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Items: 1 to 50 of 83

1.

Biochemical and computational insights of adenosine deaminase inhibition by Epigallocatechin gallate.

K G A, C S S, J A, C S.

Comput Biol Chem. 2019 Aug 17;83:107111. doi: 10.1016/j.compbiolchem.2019.107111. [Epub ahead of print]

PMID:
31445420
2.

Endovascular Ultraviolet Laser-Facilitated Reversal of Vasospasm Induced by Subarachnoid Hemorrhage in Canines.

Watson BD, Sadasivan C, Hurst RW.

Acta Neurochir Suppl. 2020;127:127-138. doi: 10.1007/978-3-030-04615-6_19.

PMID:
31407073
3.

Angiographic assessment of the efficacy of flow diverter treatment for cerebral aneurysms.

Sadasivan C, Dholakia R, Peeling L, Gölitz P, Doerfler A, Lieber BB, Fiorella DJ, Woo HH.

Interv Neuroradiol. 2019 Jul 11:1591019919860829. doi: 10.1177/1591019919860829. [Epub ahead of print]

PMID:
31296064
4.

Pyridine derivatives as anticancer lead compounds with Fatty Acid Synthase as the target: An in silico-guided in vitro study.

Amrutha NA, Archana PR, Mohan SG, Anto RJ, Sadasivan C.

J Cell Biochem. 2019 Oct;120(10):16643-16657. doi: 10.1002/jcb.28923. Epub 2019 May 16.

PMID:
31095793
5.

Asthma and youth soccer: an investigation into the level of asthma awareness and training among youth soccer coaches.

Sadasivan C, Cave A.

Open Access J Sports Med. 2019 Jan 15;10:17-31. doi: 10.2147/OAJSM.S182178. eCollection 2019.

6.

Indole fragments for the design of lead molecules against pancreatitis.

Dileep KV, Ashok S, Remya C, Dharmendra KY, Pérez-Sánchez H, Sadasivan C.

J Biomol Struct Dyn. 2019 Jan 11:1-5. doi: 10.1080/07391102.2019.1567389. [Epub ahead of print]

PMID:
30633717
7.

The truth and fiction in aspiration physics: may the forces be with you.

Kallmes DF, Sadasivan C, Fiorella D.

J Neurointerv Surg. 2018 Nov;10(11):1029-1030. doi: 10.1136/neurintsurg-2018-014446. No abstract available.

PMID:
30309996
8.

In silico screening for identification of fatty acid synthase inhibitors and evaluation of their antiproliferative activity using human cancer cell lines.

Nisthul A A, Retnakumari AP, A S, Anto RJ, Sadasivan C.

J Recept Signal Transduct Res. 2018 Aug;38(4):335-341. doi: 10.1080/10799893.2018.1511730. Epub 2018 Sep 26.

PMID:
30256698
9.

Crystal structure of phospholipase A2 in complex with 1-naphthaleneacetic acid.

Dileep KV, Remya C, Tintu I, Mandal PK, Karthe P, Haridas M, Sadasivan C.

IUBMB Life. 2018 Oct;70(10):995-1001. doi: 10.1002/iub.1924. Epub 2018 Aug 18.

10.

Computational and experimental validation of morin as adenosine deaminase inhibitor.

Arun KG, Sharanya CS, Sadasivan C.

J Recept Signal Transduct Res. 2018 Jun;38(3):240-245. doi: 10.1080/10799893.2018.1476543. Epub 2018 May 29.

PMID:
29843562
11.

Realistic Vascular Replicator for TAVR Procedures.

Rotman OM, Kovarovic B, Sadasivan C, Gruberg L, Lieber BB, Bluestein D.

Cardiovasc Eng Technol. 2018 Sep;9(3):339-350. doi: 10.1007/s13239-018-0356-z. Epub 2018 Apr 13.

12.

Pressure and Flow Rate Changes During Contrast Injections in Cerebral Angiography: Correlation to Reflux Length.

Kovarovic B, Woo HH, Fiorella D, Lieber BB, Sadasivan C.

Cardiovasc Eng Technol. 2018 Jun;9(2):226-239. doi: 10.1007/s13239-018-0344-3. Epub 2018 Mar 1.

PMID:
29497965
13.

In vitro measurement of the permeability of endovascular coils deployed in cerebral aneurysms.

Sadasivan C, Swartwout E, Kappel AD, Woo HH, Fiorella DJ, Lieber BB.

J Neurointerv Surg. 2018 Sep;10(9):896-900. doi: 10.1136/neurintsurg-2017-013481. Epub 2018 Jan 3.

PMID:
29298858
14.

In vitro angiographic comparison of the flow-diversion performance of five neurovascular stents.

Dholakia RJ, Kappel AD, Pagano A, Woo HH, Lieber BB, Fiorella DJ, Sadasivan C.

Interv Neuroradiol. 2018 Apr;24(2):150-161. doi: 10.1177/1591019917748317. Epub 2017 Dec 14.

15.

Cellular calcium signaling in the aging brain.

Chandran R, Kumar M, Kesavan L, Jacob RS, Gunasekaran S, Lakshmi S, Sadasivan C, Omkumar RV.

J Chem Neuroanat. 2019 Jan;95:95-114. doi: 10.1016/j.jchemneu.2017.11.008. Epub 2017 Nov 9. Review.

PMID:
29129748
16.

Streptococcus pneumoniae surface protein PfbA is a versatile multidomain and multiligand-binding adhesin employing different binding mechanisms.

Beulin DSJ, Radhakrishnan D, Suresh SC, Sadasivan C, Yamaguchi M, Kawabata S, Ponnuraj K.

FEBS J. 2017 Oct;284(20):3404-3421. doi: 10.1111/febs.14200. Epub 2017 Sep 18.

17.

Novel tacrine derivatives exhibiting improved acetylcholinesterase inhibition: Design, synthesis and biological evaluation.

Reddy EK, Remya C, Mantosh K, Sajith AM, Omkumar RV, Sadasivan C, Anwar S.

Eur J Med Chem. 2017 Oct 20;139:367-377. doi: 10.1016/j.ejmech.2017.08.013. Epub 2017 Aug 5.

PMID:
28810188
18.

Hemodynamics of Flow Diverters.

Dholakia R, Sadasivan C, Fiorella DJ, Woo HH, Lieber BB.

J Biomech Eng. 2017 Feb 1;139(2). doi: 10.1115/1.4034932.

PMID:
27727400
19.

Inhibitory activity of hibifolin on adenosine deaminase- experimental and molecular modeling study.

Arun KG, Sharanya CS, Sandeep PM, Sadasivan C.

Comput Biol Chem. 2016 Oct;64:353-358. doi: 10.1016/j.compbiolchem.2016.08.005. Epub 2016 Aug 22.

PMID:
27591790
20.

Gallic acid binding to Spatholobus parviflorus lectin provides insight to its quaternary structure forming.

Surya S, Geethanandan K, Sadasivan C, Haridas M.

Int J Biol Macromol. 2016 Oct;91:696-702. doi: 10.1016/j.ijbiomac.2016.06.010. Epub 2016 Jun 6.

PMID:
27283232
21.

Trichoderma viride Laccase Plays a Crucial Role in Defense Mechanism against Antagonistic Organisms.

Divya L, Sadasivan C.

Front Microbiol. 2016 May 17;7:741. doi: 10.3389/fmicb.2016.00741. eCollection 2016.

22.

A profile of protein-protein interaction: Crystal structure of a lectin-lectin complex.

Surya S, Abhilash J, Geethanandan K, Sadasivan C, Haridas M.

Int J Biol Macromol. 2016 Jun;87:529-36. doi: 10.1016/j.ijbiomac.2016.02.081. Epub 2016 Mar 2.

PMID:
26945504
23.

Comparative studies on the inhibitory activities of selected benzoic acid derivatives against secretory phospholipase A2, a key enzyme involved in the inflammatory pathway.

Dileep KV, Remya C, Cerezo J, Fassihi A, Pérez-Sánchez H, Sadasivan C.

Mol Biosyst. 2015 Jul;11(7):1973-9. doi: 10.1039/c5mb00073d.

PMID:
25927625
24.

Flavanone glycosides as acetylcholinesterase inhibitors: computational and experimental evidence.

Remya C, Dileep KV, Tintu I, Variyar EJ, Sadasivan C.

Indian J Pharm Sci. 2014 Nov-Dec;76(6):567-70.

25.

TRAIL-based tumor sensitizing galactoxyloglucan, a novel entity for targeting apoptotic machinery.

Aravind SR, Joseph MM, George SK, Dileep KV, Varghese S, Rose-James A, Balaram P, Sadasivan C, Sreelekha TT.

Int J Biochem Cell Biol. 2015 Feb;59:153-66. doi: 10.1016/j.biocel.2014.11.019. Epub 2014 Dec 23.

PMID:
25541375
26.

Derivatives form better lipoxygenase inhibitors than piperine: in vitro and in silico study.

Tomy MJ, Sharanya CS, Dileep KV, Prasanth S, Sabu A, Sadasivan C, Haridas M.

Chem Biol Drug Des. 2015 Jun;85(6):715-21. doi: 10.1111/cbdd.12455. Epub 2014 Nov 17.

PMID:
25327968
27.

The crystal structure of a lectin from Butea monosperma: insight into its glycosylation and binding of ligands.

Abhilash J, Geethanandan K, Bharath SR, Sabu A, Sadasivan C, Haridas M.

Int J Biol Macromol. 2015 Jan;72:1376-83.

PMID:
25316424
28.

Cuminaldehyde as a lipoxygenase inhibitor: in vitro and in silico validation.

Tomy MJ, Dileep KV, Prasanth S, Preethidan DS, Sabu A, Sadasivan C, Haridas M.

Appl Biochem Biotechnol. 2014 Sep;174(1):388-97. doi: 10.1007/s12010-014-1066-0. Epub 2014 Jul 31.

PMID:
25080377
30.

A lectin from Spatholobus parviflorus inhibits Aspergillus flavus α-amylase: enzyme kinetics and thermodynamic studies.

Tintu I, Abhilash J, Dileep KV, Augustine A, Haridas M, Sadasivan C.

Chem Biol Drug Des. 2014 Jul;84(1):116-22. doi: 10.1111/cbdd.12291. Epub 2014 Mar 13.

PMID:
24460654
31.

Interactions of selected indole derivatives with COX-2 and their in silico structure modifications towards the development of novel NSAIDs.

Dileep KV, Remya C, Tintu I, Sadasivan C.

J Biomol Struct Dyn. 2014;32(11):1855-63. doi: 10.1080/07391102.2013.839960. Epub 2013 Sep 20.

PMID:
24053423
32.

A long acting biodegradable controlled delivery of chitosan microspheres loaded with tetanus toxoide as model antigen.

Varma S, Sadasivan C.

Biomed Pharmacother. 2014 Mar;68(2):225-30. doi: 10.1016/j.biopha.2013.08.009. Epub 2013 Sep 3.

PMID:
24051124
33.

Carbohydrate binding and unfolding of Spatholobus parviflorus lectin: fluorescence and circular dichroism spectroscopic study.

K G, Joseph A, C S, Haridas M.

Appl Biochem Biotechnol. 2013 Sep;171(1):80-92. doi: 10.1007/s12010-013-0340-x. Epub 2013 Jul 2.

PMID:
23817785
34.

Potential of the salt-tolerant laccase-producing strain Trichoderma viride Pers. NFCCI-2745 from an estuary in the bioremediation of phenol-polluted environments.

Divya LM, Prasanth GK, Sadasivan C.

J Basic Microbiol. 2014 Jun;54(6):542-7. doi: 10.1002/jobm.201200394. Epub 2013 May 26.

PMID:
23712577
35.

IN VITRO QUANTIFICATION OF THE SIZE DISTRIBUTION OF INTRASACCULAR VOIDS LEFT AFTER ENDOVASCULAR COILING OF CEREBRAL ANEURYSMS.

Sadasivan C, Brownstein J, Patel B, Dholakia R, Santore J, Al-Mufti F, Puig E, Rakian A, Fernandez-Prada KD, Elhammady MS, Farhat H, Fiorella DJ, Woo HH, Aziz-Sultan MA, Lieber BB.

Cardiovasc Eng Technol. 2013 Mar 1;4(1):63-74.

36.

Metal ions in sugar binding, sugar specificity and structural stability of Spatholobus parviflorus seed lectin.

Abhilash J, Dileep KV, Palanimuthu M, Geethanandan K, Sadasivan C, Haridas M.

J Mol Model. 2013 Aug;19(8):3271-8. doi: 10.1007/s00894-013-1854-4. Epub 2013 May 8.

PMID:
23652482
37.

Physical factors effecting cerebral aneurysm pathophysiology.

Sadasivan C, Fiorella DJ, Woo HH, Lieber BB.

Ann Biomed Eng. 2013 Jul;41(7):1347-65. doi: 10.1007/s10439-013-0800-z. Epub 2013 Apr 3. Review.

38.

Gossypin as a novel selective dual inhibitor of V-RAF murine sarcoma viral oncogene homolog B1 and cyclin-dependent kinase 4 for melanoma.

Bhaskaran S, Dileep KV, Deepa SS, Sadasivan C, Klausner M, Krishnegowda NK, Tekmal RR, VandeBerg JL, Nair HB.

Mol Cancer Ther. 2013 Apr;12(4):361-72. doi: 10.1158/1535-7163.MCT-12-0965. Epub 2013 Mar 29.

39.

Evaluation of biotransformed berberine derivatives as anti inflammatory drugs: an in silico study.

Naveen CD, Prasanth GK, Sadasivan C, Haridas M.

Interdiscip Sci. 2012 Dec;4(4):268-72. doi: 10.1007/s12539-012-0142-9. Epub 2013 Jan 26.

PMID:
23354815
40.

Interactions of selected indole derivatives with phospholipase A₂: in silico and in vitro analysis.

Dileep KV, Remya C, Tintu I, Haridas M, Sadasivan C.

J Mol Model. 2013 Apr;19(4):1811-7. doi: 10.1007/s00894-012-1741-4. Epub 2013 Jan 13.

PMID:
23315198
41.

Elimination of estrogenic activity of thermal paper using laccase from Trichoderma sp NFCCI-2745.

Divya LM, Prasanth GK, Sadasivan C.

Appl Biochem Biotechnol. 2013 Feb;169(4):1126-33. doi: 10.1007/s12010-012-0016-y. Epub 2013 Jan 10.

PMID:
23306877
42.

In vitro inhibitory profile of NDGA against AChE and its in silico structural modifications based on ADME profile.

Remya C, Dileep KV, Tintu I, Variyar EJ, Sadasivan C.

J Mol Model. 2013 Mar;19(3):1179-94. doi: 10.1007/s00894-012-1656-0. Epub 2012 Nov 16.

PMID:
23229229
43.

Comparison of the in vitro hemodynamic performance of new flow diverters for bypass of brain aneurysms.

Trager AL, Sadasivan C, Lieber BB.

J Biomech Eng. 2012 Aug;134(8):084505. doi: 10.1115/1.4006454.

44.

An isoquinoline alkaloid, berberine, can inhibit fungal alpha amylase: enzyme kinetic and molecular modeling studies.

Tintu I, Dileep KV, Augustine A, Sadasivan C.

Chem Biol Drug Des. 2012 Oct;80(4):554-60. doi: 10.1111/j.1747-0285.2012.01426.x. Epub 2012 Jul 23.

PMID:
22690956
45.

Anti-inflammatory property of n-hexadecanoic acid: structural evidence and kinetic assessment.

Aparna V, Dileep KV, Mandal PK, Karthe P, Sadasivan C, Haridas M.

Chem Biol Drug Des. 2012 Sep;80(3):434-9. doi: 10.1111/j.1747-0285.2012.01418.x. Epub 2012 Jun 27.

PMID:
22642495
46.

Inverted binding due to a minor structural change in berberine enhances its phospholipase A2 inhibitory effect.

Chandra DN, Abhilash J, Prasanth GK, Sabu A, Sadasivan C, Haridas M.

Int J Biol Macromol. 2012 Apr 1;50(3):578-85. doi: 10.1016/j.ijbiomac.2012.01.029. Epub 2012 Jan 26.

PMID:
22305795
47.

Binding to PLA2 may contribute to the anti-inflammatory activity of catechol.

Dileep KV, Tintu I, Mandal PK, Karthe P, Haridas M, Sadasivan C.

Chem Biol Drug Des. 2012 Jan;79(1):143-7. doi: 10.1111/j.1747-0285.2011.01258.x. Epub 2011 Nov 16.

PMID:
21995306
48.

Molecular docking studies of curcumin analogs with phospholipase A2.

Dileep KV, Tintu I, Sadasivan C.

Interdiscip Sci. 2011 Sep;3(3):189-97. doi: 10.1007/s12539-011-0090-9. Epub 2011 Sep 29.

PMID:
21956741
49.

X-ray structure of a galactose-specific lectin from Spatholobous parviflorous.

Geethanandan K, Abhilash J, Bharath SR, Sadasivan C, Haridas M.

Int J Biol Macromol. 2011 Dec 1;49(5):992-8. doi: 10.1016/j.ijbiomac.2011.08.021. Epub 2011 Aug 26.

PMID:
21889532
50.

Crystallization and preliminary X-ray studies of a galactose-specific lectin from the seeds of Spatholobus parviflorus.

Geethanandan K, Abhilash J, Bharath SR, Sadasivan C, Haridas M.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jun 1;67(Pt 6):700-2. doi: 10.1107/S174430911101387X. Epub 2011 May 26.

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