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Items: 1 to 50 of 127

1.

PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.

Steinbach N, Hasson D, Mathur D, Stratikopoulos EE, Sachidanandam R, Bernstein E, Parsons RE.

Nucleic Acids Res. 2019 Jun 20;47(11):5573-5586. doi: 10.1093/nar/gkz272.

2.

Next Generation Sequencing of the Pig αβ TCR Repertoire Identifies the Porcine Invariant NKT Cell Receptor.

Yang G, Artiaga BL, Lomelino CL, Jayaprakash AD, Sachidanandam R, Mckenna R, Driver JP.

J Immunol. 2019 Apr 1;202(7):1981-1991. doi: 10.4049/jimmunol.1801171. Epub 2019 Feb 18.

PMID:
30777925
3.

Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade.

Pai CS, Huang JT, Lu X, Simons DM, Park C, Chang A, Tamaki W, Liu E, Roybal KT, Seagal J, Chen M, Hagihara K, Wei XX, DuPage M, Kwek SS, Oh DY, Daud A, Tsai KK, Wu C, Zhang L, Fasso M, Sachidanandam R, Jayaprakash A, Lin I, Casbon AJ, Kinsbury GA, Fong L.

Immunity. 2019 Feb 19;50(2):477-492.e8. doi: 10.1016/j.immuni.2019.01.006. Epub 2019 Feb 5.

PMID:
30737146
4.

Comparison between broadband and monochromatic photopic negative response in full-field electroretinogram in controls and subjects with primary open-angle glaucoma.

Banerjee A, Khurana M, Sachidanandam R, Sen P.

Doc Ophthalmol. 2019 Feb;138(1):21-33. doi: 10.1007/s10633-018-09668-1. Epub 2019 Jan 12.

PMID:
30635745
5.

SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-Dependent Tumors.

Ahmed TA, Adamopoulos C, Karoulia Z, Wu X, Sachidanandam R, Aaronson SA, Poulikakos PI.

Cell Rep. 2019 Jan 2;26(1):65-78.e5. doi: 10.1016/j.celrep.2018.12.013.

6.

Exonuclease Domain-Containing 1 Enhances MIWI2 piRNA Biogenesis via Its Interaction with TDRD12.

Pandey RR, Homolka D, Olotu O, Sachidanandam R, Kotaja N, Pillai RS.

Cell Rep. 2018 Sep 25;24(13):3423-3432.e4. doi: 10.1016/j.celrep.2018.08.087.

7.

Unperturbed expression bias of imprinted genes in schizophrenia.

Gulyás-Kovács A, Keydar I, Xia E, Fromer M, Hoffman G, Ruderfer D, Sachidanandam R, Chess A.

Nat Commun. 2018 Jul 25;9(1):2914. doi: 10.1038/s41467-018-04960-9.

8.

Swept-source optical coherence tomography study of choroidal morphology in Stargardt disease.

Ratra D, Jaishankar D, Sachidanandam R, Yusufali H, Ratra V.

Oman J Ophthalmol. 2018 May-Aug;11(2):150-157. doi: 10.4103/ojo.OJO_21_2017.

9.

Diet Modifies Colonic Microbiota and CD4+ T-Cell Repertoire to Induce Flares of Colitis in Mice With Myeloid-Cell Expression of Interleukin 23.

Chen L, He Z, Iuga AC, Martins Filho SN, Faith JJ, Clemente JC, Deshpande M, Jayaprakash A, Colombel JF, Lafaille JJ, Sachidanandam R, Furtado GC, Lira SA.

Gastroenterology. 2018 Oct;155(4):1177-1191.e16. doi: 10.1053/j.gastro.2018.06.034. Epub 2018 Jun 15.

PMID:
29909020
10.

Understanding variable disease severity in X-linked retinoschisis: Does RS1 secretory mechanism determine disease severity?

Sudha D, Neriyanuri S, Sachidanandam R, Natarajan SN, Gandra M, Tharigopala A, Sivashanmugam M, Alameen M, Vetrivel U, Gopal L, Khetan V, Raman R, Sen P, Chidambaram S, Arunachalam JP.

PLoS One. 2018 May 31;13(5):e0198086. doi: 10.1371/journal.pone.0198086. eCollection 2018.

11.

Quiescent Tissue Stem Cells Evade Immune Surveillance.

Agudo J, Park ES, Rose SA, Alibo E, Sweeney R, Dhainaut M, Kobayashi KS, Sachidanandam R, Baccarini A, Merad M, Brown BD.

Immunity. 2018 Feb 20;48(2):271-285.e5. doi: 10.1016/j.immuni.2018.02.001.

12.

Regulation of m6A Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline.

Wojtas MN, Pandey RR, Mendel M, Homolka D, Sachidanandam R, Pillai RS.

Mol Cell. 2017 Oct 19;68(2):374-387.e12. doi: 10.1016/j.molcel.2017.09.021. Epub 2017 Oct 12.

13.

Recruitment of Armitage and Yb to a transcript triggers its phased processing into primary piRNAs in Drosophila ovaries.

Pandey RR, Homolka D, Chen KM, Sachidanandam R, Fauvarque MO, Pillai RS.

PLoS Genet. 2017 Aug 21;13(8):e1006956. doi: 10.1371/journal.pgen.1006956. eCollection 2017 Aug.

14.

Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation.

Touat-Todeschini L, Shichino Y, Dangin M, Thierry-Mieg N, Gilquin B, Hiriart E, Sachidanandam R, Lambert E, Brettschneider J, Reuter M, Kadlec J, Pillai R, Yamashita A, Yamamoto M, Verdel A.

EMBO J. 2017 Sep 1;36(17):2626-2641. doi: 10.15252/embj.201796571. Epub 2017 Aug 1.

15.

MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect.

Shtraizent N, DeRossi C, Nayar S, Sachidanandam R, Katz LS, Prince A, Koh AP, Vincek A, Hadas Y, Hoshida Y, Scott DK, Eliyahu E, Freeze HH, Sadler KC, Chu J.

Elife. 2017 Jun 23;6. pii: e22477. doi: 10.7554/eLife.22477.

16.

Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI Slicing-Triggered Mammalian piRNA Biogenesis and Function.

Wenda JM, Homolka D, Yang Z, Spinelli P, Sachidanandam R, Pandey RR, Pillai RS.

Dev Cell. 2017 Jun 19;41(6):623-637.e9. doi: 10.1016/j.devcel.2017.05.021.

17.

Effect of axial length on full-field and multifocal electroretinograms.

Sachidanandam R, Ravi P, Sen P.

Clin Exp Optom. 2017 Nov;100(6):668-675. doi: 10.1111/cxo.12529. Epub 2017 Mar 7.

PMID:
28266057
18.

Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability.

Gillinder KR, Ilsley MD, Nébor D, Sachidanandam R, Lajoie M, Magor GW, Tallack MR, Bailey T, Landsberg MJ, Mackay JP, Parker MW, Miles LA, Graber JH, Peters LL, Bieker JJ, Perkins AC.

Nucleic Acids Res. 2017 Feb 17;45(3):1130-1143. doi: 10.1093/nar/gkw1014.

19.

Innate Immune Responses of Bat and Human Cells to Filoviruses: Commonalities and Distinctions.

Kuzmin IV, Schwarz TM, Ilinykh PA, Jordan I, Ksiazek TG, Sachidanandam R, Basler CF, Bukreyev A.

J Virol. 2017 Mar 29;91(8). pii: e02471-16. doi: 10.1128/JVI.02471-16. Print 2017 Apr 15.

20.

Reduced-fluence photodynamic therapy and anti-vascular endothelial growth factor for polypoidal choroidal vasculopathy in an Indian population.

Sen P, Bhende M, Sachidanandam R, Bansal N, Sharma T.

Indian J Ophthalmol. 2016 Dec;64(12):908-913. doi: 10.4103/0301-4738.198856.

21.

CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations.

Guernet A, Mungamuri SK, Cartier D, Sachidanandam R, Jayaprakash A, Adriouch S, Vezain M, Charbonnier F, Rohkin G, Coutant S, Yao S, Ainani H, Alexandre D, Tournier I, Boyer O, Aaronson SA, Anouar Y, Grumolato L.

Mol Cell. 2016 Aug 4;63(3):526-38. doi: 10.1016/j.molcel.2016.06.017. Epub 2016 Jul 21.

22.

Isolation and Characterization of a Novel Gammaherpesvirus from a Microbat Cell Line.

Shabman RS, Shrivastava S, Tsibane T, Attie O, Jayaprakash A, Mire CE, Dilley KE, Puri V, Stockwell TB, Geisbert TW, Sachidanandam R, Basler CF.

mSphere. 2016 Feb 17;1(1). pii: e00070-15. doi: 10.1128/mSphere.00070-15. eCollection 2016 Jan-Feb.

23.

Next-generation sequencing confirms the implication of SLC24A1 in autosomal-recessive congenital stationary night blindness.

Neuillé M, Malaichamy S, Vadalà M, Michiels C, Condroyer C, Sachidanandam R, Srilekha S, Arokiasamy T, Letexier M, Démontant V, Sahel JA, Sen P, Audo I, Soumittra N, Zeitz C.

Clin Genet. 2016 Jun;89(6):690-9. doi: 10.1111/cge.12746. Epub 2016 Mar 4.

PMID:
26822852
24.

PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway.

Yang Z, Chen KM, Pandey RR, Homolka D, Reuter M, Janeiro BK, Sachidanandam R, Fauvarque MO, McCarthy AA, Pillai RS.

Mol Cell. 2016 Jan 7;61(1):138-52. doi: 10.1016/j.molcel.2015.11.009. Epub 2015 Dec 6.

25.

Deep sequencing of mRNA in CD24(-) and CD24(+) mammary carcinoma Mvt1 cell line.

Rostoker R, Jayaprakash AD, Sachidanandam R, LeRoith D.

Genom Data. 2015 Jul 9;5:399-401. doi: 10.1016/j.gdata.2015.06.032. eCollection 2015 Sep.

26.

piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire.

Senti KA, Jurczak D, Sachidanandam R, Brennecke J.

Genes Dev. 2015 Aug 15;29(16):1747-62. doi: 10.1101/gad.267252.115.

27.

MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation.

Manakov SA, Pezic D, Marinov GK, Pastor WA, Sachidanandam R, Aravin AA.

Cell Rep. 2015 Aug 25;12(8):1234-43. doi: 10.1016/j.celrep.2015.07.036. Epub 2015 Aug 13.

28.

Expression of an estrogen-regulated variant transcript of the peroxisomal branched chain fatty acid oxidase ACOX2 in breast carcinomas.

Bjørklund SS, Kristensen VN, Seiler M, Kumar S, Alnæs GI, Ming Y, Kerrigan J, Naume B, Sachidanandam R, Bhanot G, Børresen-Dale AL, Ganesan S.

BMC Cancer. 2015 Jul 17;15:524. doi: 10.1186/s12885-015-1510-8.

29.

PIWI Slicing and RNA Elements in Precursors Instruct Directional Primary piRNA Biogenesis.

Homolka D, Pandey RR, Goriaux C, Brasset E, Vaury C, Sachidanandam R, Fauvarque MO, Pillai RS.

Cell Rep. 2015 Jul 21;12(3):418-28. doi: 10.1016/j.celrep.2015.06.030. Epub 2015 Jul 9.

30.

CD24(+) cells fuel rapid tumor growth and display high metastatic capacity.

Rostoker R, Abelson S, Genkin I, Ben-Shmuel S, Sachidanandam R, Scheinman EJ, Bitton-Worms K, Orr ZS, Caspi A, Tzukerman M, LeRoith D.

Breast Cancer Res. 2015 Jun 4;17:78. doi: 10.1186/s13058-015-0589-9.

31.

Comparison between fullfield electroretinography obtained from handheld and tabletop devices in normal subjects.

Sachidanandam R, Khetan V, Sen P.

Can J Ophthalmol. 2015 Apr;50(2):166-71. doi: 10.1016/j.jcjo.2014.11.002.

PMID:
25863859
32.

Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA.

Jayaprakash AD, Benson EK, Gone S, Liang R, Shim J, Lambertini L, Toloue MM, Wigler M, Aaronson SA, Sachidanandam R.

Nucleic Acids Res. 2015 Feb 27;43(4):2177-87. doi: 10.1093/nar/gkv052. Epub 2015 Feb 4.

33.

Draft Genome Sequence of Bacillus alcalophilus AV1934, a Classic Alkaliphile Isolated from Human Feces in 1934.

Attie O, Jayaprakash A, Shah H, Paulsen IT, Morino M, Takahashi Y, Narumi I, Sachidanandam R, Satoh K, Ito M, Krulwich TA.

Genome Announc. 2014 Nov 13;2(6). pii: e01175-14. doi: 10.1128/genomeA.01175-14.

34.

The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript.

Malone CD, Mestdagh C, Akhtar J, Kreim N, Deinhard P, Sachidanandam R, Treisman J, Roignant JY.

Genes Dev. 2014 Aug 15;28(16):1786-99. doi: 10.1101/gad.245829.114. Epub 2014 Aug 7.

35.

Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing.

Le Thomas A, Stuwe E, Li S, Du J, Marinov G, Rozhkov N, Chen YC, Luo Y, Sachidanandam R, Toth KF, Patel D, Aravin AA.

Genes Dev. 2014 Aug 1;28(15):1667-80. doi: 10.1101/gad.245514.114.

36.

mRNA-Seq reveals novel molecular mechanisms and a robust fingerprint in Graves' disease.

Yin X, Sachidanandam R, Morshed S, Latif R, Shi R, Davies TF.

J Clin Endocrinol Metab. 2014 Oct;99(10):E2076-83. doi: 10.1210/jc.2014-1735. Epub 2014 Jun 27.

37.

piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells.

Pezic D, Manakov SA, Sachidanandam R, Aravin AA.

Genes Dev. 2014 Jul 1;28(13):1410-28. doi: 10.1101/gad.240895.114. Epub 2014 Jun 17.

38.

RNA clamping by Vasa assembles a piRNA amplifier complex on transposon transcripts.

Xiol J, Spinelli P, Laussmann MA, Homolka D, Yang Z, Cora E, Couté Y, Conn S, Kadlec J, Sachidanandam R, Kaksonen M, Cusack S, Ephrussi A, Pillai RS.

Cell. 2014 Jun 19;157(7):1698-711. doi: 10.1016/j.cell.2014.05.018. Epub 2014 Jun 5.

39.

Activating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafish.

Howarth DL, Lindtner C, Vacaru AM, Sachidanandam R, Tsedensodnom O, Vasilkova T, Buettner C, Sadler KC.

PLoS Genet. 2014 May 29;10(5):e1004335. doi: 10.1371/journal.pgen.1004335. eCollection 2014.

40.

The MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs.

Cora E, Pandey RR, Xiol J, Taylor J, Sachidanandam R, McCarthy AA, Pillai RS.

RNA. 2014 Jun;20(6):773-81. doi: 10.1261/rna.044701.114. Epub 2014 Apr 22.

41.

Molecular profiling of complete congenital stationary night blindness: a pilot study on an Indian cohort.

Malaichamy S, Sen P, Sachidanandam R, Arokiasamy T, Lancelot ME, Audo I, Zeitz C, Soumittra N.

Mol Vis. 2014 Mar 21;20:341-51. eCollection 2014. Erratum in: Mol Vis. 2014;20:780.

42.

Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape.

Cecere G, Hoersch S, O'Keeffe S, Sachidanandam R, Grishok A.

Nat Struct Mol Biol. 2014 Apr;21(4):358-65. doi: 10.1038/nsmb.2801. Epub 2014 Mar 30.

43.

UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma.

Mudbhary R, Hoshida Y, Chernyavskaya Y, Jacob V, Villanueva A, Fiel MI, Chen X, Kojima K, Thung S, Bronson RT, Lachenmayer A, Revill K, Alsinet C, Sachidanandam R, Desai A, SenBanerjee S, Ukomadu C, Llovet JM, Sadler KC.

Cancer Cell. 2014 Feb 10;25(2):196-209. doi: 10.1016/j.ccr.2014.01.003. Epub 2014 Jan 30.

44.

Multifaceted roles of miR-1s in repressing the fetal gene program in the heart.

Wei Y, Peng S, Wu M, Sachidanandam R, Tu Z, Zhang S, Falce C, Sobie EA, Lebeche D, Zhao Y.

Cell Res. 2014 Mar;24(3):278-92. doi: 10.1038/cr.2014.12. Epub 2014 Jan 31.

45.

p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes.

Benson EK, Mungamuri SK, Attie O, Kracikova M, Sachidanandam R, Manfredi JJ, Aaronson SA.

Oncogene. 2014 Jul 24;33(30):3959-69. doi: 10.1038/onc.2013.378. Epub 2013 Oct 7.

46.

Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.

Pandey RR, Tokuzawa Y, Yang Z, Hayashi E, Ichisaka T, Kajita S, Asano Y, Kunieda T, Sachidanandam R, Chuma S, Yamanaka S, Pillai RS.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16492-7. doi: 10.1073/pnas.1316316110. Epub 2013 Sep 25.

47.

Bacterial argonaute samples the transcriptome to identify foreign DNA.

Olovnikov I, Chan K, Sachidanandam R, Newman DK, Aravin AA.

Mol Cell. 2013 Sep 12;51(5):594-605. doi: 10.1016/j.molcel.2013.08.014.

48.

An in vivo RNAi screening approach to identify host determinants of virus replication.

Varble A, Benitez AA, Schmid S, Sachs D, Shim JV, Rodriguez-Barrueco R, Panis M, Crumiller M, Silva JM, Sachidanandam R, tenOever BR.

Cell Host Microbe. 2013 Sep 11;14(3):346-56. doi: 10.1016/j.chom.2013.08.007.

49.

MiST: a new approach to variant detection in deep sequencing datasets.

Subramanian S, Di Pierro V, Shah H, Jayaprakash AD, Weisberger I, Shim J, George A, Gelb BD, Sachidanandam R.

Nucleic Acids Res. 2013 Sep;41(16):e154. doi: 10.1093/nar/gkt551. Epub 2013 Jul 4.

50.

De novo mutations in histone-modifying genes in congenital heart disease.

Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton JD, Romano-Adesman A, Bjornson RD, Breitbart RE, Brown KK, Carriero NJ, Cheung YH, Deanfield J, DePalma S, Fakhro KA, Glessner J, Hakonarson H, Italia MJ, Kaltman JR, Kaski J, Kim R, Kline JK, Lee T, Leipzig J, Lopez A, Mane SM, Mitchell LE, Newburger JW, Parfenov M, Pe'er I, Porter G, Roberts AE, Sachidanandam R, Sanders SJ, Seiden HS, State MW, Subramanian S, Tikhonova IR, Wang W, Warburton D, White PS, Williams IA, Zhao H, Seidman JG, Brueckner M, Chung WK, Gelb BD, Goldmuntz E, Seidman CE, Lifton RP.

Nature. 2013 Jun 13;498(7453):220-3. doi: 10.1038/nature12141. Epub 2013 May 12.

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