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Items: 15


Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.

Sacino AN, Prokop S, Walsh MA, Adamson J, Subramony SH, Krans A, Todd PK, Giasson BI, Yachnis AT.

Acta Neuropathol Commun. 2019 Oct 30;7(1):158. doi: 10.1186/s40478-019-0818-z.


Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils.

Dhillon JS, Trejo-Lopez JA, Riffe C, Levites Y, Sacino AN, Borchelt DR, Yachnis AY, Giasson BI.

Acta Neuropathol Commun. 2019 May 20;7(1):80. doi: 10.1186/s40478-019-0733-3.


Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration.

Sorrentino ZA, Xia Y, Funk C, Riffe CJ, Rutherford NJ, Ceballos Diaz C, Sacino AN, Price ND, Golde TE, Giasson BI, Chakrabarty P.

Neurobiol Dis. 2018 Dec;120:98-106. doi: 10.1016/j.nbd.2018.09.005. Epub 2018 Sep 6.


Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology.

Sacino AN, Brooks MM, Chakrabarty P, Saha K, Khoshbouei H, Golde TE, Giasson BI.

J Neurochem. 2017 Feb;140(4):662-678. doi: 10.1111/jnc.13743. Epub 2016 Aug 19.


Early Surgical Intervention for a Large Newborn Cephalohematoma.

Eseonu CI, Sacino AN, Ahn ES.

Pediatr Neurosurg. 2016;51(4):210-3. doi: 10.1159/000444195. Epub 2016 Mar 10.


Novel Application of a Reverse Triage Protocol Providing Increased Access to Care in an Outpatient, Primary Care Clinic Setting.

Sacino AN, Shuster JJ, Nowicki K, Carek PJ, Wegman MP, Listhaus A, Gibney JM, Chang KL.

Fam Med. 2016 Feb;48(2):136-9.


Non-prion-type transmission in A53T α-synuclein transgenic mice: a normal component of spinal homogenates from naïve non-transgenic mice induces robust α-synuclein pathology.

Sacino AN, Ayers JI, Brooks MM, Chakrabarty P, Hudson VJ 3rd, Howard JK, Golde TE, Giasson BI, Borchelt DR.

Acta Neuropathol. 2016 Jan;131(1):151-4. doi: 10.1007/s00401-015-1505-1. Epub 2015 Nov 5. No abstract available.


Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice.

Rutherford NJ, Sacino AN, Brooks M, Ceballos-Diaz C, Ladd TB, Howard JK, Golde TE, Giasson BI.

Mol Neurodegener. 2015 Jul 30;10:32. doi: 10.1186/s13024-015-0029-4.


Inefficient induction and spread of seeded tau pathology in P301L mouse model of tauopathy suggests inherent physiological barriers to transmission.

Chakrabarty P, Hudson VJ III, Sacino AN, Brooks MM, D'Alton S, Lewis J, Golde TE, Giasson BI.

Acta Neuropathol. 2015 Aug;130(2):303-5. doi: 10.1007/s00401-015-1444-x. Epub 2015 May 16. No abstract available.


Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker.

Sacino AN, Brooks M, McKinney AB, Thomas MA, Shaw G, Golde TE, Giasson BI.

J Neurosci. 2014 Sep 10;34(37):12368-78. doi: 10.1523/JNEUROSCI.2102-14.2014.


Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.

Sacino AN, Brooks M, Thomas MA, McKinney AB, Lee S, Regenhardt RW, McGarvey NH, Ayers JI, Notterpek L, Borchelt DR, Golde TE, Giasson BI.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10732-7. doi: 10.1073/pnas.1321785111. Epub 2014 Jul 7.


Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice.

Sacino AN, Brooks M, Thomas MA, McKinney AB, McGarvey NH, Rutherford NJ, Ceballos-Diaz C, Robertson J, Golde TE, Giasson BI.

Acta Neuropathol. 2014 May;127(5):645-65. Erratum in: Acta Neuropathol. 2014 Dec;128(6):897-8.


Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein.

Sacino AN, Brooks M, McGarvey NH, McKinney AB, Thomas MA, Levites Y, Ran Y, Golde TE, Giasson BI.

Acta Neuropathol Commun. 2013 Jul 17;1:38. doi: 10.1186/2051-5960-1-38.


Conformational templating of α-synuclein aggregates in neuronal-glial cultures.

Sacino AN, Thomas MA, Ceballos-Diaz C, Cruz PE, Rosario AM, Lewis J, Giasson BI, Golde TE.

Mol Neurodegener. 2013 May 28;8:17. doi: 10.1186/1750-1326-8-17.


Does a prion-like mechanism play a major role in the apparent spread of α-synuclein pathology?

Sacino AN, Giasson BI.

Alzheimers Res Ther. 2012 Dec 17;4(6):48. doi: 10.1186/alzrt151. eCollection 2012. Review.

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