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Items: 1 to 50 of 99

1.

Short-Term High-Flow Nasal Cannula for Moderate to Severe Bronchiolitis Is Effective in a General Pediatric Ward.

Sachs N, Rom E, Schonfeld T, Gavish R, Berger I, Krause I.

Clin Pediatr (Phila). 2019 Sep 26:9922819877881. doi: 10.1177/0009922819877881. [Epub ahead of print]

PMID:
31556700
2.

A Breath of Fresh Air: Outdoor Spaces in Healthcare Facilities Can Provide Clean Air and Respite.

Sachs NA.

HERD. 2019 Oct;12(4):226-230. doi: 10.1177/1937586719872396. No abstract available.

PMID:
31510889
3.

Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC.

Gamerdinger M, Kobayashi K, Wallisch A, Kreft SG, Sailer C, Schlömer R, Sachs N, Jomaa A, Stengel F, Ban N, Deuerling E.

Mol Cell. 2019 Sep 5;75(5):996-1006.e8. doi: 10.1016/j.molcel.2019.06.030. Epub 2019 Jul 31.

PMID:
31377116
4.

Evaluation of a Mental and Behavioral Health Patient Room Mockup at a VA Facility.

Sachs NA, Shepley MM, Peditto K, Hankinson MT, Smith K, Giebink B, Thompson T.

HERD. 2019 Jul 15:1937586719856349. doi: 10.1177/1937586719856349. [Epub ahead of print]

PMID:
31304785
5.

Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer.

Wang H, Xiang D, Liu B, He A, Randle HJ, Zhang KX, Dongre A, Sachs N, Clark AP, Tao L, Chen Q, Botchkarev VV Jr, Xie Y, Dai N, Clevers H, Li Z, Livingston DM.

Cell. 2019 Jun 27;178(1):135-151.e19. doi: 10.1016/j.cell.2019.06.002.

PMID:
31251913
6.

Jaynelle Stichler: A Modern Day Florence Nightingale.

Gregory D, Hamilton DK, Sachs NA.

HERD. 2019 Jul;12(3):8-10. doi: 10.1177/1937586719852805. Epub 2019 Jun 2. No abstract available.

PMID:
31154868
7.

Research on Nature in Healthcare: What Do We Still Need?

Sachs NA.

HERD. 2019 Apr;12(2):162-167. doi: 10.1177/1937586719848861. Epub 2019 May 14. No abstract available.

PMID:
31088174
8.

Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies.

Shen K, Gamerdinger M, Chan R, Gense K, Martin EM, Sachs N, Knight PD, Schlömer R, Calabrese AN, Stewart KL, Leiendecker L, Baghel A, Radford SE, Frydman J, Deuerling E.

Mol Cell. 2019 May 16;74(4):729-741.e7. doi: 10.1016/j.molcel.2019.03.012. Epub 2019 Apr 11.

9.

The effects of an alternative diet regimen with natural methionine ingredients on white striping breast myopathy in broiler chickens.

Sachs NJ, Hampton AR, Foster KK, Pechanec MY, Henderson JD, King AJ, Mienaltowski MJ.

Poult Sci. 2019 Jan 1;98(1):413-421. doi: 10.3382/ps/pey327.

PMID:
30690615
10.

Long-term expanding human airway organoids for disease modeling.

Sachs N, Papaspyropoulos A, Zomer-van Ommen DD, Heo I, Böttinger L, Klay D, Weeber F, Huelsz-Prince G, Iakobachvili N, Amatngalim GD, de Ligt J, van Hoeck A, Proost N, Viveen MC, Lyubimova A, Teeven L, Derakhshan S, Korving J, Begthel H, Dekkers JF, Kumawat K, Ramos E, van Oosterhout MF, Offerhaus GJ, Wiener DJ, Olimpio EP, Dijkstra KK, Smit EF, van der Linden M, Jaksani S, van de Ven M, Jonkers J, Rios AC, Voest EE, van Moorsel CH, van der Ent CK, Cuppen E, van Oudenaarden A, Coenjaerts FE, Meyaard L, Bont LJ, Peters PJ, Tans SJ, van Zon JS, Boj SF, Vries RG, Beekman JM, Clevers H.

EMBO J. 2019 Feb 15;38(4). pii: e100300. doi: 10.15252/embj.2018100300. Epub 2019 Jan 14.

11.

EBD at the Macro Level: How Research Informs Policy.

Sachs NA.

HERD. 2018 Oct;11(4):108-110. doi: 10.1177/1937586718812120. No abstract available.

PMID:
30411642
12.

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.

Dijkstra KK, Cattaneo CM, Weeber F, Chalabi M, van de Haar J, Fanchi LF, Slagter M, van der Velden DL, Kaing S, Kelderman S, van Rooij N, van Leerdam ME, Depla A, Smit EF, Hartemink KJ, de Groot R, Wolkers MC, Sachs N, Snaebjornsson P, Monkhorst K, Haanen J, Clevers H, Schumacher TN, Voest EE.

Cell. 2018 Sep 6;174(6):1586-1598.e12. doi: 10.1016/j.cell.2018.07.009. Epub 2018 Aug 9.

13.

Designing for Public Health With Healthcare Design Part II: Design.

Sachs NA.

HERD. 2018 Jul;11(3):17-21. doi: 10.1177/1937586718789033. No abstract available.

PMID:
30096046
14.

Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures.

Hui KPY, Ching RHH, Chan SKH, Nicholls JM, Sachs N, Clevers H, Peiris JSM, Chan MCW.

Lancet Respir Med. 2018 Nov;6(11):846-854. doi: 10.1016/S2213-2600(18)30236-4. Epub 2018 Jul 11.

PMID:
30001996
15.

Modelling Cryptosporidium infection in human small intestinal and lung organoids.

Heo I, Dutta D, Schaefer DA, Iakobachvili N, Artegiani B, Sachs N, Boonekamp KE, Bowden G, Hendrickx APA, Willems RJL, Peters PJ, Riggs MW, O'Connor R, Clevers H.

Nat Microbiol. 2018 Jul;3(7):814-823. doi: 10.1038/s41564-018-0177-8. Epub 2018 Jun 25.

16.

Differentiated human airway organoids to assess infectivity of emerging influenza virus.

Zhou J, Li C, Sachs N, Chiu MC, Wong BH, Chu H, Poon VK, Wang D, Zhao X, Wen L, Song W, Yuan S, Wong KK, Chan JF, To KK, Chen H, Clevers H, Yuen KY.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6822-6827. doi: 10.1073/pnas.1806308115. Epub 2018 Jun 11.

17.

Enterovirus 71 infection of human airway organoids reveals VP1-145 as a viral infectivity determinant.

van der Sanden SMG, Sachs N, Koekkoek SM, Koen G, Pajkrt D, Clevers H, Wolthers KC.

Emerg Microbes Infect. 2018 May 9;7(1):84. doi: 10.1038/s41426-018-0077-2.

18.

Designing for Public Health With Healthcare Design, Part I: Research.

Sachs NA.

HERD. 2018 Apr;11(2):13-15. doi: 10.1177/1937586718774114. Epub 2018 May 2. No abstract available.

PMID:
29719994
19.

Beyond Responsivity: Client Service Engagement in a Reentry Demonstration Program.

Sachs NM, Miller J.

Int J Offender Ther Comp Criminol. 2018 Oct;62(13):4295-4313. doi: 10.1177/0306624X18763762. Epub 2018 Mar 19.

PMID:
29552911
20.

Here's Some Great Research! Now What? Translating Research Into Practice.

Sachs NA.

HERD. 2018 Jan;11(1):40-42. doi: 10.1177/1937586718757309. Epub 2018 Feb 15. No abstract available.

PMID:
29448835
21.

Implicit Social Cognitive Processes Underlying Victim Self and Identity: Evidence With College-Aged Adults.

Sachs NM, Veysey BM, Rivera LM.

J Interpers Violence. 2017 Nov 1:886260517741625. doi: 10.1177/0886260517741625. [Epub ahead of print]

PMID:
29294984
22.

BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance.

Duarte AA, Gogola E, Sachs N, Barazas M, Annunziato S, R de Ruiter J, Velds A, Blatter S, Houthuijzen JM, van de Ven M, Clevers H, Borst P, Jonkers J, Rottenberg S.

Nat Methods. 2018 Feb;15(2):134-140. doi: 10.1038/nmeth.4535. Epub 2017 Dec 11.

PMID:
29256493
23.

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity.

Sachs N, de Ligt J, Kopper O, Gogola E, Bounova G, Weeber F, Balgobind AV, Wind K, Gracanin A, Begthel H, Korving J, van Boxtel R, Duarte AA, Lelieveld D, van Hoeck A, Ernst RF, Blokzijl F, Nijman IJ, Hoogstraat M, van de Ven M, Egan DA, Zinzalla V, Moll J, Boj SF, Voest EE, Wessels L, van Diest PJ, Rottenberg S, Vries RGJ, Cuppen E, Clevers H.

Cell. 2018 Jan 11;172(1-2):373-386.e10. doi: 10.1016/j.cell.2017.11.010. Epub 2017 Dec 7.

24.

The Case for Nature or Nature-ish.

Sachs NA.

HERD. 2017 Oct;10(5):157-161. doi: 10.1177/1937586717732653. No abstract available.

PMID:
29056091
25.

Chronic Q Fever Infections in Israeli Children: A 25-year Nationwide Study.

Sachs N, Atiya-Nasagi Y, Beth-Din A, Levy I, Ben-Shimol S, Tasher D, Grisaru-Soen G, Dabaja H, Kassis I, Spilman S, Bilavsky E.

Pediatr Infect Dis J. 2018 Mar;37(3):212-217. doi: 10.1097/INF.0000000000001790.

PMID:
28938256
26.

The Next Chapter: Co-Editor #3.

Sachs NA.

HERD. 2017 Jul;10(4):7-9. doi: 10.1177/1937586717711497. No abstract available.

PMID:
28643561
27.

Intestinal epithelial organoids fuse to form self-organizing tubes in floating collagen gels.

Sachs N, Tsukamoto Y, Kujala P, Peters PJ, Clevers H.

Development. 2017 Mar 15;144(6):1107-1112. doi: 10.1242/dev.143933.

28.

Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering?

Schneeberger K, Spee B, Costa P, Sachs N, Clevers H, Malda J.

Biofabrication. 2017 Mar 6;9(1):013001. doi: 10.1088/1758-5090/aa6121. Review.

PMID:
28211365
29.

The Antituberculosis Drug Ethambutol Selectively Blocks Apical Growth in CMN Group Bacteria.

Schubert K, Sieger B, Meyer F, Giacomelli G, Böhm K, Rieblinger A, Lindenthal L, Sachs N, Wanner G, Bramkamp M.

MBio. 2017 Feb 7;8(1). pii: e02213-16. doi: 10.1128/mBio.02213-16.

30.

Designer matrices for intestinal stem cell and organoid culture.

Gjorevski N, Sachs N, Manfrin A, Giger S, Bragina ME, Ordóñez-Morán P, Clevers H, Lutolf MP.

Nature. 2016 Nov 24;539(7630):560-564. doi: 10.1038/nature20168. Epub 2016 Nov 16.

PMID:
27851739
31.

Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon.

Sasaki N, Sachs N, Wiebrands K, Ellenbroek SI, Fumagalli A, Lyubimova A, Begthel H, van den Born M, van Es JH, Karthaus WR, Li VS, López-Iglesias C, Peters PJ, van Rheenen J, van Oudenaarden A, Clevers H.

Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5399-407. doi: 10.1073/pnas.1607327113. Epub 2016 Aug 29.

32.

Synthesis and optimization of N-heterocyclic pyridinones as catechol-O-methyltransferase (COMT) inhibitors.

Zhao Z, Harrison ST, Schubert JW, Sanders JM, Polsky-Fisher S, Zhang NR, McLoughlin D, Gibson CR, Robinson RG, Sachs NA, Kandebo M, Yao L, Smith SM, Hutson PH, Wolkenberg SE, Barrow JC.

Bioorg Med Chem Lett. 2016 Jun 15;26(12):2952-2956. doi: 10.1016/j.bmcl.2016.03.095. Epub 2016 Apr 7.

PMID:
27133481
33.

Doravirine Suppresses Common Nonnucleoside Reverse Transcriptase Inhibitor-Associated Mutants at Clinically Relevant Concentrations.

Feng M, Sachs NA, Xu M, Grobler J, Blair W, Hazuda DJ, Miller MD, Lai MT.

Antimicrob Agents Chemother. 2016 Mar 25;60(4):2241-7. doi: 10.1128/AAC.02650-15. Print 2016 Apr.

34.

Brain-state classification and a dual-state decoder dramatically improve the control of cursor movement through a brain-machine interface.

Sachs NA, Ruiz-Torres R, Perreault EJ, Miller LE.

J Neural Eng. 2016 Feb;13(1):016009. doi: 10.1088/1741-2560/13/1/016009. Epub 2015 Dec 11.

35.

Rkr1/Ltn1 Ubiquitin Ligase-mediated Degradation of Translationally Stalled Endoplasmic Reticulum Proteins.

Crowder JJ, Geigges M, Gibson RT, Fults ES, Buchanan BW, Sachs N, Schink A, Kreft SG, Rubenstein EM.

J Biol Chem. 2015 Jul 24;290(30):18454-66. doi: 10.1074/jbc.M115.663559. Epub 2015 Jun 8.

36.

Sequential cancer mutations in cultured human intestinal stem cells.

Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H.

Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29.

PMID:
25924068
37.

Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).

Harrison ST, Poslusney MS, Mulhearn JJ, Zhao Z, Kett NR, Schubert JW, Melamed JY, Allison TJ, Patel SB, Sanders JM, Sharma S, Smith RF, Hall DL, Robinson RG, Sachs NA, Hutson PH, Wolkenberg SE, Barrow JC.

ACS Med Chem Lett. 2015 Jan 26;6(3):318-23. doi: 10.1021/ml500502d. eCollection 2015 Mar 12.

38.

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.

Karthaus WR, Iaquinta PJ, Drost J, Gracanin A, van Boxtel R, Wongvipat J, Dowling CM, Gao D, Begthel H, Sachs N, Vries RGJ, Cuppen E, Chen Y, Sawyers CL, Clevers HC.

Cell. 2014 Sep 25;159(1):163-175. doi: 10.1016/j.cell.2014.08.017. Epub 2014 Sep 4.

39.

Multimodal decoding and congruent sensory information enhance reaching performance in subjects with cervical spinal cord injury.

Corbett EA, Sachs NA, Körding KP, Perreault EJ.

Front Neurosci. 2014 May 23;8:123. doi: 10.3389/fnins.2014.00123. eCollection 2014.

40.

Australian Healthcare Design 2000-2015: A critical review of the design and build of infrastructure in Australia.

Sachs NA, Shepley MM.

HERD. Spring 2014;7(3):152-4. No abstract available.

PMID:
24782242
41.

Organoid cultures for the analysis of cancer phenotypes.

Sachs N, Clevers H.

Curr Opin Genet Dev. 2014 Feb;24:68-73. doi: 10.1016/j.gde.2013.11.012. Epub 2013 Dec 31. Review.

PMID:
24657539
42.

In vitro characterization of MK-1439, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor.

Lai MT, Feng M, Falgueyret JP, Tawa P, Witmer M, DiStefano D, Li Y, Burch J, Sachs N, Lu M, Cauchon E, Campeau LC, Grobler J, Yan Y, Ducharme Y, Côté B, Asante-Appiah E, Hazuda DJ, Miller MD.

Antimicrob Agents Chemother. 2014;58(3):1652-63. doi: 10.1128/AAC.02403-13. Epub 2013 Dec 30.

43.

Reduced susceptibility to two-stage skin carcinogenesis in mice with epidermis-specific deletion of CD151.

Sachs N, Secades P, van Hulst L, Song JY, Sonnenberg A.

J Invest Dermatol. 2014 Jan;134(1):221-228. doi: 10.1038/jid.2013.280. Epub 2013 Jun 21.

44.

Benzalkonium chloride-induced denervation of orbicularis oculi muscle in rabbits.

Francis BA, Weiland JD, Sachs NA, Chang EL.

Invest Ophthalmol Vis Sci. 2013 Mar 13;54(3):1868-72. doi: 10.1167/iovs.12-10792.

PMID:
23425696
45.

Cell-matrix adhesion of podocytes in physiology and disease.

Sachs N, Sonnenberg A.

Nat Rev Nephrol. 2013 Apr;9(4):200-10. doi: 10.1038/nrneph.2012.291. Epub 2013 Jan 22. Review.

PMID:
23338211
46.

Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.

Sachs N, Secades P, van Hulst L, Kreft M, Song JY, Sonnenberg A.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21468-73. doi: 10.1073/pnas.1204614110. Epub 2012 Dec 10.

47.

Functional connectivity and tuning curves in populations of simultaneously recorded neurons.

Stevenson IH, London BM, Oby ER, Sachs NA, Reimer J, Englitz B, David SV, Shamma SA, Blanche TJ, Mizuseki K, Zandvakili A, Hatsopoulos NG, Miller LE, Kording KP.

PLoS Comput Biol. 2012;8(11):e1002775. doi: 10.1371/journal.pcbi.1002775. Epub 2012 Nov 15.

48.

Gain of glycosylation in integrin α3 causes lung disease and nephrotic syndrome.

Nicolaou N, Margadant C, Kevelam SH, Lilien MR, Oosterveld MJ, Kreft M, van Eerde AM, Pfundt R, Terhal PA, van der Zwaag B, Nikkels PG, Sachs N, Goldschmeding R, Knoers NV, Renkema KY, Sonnenberg A.

J Clin Invest. 2012 Dec;122(12):4375-87. doi: 10.1172/JCI64100. Epub 2012 Nov 1.

49.

Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substrates.

Robinson RG, Smith SM, Wolkenberg SE, Kandebo M, Yao L, Gibson CR, Harrison ST, Polsky-Fisher S, Barrow JC, Manley PJ, Mulhearn JJ, Nanda KK, Schubert JW, Trotter BW, Zhao Z, Sanders JM, Smith RF, McLoughlin D, Sharma S, Hall DL, Walker TL, Kershner JL, Bhandari N, Hutson PH, Sachs NA.

ACS Chem Neurosci. 2012 Feb 15;3(2):129-40. doi: 10.1021/cn200109w. Epub 2011 Nov 14.

50.

On the biomechanics of stem cell niche formation in the gut--modelling growing organoids.

Buske P, Przybilla J, Loeffler M, Sachs N, Sato T, Clevers H, Galle J.

FEBS J. 2012 Sep;279(18):3475-87. doi: 10.1111/j.1742-4658.2012.08646.x. Epub 2012 Jun 18.

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