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Items: 1 to 50 of 92

1.

Be alert to leukocyte antibodies when prescribing granulocyte transfusions.

Bux J, Sachs UJ.

Transfusion. 2019 Jun;59(6):2174. doi: 10.1111/trf.15239. No abstract available.

PMID:
31161669
2.

Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia.

Vollenberg R, Jouni R, Norris PAA, Burg-Roderfeld M, Cooper N, Rummel MJ, Bein G, Marini I, Bayat B, Burack R, Lazarus AH, Bakchoul T, Sachs UJ.

Haematologica. 2019 Jun;104(6):1237-1243. doi: 10.3324/haematol.2018.211086. Epub 2019 Mar 28.

3.

The nonconservative CD177 single-nucleotide polymorphism c.1291G>A is a genetic determinant for human neutrophil antigen-2 atypical/low expression and deficiency.

Wu J, Li Y, Schuller RM, Li L, Litmeyer AS, Bein G, Sachs UJ, Bayat B.

Transfusion. 2019 May;59(5):1836-1842. doi: 10.1111/trf.15222. Epub 2019 Mar 3.

PMID:
30828823
4.

Diagnosing Immune Thrombocytopenia.

Sachs UJ.

Hamostaseologie. 2019 Feb 14. doi: 10.1055/s-0039-1678739. [Epub ahead of print]

PMID:
30763966
5.

Unmatched Type O RhD+ Red Blood Cells in Multiple Injured Patients.

Flommersfeld S, Mand C, Kühne CA, Bein G, Ruchholtz S, Sachs UJ.

Transfus Med Hemother. 2018 May;45(3):158-161. doi: 10.1159/000485388. Epub 2018 Mar 7.

6.

Molecular and Functional Characterization of Fcγ Receptor IIIb-Ligand Interaction: Implications for Neutrophil-Mediated Immune Mechanisms in Malaria.

Simtong P, Romphruk AV, Traum A, Burg-Roderfeld M, Bein G, Jakubowski K, Dominik A, Theisen M, Kana IH, Sachs UJ, Santoso S.

Infect Immun. 2018 Jul 23;86(8). pii: e00924-17. doi: 10.1128/IAI.00924-17. Print 2018 Aug.

7.

Improvement of monoclonal antibody-immobilized granulocyte antigen assay for the detection of anti-HNA-1 alloantibodies.

Simtong P, Romphruk AV, Hofmann C, Reil A, Sachs UJ, Santoso S.

Transfusion. 2018 Jan;58(1):200-207. doi: 10.1111/trf.14428. Epub 2017 Dec 6.

PMID:
29210081
8.

Red blood cell alloimmunization in neonates and children up to 3 years of age.

Türkmen T, Qiu D, Cooper N, Sachs UJ, Wößmann W, Schranz D, Zimmer KP, Ehrhardt H, Hackstein H, Bein G.

Transfusion. 2017 Nov;57(11):2720-2726. doi: 10.1111/trf.14273. Epub 2017 Sep 6.

PMID:
28880379
9.

Patients with Bernard-Soulier syndrome and different severity of the bleeding phenotype.

Boeckelmann D, Hengartner H, Greinacher A, Nowak-Göttl U, Sachs UJ, Peter K, Sandrock-Lang K, Zieger B.

Blood Cells Mol Dis. 2017 Sep;67:69-74. doi: 10.1016/j.bcmd.2017.01.010. Epub 2017 Jan 22.

PMID:
28131619
10.

HLA-DRB3*01:01 is a predictor of immunization against human platelet antigen-1a but not of the severity of fetal and neonatal alloimmune thrombocytopenia.

Wienzek-Lischka S, König IR, Papenkort EM, Hackstein H, Santoso S, Sachs UJ, Bein G.

Transfusion. 2017 Mar;57(3):533-540. doi: 10.1111/trf.13950. Epub 2016 Dec 26.

PMID:
28019029
11.

A sequence-specific polymerase chain reaction method for HNA-2 genotyping: homozygous c.843A>T mutation predicts the absence of CD177.

Bayat B, Bein G, Sachs UJ.

Transfusion. 2016 Aug;56(8):2127-32. doi: 10.1111/trf.13689. Epub 2016 Jul 7.

PMID:
27385476
12.

Antiendothelial αvβ3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia.

Santoso S, Wihadmadyatami H, Bakchoul T, Werth S, Al-Fakhri N, Bein G, Kiefel V, Zhu J, Newman PJ, Bayat B, Sachs UJ.

Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1517-24. doi: 10.1161/ATVBAHA.116.307281. Epub 2016 Jun 9.

13.

Immunisation against αIIbβ3 and αvβ3 in a type 1 variant of Glanzmann's thrombasthenia caused by a missense mutation Gly540Asp on β3.

Wihadmadyatami H, Röder L, Berghöfer H, Bein G, Heidinger K, Sachs UJ, Santoso S.

Thromb Haemost. 2016 Aug 1;116(2):262-71. doi: 10.1160/TH15-12-0982. Epub 2016 Apr 21.

PMID:
27098940
14.

Update on the nomenclature of human neutrophil antigens and alleles.

Flesch BK, Curtis BR, de Haas M, Lucas G, Sachs UJ.

Transfusion. 2016 Jun;56(6):1477-9. doi: 10.1111/trf.13575. Epub 2016 Apr 4. No abstract available.

PMID:
27039828
15.

A bead-based assay in the work-up of suspected platelet alloimmunization.

Cooper N, Bein G, Heidinger K, Santoso S, Sachs UJ.

Transfusion. 2016 Jan;56(1):115-8. doi: 10.1111/trf.13351. Epub 2015 Nov 6.

PMID:
26545411
16.

Partially desulfated heparin modulates the interaction between anti-protamine/heparin antibodies and platelets.

Jouni R, Zöllner H, Khadour A, Wesche J, Grotevendt A, Brandt S, Delcea M, Krauel K, Schwertz H, Sachs UJ, Greinacher A, Bakchoul T.

Thromb Haemost. 2016 Jan;115(2):324-32. doi: 10.1160/TH15-07-0539. Epub 2015 Oct 1.

PMID:
26423467
17.

Alloantibody against new platelet alloantigen (Lap(a)) on glycoprotein IIb is responsible for a case of fetal and neonatal alloimmune thrombocytopenia.

Wihadmadyatami H, Heidinger K, Röder L, Werth S, Giptner A, Hackstein H, Knorr M, Bein G, Sachs UJ, Santoso S.

Transfusion. 2015 Dec;55(12):2920-9. doi: 10.1111/trf.13238. Epub 2015 Aug 6.

PMID:
26388194
18.

Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases.

Holzinger D, Fassl SK, de Jager W, Lohse P, Röhrig UF, Gattorno M, Omenetti A, Chiesa S, Schena F, Austermann J, Vogl T, Kuhns DB, Holland SM, Rodríguez-Gallego C, López-Almaraz R, Arostegui JI, Colino E, Roldan R, Fessatou S, Isidor B, Poignant S, Ito K, Epple HJ, Bernstein JA, Jeng M, Frankovich J, Lionetti G, Church JA, Ong PY, LaPlant M, Abinun M, Skinner R, Bigley V, Sachs UJ, Hinze C, Hoppenreijs E, Ehrchen J, Foell D, Chae JJ, Ombrello A, Aksentijevich I, Sunderkoetter C, Roth J.

J Allergy Clin Immunol. 2015 Nov;136(5):1337-45. doi: 10.1016/j.jaci.2015.04.016. Epub 2015 May 27.

PMID:
26025129
19.

Platelet destruction in immune thrombocytopenia. Understanding the mechanisms.

Bakchoul T, Sachs UJ.

Hamostaseologie. 2016 Aug 3;36(3):187-94. doi: 10.5482/HAMO-14-09-0043. Epub 2015 May 18. Review.

PMID:
25982994
20.

Choline Transporter-Like Protein-2: New von Willebrand Factor-Binding Partner Involved in Antibody-Mediated Neutrophil Activation and Transfusion-Related Acute Lung Injury.

Bayat B, Tjahjono Y, Berghöfer H, Werth S, Deckmyn H, De Meyer SF, Sachs UJ, Santoso S.

Arterioscler Thromb Vasc Biol. 2015 Jul;35(7):1616-22. doi: 10.1161/ATVBAHA.115.305259. Epub 2015 Apr 30.

PMID:
25931511
21.

Noninvasive fetal genotyping of human platelet antigen-1a using targeted massively parallel sequencing.

Wienzek-Lischka S, Krautwurst A, Fröhner V, Hackstein H, Gattenlöhner S, Bräuninger A, Axt-Fliedner R, Degenhardt J, Deisting C, Santoso S, Sachs UJ, Bein G.

Transfusion. 2015 Jun;55(6 Pt 2):1538-44. doi: 10.1111/trf.13102. Epub 2015 Apr 15.

PMID:
25873286
22.

Collection of peripheral blood progenitor cells on Day 4 is feasible and effective while reducing granulocyte-colony-stimulating factor exposure to healthy donors.

Flommersfeld S, Sohlbach K, Jaques G, Bein G, Hoffmann J, Kostrewa P, Sachs UJ.

Transfusion. 2015 Jun;55(6):1269-74. doi: 10.1111/trf.13002. Epub 2015 Feb 3.

PMID:
25647638
23.

Multicentric validation of a rapid assay for heparin-induced thrombocytopenia with different specimen types.

Kolde HJ, Habrecht U, von Hesberg J, Panzer S, Seidel H, Bakchoul T, Sachs UJ.

Blood Coagul Fibrinolysis. 2014 Jan;25(1):6-9. doi: 10.1097/MBC.0b013e32836577c8.

PMID:
24365772
24.

Non-transient "self-sustaining" heparin-induced thrombocytopenia: 4-year persistence of a platelet-activating PF4/heparin-antibody status without heparin exposure.

Birschmann I, Gummert J, Schirmer U, Knabbe C, Sachs UJ, Koster A.

Platelets. 2014;25(8):634-5. doi: 10.3109/09537104.2013.849803. Epub 2013 Nov 18.

PMID:
24246163
25.

Effectiveness of vitamin K in anticoagulation reversal for hip fracture surgery--a prospective observational study.

Buecking B, Eschbach D, Bliemel C, Oberkircher L, Struewer J, Ruchholtz S, Sachs UJ.

Thromb Res. 2014 Jan;133(1):42-7. doi: 10.1016/j.thromres.2013.10.031. Epub 2013 Oct 25.

PMID:
24196230
26.

External quality assessment in molecular immunohematology: the INSTAND proficiency test program.

Flegel WA, Chiosea I, Sachs UJ, Bein G.

Transfusion. 2013 Nov;53(11 Suppl 2):2850-8. doi: 10.1111/trf.12414. Epub 2013 Sep 20.

27.

Glycosylation of autoantibodies: insights into the mechanisms of immune thrombocytopenia.

Bakchoul T, Walek K, Krautwurst A, Rummel M, Bein G, Santoso S, Sachs UJ.

Thromb Haemost. 2013 Dec;110(6):1259-66. doi: 10.1160/TH13-04-0294. Epub 2013 Sep 26.

PMID:
24067937
28.

Anti-human neutrophil antigen-3a induced transfusion-related acute lung injury in mice by direct disturbance of lung endothelial cells.

Bayat B, Tjahjono Y, Sydykov A, Werth S, Hippenstiel S, Weissmann N, Sachs UJ, Santoso S.

Arterioscler Thromb Vasc Biol. 2013 Nov;33(11):2538-48. doi: 10.1161/ATVBAHA.113.301206. Epub 2013 Sep 5.

PMID:
24008160
29.

A single center comparison between three different apheresis systems for autologous and allogeneic stem cell collections.

Flommersfeld S, Bakchoul T, Bein G, Wachtel A, Loechelt C, Sachs UJ.

Transfus Apher Sci. 2013 Dec;49(3):428-33. doi: 10.1016/j.transci.2013.06.002. Epub 2013 Jul 1.

PMID:
23827328
30.

Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia.

Bakchoul T, Greinacher A, Sachs UJ, Krautwurst A, Renz H, Harb H, Bein G, Newman PJ, Santoso S.

Blood. 2013 Jul 18;122(3):321-7. doi: 10.1182/blood-2012-11-468561. Epub 2013 May 3.

31.

A highly specialised self-made computer program enhances efficiency and safety of immunohaematology reports.

Slonka J, Alrifai M, Bein G, Sachs UJ.

Transfus Med. 2013 Jun;23(3):207-14. doi: 10.1111/tme.12024. Epub 2013 Mar 21. No abstract available.

PMID:
23521661
32.

Fetal/neonatal alloimmune thrombocytopenia.

Sachs UJ.

Thromb Res. 2013 Jan;131 Suppl 1:S42-6. doi: 10.1016/S0049-3848(13)70020-3. Review.

PMID:
23452741
33.

Hemolytic transfusion reaction mimicked by occult retroperitoneal bleeding.

Flommersfeld S, Maisch B, Bein G, Sachs UJ.

Transfusion. 2013 Mar;53(3):482. doi: 10.1111/j.1537-2995.2012.03844.x. No abstract available.

PMID:
23473064
34.

Prevalence of hereditary antithrombin mutations is higher than estimated in patients with thrombotic events.

Fischer R, Sachs UJ, Heidinger KS, Eisenburger D, Kemkes-Matthes B.

Blood Coagul Fibrinolysis. 2013 Jun;24(4):444-8. doi: 10.1097/MBC.0b013e32835cc143.

PMID:
23429250
35.

HNA-1d: a new human neutrophil antigen located on Fcγ receptor IIIb associated with neonatal immune neutropenia.

Reil A, Sachs UJ, Siahanidou T, Flesch BK, Bux J.

Transfusion. 2013 Oct;53(10):2145-51. doi: 10.1111/trf.12086. Epub 2013 Jan 24.

PMID:
23347194
36.

Anti-protamine-heparin antibodies: incidence, clinical relevance, and pathogenesis.

Bakchoul T, Zöllner H, Amiral J, Panzer S, Selleng S, Kohlmann T, Brandt S, Delcea M, Warkentin TE, Sachs UJ, Greinacher A.

Blood. 2013 Apr 11;121(15):2821-7. doi: 10.1182/blood-2012-10-460691. Epub 2013 Jan 16.

37.

The implementation of surface plasmon resonance technique in monitoring pregnancies with expected fetal and neonatal alloimmune thrombocytopenia.

Bakchoul T, Bertrand G, Krautwurst A, Kroll H, Bein G, Sachs UJ, Santoso S, Kaplan C.

Transfusion. 2013 Sep;53(9):2078-85. doi: 10.1111/trf.12051. Epub 2012 Dec 24.

PMID:
23278334
38.

A threshold model for the susceptibility to transfusion-related acute lung injury.

Sachs UJ.

Transfus Clin Biol. 2012 Jun;19(3):109-16. doi: 10.1016/j.tracli.2012.03.003. Epub 2012 Jun 5. Review.

PMID:
22677431
39.

Transfusion-related acute lung injury: an overview.

Bayat B, Sachs UJ.

Curr Pharm Des. 2012;18(22):3236-40. Review.

PMID:
22621272
40.

Report on the 15th International Society of Blood Transfusion platelet immunology workshop.

Sachs UJ, Kiefel V, Kroll H, Bein G, Santoso S.

Vox Sang. 2012 Nov;103(4):343-51. doi: 10.1111/j.1423-0410.2012.01616.x. Epub 2012 May 16.

PMID:
22591461
41.

Rapid enzyme-linked immunosorbent assay for the detection of antibodies against human neutrophil antigens -1a, -1b, and -1c.

Werth S, Bayat B, Tjahjono Y, Eskandar J, Berghöfer H, Bein G, Sachs UJ, Santoso S.

Transfusion. 2013 Jan;53(1):193-201. doi: 10.1111/j.1537-2995.2012.03675.x. Epub 2012 May 3.

PMID:
22554254
42.

Frequency of heparin/platelet factor 4-dependent platelet antibodies in patients undergoing angioplasty and stenting for cardiovascular disease and their role for on-clopidogrel platelet reactivity.

Gremmel T, Frühwirth K, Kopp CW, Kaider A, Steiner S, Bakchoul T, Sachs UJ, Koppensteiner R, Panzer S.

Clin Res Cardiol. 2012 Jun;101(6):445-52. doi: 10.1007/s00392-011-0411-3. Epub 2012 Jan 11.

PMID:
22234620
43.

A point mutation in the EGF-4 domain of β(3) integrin is responsible for the formation of the Sec(a) platelet alloantigen and affects receptor function.

Sachs UJ, Bakchoul T, Eva O, Giptner A, Bein G, Aster RH, Gitter M, Peterson J, Santoso S.

Thromb Haemost. 2012 Jan;107(1):80-7. doi: 10.1160/TH11-08-0542. Epub 2011 Nov 24.

44.

Autoantibody-mediated complement activation on platelets is a common finding in patients with immune thrombocytopenic purpura (ITP).

Najaoui A, Bakchoul T, Stoy J, Bein G, Rummel MJ, Santoso S, Sachs UJ.

Eur J Haematol. 2012 Feb;88(2):167-74. doi: 10.1111/j.1600-0609.2011.01718.x. Epub 2011 Nov 22.

PMID:
21985182
45.

Evaluation of a new nanoparticle-based lateral-flow immunoassay for the exclusion of heparin-induced thrombocytopenia (HIT).

Sachs UJ, von Hesberg J, Santoso S, Bein G, Bakchoul T.

Thromb Haemost. 2011 Dec;106(6):1197-202. doi: 10.1160/TH-11-06-0390. Epub 2011 Oct 6.

PMID:
21979237
46.

Recent insights into the mechanism of transfusion-related acute lung injury.

Sachs UJ.

Curr Opin Hematol. 2011 Nov;18(6):436-42. doi: 10.1097/MOH.0b013e32834bab01. Review.

PMID:
21912251
47.

Prediction of fetal status in fetal/neonatal alloimmune thrombocytopenia (FNAIT)?

Sachs UJ, Bakchoul T, Kiefel V, Santoso S.

Blood. 2011 Sep 1;118(9):2637-8; author reply 2639-40. doi: 10.1182/blood-2011-06-359281. No abstract available.

48.

Implication of transfected cell lines for the detection of alloantibodies against human neutrophil antigen-3.

Bayat B, Tjahjono Y, Werth S, Berghöfer H, Reil A, Kroll H, Sachs UJ, Santoso S.

Transfusion. 2012 Mar;52(3):613-21. doi: 10.1111/j.1537-2995.2011.03303.x. Epub 2011 Aug 24.

PMID:
21883263
49.

Low-avidity anti-HPA-1a alloantibodies are capable of antigen-positive platelet destruction in the NOD/SCID mouse model of alloimmune thrombocytopenia.

Bakchoul T, Kubiak S, Krautwurst A, Roderfeld M, Siebert HC, Bein G, Sachs UJ, Santoso S.

Transfusion. 2011 Nov;51(11):2455-61. doi: 10.1111/j.1537-2995.2011.03171.x. Epub 2011 May 12.

PMID:
21564107
50.

Performance characteristics of two commercially available IgG-specific immunoassays in the assessment of heparin-induced thrombocytopenia (HIT).

Bakchoul T, Giptner A, Bein G, Santoso S, Sachs UJ.

Thromb Res. 2011 Apr;127(4):345-8. doi: 10.1016/j.thromres.2010.12.001. Epub 2011 Jan 12.

PMID:
21232785

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