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Items: 1 to 50 of 57

1.

Whole-Brain Vasculature Reconstruction at the Single Capillary Level.

Di Giovanna AP, Tibo A, Silvestri L, Müllenbroich MC, Costantini I, Allegra Mascaro AL, Sacconi L, Frasconi P, Pavone FS.

Sci Rep. 2018 Aug 22;8(1):12573. doi: 10.1038/s41598-018-30533-3.

2.

Real-time optical manipulation of cardiac conduction in intact hearts.

Scardigli M, Müllenbroich C, Margoni E, Cannazzaro S, Crocini C, Ferrantini C, Coppini R, Yan P, Loew LM, Campione M, Bocchi L, Giulietti D, Cerbai E, Poggesi C, Bub G, Pavone FS, Sacconi L.

J Physiol. 2018 Sep;596(17):3841-3858. doi: 10.1113/JP276283. Epub 2018 Aug 7.

3.

Confocal multispot microscope for fast and deep imaging in semicleared tissues.

Adam MP, Müllenbroich MC, Di Giovanna AP, Alfieri D, Silvestri L, Sacconi L, Pavone FS.

J Biomed Opt. 2018 Feb;23(2):1-4. doi: 10.1117/1.JBO.23.2.020503.

PMID:
29460510
4.

Reply to Entcheva: The impact of T-tubules on action potential propagation in cardiac tissue.

Scardigli M, Crocini C, Ferrantini C, Gabbrielli T, Silvestri L, Coppini R, Tesi C, Rog-Zielinska EA, Kohl P, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E562-E563. doi: 10.1073/pnas.1720253115. Epub 2018 Jan 5. No abstract available.

5.
6.

Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair.

Martella D, Paoli P, Pioner JM, Sacconi L, Coppini R, Santini L, Lulli M, Cerbai E, Wiersma DS, Poggesi C, Ferrantini C, Parmeggiani C.

Small. 2017 Dec;13(46). doi: 10.1002/smll.201702677. Epub 2017 Oct 17.

PMID:
29045016
7.

Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.

Ferrantini C, Coppini R, Pioner JM, Gentile F, Tosi B, Mazzoni L, Scellini B, Piroddi N, Laurino A, Santini L, Spinelli V, Sacconi L, De Tombe P, Moore R, Tardiff J, Mugelli A, Olivotto I, Cerbai E, Tesi C, Poggesi C.

J Am Heart Assoc. 2017 Jul 22;6(7). pii: e005407. doi: 10.1161/JAHA.116.005407.

8.

Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy.

Scardigli M, Crocini C, Ferrantini C, Gabbrielli T, Silvestri L, Coppini R, Tesi C, Rog-Zielinska EA, Kohl P, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):5737-5742. doi: 10.1073/pnas.1702188114. Epub 2017 May 15.

9.

Optogenetics gets to the heart: A guiding light beyond defibrillation.

Crocini C, Ferrantini C, Pavone FS, Sacconi L.

Prog Biophys Mol Biol. 2017 Nov;130(Pt B):132-139. doi: 10.1016/j.pbiomolbio.2017.05.002. Epub 2017 May 12. Review.

PMID:
28506694
10.

Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy.

Coppini R, Mazzoni L, Ferrantini C, Gentile F, Pioner JM, Laurino A, Santini L, Bargelli V, Rotellini M, Bartolucci G, Crocini C, Sacconi L, Tesi C, Belardinelli L, Tardiff J, Mugelli A, Olivotto I, Cerbai E, Poggesi C.

Circ Heart Fail. 2017 Mar;10(3). pii: e003565. doi: 10.1161/CIRCHEARTFAILURE.116.003565.

PMID:
28255011
11.

Electrical defects of the transverse-axial tubular system in cardiac diseases.

Crocini C, Ferrantini C, Coppini R, Sacconi L.

J Physiol. 2017 Jun 15;595(12):3815-3822. doi: 10.1113/JP273042. Epub 2017 Jan 17. Review.

12.

Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation.

Crocini C, Ferrantini C, Coppini R, Scardigli M, Yan P, Loew LM, Smith G, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Sci Rep. 2016 Oct 17;6:35628. doi: 10.1038/srep35628.

13.

T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure.

Crocini C, Coppini R, Ferrantini C, Yan P, Loew LM, Poggesi C, Cerbai E, Pavone FS, Sacconi L.

Int J Mol Sci. 2016 Sep 3;17(9). pii: E1471. doi: 10.3390/ijms17091471.

14.

Clearing of fixed tissue: a review from a microscopist's perspective.

Silvestri L, Costantini I, Sacconi L, Pavone FS.

J Biomed Opt. 2016 Aug;21(8):081205. doi: 10.1117/1.JBO.21.8.081205. Review.

PMID:
27020691
15.

Computer-based automatic identification of neurons in gigavoxel-sized 3D human brain images.

Soda P, Acciai L, Cordelli E, Costantini I, Sacconi L, Pavone FS, Conti V, Guerrini R, Frasconi P, Iannello G.

Conf Proc IEEE Eng Med Biol Soc. 2015;2015:7724-7. doi: 10.1109/EMBC.2015.7320182.

PMID:
26738082
16.

Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.

Crocini C, Ferrantini C, Scardigli M, Coppini R, Mazzoni L, Lazzeri E, Pioner JM, Scellini B, Guo A, Song LS, Yan P, Loew LM, Tardiff J, Tesi C, Vanzi F, Cerbai E, Pavone FS, Sacconi L, Poggesi C.

J Mol Cell Cardiol. 2016 Feb;91:42-51. doi: 10.1016/j.yjmcc.2015.12.013. Epub 2015 Dec 20.

17.

Label-free near-infrared reflectance microscopy as a complimentary tool for two-photon fluorescence brain imaging.

Allegra Mascaro AL, Costantini I, Margoni E, Iannello G, Bria A, Sacconi L, Pavone FS.

Biomed Opt Express. 2015 Oct 21;6(11):4483-92. doi: 10.1364/BOE.6.004483. eCollection 2015 Nov 1.

18.

Multi-Modal Optical Imaging of the Cerebellum in Animals.

Allegra Mascaro AL, Sacconi L, Silvestri L, Knott G, Pavone FS.

Cerebellum. 2015 Oct 17. [Epub ahead of print]

PMID:
26476852
19.

Comprehensive optical and data management infrastructure for high-throughput light-sheet microscopy of whole mouse brains.

Müllenbroich MC, Silvestri L, Onofri L, Costantini I, Hoff MV, Sacconi L, Iannello G, Pavone FS.

Neurophotonics. 2015 Oct;2(4):041404. doi: 10.1117/1.NPh.2.4.041404. Epub 2015 Jun 29.

20.

A versatile clearing agent for multi-modal brain imaging.

Costantini I, Ghobril JP, Di Giovanna AP, Allegra Mascaro AL, Silvestri L, Müllenbroich MC, Onofri L, Conti V, Vanzi F, Sacconi L, Guerrini R, Markram H, Iannello G, Pavone FS.

Sci Rep. 2015 May 7;5:9808. doi: 10.1038/srep09808.

21.

Towards a comprehensive understanding of brain machinery by correlative microscopy.

Allegra Mascaro AL, Silvestri L, Sacconi L, Pavone FS.

J Biomed Opt. 2015 Jun;20(6):61105. doi: 10.1117/1.JBO.20.6.061105. Review. No abstract available.

PMID:
25749101
22.

Functional cardiac imaging by random access microscopy.

Crocini C, Coppini R, Ferrantini C, Pavone FS, Sacconi L.

Front Physiol. 2014 Oct 20;5:403. doi: 10.3389/fphys.2014.00403. eCollection 2014.

23.

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure.

Crocini C, Coppini R, Ferrantini C, Yan P, Loew LM, Tesi C, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):15196-201. doi: 10.1073/pnas.1411557111. Epub 2014 Oct 6.

24.

Laser nanosurgery of cerebellar axons in vivo.

Allegra Mascaro AL, Sacconi L, Pavone FS.

J Vis Exp. 2014 Jul 28;(89):e51371. doi: 10.3791/51371.

25.

The theory of pattern formation on directed networks.

Asllani M, Challenger JD, Pavone FS, Sacconi L, Fanelli D.

Nat Commun. 2014 Jul 31;5:4517. doi: 10.1038/ncomms5517.

PMID:
25077521
26.

Impact of detubulation on force and kinetics of cardiac muscle contraction.

Ferrantini C, Coppini R, Sacconi L, Tosi B, Zhang ML, Wang GL, de Vries E, Hoppenbrouwers E, Pavone F, Cerbai E, Tesi C, Poggesi C, ter Keurs HE.

J Gen Physiol. 2014 Jun;143(6):783-97. doi: 10.1085/jgp.201311125.

27.

Correcting spherical aberrations in confocal light sheet microscopy: a theoretical study.

Silvestri L, Sacconi L, Pavone FS.

Microsc Res Tech. 2014 Jul;77(7):483-91. doi: 10.1002/jemt.22330. Epub 2014 Jan 3.

PMID:
24395714
28.

Micron-scale resolution optical tomography of entire mouse brains with confocal light sheet microscopy.

Silvestri L, Bria A, Costantini I, Sacconi L, Peng H, Iannello G, Pavone FS.

J Vis Exp. 2013 Oct 8;(80). doi: 10.3791/50696.

29.

The connectomics challenge.

Silvestri L, Sacconi L, Pavone FS.

Funct Neurol. 2013 Jul-Sep;28(3):167-73. doi: 10.11138/FNeur/2013.28.3.167. Review.

30.

The transverse-axial tubular system of cardiomyocytes.

Ferrantini C, Crocini C, Coppini R, Vanzi F, Tesi C, Cerbai E, Poggesi C, Pavone FS, Sacconi L.

Cell Mol Life Sci. 2013 Dec;70(24):4695-710. doi: 10.1007/s00018-013-1410-5. Epub 2013 Jul 12. Review.

PMID:
23846763
31.

Correlative two-photon and light sheet microscopy.

Silvestri L, Allegra Mascaro AL, Costantini I, Sacconi L, Pavone FS.

Methods. 2014 Mar 15;66(2):268-72. doi: 10.1016/j.ymeth.2013.06.013. Epub 2013 Jun 24.

PMID:
23806642
32.

In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex.

Allegra Mascaro AL, Cesare P, Sacconi L, Grasselli G, Mandolesi G, Maco B, Knott GW, Huang L, De Paola V, Strata P, Pavone FS.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10824-9. doi: 10.1073/pnas.1219256110. Epub 2013 Jun 10.

33.

Two-photon microscopy imaging of thy1GFP-M transgenic mice: a novel animal model to investigate brain dendritic cell subsets in vivo.

Laperchia C, Allegra Mascaro AL, Sacconi L, Andrioli A, Mattè A, De Franceschi L, Grassi-Zucconi G, Bentivoglio M, Buffelli M, Pavone FS.

PLoS One. 2013;8(2):e56144. doi: 10.1371/journal.pone.0056144. Epub 2013 Feb 7.

34.

Palette of fluorinated voltage-sensitive hemicyanine dyes.

Yan P, Acker CD, Zhou WL, Lee P, Bollensdorff C, Negrean A, Lotti J, Sacconi L, Antic SD, Kohl P, Mansvelder HD, Pavone FS, Loew LM.

Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20443-8. doi: 10.1073/pnas.1214850109. Epub 2012 Nov 20.

35.

Confocal light sheet microscopy: micron-scale neuroanatomy of the entire mouse brain.

Silvestri L, Bria A, Sacconi L, Iannello G, Pavone FS.

Opt Express. 2012 Aug 27;20(18):20582-98. doi: 10.1364/OE.20.020582.

PMID:
23037106
36.

Protein conformation and molecular order probed by second-harmonic-generation microscopy.

Vanzi F, Sacconi L, Cicchi R, Pavone FS.

J Biomed Opt. 2012 Jun;17(6):060901. doi: 10.1117/1.JBO.17.6.060901. Review.

PMID:
22734730
37.

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

Sacconi L, Ferrantini C, Lotti J, Coppini R, Yan P, Loew LM, Tesi C, Cerbai E, Poggesi C, Pavone FS.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5815-9. doi: 10.1073/pnas.1120188109. Epub 2012 Mar 26.

38.

Multi-photon nanosurgery in live brain.

Allegra Mascaro AL, Sacconi L, Pavone FS.

Front Neuroenergetics. 2010 Jul 30;2. pii: 21. doi: 10.3389/fnene.2010.00021. eCollection 2010.

39.

Probing myosin structural conformation in vivo by second-harmonic generation microscopy.

Nucciotti V, Stringari C, Sacconi L, Vanzi F, Fusi L, Linari M, Piazzesi G, Lombardi V, Pavone FS.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7763-8. doi: 10.1073/pnas.0914782107. Epub 2010 Apr 12.

40.

Optical recording of electrical activity in intact neuronal networks with random access second-harmonic generation microscopy.

Sacconi L, Mapelli J, Gandolfi D, Lotti J, O'Connor RP, D'Angelo E, Pavone FS.

Opt Express. 2008 Sep 15;16(19):14910-21.

PMID:
18795028
41.

Three-dimensional magneto-optic trap for micro-object manipulation.

Sacconi L, Romano G, Ballerini R, Capitanio M, De Pas M, Giuntini M, Dunlap D, Finzi L, Pavone FS.

Opt Lett. 2001 Sep 1;26(17):1359-61.

PMID:
18049608
42.

In vivo multiphoton nanosurgery on cortical neurons.

Sacconi L, O'Connor RP, Jasaitis A, Masi A, Buffelli M, Pavone FS.

J Biomed Opt. 2007 Sep-Oct;12(5):050502.

PMID:
17994859
43.

Analysis of kinetics in noisy systems: application to single molecule tethered particle motion.

Vanzi F, Sacconi L, Pavone FS.

Biophys J. 2007 Jul 1;93(1):21-36. Epub 2007 Apr 13.

44.

New techniques in linear and non-linear laser optics in muscle research.

Vanzi F, Capitanio M, Sacconi L, Stringari C, Cicchi R, Canepari M, Maffei M, Piroddi N, Poggesi C, Nucciotti V, Linari M, Piazzesi G, Tesi C, Antolini R, Lombardi V, Bottinelli R, Pavone FS.

J Muscle Res Cell Motil. 2006;27(5-7):469-79. Epub 2006 Aug 24. Review.

PMID:
16933024
45.

Cell imaging and manipulation by nonlinear optical microscopy.

Sacconi L, Tolic-Nørrelykke IM, D'Amico M, Vanzi F, Olivotto M, Antolini R, Pavone FS.

Cell Biochem Biophys. 2006;45(3):289-302. Review.

PMID:
16845175
46.

Lac repressor hinge flexibility and DNA looping: single molecule kinetics by tethered particle motion.

Vanzi F, Broggio C, Sacconi L, Pavone FS.

Nucleic Acids Res. 2006 Jul 11;34(12):3409-20. Print 2006.

47.

Overcoming photodamage in second-harmonic generation microscopy: real-time optical recording of neuronal action potentials.

Sacconi L, Dombeck DA, Webb WW.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3124-9. Epub 2006 Feb 17.

48.

Optical recording of fast neuronal membrane potential transients in acute mammalian brain slices by second-harmonic generation microscopy.

Dombeck DA, Sacconi L, Blanchard-Desce M, Webb WW.

J Neurophysiol. 2005 Nov;94(5):3628-36. Epub 2005 Aug 10.

49.

Nuclear and division-plane positioning revealed by optical micromanipulation.

Tolic-Nørrelykke IM, Sacconi L, Stringari C, Raabe I, Pavone FS.

Curr Biol. 2005 Jul 12;15(13):1212-6.

50.

Second-harmonic generation sensitivity to transmembrane potential in normal and tumor cells.

Sacconi L, D'Amico M, Vanzi F, Biagiotti T, Antolini R, Olivotto M, Pavone FS.

J Biomed Opt. 2005 Mar-Apr;10(2):024014.

PMID:
15910088

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