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Items: 1 to 50 of 53

1.

Association of insulin growth factor-1 and growth hormone levels in elderly renal transplant recipients with cardiac dysfunction.

Soliman AR, Soliman MA, Sadek KM.

Saudi J Kidney Dis Transpl. 2019 Jan-Feb;30(1):62-67.

PMID:
30804268
2.

The possible neuroprotective effects of melatonin in aluminum chloride-induced neurotoxicity via antioxidant pathway and Nrf2 signaling apart from metal chelation.

Sadek KM, Lebda MA, Abouzed TK.

Environ Sci Pollut Res Int. 2019 Feb 4. doi: 10.1007/s11356-019-04430-9. [Epub ahead of print]

PMID:
30719664
3.

Aroyl and acyl cyanides as orthogonal protecting groups or as building blocks for the synthesis of heterocycles.

Sadek KU, Mekheimer RA, Abd-Elmonem M, Elnagdi MH.

Mol Divers. 2019 Jan 21. doi: 10.1007/s11030-019-09915-w. [Epub ahead of print] Review.

PMID:
30666490
4.

Papaya extract upregulates the immune and antioxidants-related genes, and proteins expression in milk somatic cells of Friesian dairy cows.

Abouzed TK, Sadek KM, Ayoub MM, Saleh EA, Nasr SM, El-Sayed YS, Shoukry M.

J Anim Physiol Anim Nutr (Berl). 2019 Mar;103(2):407-415. doi: 10.1111/jpn.13032. Epub 2018 Dec 3.

PMID:
30511402
5.

Water-pipe smoking promotes epithelial-mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways.

Sadek KW, Haik MY, Ashour AA, Baloch T, Aboulkassim T, Yasmeen A, Vranic S, Zeidan A, Al Moustafa AE.

Cancer Cell Int. 2018 Nov 13;18:180. doi: 10.1186/s12935-018-0678-9. eCollection 2018.

6.

Effect of Reducing Medication Regimen Complexity on Glycaemic Control in Patients with Diabetes.

Abdelaziz TS, Sadek KM.

Rom J Intern Med. 2018 Oct 4. pii: /j/rjim.ahead-of-print/rjim-2018-0029/rjim-2018-0029.xml. doi: 10.2478/rjim-2018-0029. [Epub ahead of print]

PMID:
30375357
7.

Serum β-glucuronidase activity as a biomarker for acute cholinesterase inhibitor pesticide poisoning.

Beltagy DM, Sadek KM, Hafez AS.

Toxicol Ind Health. 2018 Oct 23:748233718802068. doi: 10.1177/0748233718802068. [Epub ahead of print]

PMID:
30352546
8.

Potential role of α-lipoic acid and Ginkgo biloba against silver nanoparticles-induced neuronal apoptosis and blood-brain barrier impairments in rats.

Lebda MA, Sadek KM, Tohamy HG, Abouzed TK, Shukry M, Umezawa M, El-Sayed YS.

Life Sci. 2018 Nov 1;212:251-260. doi: 10.1016/j.lfs.2018.10.011. Epub 2018 Oct 7.

PMID:
30304694
9.

The molecular and biochemical insight view of lycopene in ameliorating tramadol-induced liver toxicity in a rat model: implication of oxidative stress, apoptosis, and MAPK signaling pathways.

Sadek KM, Lebda MA, Abouzed TK, Nasr SM, El-Sayed Y.

Environ Sci Pollut Res Int. 2018 Nov;25(33):33119-33130. doi: 10.1007/s11356-018-3265-7. Epub 2018 Sep 24.

PMID:
30251044
10.

Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling.

Takeuchi Y, Kito A, Itoh S, Naruse H, Fujikawa J, Sadek KM, Akiyama S, Yamashiro T, Wakisaka S, Abe M.

Exp Cell Res. 2018 Oct 15;371(2):417-425. doi: 10.1016/j.yexcr.2018.09.002. Epub 2018 Sep 5.

PMID:
30193838
11.

Role of lncRNAs as prognostic markers of hepatic cancer and potential therapeutic targeting by S-adenosylmethionine via inhibiting PI3K/Akt signaling pathways.

Sadek KM, Lebda MA, Nasr NE, Nasr SM, El-Sayed Y.

Environ Sci Pollut Res Int. 2018 Jul;25(20):20057-20070. doi: 10.1007/s11356-018-2179-8. Epub 2018 May 10.

PMID:
29748795
12.

Red onion scales ameliorated streptozotocin-induced diabetes and diabetic nephropathy in Wistar rats in relation to their metabolite fingerprint.

Abouzed TK, Contreras MDM, Sadek KM, Shukry M, H Abdelhady D, Gouda WM, Abdo W, Nasr NE, Mekky RH, Segura-Carretero A, Kahilo KA, Abdel-Sattar E.

Diabetes Res Clin Pract. 2018 Jun;140:253-264. doi: 10.1016/j.diabres.2018.03.042. Epub 2018 Apr 5.

PMID:
29626589
13.

Retraction: Role and potential targeting of hepatic apurinic/apyrimidinic endonuclease-1 and cyclin-dependent kinase-4 in hepatocellular carcinoma.

Sadek K, Abouzed T, Nasr S, Shoukry M.

Can J Physiol Pharmacol. 2018 Mar;96(3):317. doi: 10.1139/cjpp-2018-0071. No abstract available.

PMID:
29493318
14.

Molecular hepatoprotective effects of lipoic acid against carbon tetrachloride-induced liver fibrosis in rats: Hepatoprotection at molecular level.

Sadek KM, Saleh EA, Nasr SM.

Hum Exp Toxicol. 2018 Feb;37(2):142-154. doi: 10.1177/0960327117693066. Epub 2017 Feb 21.

PMID:
29233029
15.

Melatonin mitigates thioacetamide-induced hepatic fibrosis via antioxidant activity and modulation of proinflammatory cytokines and fibrogenic genes.

Lebda MA, Sadek KM, Abouzed TK, Tohamy HG, El-Sayed YS.

Life Sci. 2018 Jan 1;192:136-143. doi: 10.1016/j.lfs.2017.11.036. Epub 2017 Nov 24.

PMID:
29180002
16.

Spectrum of kidney diseases in patients presented for acute hemodialysis in Kasr Al-Aini School of Medicine.

Sadek KM, Zayed BM, Eldeeb MM, Ahmed DH, Aly AA, Belal DM.

Saudi J Kidney Dis Transpl. 2017 Jul-Aug;28(4):860-868.

17.

Neuro- and nephrotoxicity of subchronic cadmium chloride exposure and the potential chemoprotective effects of selenium nanoparticles.

Sadek KM, Lebda MA, Abouzed TK, Nasr SM, Shoukry M.

Metab Brain Dis. 2017 Oct;32(5):1659-1673. doi: 10.1007/s11011-017-0053-x. Epub 2017 Jun 28.

PMID:
28660360
18.

Aspartame and Soft Drink-Mediated Neurotoxicity in Rats: Implication of Oxidative Stress, Apoptotic Signaling Pathways, Electrolytes and Hormonal Levels.

Lebda MA, Sadek KM, El-Sayed YS.

Metab Brain Dis. 2017 Oct;32(5):1639-1647. doi: 10.1007/s11011-017-0052-y. Epub 2017 Jun 28.

PMID:
28660358
19.

Macrophage Migration Inhibitory Factor (MIF) Gene Promotor Polymorphism Is Associated with Increased Fibrosis in Biliary Atresia Patients, but Not with Disease Susceptibility.

Sadek KH, Ezzat S, Abdel-Aziz SA, Alaraby H, Mosbeh A, Abdel-Rahman MH.

Ann Hum Genet. 2017 Sep;81(5):177-183. doi: 10.1111/ahg.12199. Epub 2017 Jun 28.

PMID:
28657145
20.

Spirulina platensis prevents hyperglycemia in rats by modulating gluconeogenesis and apoptosis via modification of oxidative stress and MAPK-pathways.

Sadek KM, Lebda MA, Nasr SM, Shoukry M.

Biomed Pharmacother. 2017 Aug;92:1085-1094. doi: 10.1016/j.biopha.2017.06.023. Epub 2017 Jun 12.

PMID:
28622709
21.

Substantial Toxic Effect of Water-Pipe Smoking on the Early Stage of Embryonic Development.

Ashour AA, Haik MY, Sadek KW, Yalcin HC, Bitharas J, Aboulkassim T, Batist G, Yasmeen A, Al Moustafa AE.

Nicotine Tob Res. 2018 Mar 6;20(4):502-507. doi: 10.1093/ntr/ntx135.

PMID:
28605482
22.

The chemo-prophylactic efficacy of an ethanol Moringa oleifera leaf extract against hepatocellular carcinoma in rats.

Sadek KM, Abouzed TK, Abouelkhair R, Nasr S.

Pharm Biol. 2017 Dec;55(1):1458-1466. doi: 10.1080/13880209.2017.1306713.

23.

Selective, reliable blood and milk bio-markers for diagnosing clinical and subclinical bovine mastitis.

Sadek K, Saleh E, Ayoub M.

Trop Anim Health Prod. 2017 Feb;49(2):431-437. doi: 10.1007/s11250-016-1190-7. Epub 2016 Dec 3.

PMID:
27915437
24.

Camel milk and bee honey regulate profibrotic cytokine gene transcripts in liver cirrhosis induced by carbon tetrachloride.

Sadek K, Beltagy D, Saleh E, Abouelkhair R.

Can J Physiol Pharmacol. 2016 Nov;94(11):1141-1150. doi: 10.1139/cjpp-2015-0596. Epub 2016 May 30.

PMID:
27455095
25.

Lycopene modulates cholinergic dysfunction, Bcl-2/Bax balance, and antioxidant enzymes gene transcripts in monosodium glutamate (E621) induced neurotoxicity in a rat model.

Sadek K, Abouzed T, Nasr S.

Can J Physiol Pharmacol. 2016 Apr;94(4):394-401. doi: 10.1139/cjpp-2015-0388. Epub 2015 Nov 19.

PMID:
26900785
26.

Effect of Genetic Polymorphisms in GH/Hpa II and MSTN / Dra I Loci on Body Weight in Friesian Bull Calves.

Nasr SM, Ateya AI, Sadek KM, Radwan HA.

Pak J Biol Sci. 2016;19(8-9):338-344. doi: 10.3923/pjbs.2016.338.344.

PMID:
29023020
27.

An algorithm to improve diagnostic accuracy in diabetes in computerised problem orientated medical records (POMR) compared with an established algorithm developed in episode orientated records (EOMR).

de Lusignan S, Liaw ST, Dedman D, Khunti K, Sadek K, Jones S.

J Innov Health Inform. 2015 Jun 5;22(2):255-64. doi: 10.14236/jhi.v22i2.79.

28.

Synthesis and Characterization of New 1,2,4-Triazolo[1,5-a]pyridines That Extend the Life Span of Caenorhabiditis elegans via Their Anti-Inflammatory/Antioxidant Effects.

Mekheimer RA, Sayed AA, Ahmed EA, Sadek KU.

Arch Pharm (Weinheim). 2015 Sep;348(9):650-65. doi: 10.1002/ardp.201500069. Epub 2015 Jun 18.

PMID:
26088545
29.

Synthesis, reactivity, and biological activity of 5-aminouracil and its derivatives.

Shaker RM, Abd Elrady M, Sadek KU.

Mol Divers. 2016 Feb;20(1):153-83. doi: 10.1007/s11030-015-9595-1. Epub 2015 Apr 30. Review.

PMID:
25926388
30.

Recent developments in utility of green multi-component reactions for the efficient synthesis of polysubstituted pyrans, thiopyrans, pyridines, and pyrazoles.

Elnagdi MH, Moustafa MS, Al-Mousawi SM, Mekheimer RA, Sadek KU.

Mol Divers. 2015 Aug;19(3):625-51. doi: 10.1007/s11030-015-9594-2. Epub 2015 Apr 17. Review.

PMID:
25894364
31.

Diet-induced maternal obesity alters ovarian morphology and gene expression in the adult mouse offspring.

Cheong Y, Sadek KH, Bruce KD, Macklon N, Cagampang FR.

Fertil Steril. 2014 Sep;102(3):899-907. doi: 10.1016/j.fertnstert.2014.06.015. Epub 2014 Jul 22.

PMID:
25063726
32.

Fasting ameliorates metabolism, immunity, and oxidative stress in carbon tetrachloride-intoxicated rats.

Sadek K, Saleh E.

Hum Exp Toxicol. 2014 Dec;33(12):1277-83. doi: 10.1177/0960327114527629. Epub 2014 Mar 20.

PMID:
24651824
33.

Synthesis and spectroscopic properties of new azo dyes derived from 3-ethylthio-5-cyanomethyl-4-phenyl-1,2,4-triazole.

Al-Sheikh M, Medrasi HY, Sadek KU, Mekheimer RA.

Molecules. 2014 Mar 7;19(3):2993-3003. doi: 10.3390/molecules19032993.

34.

Should women with chronic pelvic pain have adhesiolysis?

Cheong YC, Reading I, Bailey S, Sadek K, Ledger W, Li TC.

BMC Womens Health. 2014 Mar 4;14(1):36. doi: 10.1186/1472-6874-14-36.

35.

Diabetes screening after gestational diabetes in England: a quantitative retrospective cohort study.

McGovern A, Butler L, Jones S, van Vlymen J, Sadek K, Munro N, Carr H, de Lusignan S.

Br J Gen Pract. 2014 Jan;64(618):e17-23. doi: 10.3399/bjgp14X676410.

36.

One for the road! A study to assess the efficacy of single low-dose regimen of rasburicase in controlling hyperuricaemia in patients with tumour lysis syndrome due to haematological malignancies.

Azim HA, Bahr SA, Kamal NS, Koura MA, Tolba R, Gad HA, Morsy A, Attia HM, Iskander I, Hammad A, Hemed MF, Abdallah MF, Sadek KA, Taha AH.

Ecancermedicalscience. 2013 Dec 10;7:378. doi: 10.3332/ecancer.2013.378. eCollection 2013.

37.

Biochemical efficacy of vitamin D in ameliorating endocrine and metabolic disorders in diabetic rats.

Sadek KM, Shaheen H.

Pharm Biol. 2014 May;52(5):591-6. doi: 10.3109/13880209.2013.854812. Epub 2013 Nov 20.

PMID:
24251869
38.

Chemotherapeutic efficacy of an ethanolic Moringa oleifera leaf extract against chromium-induced testicular toxicity in rats.

Sadek KM.

Andrologia. 2014;46(9):1047-54. doi: 10.1111/and.12196. Epub 2013 Nov 12.

PMID:
24215114
39.

Acute Transverse Myelitis Associated with Buserelin Use during IVF.

Alleemudder DI, Sadek K, Fountain S, Davies S.

Case Rep Obstet Gynecol. 2013;2013:386765. doi: 10.1155/2013/386765. Epub 2013 Mar 28.

40.

Poor sleep in PCOS; is melatonin the culprit?

Shreeve N, Cagampang F, Sadek K, Tolhurst M, Houldey A, Hill CM, Brook N, Macklon N, Cheong Y.

Hum Reprod. 2013 May;28(5):1348-53. doi: 10.1093/humrep/det013. Epub 2013 Feb 24.

PMID:
23438443
41.

Variation in stability of housekeeping genes in healthy and adhesion-related mesothelium.

Sadek KH, Cagampang FR, Bruce KD, Macklon N, Cheong Y.

Fertil Steril. 2012 Oct;98(4):1023-7. doi: 10.1016/j.fertnstert.2012.06.033. Epub 2012 Jul 13.

PMID:
22795637
42.

Green and highly efficient synthesis of 2-arylbenzothiazoles using glycerol without catalyst at ambient temperature.

Sadek KU, Mekheimer RA, Hameed AM, Elnahas F, Elnagdi MH.

Molecules. 2012 May 18;17(5):6011-9. doi: 10.3390/molecules17056011.

43.

Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating.

Sadek KU, Mekheimer RA, Mohamed TM, Moustafa MS, Elnagdi MH.

Beilstein J Org Chem. 2012;8:18-24. doi: 10.3762/bjoc.8.3. Epub 2012 Jan 4.

44.
45.

Call for consistent coding in diabetes mellitus using the Royal College of General Practitioners and NHS pragmatic classification of diabetes.

de Lusignan S, Sadek K, McDonald H, Horsfield P, Sadek NH, Tahir A, Desombre T, Khunti K.

Inform Prim Care. 2012;20(2):103-13.

46.

Intralipid therapy for recurrent implantation failure: new hope or false dawn?

Shreeve N, Sadek K.

J Reprod Immunol. 2012 Jan;93(1):38-40. doi: 10.1016/j.jri.2011.11.003. Epub 2011 Dec 21.

PMID:
22196107
47.

Case Study in Refractory Non-Hodgkin's Lymphoma: Successful Treatment with Plerixafor.

Azim HA, Bahr SA, Koura MA, Gad H, Farouk M, Morsy A, Iskander I, Hammad A, Fat'hy M, Attia H, Sadek K.

Case Rep Oncol. 2011 Sep;4(3):467-9. doi: 10.1159/000331663. Epub 2011 Sep 17.

48.

Variation in stability of housekeeping genes in endometrium of healthy and polycystic ovarian syndrome women.

Sadek KH, Cagampang FR, Bruce KD, Shreeve N, Macklon N, Cheong Y.

Hum Reprod. 2012 Jan;27(1):251-6. doi: 10.1093/humrep/der363. Epub 2011 Nov 3.

PMID:
22052386
49.

Adhesion reduction agents in gynaecological procedures: can NHS aff ord it? An economic cost efficiency analysis.

Cheong Y, Sadek K, Watson A, Metwally M, Li TC.

J Obstet Gynaecol. 2011 Oct;31(7):631-5. doi: 10.3109/01443615.2011.590912.

PMID:
21973138
50.

Hypothesis: Role for the circadian Clock system and sleep in the pathogenesis of adhesions and chronic pelvic pain?

Sadek K, Macklon N, Bruce K, Cagampang F, Cheong Y.

Med Hypotheses. 2011 Mar;76(3):453-6. doi: 10.1016/j.mehy.2010.11.020. Epub 2010 Dec 13.

PMID:
21146320

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