, Groop L, Lajer M, Bull SB, Waggott D, Paterson AD, Savage DA, Bain SC, Martin F, Hirschhorn JN, Godson C, Florez JC, Groop PH, Maxwell AP.

PLoS Genet. 2012 Sep;8(9):e1002921. doi: 10.1371/journal.pgen.1002921. Epub 2012 Sep 20.

10.

Association testing of previously reported variants in a large case-control meta-analysis of diabetic nephropathy.

Williams WW, Salem RM, McKnight AJ, Sandholm N, Forsblom C, Taylor A, Guiducci C, McAteer JB, McKay GJ, Isakova T, Brennan EP, Sadlier DM, Palmer C, Söderlund J, Fagerholm E, Harjutsalo V, Lithovius R, Gordin D, Hietala K, Kytö J, Parkkonen M, Rosengård-Bärlund M, Thorn L, Syreeni A, Tolonen N, Saraheimo M, Wadén J, Pitkäniemi J, Sarti C, Tuomilehto J, Tryggvason K, Österholm AM, He B, Bain S, Martin F, Godson C, Hirschhorn JN, Maxwell AP, Groop PH, Florez JC; GENIE Consortium.

Diabetes. 2012 Aug;61(8):2187-94. Epub 2012 Jun 20.

11.

Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathy.

Brennan EP, Morine MJ, Walsh DW, Roxburgh SA, Lindenmeyer MT, Brazil DP, Gaora PÓ, Roche HM, Sadlier DM, Cohen CD; GENIE Consortium, Godson C, Martin F.

Biochim Biophys Acta. 2012 Apr;1822(4):589-99. doi: 10.1016/j.bbadis.2012.01.008. Epub 2012 Jan 14.

12.

A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome.

Francis NJ, McNicholas B, Awan A, Waldron M, Reddan D, Sadlier D, Kavanagh D, Strain L, Marchbank KJ, Harris CL, Goodship TH.

Blood. 2012 Jan 12;119(2):591-601. doi: 10.1182/blood-2011-03-339903. Epub 2011 Nov 4.

13.

A functional and transcriptomic analysis of NET1 bioactivity in gastric cancer.

Bennett G, Sadlier D, Doran PP, Macmathuna P, Murray DW.

BMC Cancer. 2011 Feb 1;11:50. doi: 10.1186/1471-2407-11-50.

14.

CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: implications for the pathogenesis of diabetic nephropathy.

Rooney B, O'Donovan H, Gaffney A, Browne M, Faherty N, Curran SP, Sadlier D, Godson C, Brazil DP, Crean J.

FEBS Lett. 2011 Feb 4;585(3):531-8. doi: 10.1016/j.febslet.2011.01.004. Epub 2011 Jan 14.

15.

Genetic polymorphisms in nitric oxide synthase 3 gene and implications for kidney disease: a meta-analysis.

McKnight AJ, Patterson CC, Sandholm N, Kilner J, Buckham TA, Parkkonen M, Forsblom C, Sadlier DM, Groop PH, Maxwell AP; Warren 3/UK GoKinD Study Group.

Am J Nephrol. 2010;32(5):476-81. doi: 10.1159/000321340. Epub 2010 Oct 20.

PMID:
20962522
16.

Investigation of ACE, ACE2 and AGTR1 genes for association with nephropathy in Type 1 diabetes mellitus.

Currie D, McKnight AJ, Patterson CC, Sadlier DM, Maxwell AP; UK Warren 3/GoKinD Study Group.

Diabet Med. 2010 Oct;27(10):1188-94. doi: 10.1111/j.1464-5491.2010.03097.x.

PMID:
20854388
17.

Early viral and peripheral blood mononuclear cell responses to pegylated interferon and ribavirin treatment: the first 24 h.

Devitt E, Lawless MW, Sadlier D, Browne JA, Walsh C, Crowe J.

Eur J Gastroenterol Hepatol. 2010 Oct;22(10):1211-20. doi: 10.1097/MEG.0b013e32833caf7b.

PMID:
20631625
18.

Investigation of the association of BMP gene variants with nephropathy in Type 1 diabetes mellitus.

McKnight AJ, Pettigrew KA, Patterson CC, Kilner J, Sadlier DM, Maxwell AP; Warren 3/UK GoKinD Study Group.

Diabet Med. 2010 Jun;27(6):624-30. doi: 10.1111/j.1464-5491.2010.02976.x.

PMID:
20546278
19.

DNA methylation profiling in cell models of diabetic nephropathy.

Brennan EP, Ehrich M, O'Donovan H, Brazil DP, Crean JK, Murphy M, Sadlier DM, Martin F, Godson C, van den Boom D, Maxwell AP, Savage DA.

Epigenetics. 2010 Jul 1;5(5):396-401. Epub 2010 Jul 1.

PMID:
20458172
20.

Resequencing of the CCL5 and CCR5 genes and investigation of variants for association with diabetic nephropathy.

Pettigrew KA, McKnight AJ, Patterson CC, Kilner J, Sadlier DM, Maxwell AP.

J Hum Genet. 2010 Apr;55(4):248-51. doi: 10.1038/jhg.2010.15. Epub 2010 Mar 5.

PMID:
20203694
21.

A GREM1 gene variant associates with diabetic nephropathy.

McKnight AJ, Patterson CC, Pettigrew KA, Savage DA, Kilner J, Murphy M, Sadlier D, Maxwell AP; Warren 3/U.K. Genetics of Kidneys in Diabetes (GoKinD) Study Group.

J Am Soc Nephrol. 2010 May;21(5):773-81. doi: 10.1681/ASN.2009070773. Epub 2010 Feb 11.

22.

A rare haplotype of the vitamin D receptor gene is protective against diabetic nephropathy.

Martin RJ, McKnight AJ, Patterson CC, Sadlier DM, Maxwell AP; Warren 3/UK GoKinD Study Group.

Nephrol Dial Transplant. 2010 Feb;25(2):497-503. doi: 10.1093/ndt/gfp515. Epub 2009 Sep 27.

PMID:
19783860
23.

Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer.

Doherty GA, Byrne SM, Austin SC, Scully GM, Sadlier DM, Neilan TG, Kay EW, Murray FE, Fitzgerald DJ.

Br J Cancer. 2009 Aug 4;101(3):483-91. doi: 10.1038/sj.bjc.6605144.

24.

Comparative analysis of DNA methylation profiles in peripheral blood leukocytes versus lymphoblastoid cell lines.

Brennan EP, Ehrich M, Brazil DP, Crean JK, Murphy M, Sadlier DM, Martin F, Godson C, McKnight AJ, van den Boom D, Maxwell AP, Savage DA.

Epigenetics. 2009 Apr 1;4(3):159-64. Epub 2009 Apr 18.

PMID:
19440041
25.

Genetic analysis of coronary artery disease single-nucleotide polymorphisms in diabetic nephropathy.

McKnight AJ, Maxwell AP, Fogarty DG, Sadlier D, Savage DA; Warren 3/UK GoKinD Study Group.

Nephrol Dial Transplant. 2009 Aug;24(8):2473-6. doi: 10.1093/ndt/gfp015. Epub 2009 Mar 31.

PMID:
19336575
26.

Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies.

Gallego-Delgado J, Connolly SB, Lázaro A, Sadlier D, Kieran NE, Sugrue DD, Doran P, Brady HR, Osende J, Egido J.

Hypertens Res. 2009 May;32(5):347-57. doi: 10.1038/hr.2009.27. Epub 2009 Mar 27.

PMID:
19325563
27.

Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus.

McKnight AJ, Woodman AM, Parkkonen M, Patterson CC, Savage DA, Forsblom C, Pettigrew KA, Sadlier D, Groop PH, Maxwell AP; Warren 3/UK GoKinD Study Group.

Diabetologia. 2009 May;52(5):844-9. doi: 10.1007/s00125-009-1281-3. Epub 2009 Feb 27.

PMID:
19247629
28.

Investigation of Adducin 2 (beta) DNA polymorphisms in genetic predisposition to diabetic nephropathy in Type 1 diabetes.

Currie D, Maxwell AP, Sadlier D, McKnight AJ; Warren 3/UK GoKinD Study Group.

Diabet Med. 2008 Aug;25(8):1001-5. doi: 10.1111/j.1464-5491.2008.02511.x.

PMID:
18959617
29.

No support for association of protein kinase C, beta 1 (PRKCB1) gene promoter polymorphisms c.-1504C>T and c.-546C>G with diabetic nephropathy in Type 1 diabetes.

Pettigrew KA, McKnight AJ, Martin RJ, Patterson CC, Kilner J, Sadlier D, Maxwell AP, Savage DA; Warren 3/UK GoKinD Study Group.

Diabet Med. 2008 Sep;25(9):1127-9. doi: 10.1111/j.1464-5491.2008.02540.x. No abstract available.

PMID:
18937679
30.

Lung tissue storage: optimizing conditions for future use in molecular research.

Keating DT, Malizia AP, Sadlier D, Hurson C, Wood AE, McCarthy J, Nolke L, Egan JJ, Doran PP.

Exp Lung Res. 2008 Oct;34(8):455-66. doi: 10.1080/01902140802093162.

PMID:
18850373
31.

Regulation and consequences of differential gene expression in diabetic kidney disease.

Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, Godson C.

Biochem Soc Trans. 2008 Oct;36(Pt 5):941-5. doi: 10.1042/BST0360941.

PMID:
18793165
32.

Genetic association analyses of non-synonymous single nucleotide polymorphisms in diabetic nephropathy.

Savage DA, Patterson CC, Deloukas P, Whittaker P, McKnight AJ, Morrison J, Boulton AJ, Demaine AG, Marshall SM, Millward BA, Thomas SM, Viberti GC, Walker JD, Sadlier D, Maxwell AP, Bain SC.

Diabetologia. 2008 Nov;51(11):1998-2002. doi: 10.1007/s00125-008-1142-5. Epub 2008 Sep 5.

33.
35.

Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis.

Hurson CJ, Butler JS, Keating DT, Murray DW, Sadlier DM, O'Byrne JM, Doran PP.

BMC Musculoskelet Disord. 2007 Feb 12;8:12.

36.

Microarray identifies ADAM family members as key responders to TGF-beta1 in alveolar epithelial cells.

Keating DT, Sadlier DM, Patricelli A, Smith SM, Walls D, Egan JJ, Doran PP.

Respir Res. 2006 Sep 1;7:114.

37.

Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis.

Sadlier DM, Ouyang X, McMahon B, Mu W, Ohashi R, Rodgers K, Murray D, Nakagawa T, Godson C, Doran P, Brady HR, Johnson RJ.

Kidney Int. 2005 Dec;68(6):2542-61.

38.

Lipoxin A4 modifies platelet-derived growth factor-induced pro-fibrotic gene expression in human renal mesangial cells.

Rodgers K, McMahon B, Mitchell D, Sadlier D, Godson C.

Am J Pathol. 2005 Sep;167(3):683-94.

39.

Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy.

Dolan V, Murphy M, Sadlier D, Lappin D, Doran P, Godson C, Martin F, O'Meara Y, Schmid H, Henger A, Kretzler M, Droguett A, Mezzano S, Brady HR.

Am J Kidney Dis. 2005 Jun;45(6):1034-9.

PMID:
15957132
40.

Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy.

Sadlier DM, Connolly SB, Kieran NE, Roxburgh S, Brazil DP, Kairaitis L, Wang Y, Harris DC, Doran P, Brady HR.

J Biol Chem. 2004 Jul 9;279(28):29670-80. Epub 2004 Mar 18.

41.

Transcriptome profiling and the pathogenesis of diabetic complications.

Connolly SB, Sadlier D, Kieran NE, Doran P, Brady HR.

J Am Soc Nephrol. 2003 Aug;14(8 Suppl 3):S279-83. Review.

42.

Impact evaluation of an oral health intervention amongst primary school children in Ireland.

Friel S, Hope A, Kelleher C, Comer S, Sadlier D.

Health Promot Int. 2002 Jun;17(2):119-26.

PMID:
11986293
43.

Smoking habits and attitudes of Irish dentists and dental students.

McCartan BE, Sadlier D, O'Mullane DM.

J Ir Dent Assoc. 1993;39(2):26-9.

PMID:
8301160
44.

The Kilkenny Integrated Oral Health Project.

Daly B, Hobdell MH, Sadlier D, Jennings N.

Ir J Med Sci. 1991 Jan;160 Suppl 9:50-4.

PMID:
1938324
45.

ABO blood group and social class: a prospective study in a regional blood bank.

Kelleher C, Cooper J, Sadlier D.

J Epidemiol Community Health. 1990 Mar;44(1):59-61.

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