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Items: 1 to 50 of 268

1.

Mitochondrial GCN5L1 regulates glutaminolysis, mTORC1 activity and murine liver regeneration.

Wang L, Zhu L, Wu K, Chen Y, Lee DY, Gucek M, Sack MN.

Hepatology. 2019 Jul 25. doi: 10.1002/hep.30876. [Epub ahead of print]

PMID:
31344750
2.

The glutamate to γ-aminobutyric acid ratio in the posterior insula is associated with pain perception in healthy women but not in women with borderline personality disorder.

Gradinger T, Sack M, Cardinale V, Thiacourt M, Baumgärtner U, Schmahl C, Ende G.

Pain. 2019 Jun 5. doi: 10.1097/j.pain.0000000000001641. [Epub ahead of print]

PMID:
31339871
3.

Differences between ketamine's short-term and long-term effects on brain circuitry in depression.

Gass N, Becker R, Reinwald J, Cosa-Linan A, Sack M, Weber-Fahr W, Vollmayr B, Sartorius A.

Transl Psychiatry. 2019 Jun 28;9(1):172. doi: 10.1038/s41398-019-0506-6.

4.

Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling.

Manning JR, Thapa D, Zhang M, Stoner MW, Traba J, Corey C, Shiva S, Sack MN, Scott I.

Biochem J. 2019 Jun 19;476(12):1713-1724. doi: 10.1042/BCJ20190302.

PMID:
31138772
5.

Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites.

Mikkelsen M, Rimbault DL, Barker PB, Bhattacharyya PK, Brix MK, Buur PF, Cecil KM, Chan KL, Chen DY, Craven AR, Cuypers K, Dacko M, Duncan NW, Dydak U, Edmondson DA, Ende G, Ersland L, Forbes MA, Gao F, Greenhouse I, Harris AD, He N, Heba S, Hoggard N, Hsu TW, Jansen JFA, Kangarlu A, Lange T, Lebel RM, Li Y, Lin CE, Liou JK, Lirng JF, Liu F, Long JR, Ma R, Maes C, Moreno-Ortega M, Murray SO, Noah S, Noeske R, Noseworthy MD, Oeltzschner G, Porges EC, Prisciandaro JJ, Puts NAJ, Roberts TPL, Sack M, Sailasuta N, Saleh MG, Schallmo MP, Simard N, Stoffers D, Swinnen SP, Tegenthoff M, Truong P, Wang G, Wilkinson ID, Wittsack HJ, Woods AJ, Xu H, Yan F, Zhang C, Zipunnikov V, Zöllner HJ, Edden RAE.

Neuroimage. 2019 May 1;191:537-548. doi: 10.1016/j.neuroimage.2019.02.059. Epub 2019 Mar 3.

PMID:
30840905
6.

Cardiac-specific deletion of GCN5L1 restricts recovery from ischemia-reperfusion injury.

Manning JR, Thapa D, Zhang M, Stoner MW, Traba J, McTiernan CF, Corey C, Shiva S, Sack MN, Scott I.

J Mol Cell Cardiol. 2019 Apr;129:69-78. doi: 10.1016/j.yjmcc.2019.02.009. Epub 2019 Feb 15.

PMID:
30776374
7.

A tetracycline-dependent ribozyme switch allows conditional induction of gene expression in Caenorhabditis elegans.

Wurmthaler LA, Sack M, Gense K, Hartig JS, Gamerdinger M.

Nat Commun. 2019 Jan 30;10(1):491. doi: 10.1038/s41467-019-08412-w.

8.

Plant cell packs: a scalable platform for recombinant protein production and metabolic engineering.

Rademacher T, Sack M, Blessing D, Fischer R, Holland T, Buyel J.

Plant Biotechnol J. 2019 Aug;17(8):1560-1566. doi: 10.1111/pbi.13081. Epub 2019 Feb 14.

9.

Neomycin-dependent hammerhead ribozymes for the direct control of gene expression in Saccharomyces cerevisiae.

Sack M, Stifel J, Kreft SG, Deuerling E, Hartig JS.

Methods. 2019 May 15;161:35-40. doi: 10.1016/j.ymeth.2019.01.004. Epub 2019 Jan 9.

PMID:
30639182
10.

In silico food allergenic risk evaluation of proteins extracted from macroalgae Ulva sp. with pulsed electric fields.

Polikovsky M, Fernand F, Sack M, Frey W, Müller G, Golberg A.

Food Chem. 2019 Mar 15;276:735-744. doi: 10.1016/j.foodchem.2018.09.134. Epub 2018 Sep 29.

PMID:
30409656
11.

Parkin targets NOD2 to regulate astrocyte endoplasmic reticulum stress and inflammation.

Singh K, Han K, Tilve S, Wu K, Geller HM, Sack MN.

Glia. 2018 Nov;66(11):2427-2437. doi: 10.1002/glia.23482. Epub 2018 Oct 30.

PMID:
30378174
12.

Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4+ T Cell Activation.

Akkaya B, Roesler AS, Miozzo P, Theall BP, Al Souz J, Smelkinson MG, Kabat J, Traba J, Sack MN, Brzostowski JA, Pena M, Dorward DW, Pierce SK, Akkaya M.

J Immunol. 2018 Dec 1;201(11):3294-3306. doi: 10.4049/jimmunol.1800753. Epub 2018 Oct 29.

PMID:
30373851
13.

GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking.

Wu K, Wang L, Chen Y, Pirooznia M, Singh K, Wälde S, Kehlenbach RH, Scott I, Gucek M, Sack MN.

J Cell Sci. 2018 Nov 20;131(22). pii: jcs221036. doi: 10.1242/jcs.221036.

14.

The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.

Thapa D, Wu K, Stoner MW, Xie B, Zhang M, Manning JR, Lu Z, Li JH, Chen Y, Gucek M, Playford MP, Mehta NN, Harmon D, O'Doherty RM, Jurczak MJ, Sack MN, Scott I.

J Biol Chem. 2018 Nov 16;293(46):17676-17684. doi: 10.1074/jbc.AC118.005462. Epub 2018 Oct 15.

15.

Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites.

Chouman K, Korioth-Schmitz B, Sack M, Schmitz JE, Pham AT, Fischer R, Barth S, Klockenbring T, Fendel R.

Eur Cytokine Netw. 2018 Jun 1;29(2):59-72. doi: 10.1684/ecn.2018.0409.

PMID:
30148452
16.

Glyco-Engineering of Plant-Based Expression Systems.

Fischer R, Holland T, Sack M, Schillberg S, Stoger E, Twyman RM, Buyel JF.

Adv Biochem Eng Biotechnol. 2018 Aug 2. doi: 10.1007/10_2018_76. [Epub ahead of print]

PMID:
30069741
17.

Mitochondrial fidelity and metabolic agility control immune cell fate and function.

Sack MN.

J Clin Invest. 2018 Aug 31;128(9):3651-3661. doi: 10.1172/JCI120845. Epub 2018 Jul 30. Review.

18.

A Pilot Study To Investigate the Immune-Modulatory Effects of Fasting in Steroid-Naive Mild Asthmatics.

Han K, Nguyen A, Traba J, Yao X, Kaler M, Huffstutler RD, Levine SJ, Sack MN.

J Immunol. 2018 Sep 1;201(5):1382-1388. doi: 10.4049/jimmunol.1800585. Epub 2018 Jul 18.

19.

The affinity of antipsychotic drugs to dopamine and serotonin 5-HT2 receptors determines their effects on prefrontal-striatal functional connectivity.

Tollens F, Gass N, Becker R, Schwarz AJ, Risterucci C, Künnecke B, Lebhardt P, Reinwald J, Sack M, Weber-Fahr W, Meyer-Lindenberg A, Sartorius A.

Eur Neuropsychopharmacol. 2018 Sep;28(9):1035-1046. doi: 10.1016/j.euroneuro.2018.05.016. Epub 2018 Jul 10.

PMID:
30006253
20.

Disconnected - Impaired Interoceptive Accuracy and Its Association With Self-Perception and Cardiac Vagal Tone in Patients With Dissociative Disorder.

Schäflein E, Sattel HC, Pollatos O, Sack M.

Front Psychol. 2018 Jun 27;9:897. doi: 10.3389/fpsyg.2018.00897. eCollection 2018.

21.

Second signals rescue B cells from activation-induced mitochondrial dysfunction and death.

Akkaya M, Traba J, Roesler AS, Miozzo P, Akkaya B, Theall BP, Sohn H, Pena M, Smelkinson M, Kabat J, Dahlstrom E, Dorward DW, Skinner J, Sack MN, Pierce SK.

Nat Immunol. 2018 Aug;19(8):871-884. doi: 10.1038/s41590-018-0156-5. Epub 2018 Jul 9.

22.

Glutamate concentration in the anterior cingulate cortex in alcohol dependence: association with alcohol withdrawal and exploration of contribution from glutamatergic candidate genes.

Streit F, Treutlein J, Frischknecht U, Hermann D, Mann K, Kiefer F, Sack M, Hall ASM, Frank J, Witt SH, Foo JC, Degenhardt F, Heilmann-Heimbach S, Nöthen MM, Sommer WH, Spanagel R, Rietschel M, Ende G.

Psychiatr Genet. 2018 Oct;28(5):94-95. doi: 10.1097/YPG.0000000000000202. No abstract available.

23.

CRISPR/Cas9-mediated knockout of six glycosyltransferase genes in Nicotiana benthamiana for the production of recombinant proteins lacking β-1,2-xylose and core α-1,3-fucose.

Jansing J, Sack M, Augustine SM, Fischer R, Bortesi L.

Plant Biotechnol J. 2019 Feb;17(2):350-361. doi: 10.1111/pbi.12981. Epub 2018 Aug 11.

24.

The enemy in the mirror: self-perception-induced stress results in dissociation of psychological and physiological responses in patients with dissociative disorder.

Schäflein E, Sattel H, Schmidt U, Sack M.

Eur J Psychotraumatol. 2018 Jun 18;9(Suppl 3):1472991. doi: 10.1080/20008198.2018.1472991. eCollection 2018.

25.

Longitudinal Structural and Functional Brain Network Alterations in a Mouse Model of Neuropathic Pain.

Bilbao A, Falfán-Melgoza C, Leixner S, Becker R, Singaravelu SK, Sack M, Sartorius A, Spanagel R, Weber-Fahr W.

Neuroscience. 2018 Sep 1;387:104-115. doi: 10.1016/j.neuroscience.2018.04.020. Epub 2018 Apr 22.

26.

Sarcoid-Like Mediastinal Lymphadenopathy in Gynecologic Malignancy.

Lashari BH, Asai M, Randleman G, Sack M, Patel R.

Pulm Med. 2018 Feb 14;2018:5141575. doi: 10.1155/2018/5141575. eCollection 2018.

27.

Lateral habenula perturbation reduces default-mode network connectivity in a rat model of depression.

Clemm von Hohenberg C, Weber-Fahr W, Lebhardt P, Ravi N, Braun U, Gass N, Becker R, Sack M, Cosa Linan A, Gerchen MF, Reinwald JR, Oettl LL, Meyer-Lindenberg A, Vollmayr B, Kelsch W, Sartorius A.

Transl Psychiatry. 2018 Mar 27;8(1):68. doi: 10.1038/s41398-018-0121-y.

28.

GCN5L1/BLOS1 Links Acetylation, Organelle Remodeling, and Metabolism.

Scott I, Wang L, Wu K, Thapa D, Sack MN.

Trends Cell Biol. 2018 May;28(5):346-355. doi: 10.1016/j.tcb.2018.01.007. Epub 2018 Feb 21. Review.

29.

Deashing macroalgae biomass by pulsed electric field treatment.

Robin A, Sack M, Israel A, Frey W, Müller G, Golberg A.

Bioresour Technol. 2018 May;255:131-139. doi: 10.1016/j.biortech.2018.01.089. Epub 2018 Feb 4.

PMID:
29414158
30.

Neural Mechanisms of Early-Life Social Stress as a Developmental Risk Factor for Severe Psychiatric Disorders.

Reinwald JR, Becker R, Mallien AS, Falfan-Melgoza C, Sack M, Clemm von Hohenberg C, Braun U, Cosa Linan A, Gass N, Vasilescu AN, Tollens F, Lebhardt P, Pfeiffer N, Inta D, Meyer-Lindenberg A, Gass P, Sartorius A, Weber-Fahr W.

Biol Psychiatry. 2018 Jul 15;84(2):116-128. doi: 10.1016/j.biopsych.2017.12.010. Epub 2017 Dec 28.

PMID:
29397900
31.

[Validation of the Screening for Complex PTSD (SkPTBS) - Revision].

Dorr F, Sack M, Bengel J.

Psychother Psychosom Med Psychol. 2018 Dec;68(12):525-533. doi: 10.1055/s-0043-122942. Epub 2018 Jan 19. German.

PMID:
29351709
32.

Antagonism at the NR2B subunit of NMDA receptors induces increased connectivity of the prefrontal and subcortical regions regulating reward behavior.

Gass N, Becker R, Sack M, Schwarz AJ, Reinwald J, Cosa-Linan A, Zheng L, von Hohenberg CC, Inta D, Meyer-Lindenberg A, Weber-Fahr W, Gass P, Sartorius A.

Psychopharmacology (Berl). 2018 Apr;235(4):1055-1068. doi: 10.1007/s00213-017-4823-2. Epub 2018 Jan 5.

PMID:
29305627
33.

ATP-degrading ENPP1 is required for survival (or persistence) of long-lived plasma cells.

Wang H, Gonzalez-Garcia I, Traba J, Jain S, Conteh S, Shin DM, Qi C, Gao Y, Sun J, Kang S, Abbasi S, Naghashfar Z, Yoon J, DuBois W, Kovalchuk AL, Sack MN, Duffy P, Morse HC 3rd.

Sci Rep. 2017 Dec 19;7(1):17867. doi: 10.1038/s41598-017-18028-z.

34.

Posterior Insular GABA Levels Inversely Correlate with the Intensity of Experimental Mechanical Pain in Healthy Subjects.

Thiaucourt M, Shabes P, Schloss N, Sack M, Baumgärtner U, Schmahl C, Ende G.

Neuroscience. 2018 Sep 1;387:116-122. doi: 10.1016/j.neuroscience.2017.09.043. Epub 2017 Oct 1.

PMID:
28978415
35.

GCN5L1 modulates cross-talk between mitochondria and cell signaling to regulate FoxO1 stability and gluconeogenesis.

Wang L, Scott I, Zhu L, Wu K, Han K, Chen Y, Gucek M, Sack MN.

Nat Commun. 2017 Sep 12;8(1):523. doi: 10.1038/s41467-017-00521-8.

36.

Big GABA: Edited MR spectroscopy at 24 research sites.

Mikkelsen M, Barker PB, Bhattacharyya PK, Brix MK, Buur PF, Cecil KM, Chan KL, Chen DY, Craven AR, Cuypers K, Dacko M, Duncan NW, Dydak U, Edmondson DA, Ende G, Ersland L, Gao F, Greenhouse I, Harris AD, He N, Heba S, Hoggard N, Hsu TW, Jansen JFA, Kangarlu A, Lange T, Lebel RM, Li Y, Lin CE, Liou JK, Lirng JF, Liu F, Ma R, Maes C, Moreno-Ortega M, Murray SO, Noah S, Noeske R, Noseworthy MD, Oeltzschner G, Prisciandaro JJ, Puts NAJ, Roberts TPL, Sack M, Sailasuta N, Saleh MG, Schallmo MP, Simard N, Swinnen SP, Tegenthoff M, Truong P, Wang G, Wilkinson ID, Wittsack HJ, Xu H, Yan F, Zhang C, Zipunnikov V, Zöllner HJ, Edden RAE.

Neuroimage. 2017 Oct 1;159:32-45. doi: 10.1016/j.neuroimage.2017.07.021. Epub 2017 Jul 14.

37.

Basic Biology of Oxidative Stress and the Cardiovascular System: Part 1 of a 3-Part Series.

Sack MN, Fyhrquist FY, Saijonmaa OJ, Fuster V, Kovacic JC.

J Am Coll Cardiol. 2017 Jul 11;70(2):196-211. doi: 10.1016/j.jacc.2017.05.034. Review.

38.

Prolonged fasting suppresses mitochondrial NLRP3 inflammasome assembly and activation via SIRT3-mediated activation of superoxide dismutase 2.

Traba J, Geiger SS, Kwarteng-Siaw M, Han K, Ra OH, Siegel RM, Gius D, Sack MN.

J Biol Chem. 2017 Jul 21;292(29):12153-12164. doi: 10.1074/jbc.M117.791715. Epub 2017 Jun 5.

39.

Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress.

Han K, Hassanzadeh S, Singh K, Menazza S, Nguyen TT, Stevens MV, Nguyen A, San H, Anderson SA, Lin Y, Zou J, Murphy E, Sack MN.

Sci Rep. 2017 May 18;7(1):2093. doi: 10.1038/s41598-017-02339-2.

40.

Antibodies from plants for bionanomaterials.

Edgue G, Twyman RM, Beiss V, Fischer R, Sack M.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Nov;9(6). doi: 10.1002/wnan.1462. Epub 2017 Mar 27. Review.

PMID:
28345261
41.
42.

Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats.

Frischknecht U, Hermann D, Tunc-Skarka N, Wang GY, Sack M, van Eijk J, Demirakca T, Falfan-Melgoza C, Krumm B, Dieter S, Spanagel R, Kiefer F, Mann KF, Sommer WH, Ende G, Weber-Fahr W.

Alcohol Clin Exp Res. 2017 Feb;41(2):323-333. doi: 10.1111/acer.13308. Epub 2017 Jan 18.

PMID:
28098946
43.

Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism.

Braig F, Kriegs M, Voigtlaender M, Habel B, Grob T, Biskup K, Blanchard V, Sack M, Thalhammer A, Ben Batalla I, Braren I, Laban S, Danielczyk A, Goletz S, Jakubowicz E, Märkl B, Trepel M, Knecht R, Riecken K, Fehse B, Loges S, Bokemeyer C, Binder M.

Cancer Res. 2017 Mar 1;77(5):1188-1199. doi: 10.1158/0008-5472.CAN-16-0754. Epub 2016 Dec 28.

44.

In vitro combinatory effects of the Alternaria mycotoxins alternariol and altertoxin II and potentially involved miRNAs.

Vejdovszky K, Sack M, Jarolim K, Aichinger G, Somoza MM, Marko D.

Toxicol Lett. 2017 Feb 5;267:45-52. doi: 10.1016/j.toxlet.2016.12.011. Epub 2016 Dec 19.

45.

The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome.

Traba J, Sack MN.

Cell Mol Life Sci. 2017 May;74(10):1777-1791. doi: 10.1007/s00018-016-2431-7. Epub 2016 Dec 10. Review.

46.

ACC GABA levels are associated with functional activation and connectivity in the fronto-striatal network during interference inhibition in patients with borderline personality disorder.

Wang GY, van Eijk J, Demirakca T, Sack M, Krause-Utz A, Cackowski S, Schmahl C, Ende G.

Neuroimage. 2017 Feb 15;147:164-174. doi: 10.1016/j.neuroimage.2016.12.013. Epub 2016 Dec 7.

PMID:
27940074
47.

A Comparison of Dual Attention, Eye Movements, and Exposure Only during Eye Movement Desensitization and Reprocessing for Posttraumatic Stress Disorder: Results from a Randomized Clinical Trial.

Sack M, Zehl S, Otti A, Lahmann C, Henningsen P, Kruse J, Stingl M.

Psychother Psychosom. 2016;85(6):357-365. Epub 2016 Oct 15.

PMID:
27744424
48.

Early effects of a high-caloric diet and physical exercise on brain volumetry and behavior: a combined MRI and histology study in mice.

Sack M, Lenz JN, Jakovcevski M, Biedermann SV, Falfán-Melgoza C, Deussing J, Bielohuby M, Bidlingmaier M, Pfister F, Stalla GK, Sartorius A, Gass P, Weber-Fahr W, Fuss J, Auer MK.

Brain Imaging Behav. 2017 Oct;11(5):1385-1396. doi: 10.1007/s11682-016-9638-y.

49.

The complementary and divergent roles of uncoupling proteins 1 and 3 in thermoregulation.

Riley CL, Dao C, Kenaston MA, Muto L, Kohno S, Nowinski SM, Solmonson AD, Pfeiffer M, Sack MN, Lu Z, Fiermonte G, Sprague JE, Mills EM.

J Physiol. 2016 Dec 15;594(24):7455-7464. doi: 10.1113/JP272971. Epub 2016 Nov 13.

50.

SNAP-Tag Technology: A Useful Tool To Determine Affinity Constants and Other Functional Parameters of Novel Antibody Fragments.

Niesen J, Sack M, Seidel M, Fendel R, Barth S, Fischer R, Stein C.

Bioconjug Chem. 2016 Aug 17;27(8):1931-41. doi: 10.1021/acs.bioconjchem.6b00315. Epub 2016 Jul 22.

PMID:
27391930

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