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Items: 1 to 50 of 56

1.

A Case of SF3B1-Positive Myelodysplastic/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis

Lazo-Langner A, Sadikovic B.

Turk J Haematol. 2019 Feb 7;36(1):48-49. doi: 10.4274/tjh.galenos.2018.2018.0267. Epub 2018 Nov 23. No abstract available.

2.

BAFopathies' DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin-Siris and Nicolaides-Baraitser syndromes.

Aref-Eshghi E, Bend EG, Hood RL, Schenkel LC, Carere DA, Chakrabarti R, Nagamani SCS, Cheung SW, Campeau PM, Prasad C, Siu VM, Brady L, Tarnopolsky MA, Callen DJ, Innes AM, White SM, Meschino WS, Shuen AY, Paré G, Bulman DE, Ainsworth PJ, Lin H, Rodenhiser DI, Hennekam RC, Boycott KM, Schwartz CE, Sadikovic B.

Nat Commun. 2018 Nov 20;9(1):4885. doi: 10.1038/s41467-018-07193-y.

3.

The ClinGen Epilepsy Gene Curation Expert Panel-Bridging the divide between clinical domain knowledge and formal gene curation criteria.

Helbig I, Riggs ER, Barry CA, Klein KM, Dyment D, Thaxton C, Sadikovic B, Sands TT, Wagnon JL, Liaquat K, Cilio MR, Mirzaa G, Park K, Axeen E, Butler E, Bardakjian TM, Striano P, Poduri A, Siegert RK, Grant AR, Helbig KL, Mefford HC.

Hum Mutat. 2018 Nov;39(11):1476-1484. doi: 10.1002/humu.23632.

PMID:
30311377
4.

Hypogammaglobulinemia and imaging features in a patient with infantile free sialic acid storage disease (ISSD) and a novel mutation in the SLC17A5 gene.

Žigman T, Petković Ramadža D, Lušić M, Zekušić M, Ninković D, Gardijan D, Potočki K, Omerza L, Beljan L, Žarković K, Kerkhof J, Ljubojević M, de Sain-van der Velden M, Vuković J, Fumić K, Sadiković B, Barić I.

J Pediatr Endocrinol Metab. 2018 Oct 25;31(10):1155-1159. doi: 10.1515/jpem-2017-0397.

PMID:
30243016
5.

Endothelin-1 regulation is entangled in a complex web of epigenetic mechanisms in diabetes.

Biswas S, Feng B, Thomas A, Chen S, Aref-Eshghi E, Sadikovic B, Chakrabarti S.

Physiol Res. 2018 Jun 27;67(Supplementum 1):S115-S125.

6.

Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues.

Aref-Eshghi E, Schenkel LC, Ainsworth P, Lin H, Rodenhiser DI, Cutz JC, Sadikovic B.

Front Oncol. 2018 Apr 23;8:100. doi: 10.3389/fonc.2018.00100. eCollection 2018.

7.

MALAT1: An Epigenetic Regulator of Inflammation in Diabetic Retinopathy.

Biswas S, Thomas AA, Chen S, Aref-Eshghi E, Feng B, Gonder J, Sadikovic B, Chakrabarti S.

Sci Rep. 2018 Apr 25;8(1):6526. doi: 10.1038/s41598-018-24907-w.

8.

CPEO - Like mitochondrial myopathy associated with m.8340G>A mutation.

Tarnopolsky MA, Sundaram ANE, Provias J, Brady L, Sadikovic B.

Mitochondrion. 2018 Mar 6. pii: S1567-7249(17)30331-8. doi: 10.1016/j.mito.2018.02.008. [Epub ahead of print]

PMID:
29501485
9.

Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C.

Schenkel LC, Aref-Eshghi E, Skinner C, Ainsworth P, Lin H, Paré G, Rodenhiser DI, Schwartz C, Sadikovic B.

Clin Epigenetics. 2018 Feb 14;10:21. doi: 10.1186/s13148-018-0453-8. eCollection 2018.

10.

Complete elimination of a pathogenic homoplasmic mtDNA mutation in one generation.

Brady L, Sadikovic B, Rupar CA, Tarnopolsky MA.

Mitochondrion. 2018 Feb 1. pii: S1567-7249(17)30328-8. doi: 10.1016/j.mito.2018.01.010. [Epub ahead of print]

PMID:
29408632
11.

Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes.

Aref-Eshghi E, Rodenhiser DI, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Hood RL, Bulman DE, Kernohan KD; Care4Rare Canada Consortium, Boycott KM, Campeau PM, Schwartz C, Sadikovic B.

Am J Hum Genet. 2018 Jan 4;102(1):156-174. doi: 10.1016/j.ajhg.2017.12.008.

12.

Correction: Sequence Homology at the Breakpoint and Clinical Phenotype of Mitochondrial DNA Deletion Syndromes.

Sadikovic B, Wang J, El-Hattab AW, Landsverk M, Douglas G, Brundage EK, Craigen WJ, Schmitt ES, Wong LC.

PLoS One. 2017 Nov 20;12(11):e0188610. doi: 10.1371/journal.pone.0188610. eCollection 2017.

13.

The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance.

Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Rodenhiser D, Schwartz C, Sadikovic B.

Epigenetics. 2017;12(11):923-933. doi: 10.1080/15592294.2017.1381807. Epub 2017 Nov 7.

14.

Clinical Validation of Copy Number Variant Detection from Targeted Next-Generation Sequencing Panels.

Kerkhof J, Schenkel LC, Reilly J, McRobbie S, Aref-Eshghi E, Stuart A, Rupar CA, Adams P, Hegele RA, Lin H, Rodenhiser D, Knoll J, Ainsworth PJ, Sadikovic B.

J Mol Diagn. 2017 Nov;19(6):905-920. doi: 10.1016/j.jmoldx.2017.07.004. Epub 2017 Aug 15.

PMID:
28818680
15.

Clinical Validation of a Genome-Wide DNA Methylation Assay for Molecular Diagnosis of Imprinting Disorders.

Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Siu V, Rodenhiser D, Schwartz C, Sadikovic B.

J Mol Diagn. 2017 Nov;19(6):848-856. doi: 10.1016/j.jmoldx.2017.07.002. Epub 2017 Aug 12.

PMID:
28807811
16.

An aggressive multifocal primary CNS histiocytosis with PTPN11 (Shp2) mutation.

Zhang Q, Shibani A, Sadikovic B, Howlett CJ, Ang LC.

Neuropathol Appl Neurobiol. 2018 Feb;44(2):240-243. doi: 10.1111/nan.12404. No abstract available.

PMID:
28403515
17.

Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome.

Schenkel LC, Kernohan KD, McBride A, Reina D, Hodge A, Ainsworth PJ, Rodenhiser DI, Pare G, Bérubé NG, Skinner C, Boycott KM, Schwartz C, Sadikovic B.

Epigenetics Chromatin. 2017 Mar 10;10:10. doi: 10.1186/s13072-017-0118-4. eCollection 2017.

18.

Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors.

Schenkel LC, Rodenhiser D, Siu V, McCready E, Ainsworth P, Sadikovic B.

J Pediatr Genet. 2017 Mar;6(1):30-41. doi: 10.1055/s-0036-1593849. Epub 2016 Nov 8. Review.

19.

The defining DNA methylation signature of Floating-Harbor Syndrome.

Hood RL, Schenkel LC, Nikkel SM, Ainsworth PJ, Pare G, Boycott KM, Bulman DE, Sadikovic B.

Sci Rep. 2016 Dec 9;6:38803. doi: 10.1038/srep38803.

20.

Movement Disorders Associated With Hemochromatosis.

Kumar N, Rizek P, Sadikovic B, Adams PC, Jog M.

Can J Neurol Sci. 2016 Nov;43(6):801-808.

PMID:
27827297
21.

Clinical Validation of Fragile X Syndrome Screening by DNA Methylation Array.

Schenkel LC, Schwartz C, Skinner C, Rodenhiser DI, Ainsworth PJ, Pare G, Sadikovic B.

J Mol Diagn. 2016 Nov;18(6):834-841. doi: 10.1016/j.jmoldx.2016.06.005. Epub 2016 Aug 29.

PMID:
27585064
22.

Clinical evaluation of a hemochromatosis next-generation sequencing gene panel.

Lanktree MB, Sadikovic B, Waye JS, Levstik A, Lanktree BB, Yudin J, Crowther MA, Pare G, Adams PC.

Eur J Haematol. 2017 Mar;98(3):228-234. doi: 10.1111/ejh.12820. Epub 2016 Nov 11.

PMID:
27753142
23.

Identification of a methylation profile for DNMT1-associated autosomal dominant cerebellar ataxia, deafness, and narcolepsy.

Kernohan KD, Cigana Schenkel L, Huang L, Smith A, Pare G, Ainsworth P; Care4Rare Canada Consortium, Boycott KM, Warman-Chardon J, Sadikovic B.

Clin Epigenetics. 2016 Sep 5;8:91. doi: 10.1186/s13148-016-0254-x. eCollection 2016.

24.

Clinical Next-Generation Sequencing Pipeline Outperforms a Combined Approach Using Sanger Sequencing and Multiplex Ligation-Dependent Probe Amplification in Targeted Gene Panel Analysis.

Schenkel LC, Kerkhof J, Stuart A, Reilly J, Eng B, Woodside C, Levstik A, Howlett CJ, Rupar AC, Knoll JHM, Ainsworth P, Waye JS, Sadikovic B.

J Mol Diagn. 2016 Sep;18(5):657-667. doi: 10.1016/j.jmoldx.2016.04.002. Epub 2016 Jul 2.

PMID:
27376475
25.

DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome.

Schenkel LC, Rodenhiser DI, Ainsworth PJ, Paré G, Sadikovic B.

Crit Rev Clin Lab Sci. 2016;53(3):147-65. doi: 10.3109/10408363.2015.1113496. Epub 2016 Jan 12. Review.

PMID:
26758403
26.

Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia.

Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G, Sadikovic B.

Eur J Haematol. 2016 Apr;96(4):360-6. doi: 10.1111/ejh.12597. Epub 2015 Jul 3.

PMID:
26059983
27.

The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical Geneticists.

Boycott K, Hartley T, Adam S, Bernier F, Chong K, Fernandez BA, Friedman JM, Geraghty MT, Hume S, Knoppers BM, Laberge AM, Majewski J, Mendoza-Londono R, Meyn MS, Michaud JL, Nelson TN, Richer J, Sadikovic B, Skidmore DL, Stockley T, Taylor S, van Karnebeek C, Zawati MH, Lauzon J, Armour CM; Canadian College of Medical Geneticists.

J Med Genet. 2015 Jul;52(7):431-7. doi: 10.1136/jmedgenet-2015-103144. Epub 2015 May 7.

28.

Examining the clinical use of hemochromatosis genetic testing.

Lanktree MB, Lanktree BB, Paré G, Waye JS, Sadikovic B, Crowther MA.

Can J Gastroenterol Hepatol. 2015 Jan-Feb;29(1):41-5.

29.

A 42-year-old man with elevated ferritin.

Lanktree MB, Sadikovic B, Crowther MA.

CMAJ. 2015 Aug 11;187(11):820-1. doi: 10.1503/cmaj.140259. Epub 2014 Oct 6. Review. No abstract available.

30.

Prader-Willi syndrome and Tay-Sachs disease in association with mixed maternal uniparental isodisomy and heterodisomy 15 in a girl who also had isochromosome Xq.

Zeesman S, McCready E, Sadikovic B, Nowaczyk MJ.

Am J Med Genet A. 2015 Jan;167A(1):180-4. doi: 10.1002/ajmg.a.36790. Epub 2014 Oct 6.

PMID:
25287655
31.

Mutation Update for UBE3A variants in Angelman syndrome.

Sadikovic B, Fernandes P, Zhang VW, Ward PA, Miloslavskaya I, Rhead W, Rosenbaum R, Gin R, Roa B, Fang P.

Hum Mutat. 2014 Dec;35(12):1407-17. doi: 10.1002/humu.22687.

PMID:
25212744
32.

Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer.

Bell K, Hodgson N, Levine M, Sadikovic B, Zbuk K.

Breast Cancer Res Treat. 2014 Jul;146(2):447-50. doi: 10.1007/s10549-014-3011-x. Epub 2014 Jun 12.

PMID:
24916180
33.

Genomics and epigenomics in pediatric oncology and clinical laboratory genetics.

Sadikovic B, Pare G.

Clin Biochem. 2014 Jun;47(9):731-2. doi: 10.1016/j.clinbiochem.2014.05.033. Epub 2014 May 20. No abstract available.

PMID:
24858242
34.

Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis?

Cervigne NK, Machado J, Goswami RS, Sadikovic B, Bradley G, Perez-Ordonez B, Galloni NN, Gilbert R, Gullane P, Irish JC, Jurisica I, Reis PP, Kamel-Reid S.

Hum Mol Genet. 2014 May 15;23(10):2618-28. doi: 10.1093/hmg/ddt657. Epub 2014 Jan 8.

35.

NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation.

Mahadevan S, Wen S, Wan YW, Peng HH, Otta S, Liu Z, Iacovino M, Mahen EM, Kyba M, Sadikovic B, Van den Veyver IB.

Hum Mol Genet. 2014 Feb 1;23(3):706-16. doi: 10.1093/hmg/ddt457. Epub 2013 Sep 18.

36.

Array comparative genomic hybridization in osteosarcoma.

Sadikovic B, Park PC, Selvarajah S, Zielenska M.

Methods Mol Biol. 2013;973:227-47. doi: 10.1007/978-1-62703-281-0_15. Review.

PMID:
23412794
37.

A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism.

Celestino-Soper PB, Violante S, Crawford EL, Luo R, Lionel AC, Delaby E, Cai G, Sadikovic B, Lee K, Lo C, Gao K, Person RE, Moss TJ, German JR, Huang N, Shinawi M, Treadwell-Deering D, Szatmari P, Roberts W, Fernandez B, Schroer RJ, Stevenson RE, Buxbaum JD, Betancur C, Scherer SW, Sanders SJ, Geschwind DH, Sutcliffe JS, Hurles ME, Wanders RJ, Shaw CA, Leal SM, Cook EH Jr, Goin-Kochel RP, Vaz FM, Beaudet AL.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):7974-81. doi: 10.1073/pnas.1120210109. Epub 2012 May 7.

38.

Chronic maternal protein deprivation in mice is associated with overexpression of the cohesin-mediator complex in liver of their offspring.

Balasa A, Sanchez-Valle A, Sadikovic B, Sangi-Haghpeykar H, Bravo J, Chen L, Liu W, Wen S, Fiorotto ML, Veyver IB.

J Nutr. 2011 Dec;141(12):2106-12. doi: 10.3945/jn.111.146597. Epub 2011 Oct 19.

39.

Sequence homology at the breakpoint and clinical phenotype of mitochondrial DNA deletion syndromes.

Sadikovic B, Wang J, El-Hattab AW, Landsverk M, Douglas G, Brundage EK, Craigen WJ, Schmitt ES, Wong LJ.

PLoS One. 2010 Dec 20;5(12):e15687. doi: 10.1371/journal.pone.0015687. Erratum in: PLoS One. 2017 Nov 20;12 (11):e0188610.

40.

Immunohistochemical expression and cluster analysis of mesenchymal and neural stem cell-associated proteins in pediatric soft tissue sarcomas.

Sadikovic B, Graham C, Ho M, Zielenska M, Somers GR.

Pediatr Dev Pathol. 2011 Jul-Aug;14(4):259-72. doi: 10.2350/10-08-0890-OA.1. Epub 2010 Dec 16.

PMID:
21162641
41.

Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy.

Sadikovic B, Thorner P, Chilton-Macneill S, Martin JW, Cervigne NK, Squire J, Zielenska M.

BMC Cancer. 2010 May 13;10:202. doi: 10.1186/1471-2407-10-202.

42.

Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma.

Cervigne NK, Reis PP, Machado J, Sadikovic B, Bradley G, Galloni NN, Pintilie M, Jurisica I, Perez-Ordonez B, Gilbert R, Gullane P, Irish J, Kamel-Reid S.

Hum Mol Genet. 2009 Dec 15;18(24):4818-29. doi: 10.1093/hmg/ddp446. Epub 2009 Sep 23.

PMID:
19776030
43.

Cause and consequences of genetic and epigenetic alterations in human cancer.

Sadikovic B, Al-Romaih K, Squire JA, Zielenska M.

Curr Genomics. 2008 Sep;9(6):394-408. doi: 10.2174/138920208785699580.

44.

Identification of interactive networks of gene expression associated with osteosarcoma oncogenesis by integrated molecular profiling.

Sadikovic B, Yoshimoto M, Chilton-MacNeill S, Thorner P, Squire JA, Zielenska M.

Hum Mol Genet. 2009 Jun 1;18(11):1962-75. doi: 10.1093/hmg/ddp117. Epub 2009 Mar 13.

PMID:
19286668
45.

Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays.

Kron K, Pethe V, Briollais L, Sadikovic B, Ozcelik H, Sunderji A, Venkateswaran V, Pinthus J, Fleshner N, van der Kwast T, Bapat B.

PLoS One. 2009;4(3):e4830. doi: 10.1371/journal.pone.0004830. Epub 2009 Mar 13.

46.

In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma.

Sadikovic B, Yoshimoto M, Al-Romaih K, Maire G, Zielenska M, Squire JA.

PLoS One. 2008 Jul 30;3(7):e2834. doi: 10.1371/journal.pone.0002834.

47.

Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays.

Rodenhiser DI, Andrews J, Kennette W, Sadikovic B, Mendlowitz A, Tuck AB, Chambers AF.

Breast Cancer Res. 2008;10(4):R62. doi: 10.1186/bcr2121. Epub 2008 Jul 18.

48.

Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells.

Al-Romaih K, Sadikovic B, Yoshimoto M, Wang Y, Zielenska M, Squire JA.

Neoplasia. 2008 May;10(5):471-80.

49.

Genome-wide H3K9 histone acetylation profiles are altered in benzopyrene-treated MCF7 breast cancer cells.

Sadikovic B, Andrews J, Carter D, Robinson J, Rodenhiser DI.

J Biol Chem. 2008 Feb 15;283(7):4051-60. Epub 2007 Dec 7.

50.

DNA methylation analysis using CpG microarrays is impaired in benzopyrene exposed cells.

Sadikovic B, Andrews J, Rodenhiser DI.

Toxicol Appl Pharmacol. 2007 Dec 15;225(3):300-9. Epub 2007 Aug 23.

PMID:
17904174

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