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Items: 49

1.

Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis.

Rotter D, Peiris H, Grinsfelder DB, Martin AM, Burchfield J, Parra V, Hull C, Morales CR, Jessup CF, Matusica D, Parks BW, Lusis AJ, Nguyen NUN, Oh M, Iyoke I, Jakkampudi T, McMillan DR, Sadek HA, Watt MJ, Gupta RK, Pritchard MA, Keating DJ, Rothermel BA.

EMBO Rep. 2018 Nov 2. pii: e44706. doi: 10.15252/embr.201744706. [Epub ahead of print]

PMID:
30389725
2.

The Effect of Hypoxia on Cardiovascular Disease: Friend or Foe?

Savla JJ, Levine BD, Sadek HA.

High Alt Med Biol. 2018 Jun;19(2):124-130. doi: 10.1089/ham.2018.0044.

PMID:
29939783
3.

Meis1 Regulates Postnatal Cardiomyocyte Cell Cycle Arrest.

Muralidhar SA, Sadek HA.

In: Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, editors. Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet]. Tokyo: Springer; 2016. Chapter 11.
2016 Jun 25.

4.

Hypoxia promotes primitive glycosaminoglycan-rich extracellular matrix composition in developing heart valves.

Amofa D, Hulin A, Nakada Y, Sadek HA, Yutzey KE.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1143-H1154. doi: 10.1152/ajpheart.00209.2017. Epub 2017 Aug 25.

PMID:
28842437
5.

Hypoxia-induced myocardial regeneration.

Kimura W, Nakada Y, Sadek HA.

J Appl Physiol (1985). 2017 Dec 1;123(6):1676-1681. doi: 10.1152/japplphysiol.00328.2017. Epub 2017 Aug 17.

PMID:
28819000
6.

Cardiomyocyte renewal in the human heart: insights from the fall-out.

Lázár E, Sadek HA, Bergmann O.

Eur Heart J. 2017 Aug 7;38(30):2333-2342. doi: 10.1093/eurheartj/ehx343. Review.

7.

Cardiomyocyte Regeneration: A Consensus Statement.

Eschenhagen T, Bolli R, Braun T, Field LJ, Fleischmann BK, Frisén J, Giacca M, Hare JM, Houser S, Lee RT, Marbán E, Martin JF, Molkentin JD, Murry CE, Riley PR, Ruiz-Lozano P, Sadek HA, Sussman MA, Hill JA.

Circulation. 2017 Aug 15;136(7):680-686. doi: 10.1161/CIRCULATIONAHA.117.029343. Epub 2017 Jul 6. Review. No abstract available.

8.

Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association.

Hill JA, Ardehali R, Clarke KT, Del Zoppo GJ, Eckhardt LL, Griendling KK, Libby P, Roden DM, Sadek HA, Seidman CE, Vaughan DE; American Heart Association Council on Basic Cardiovascular Sciences; Council on Clinical Cardiology; Council on Epidemiology and Prevention; Council on Functional Genomics and Translational Biology; and Stroke Council.

Circ Res. 2017 Jul 21;121(3):e2-e8. doi: 10.1161/RES.0000000000000155. Epub 2017 Jun 26. Review.

PMID:
28652256
9.

Redox Regulation of Heart Regeneration: An Evolutionary Tradeoff.

Elhelaly WM, Lam NT, Hamza M, Xia S, Sadek HA.

Front Cell Dev Biol. 2016 Dec 15;4:137. doi: 10.3389/fcell.2016.00137. eCollection 2016.

10.

Inflammation-Induced Oxidative Stress Mediates Gene Fusion Formation in Prostate Cancer.

Mani RS, Amin MA, Li X, Kalyana-Sundaram S, Veeneman BA, Wang L, Ghosh A, Aslam A, Ramanand SG, Rabquer BJ, Kimura W, Tran M, Cao X, Roychowdhury S, Dhanasekaran SM, Palanisamy N, Sadek HA, Kapur P, Koch AE, Chinnaiyan AM.

Cell Rep. 2016 Dec 6;17(10):2620-2631. doi: 10.1016/j.celrep.2016.11.019.

11.

Hypoxia induces heart regeneration in adult mice.

Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Hu Z, Deberardinis RJ, Schiattarella G, Hill JA, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA.

Nature. 2017 Jan 12;541(7636):222-227. doi: 10.1038/nature20173. Epub 2016 Oct 31.

PMID:
27798600
12.

The relationship between the BMI and the emotional status of Alexandria University students, Egypt.

Abdel Sadek HA, Abu-Nazel MW, Shata ZN, Abd El-Fatah NK.

J Egypt Public Health Assoc. 2016 Sep;91(3):101-108.

PMID:
27749640
13.

Corrigendum: Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart.

Kimura W, Xiao F, Canseco DC, Muralidhar S, Thet S, Zhang HM, Abderrahman Y, Chen R, Garcia JA, Shelton JM, Richardson JA, Ashour AM, Asaithamby A, Liang H, Xing C, Lu Z, Cheng Zhang C, Sadek HA.

Nature. 2016 Apr 14;532(7598):268. doi: 10.1038/nature16177. Epub 2015 Dec 23. No abstract available.

PMID:
26700813
14.

Hypoxic metabolism in human hematopoietic stem cells.

Kocabas F, Xie L, Xie J, Yu Z, DeBerardinis RJ, Kimura W, Thet S, Elshamy AF, Abouellail H, Muralidhar S, Liu X, Chen C, Sadek HA, Zhang CC, Zheng J.

Cell Biosci. 2015 Jul 17;5:39. doi: 10.1186/s13578-015-0020-3. eCollection 2015.

15.

Defining the Limit of Embryonic Heart Regeneration.

Nakada Y, Kimura W, Sadek HA.

Circulation. 2015 Jul 14;132(2):77-8. doi: 10.1161/CIRCULATIONAHA.115.017070. No abstract available.

PMID:
26169647
16.

Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart.

Kimura W, Xiao F, Canseco DC, Muralidhar S, Thet S, Zhang HM, Abderrahman Y, Chen R, Garcia JA, Shelton JM, Richardson JA, Ashour AM, Asaithamby A, Liang H, Xing C, Lu Z, Zhang CC, Sadek HA.

Nature. 2015 Jul 9;523(7559):226-30. doi: 10.1038/nature14582. Epub 2015 Jun 22. Erratum in: Nature. 2016 Apr 14;532(7598):268.

PMID:
26098368
17.

Neonatal heart regeneration: mounting support and need for technical standards.

Sen S, Sadek HA.

J Am Heart Assoc. 2015 Jan 27;4(1):e001727. doi: 10.1161/JAHA.114.001727. No abstract available.

18.

Human ventricular unloading induces cardiomyocyte proliferation.

Canseco DC, Kimura W, Garg S, Mukherjee S, Bhattacharya S, Abdisalaam S, Das S, Asaithamby A, Mammen PP, Sadek HA.

J Am Coll Cardiol. 2015 Mar 10;65(9):892-900. doi: 10.1016/j.jacc.2014.12.027. Epub 2015 Jan 21.

19.

A hippo "AKT" regulates cardiomyocyte proliferation.

Xiao F, Kimura W, Sadek HA.

Circ Res. 2015 Jan 2;116(1):3-5. doi: 10.1161/CIRCRESAHA.114.305325. No abstract available.

20.

Multi-investigator letter on reproducibility of neonatal heart regeneration following apical resection.

Sadek HA, Martin JF, Takeuchi JK, Leor J, Nie Y, Giacca M, Lee RT.

Stem Cell Reports. 2014 Jul 8;3(1):1. doi: 10.1016/j.stemcr.2014.06.009. eCollection 2014 Jul 8. No abstract available. Erratum in: Stem Cell Reports. 2014 Oct 14;3(4):690. Nei, Yu [corrected to Nie, Yu].

21.

Metabolic characterization of hematopoietic stem cells.

Kocabas F, Zheng J, Zhang C, Sadek HA.

Methods Mol Biol. 2014;1185:155-64. doi: 10.1007/978-1-4939-1133-2_10.

PMID:
25062627
22.

Redox signaling in cardiac renewal.

Kimura W, Muralidhar S, Canseco DC, Puente B, Zhang CC, Xiao F, Abderrahman YH, Sadek HA.

Antioxid Redox Signal. 2014 Oct 10;21(11):1660-73. doi: 10.1089/ars.2014.6029. Epub 2014 Sep 5. Review.

23.

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.

Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA.

Cell. 2014 Apr 24;157(3):565-79. doi: 10.1016/j.cell.2014.03.032. Erratum in: Cell. 2014 May 22;157(5):1243.

24.

Cardiomyocyte cell cycle: Meis-ing something?

Mahmoud AI, Canseco D, Xiao F, Sadek HA.

Cell Cycle. 2014;13(7):1057-8. doi: 10.4161/cc.28379. Epub 2014 Feb 27. No abstract available.

25.

Macrophages are required for neonatal heart regeneration.

Aurora AB, Porrello ER, Tan W, Mahmoud AI, Hill JA, Bassel-Duby R, Sadek HA, Olson EN.

J Clin Invest. 2014 Mar;124(3):1382-92. doi: 10.1172/JCI72181. Epub 2014 Feb 24.

26.

Surgical models for cardiac regeneration in neonatal mice.

Mahmoud AI, Porrello ER, Kimura W, Olson EN, Sadek HA.

Nat Protoc. 2014 Feb;9(2):305-11. doi: 10.1038/nprot.2014.021. Epub 2014 Jan 16.

27.

The cardiac hypoxic niche: emerging role of hypoxic microenvironment in cardiac progenitors.

Kimura W, Sadek HA.

Cardiovasc Diagn Ther. 2012 Dec;2(4):278-89. doi: 10.3978/j.issn.2223-3652.2012.12.02. Review.

28.

Hippo pathway effector Yap promotes cardiac regeneration.

Xin M, Kim Y, Sutherland LB, Murakami M, Qi X, McAnally J, Porrello ER, Mahmoud AI, Tan W, Shelton JM, Richardson JA, Sadek HA, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13839-44. doi: 10.1073/pnas.1313192110. Epub 2013 Aug 5.

29.

Hypoxia and metabolic properties of hematopoietic stem cells.

Zhang CC, Sadek HA.

Antioxid Redox Signal. 2014 Apr 20;20(12):1891-901. doi: 10.1089/ars.2012.5019. Epub 2013 Jun 21. Review.

30.

Meis1 regulates postnatal cardiomyocyte cell cycle arrest.

Mahmoud AI, Kocabas F, Muralidhar SA, Kimura W, Koura AS, Thet S, Porrello ER, Sadek HA.

Nature. 2013 May 9;497(7448):249-253. doi: 10.1038/nature12054. Epub 2013 Apr 17.

31.

Harnessing the power of dividing cardiomyocytes.

Muralidhar SA, Mahmoud AI, Canseco D, Xiao F, Sadek HA.

Glob Cardiol Sci Pract. 2013 Nov 1;2013(3):212-21. doi: 10.5339/gcsp.2013.29. eCollection 2013. Review.

32.

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.

Porrello ER, Mahmoud AI, Simpson E, Johnson BA, Grinsfelder D, Canseco D, Mammen PP, Rothermel BA, Olson EN, Sadek HA.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):187-92. doi: 10.1073/pnas.1208863110. Epub 2012 Dec 17.

33.

The relationship between associative learning, transfer generalization, and homocysteine levels in mild cognitive impairment.

Moustafa AA, Hewedi DH, Eissa AM, Myers CE, Sadek HA.

PLoS One. 2012;7(9):e46496. doi: 10.1371/journal.pone.0046496. Epub 2012 Sep 28.

34.

Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells.

Kocabas F, Zheng J, Thet S, Copeland NG, Jenkins NA, DeBerardinis RJ, Zhang C, Sadek HA.

Blood. 2012 Dec 13;120(25):4963-72. doi: 10.1182/blood-2012-05-432260. Epub 2012 Sep 20.

35.

The hypoxic epicardial and subepicardial microenvironment.

Kocabas F, Mahmoud AI, Sosic D, Porrello ER, Chen R, Garcia JA, DeBerardinis RJ, Sadek HA.

J Cardiovasc Transl Res. 2012 Oct;5(5):654-65. Epub 2012 May 8. Erratum in: J Cardiovasc Transl Res. 2012 Oct;5(5):666.

PMID:
22566269
36.

MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca²⁺ overload and cell death.

Aurora AB, Mahmoud AI, Luo X, Johnson BA, van Rooij E, Matsuzaki S, Humphries KM, Hill JA, Bassel-Duby R, Sadek HA, Olson EN.

J Clin Invest. 2012 Apr;122(4):1222-32. doi: 10.1172/JCI59327. Epub 2012 Mar 19.

37.

Quantitative assessment of Wilms tumor 1 (WT1) gene transcripts in Egyptian acute lymphoblastic leukemia patients.

Sadek HA, El-Metnawey WH, Shaheen IA, Korshied MM, Mohamed AS.

J Investig Med. 2011 Dec;59(8):1258-62. doi: 10.2130/JIM.0b013e31822a24f7.

PMID:
21804407
38.

Transient regenerative potential of the neonatal mouse heart.

Porrello ER, Mahmoud AI, Simpson E, Hill JA, Richardson JA, Olson EN, Sadek HA.

Science. 2011 Feb 25;331(6020):1078-80. doi: 10.1126/science.1200708.

39.

The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

Simsek T, Kocabas F, Zheng J, Deberardinis RJ, Mahmoud AI, Olson EN, Schneider JW, Zhang CC, Sadek HA.

Cell Stem Cell. 2010 Sep 3;7(3):380-90. doi: 10.1016/j.stem.2010.07.011.

40.

Bone-marrow-derived side population cells for myocardial regeneration.

Sadek HA, Martin CM, Latif SS, Garry MG, Garry DJ.

J Cardiovasc Transl Res. 2009 Jun;2(2):173-81. doi: 10.1007/s12265-009-9090-0. Epub 2009 Mar 19.

41.

Letter by Sadek and Garry regarding article, "Iron-oxide labeling and outcome of transplanted mesenchymal stem cells in the infarcted myocardium".

Sadek HA, Garry DJ.

Circulation. 2008 Apr 8;117(14):e306; author reply e307. doi: 10.1161/CIRCULATIONAHA.107.750380. No abstract available.

PMID:
18391117
42.

Real time embolization of a mitral valve vegetation.

Sadek HA, Hoit BD.

Echocardiography. 2007 Aug;24(7):768-9. No abstract available.

PMID:
17651108
43.

Rheumatic manifestations of psoriasis.

Sadek HA, Abdel-Nasser AM, El-Amawy TA, Hassan SZ.

Clin Rheumatol. 2007 Apr;26(4):488-98. Epub 2006 May 3.

PMID:
16670829
45.

Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate.

Nulton-Persson AC, Szweda LI, Sadek HA.

J Cardiovasc Pharmacol. 2004 Nov;44(5):591-5.

PMID:
15505497
46.
47.

Cardiac ischemia/reperfusion, aging, and redox-dependent alterations in mitochondrial function.

Sadek HA, Nulton-Persson AC, Szweda PA, Szweda LI.

Arch Biochem Biophys. 2003 Dec 15;420(2):201-8. Review. No abstract available.

PMID:
14654058
48.

Selective inactivation of redox-sensitive mitochondrial enzymes during cardiac reperfusion.

Sadek HA, Humphries KM, Szweda PA, Szweda LI.

Arch Biochem Biophys. 2002 Oct 15;406(2):222-8.

PMID:
12361710
49.

Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion.

Bulteau AL, Lundberg KC, Humphries KM, Sadek HA, Szweda PA, Friguet B, Szweda LI.

J Biol Chem. 2001 Aug 10;276(32):30057-63. Epub 2001 May 25.

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