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Items: 33

1.

Excellent Response to Nivolumab and Ipilimumab in Metastatic Gastroesophageal Junction Squamous Carcinoma.

Sadagopan N, Devoe C.

Case Rep Oncol Med. 2019 Jul 11;2019:7405652. doi: 10.1155/2019/7405652. eCollection 2019.

2.

A robust and efficient method for estimating enzyme complex abundance and metabolic flux from expression data.

Barker BE, Sadagopan N, Wang Y, Smallbone K, Myers CR, Xi H, Locasale JW, Gu Z.

Comput Biol Chem. 2015 Dec;59 Pt B:98-112. doi: 10.1016/j.compbiolchem.2015.08.002. Epub 2015 Sep 1.

3.

Speech Practice Effects on Bilingual Children's Fast Mapping Performance.

Kan PF, Sadagopan N.

Semin Speech Lang. 2015 May;36(2):109-19. doi: 10.1055/s-0035-1549106. Epub 2015 Apr 29.

PMID:
25922996
4.

Novel word retention in bilingual and monolingual speakers.

Kan PF, Sadagopan N.

Front Psychol. 2014 Sep 29;5:1024. doi: 10.3389/fpsyg.2014.01024. eCollection 2014.

5.

Effects of speech practice on fast mapping in monolingual and bilingual speakers.

Kan PF, Sadagopan N, Janich L, Andrade M.

J Speech Lang Hear Res. 2014 Jun 1;57(3):929-41. doi: 10.1044/2013_JSLHR-L-13-0045.

PMID:
24167242
6.

Age differences in speech motor performance on a novel speech task.

Sadagopan N, Smith A.

J Speech Lang Hear Res. 2013 Oct;56(5):1552-66. doi: 10.1044/1092-4388(2013/12-0293). Epub 2013 Sep 10.

PMID:
24023373
7.

Discovery of potent selective bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model. Part II: optimization studies and demonstration of in vivo efficacy.

Plummer MS, Cornicelli J, Roark H, Skalitzky DJ, Stankovic CJ, Bove S, Pandit J, Goodman A, Hicks J, Shahripour A, Beidler D, Lu XK, Sanchez B, Whitehead C, Sarver R, Braden T, Gowan R, Shen XQ, Welch K, Ogden A, Sadagopan N, Baum H, Miller H, Banotai C, Spessard C, Lightle S.

Bioorg Med Chem Lett. 2013 Jun 1;23(11):3443-7. doi: 10.1016/j.bmcl.2013.03.082. Epub 2013 Mar 29.

PMID:
23597790
8.

Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, part I: transformation of selective pyrazolodiazepinone phosphodiesterase 4 (PDE4) inhibitors into selective PDE2 inhibitors.

Plummer MS, Cornicelli J, Roark H, Skalitzky DJ, Stankovic CJ, Bove S, Pandit J, Goodman A, Hicks J, Shahripour A, Beidler D, Lu XK, Sanchez B, Whitehead C, Sarver R, Braden T, Gowan R, Shen XQ, Welch K, Ogden A, Sadagopan N, Baum H, Miller H, Banotai C, Spessard C, Lightle S.

Bioorg Med Chem Lett. 2013 Jun 1;23(11):3438-42. doi: 10.1016/j.bmcl.2013.03.072. Epub 2013 Mar 28.

PMID:
23582272
9.

Focus of attention and speech motor performance.

Lisman AL, Sadagopan N.

J Commun Disord. 2013 May-Jun;46(3):281-93. doi: 10.1016/j.jcomdis.2013.02.002. Epub 2013 Feb 24.

PMID:
23497961
10.

Development of a multiplex UPLC-MRM MS method for quantification of human membrane transport proteins OATP1B1, OATP1B3 and OATP2B1 in in vitro systems and tissues.

Ji C, Tschantz WR, Pfeifer ND, Ullah M, Sadagopan N.

Anal Chim Acta. 2012 Mar 2;717:67-76. doi: 10.1016/j.aca.2011.12.005. Epub 2011 Dec 24.

PMID:
22304817
11.

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor.

Johnson DS, Stiff C, Lazerwith SE, Kesten SR, Fay LK, Morris M, Beidler D, Liimatta MB, Smith SE, Dudley DT, Sadagopan N, Bhattachar SN, Kesten SJ, Nomanbhoy TK, Cravatt BF, Ahn K.

ACS Med Chem Lett. 2011 Feb 10;2(2):91-96.

12.

Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain.

Ahn K, Smith SE, Liimatta MB, Beidler D, Sadagopan N, Dudley DT, Young T, Wren P, Zhang Y, Swaney S, Van Becelaere K, Blankman JL, Nomura DK, Bhattachar SN, Stiff C, Nomanbhoy TK, Weerapana E, Johnson DS, Cravatt BF.

J Pharmacol Exp Ther. 2011 Jul;338(1):114-24. doi: 10.1124/jpet.111.180257. Epub 2011 Apr 19.

13.

Nonword repetition in children and adults: effects on movement coordination.

Sasisekaran J, Smith A, Sadagopan N, Weber-Fox C.

Dev Sci. 2010 May;13(3):521-532. doi: 10.1111/j.1467-7687.2009.00911.x.

14.

Increasing phonological complexity reveals heightened instability in inter-articulatory coordination in adults who stutter.

Smith A, Sadagopan N, Walsh B, Weber-Fox C.

J Fluency Disord. 2010 Mar;35(1):1-18. doi: 10.1016/j.jfludis.2009.12.001. Epub 2009 Dec 22.

16.

Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.

Ahn K, Johnson DS, Mileni M, Beidler D, Long JZ, McKinney MK, Weerapana E, Sadagopan N, Liimatta M, Smith SE, Lazerwith S, Stiff C, Kamtekar S, Bhattacharya K, Zhang Y, Swaney S, Van Becelaere K, Stevens RC, Cravatt BF.

Chem Biol. 2009 Apr 24;16(4):411-20. doi: 10.1016/j.chembiol.2009.02.013.

17.

Development and validation of an LC-MS/MS method for quantification of cyclic guanosine 3',5'-monophosphate (cGMP) in clinical applications: a comparison with a EIA method.

Zhang Y, Dufield D, Klover J, Li W, Szekely-Klepser G, Lepsy C, Sadagopan N.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Feb 15;877(5-6):513-20. doi: 10.1016/j.jchromb.2008.12.063. Epub 2009 Jan 6.

PMID:
19179124
18.

Developmental changes in the effects of utterance length and complexity on speech movement variability.

Sadagopan N, Smith A.

J Speech Lang Hear Res. 2008 Oct;51(5):1138-51. doi: 10.1044/1092-4388(2008/06-0222). Epub 2008 Jul 29.

PMID:
18664705
19.

Circulating succinate is elevated in rodent models of hypertension and metabolic disease.

Sadagopan N, Li W, Roberds SL, Major T, Preston GM, Yu Y, Tones MA.

Am J Hypertens. 2007 Nov;20(11):1209-15.

PMID:
17954369
20.

Analytical approaches to determine cytochrome P450 inhibitory potential of new chemical entities in drug discovery.

Smith D, Sadagopan N, Zientek M, Reddy A, Cohen L.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):455-63. Epub 2006 Dec 30.

PMID:
17270503
21.
22.

An efficient approach for the rapid assessment of oral rat exposures for new chemical entities in drug discovery.

Han HK, Sadagopan N, Reichard GA, Yapa U, Zhu T, Hubbel A, Johnson K, Brodfuehrer J.

J Pharm Sci. 2006 Aug;95(8):1684-92.

PMID:
16732590
23.

Evaluation of online extraction/mass spectrometry for in vivo cassette analysis.

Sadagopan N, Pabst B, Cohen L.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jun 5;820(1):59-67. Epub 2005 Apr 18.

PMID:
15866493
24.

In vitro ADME phenotyping in drug discovery: current challenges and future solutions.

Williams JA, Bauman J, Cai H, Conlon K, Hansel S, Hurst S, Sadagopan N, Tugnait M, Zhang L, Sahi J.

Curr Opin Drug Discov Devel. 2005 Jan;8(1):78-88. Review.

PMID:
15679175
25.

Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo.

Sahi J, Stern RH, Milad MA, Rose KA, Gibson G, Zheng X, Stilgenbauer L, Sadagopan N, Jolley S, Gilbert D, LeCluyse EL.

Drug Metab Dispos. 2004 Dec;32(12):1370-6. Epub 2004 Aug 27.

PMID:
15333513
26.

Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line.

Mills JB, Rose KA, Sadagopan N, Sahi J, de Morais SM.

J Pharmacol Exp Ther. 2004 Apr;309(1):303-9. Epub 2004 Jan 13.

PMID:
14722322
27.

Beginning to communicate after cochlear implantation: oral language development in a young child.

Ertmer DJ, Strong LM, Sadagopan N.

J Speech Lang Hear Res. 2003 Apr;46(2):328-40.

PMID:
14700375
28.

Investigation of EDTA anticoagulant in plasma to improve the throughput of liquid chromatography/tandem mass spectrometric assays.

Sadagopan NP, Li W, Cook JA, Galvan B, Weller DL, Fountain ST, Cohen LH.

Rapid Commun Mass Spectrom. 2003;17(10):1065-70.

PMID:
12720287
29.

Liquid chromatography-tandem mass spectrometric quantitation of cyclophosphamide and its hydroxy metabolite in plasma and tissue for determination of tissue distribution.

Sadagopan N, Cohen L, Roberts B, Collard W, Omer C.

J Chromatogr B Biomed Sci Appl. 2001 Aug 15;759(2):277-84.

PMID:
11499481
30.

Mass spectrometric evidence for mechanisms of fragmentation of charge-derivatized peptides.

Sadagopan N, Watson JT.

J Am Soc Mass Spectrom. 2001 Apr;12(4):399-409.

32.
33.

Charge derivatization of peptides for analysis by mass spectrometry.

Roth KD, Huang ZH, Sadagopan N, Watson JT.

Mass Spectrom Rev. 1998 Jul-Aug;17(4):255-74. Review.

PMID:
10224676

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