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Items: 19


A Probe-Enabled Approach for the Selective Isolation and Characterization of Functionally Active Subpopulations in the Gut Microbiome.

Whidbey C, Sadler NC, Nair RN, Volk RF, DeLeon AJ, Bramer LM, Fansler SJ, Hansen JR, Shukla AK, Jansson JK, Thrall BD, Wright AT.

J Am Chem Soc. 2019 Jan 9;141(1):42-47. doi: 10.1021/jacs.8b09668. Epub 2018 Dec 17.


Multifunctional Activity-Based Protein Profiling of the Developing Lung.

Stoddard EG, Volk RF, Carson JP, Ljungberg CM, Murphree TA, Smith JN, Sadler NC, Shukla AK, Ansong C, Wright AT.

J Proteome Res. 2018 Aug 3;17(8):2623-2634. doi: 10.1021/acs.jproteome.8b00086. Epub 2018 Jul 18.


High-Fat Diets Alter the Modulatory Effects of Xenobiotics on Cytochrome P450 Activities.

Sadler NC, Webb-Robertson BM, Clauss TR, Pounds JG, Corley R, Wright AT.

Chem Res Toxicol. 2018 May 21;31(5):308-318. doi: 10.1021/acs.chemrestox.8b00008. Epub 2018 May 4.


Activity-Based Probes for Isoenzyme- and Site-Specific Functional Characterization of Glutathione S-Transferases.

Stoddard EG, Killinger BJ, Nair RN, Sadler NC, Volk RF, Purvine SO, Shukla AK, Smith JN, Wright AT.

J Am Chem Soc. 2017 Nov 15;139(45):16032-16035. doi: 10.1021/jacs.7b07378. Epub 2017 Nov 1.


Indirect Interspecies Regulation: Transcriptional and Physiological Responses of a Cyanobacterium to Heterotrophic Partnership.

Bernstein HC, McClure RS, Thiel V, Sadler NC, Kim YM, Chrisler WB, Hill EA, Bryant DA, Romine MF, Jansson JK, Fredrickson JK, Beliaev AS.

mSystems. 2017 Mar 7;2(2). pii: e00181-16. doi: 10.1128/mSystems.00181-16. eCollection 2017 Mar-Apr.


Dinitrogenase-Driven Photobiological Hydrogen Production Combats Oxidative Stress in Cyanothece sp. Strain ATCC 51142.

Sadler NC, Bernstein HC, Melnicki MR, Charania MA, Hill EA, Anderson LN, Monroe ME, Smith RD, Beliaev AS, Wright AT.

Appl Environ Microbiol. 2016 Nov 21;82(24):7227-7235. Print 2016 Dec 15.


Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development.

Sadler NC, Nandhikonda P, Webb-Robertson BJ, Ansong C, Anderson LN, Smith JN, Corley RA, Wright AT.

Drug Metab Dispos. 2016 Jul;44(7):984-91. doi: 10.1124/dmd.115.068593. Epub 2016 Apr 15.


Systematic Survey of Serine Hydrolase Activity in Mycobacterium tuberculosis Defines Changes Associated with Persistence.

Ortega C, Anderson LN, Frando A, Sadler NC, Brown RW, Smith RD, Wright AT, Grundner C.

Cell Chem Biol. 2016 Feb 18;23(2):290-298. doi: 10.1016/j.chembiol.2016.01.003. Epub 2016 Feb 4.


Activity-Based Protein Profiling of Ammonia Monooxygenase in Nitrosomonas europaea.

Bennett K, Sadler NC, Wright AT, Yeager C, Hyman MR.

Appl Environ Microbiol. 2016 Apr 4;82(8):2270-2279. doi: 10.1128/AEM.03556-15. Print 2016 Apr.


Role of Cytochrome P450 Hydroxylase in the Decreased Accumulation of Vitamin E in Muscle from Turkeys Compared to that from Chickens.

Perez DM, Richards MP, Parker RS, Berres ME, Wright AT, Sifri M, Sadler NC, Tatiyaborworntham N, Li N.

J Agric Food Chem. 2016 Jan 27;64(3):671-80. doi: 10.1021/acs.jafc.5b05433. Epub 2016 Jan 12.


Multi-Omic Dynamics Associate Oxygenic Photosynthesis with Nitrogenase-Mediated H2 Production in Cyanothece sp. ATCC 51142.

Bernstein HC, Charania MA, McClure RS, Sadler NC, Melnicki MR, Hill EA, Markillie LM, Nicora CD, Wright AT, Romine MF, Beliaev AS.

Sci Rep. 2015 Nov 3;5:16004. doi: 10.1038/srep16004.


Advancing understanding of microbial bioenergy conversion processes by activity-based protein profiling.

Liu Y, Fredrickson JK, Sadler NC, Nandhikonda P, Smith RD, Wright AT.

Biotechnol Biofuels. 2015 Sep 25;8:156. doi: 10.1186/s13068-015-0343-7. eCollection 2015. Review.


Activity-based protein profiling of microbes.

Sadler NC, Wright AT.

Curr Opin Chem Biol. 2015 Feb;24:139-44. doi: 10.1016/j.cbpa.2014.10.022. Epub 2014 Dec 19. Review.


Characterization of protein redox dynamics induced during light-to-dark transitions and nutrient limitation in cyanobacteria.

Ansong C, Sadler NC, Hill EA, Lewis MP, Zink EM, Smith RD, Beliaev AS, Konopka AE, Wright AT.

Front Microbiol. 2014 Jul 3;5:325. doi: 10.3389/fmicb.2014.00325. eCollection 2014.


Organelle-specific activity-based protein profiling in living cells.

Wiedner SD, Anderson LN, Sadler NC, Chrisler WB, Kodali VK, Smith RD, Wright AT.

Angew Chem Int Ed Engl. 2014 Mar 10;53(11):2919-22. doi: 10.1002/anie.201309135. Epub 2014 Feb 6.


Deficient expression of aldehyde dehydrogenase 1A1 is consistent with increased sensitivity of Gorlin syndrome patients to radiation carcinogenesis.

Wright AT, Magnaldo T, Sontag RL, Anderson LN, Sadler NC, Piehowski PD, Gache Y, Weber TJ.

Mol Carcinog. 2015 Jun;54(6):473-84. doi: 10.1002/mc.22115. Epub 2013 Nov 27.


Live cell chemical profiling of temporal redox dynamics in a photoautotrophic cyanobacterium.

Sadler NC, Melnicki MR, Serres MH, Merkley ED, Chrisler WB, Hill EA, Romine MF, Kim S, Zink EM, Datta S, Smith RD, Beliaev AS, Konopka A, Wright AT.

ACS Chem Biol. 2014 Jan 17;9(1):291-300. doi: 10.1021/cb400769v. Epub 2013 Nov 6.


Impact of pregnancy on the pharmacokinetics of dibenzo[def,p]chrysene in mice.

Crowell SR, Sharma AK, Amin S, Soelberg JJ, Sadler NC, Wright AT, Baird WM, Williams DE, Corley RA.

Toxicol Sci. 2013 Sep;135(1):48-62. doi: 10.1093/toxsci/kft124. Epub 2013 Jun 6.


Activity-based protein profiling reveals mitochondrial oxidative enzyme impairment and restoration in diet-induced obese mice.

Sadler NC, Angel TE, Lewis MP, Pederson LM, Chauvigné-Hines LM, Wiedner SD, Zink EM, Smith RD, Wright AT.

PLoS One. 2012;7(10):e47996. doi: 10.1371/journal.pone.0047996. Epub 2012 Oct 24.

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