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Items: 1 to 50 of 333

1.

In Human Immunodeficiency Virus primary infection, early combined antiretroviral therapy reduced γδ T-cell activation but failed to restore their polyfunctionality.

Casetti R, Sacchi A, Bordoni V, Grassi G, Cimini E, Besi F, Pinnetti C, Mondi A, Antinori A, Agrati C.

Immunology. 2019 Aug;157(4):322-330. doi: 10.1111/imm.13089. Epub 2019 Jul 8.

PMID:
31206171
2.

Identification of novel indole derivatives acting as inhibitors of the Keap1-Nrf2 interaction.

Cosimelli B, Greco G, Laneri S, Novellino E, Sacchi A, Amendola G, Cosconati S, Bortolozzi R, Viola G.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):1152-1157. doi: 10.1080/14756366.2019.1623209.

3.

Spatiotemporal Regulation of Tumor Angiogenesis by Circulating Chromogranin A Cleavage and Neuropilin-1 Engagement.

Dallatomasina A, Gasparri AM, Colombo B, Sacchi A, Bianco M, Daniele T, Esposito A, Pastorino F, Ponzoni M, Marcucci F, Curnis F, Corti A.

Cancer Res. 2019 Apr 15;79(8):1925-1937. doi: 10.1158/0008-5472.CAN-18-0289. Epub 2019 Feb 22.

PMID:
30796053
4.

Enhancement of Tumor Homing by Chemotherapy-Loaded Nanoparticles.

Ponzoni M, Curnis F, Brignole C, Bruno S, Guarnieri D, Sitia L, Marotta R, Sacchi A, Bauckneht M, Buschiazzo A, Rossi A, Di Paolo D, Perri P, Gori A, Sementa AR, Emionite L, Cilli M, Tamma R, Ribatti D, Pompa PP, Marini C, Sambuceti G, Corti A, Pastorino F.

Small. 2018 Nov;14(45):e1802886. doi: 10.1002/smll.201802886. Epub 2018 Oct 7.

PMID:
30294852
5.

A new procedure to analyze polymorphonuclear myeloid derived suppressor cells in cryopreserved samples cells by flow cytometry.

Sacchi A, Tumino N, Grassi G, Casetti R, Cimini E, Bordoni V, Ammassari A, Antinori A, Agrati C.

PLoS One. 2018 Aug 30;13(8):e0202920. doi: 10.1371/journal.pone.0202920. eCollection 2018.

6.

Studies on enantioselectivity of chiral 4-acetylamino-6-alkyloxy-2-alkylthiopyrimidines acting as antagonists of the human A3 adenosine receptor.

Cosimelli B, Greco G, Laneri S, Novellino E, Sacchi A, Collina S, Rossi D, Cosconati S, Barresi E, Taliani S, Trincavelli ML, Martini C.

Medchemcomm. 2017 Nov 9;9(1):81-86. doi: 10.1039/c7md00375g. eCollection 2018 Jan 1.

7.

Lab to Field Assessment of the Ecotoxicological Impact of Chlorpyrifos, Isoproturon, or Tebuconazole on the Diversity and Composition of the Soil Bacterial Community.

Storck V, Nikolaki S, Perruchon C, Chabanis C, Sacchi A, Pertile G, Baguelin C, Karas PA, Spor A, Devers-Lamrani M, Papadopoulou ES, Sibourg O, Malandain C, Trevisan M, Ferrari F, Karpouzas DG, Tsiamis G, Martin-Laurent F.

Front Microbiol. 2018 Jun 29;9:1412. doi: 10.3389/fmicb.2018.01412. eCollection 2018.

8.

Myeloid-Derived Suppressor Cells Specifically Suppress IFN-γ Production and Antitumor Cytotoxic Activity of Vδ2 T Cells.

Sacchi A, Tumino N, Sabatini A, Cimini E, Casetti R, Bordoni V, Grassi G, Agrati C.

Front Immunol. 2018 Jun 6;9:1271. doi: 10.3389/fimmu.2018.01271. eCollection 2018.

9.

Succinimide-Based Conjugates Improve IsoDGR Cyclopeptide Affinity to αvβ3 without Promoting Integrin Allosteric Activation.

Nardelli F, Paissoni C, Quilici G, Gori A, Traversari C, Valentinis B, Sacchi A, Corti A, Curnis F, Ghitti M, Musco G.

J Med Chem. 2018 Sep 13;61(17):7474-7485. doi: 10.1021/acs.jmedchem.8b00745. Epub 2018 Jun 26.

PMID:
29883545
10.

Rise and fall of outbreak-specific clone inside endemic pulsotype of Salmonella 4,[5],12:i:-; insights from high-resolution molecular surveillance in Emilia-Romagna, Italy, 2012 to 2015.

Morganti M, Bolzoni L, Scaltriti E, Casadei G, Carra E, Rossi L, Gherardi P, Faccini F, Arrigoni N, Sacchi AR, Delledonne M, Pongolini S.

Euro Surveill. 2018 Mar;23(13). doi: 10.2807/1560-7917.ES.2018.23.13.17-00375.

11.

High-Frame Rate Vector Flow Imaging of the Carotid Bifurcation in Healthy Adults: Comparison With Color Doppler Imaging.

Goddi A, Bortolotto C, Raciti MV, Fiorina I, Aiani L, Magistretti G, Sacchi A, Tinelli C, Calliada F.

J Ultrasound Med. 2018 Sep;37(9):2263-2275. doi: 10.1002/jum.14579. Epub 2018 Mar 25.

PMID:
29574932
12.

IL-18 and Stem Cell Factor affect hematopoietic progenitor cells in HIV-infected patients treated during primary HIV infection.

Bordoni V, Viola D, Sacchi A, Pinnetti C, Casetti R, Cimini E, Tumino N, Antinori A, Ammassari A, Agrati C.

Cytokine. 2018 Mar;103:34-37. doi: 10.1016/j.cyto.2017.12.033. Epub 2018 Jan 8.

PMID:
29324258
13.

Intrahepatic Vγ9Vδ2 T-cells from HCV-infected patients show an exhausted phenotype but can inhibit HCV replication.

Cimini E, Bordoni V, Sacchi A, Visco-Comandini U, Montalbano M, Taibi C, Casetti R, Lalle E, D'Offizi G, Capobianchi MR, Agrati C.

Virus Res. 2018 Jan 2;243:31-35. doi: 10.1016/j.virusres.2017.10.008. Epub 2017 Oct 10.

PMID:
29029951
14.

Glycine N-methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing.

Corti A, Gasparri AM, Ghitti M, Sacchi A, Sudati F, Fiocchi M, Buttiglione V, Perani L, Gori A, Valtorta S, Moresco RM, Pastorino F, Ponzoni M, Musco G, Curnis F.

Adv Funct Mater. 2017 Sep 26;27(36). pii: 1701245. doi: 10.1002/adfm.201701245.

15.

Erratum to: Respiratory diphtheria due to Corynebacterium ulcerans transmitted by a companion dog, Italy 2014.

Monaco M, Sacchi AR, Scotti M, Mancini F, Riccio C, Errico G, Ratti G, Bondi F, Ciervo A, Pantosti A.

Infection. 2017 Dec;45(6):931. doi: 10.1007/s15010-017-1045-9. No abstract available.

PMID:
28786003
16.

Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells.

Cimini E, Castilletti C, Sacchi A, Casetti R, Bordoni V, Romanelli A, Turchi F, Martini F, Tumino N, Nicastri E, Corpolongo A, Di Caro A, Kobinger G, Zumla A, Capobianchi MR, Ippolito G, Agrati C.

Sci Rep. 2017 Jul 24;7(1):6313. doi: 10.1038/s41598-017-06536-x.

17.

Dendritic cells activation is associated with sustained virological response to telaprevir treatment of HCV-infected patients.

Sacchi A, Tumino N, Turchi F, Refolo G, Fimia G, Ciccosanti F, Montalbano M, Lionetti R, Taibi C, D'Offizi G, Casetti R, Bordoni V, Cimini E, Martini F, Agrati C.

Clin Immunol. 2017 Oct;183:82-90. doi: 10.1016/j.clim.2017.07.017. Epub 2017 Jul 20.

PMID:
28736275
18.

Rituximab alone as induction therapy for membranous lupus nephritis: A multicenter retrospective study.

Chavarot N, Verhelst D, Pardon A, Caudwell V, Mercadal L, Sacchi A, Leonardi C, Le Guern V, Karras A, Daugas E; Groupe Coopératif sur le Lupus Rénal.

Medicine (Baltimore). 2017 Jul;96(27):e7429. doi: 10.1097/MD.0000000000007429.

19.

Respiratory diphtheria due to Corynebacterium ulcerans transmitted by a companion dog, Italy 2014.

Monaco M, Sacchi AR, Scotti M, Mancini F, Riccio C, Errico G, Ratti G, Bondi F, Ciervo A, Pantosti A.

Infection. 2017 Dec;45(6):903-905. doi: 10.1007/s15010-017-1040-1. Epub 2017 Jun 24. Erratum in: Infection. 2017 Dec;45(6):931.

PMID:
28647898
20.

Different features of Vδ2 T and NK cells in fatal and non-fatal human Ebola infections.

Cimini E, Viola D, Cabeza-Cabrerizo M, Romanelli A, Tumino N, Sacchi A, Bordoni V, Casetti R, Turchi F, Martini F, Bore JA, Koundouno FR, Duraffour S, Michel J, Holm T, Zekeng EG, Cowley L, Garcia Dorival I, Doerrbecker J, Hetzelt N, Baum JHJ, Portmann J, Wölfel R, Gabriel M, Miranda O, Díaz G, Díaz JE, Fleites YA, Piñeiro CA, Castro CM, Koivogui L, Magassouba N, Diallo B, Ruibal P, Oestereich L, Wozniak DM, Lüdtke A, Becker-Ziaja B, Capobianchi MR, Ippolito G, Carroll MW, Günther S, Di Caro A, Muñoz-Fontela C, Agrati C.

PLoS Negl Trop Dis. 2017 May 30;11(5):e0005645. doi: 10.1371/journal.pntd.0005645. eCollection 2017 May.

21.

HIV-Specific CD8 T Cells Producing CCL-4 Are Associated With Worse Immune Reconstitution During Chronic Infection.

Casetti R, Pinnetti C, Sacchi A, De Simone G, Bordoni V, Cimini E, Tumino N, Besi F, Viola D, Turchi F, Mazzotta V, Antinori A, Martini F, Ammassari A, Agrati C.

J Acquir Immune Defic Syndr. 2017 Jul 1;75(3):338-344. doi: 10.1097/QAI.0000000000001392.

PMID:
28418988
22.

In HIV/HCV co-infected patients T regulatory and myeloid-derived suppressor cells persist after successful treatment with directly acting antivirals.

Tumino N, Casetti R, Fabbri G, Cimini E, Romanelli A, Turchi F, Forini O, Bordoni V, Antinori A, Ammassari A, Sacchi A, Agrati C.

J Hepatol. 2017 Aug;67(2):422-424. doi: 10.1016/j.jhep.2017.03.036. Epub 2017 Apr 12. No abstract available.

PMID:
28411041
23.

Bone Marrow CD34+ Progenitor Cells from HIV-Infected Patients Show an Impaired T Cell Differentiation Potential Related to Proinflammatory Cytokines.

Bordoni V, Bibas M, Viola D, Sacchi A, Cimini E, Tumino N, Casetti R, Amendola A, Ammassari A, Agrati C, Martini F.

AIDS Res Hum Retroviruses. 2017 Jun;33(6):590-596. doi: 10.1089/AID.2016.0195. Epub 2017 Feb 22.

PMID:
28125903
24.

Granulocytic Myeloid-Derived Suppressor Cells Increased in Early Phases of Primary HIV Infection Depending on TRAIL Plasma Level.

Tumino N, Bilotta MT, Pinnetti C, Ammassari A, Antinori A, Turchi F, Agrati C, Casetti R, Bordoni V, Cimini E, Abbate I, Capobianchi MR, Martini F, Sacchi A.

J Acquir Immune Defic Syndr. 2017 Apr 15;74(5):575-582. doi: 10.1097/QAI.0000000000001283.

PMID:
28060224
25.

Modulation of Phenotype and Function of Human CD4+CD25+ T Regulatory Lymphocytes Mediated by cAMP-Elevating Agents.

Riccomi A, Gesa V, Sacchi A, De Magistris MT, Vendetti S.

Front Immunol. 2016 Sep 20;7:358. eCollection 2016.

26.

Regulation of tumor growth by circulating full-length chromogranin A.

Curnis F, Dallatomasina A, Bianco M, Gasparri A, Sacchi A, Colombo B, Fiocchi M, Perani L, Venturini M, Tacchetti C, Sen S, Borges R, Dondossola E, Esposito A, Mahata SK, Corti A.

Oncotarget. 2016 Nov 8;7(45):72716-72732. doi: 10.18632/oncotarget.12237.

27.

The Different Roles of Interleukin 7 and Interleukin 18 in Affecting Lymphoid Hematopoietic Progenitor Cells and CD4 Homeostasis in Naive Primary and Chronic HIV-Infected Patients.

Bordoni V, Sacchi A, Cimini E, Casetti R, Tumino N, Ammassari A, Agrati C, Martini F.

Clin Infect Dis. 2016 Dec 15;63(12):1683-1684. Epub 2016 Sep 23. No abstract available.

PMID:
27664242
28.

Ecological status and sources of anthropogenic contaminants in mangroves of the Wouri River Estuary (Cameroon).

Fusi M, Beone GM, Suciu NA, Sacchi A, Trevisan M, Capri E, Daffonchio D, Din N, Dahdouh-Guebas F, Cannicci S.

Mar Pollut Bull. 2016 Aug 30;109(2):723-33. doi: 10.1016/j.marpolbul.2016.06.104. Epub 2016 Jul 6.

PMID:
27394634
29.

4-amino-6-alkyloxy-2-alkylthiopyrimidine derivatives as novel non-nucleoside agonists for the adenosine A1 receptor.

Cosimelli B, Greco G, Laneri S, Novellino E, Sacchi A, Trincavelli ML, Giacomelli C, Taliani S, Da Settimo F, Martini C.

Chem Biol Drug Des. 2016 Nov;88(5):724-729. doi: 10.1111/cbdd.12801. Epub 2016 Jul 11.

PMID:
27282729
30.

NGR-tagged nano-gold: A new CD13-selective carrier for cytokine delivery to tumors.

Curnis F, Fiocchi M, Sacchi A, Gori A, Gasparri A, Corti A.

Nano Res. 2016 May;9(5):1393-1408. Epub 2016 Mar 4.

31.

TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis.

Santoro A, Mattace Raso G, Taliani S, Da Pozzo E, Simorini F, Costa B, Martini C, Laneri S, Sacchi A, Cosimelli B, Calignano A, Da Settimo F, Meli R.

Eur J Pharm Sci. 2016 Jun 10;88:124-31. doi: 10.1016/j.ejps.2016.04.006. Epub 2016 Apr 14.

PMID:
27094781
32.

Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection.

Agrati C, Castilletti C, Casetti R, Sacchi A, Falasca L, Turchi F, Tumino N, Bordoni V, Cimini E, Viola D, Lalle E, Bordi L, Lanini S, Martini F, Nicastri E, Petrosillo N, Puro V, Piacentini M, Di Caro A, Kobinger GP, Zumla A, Ippolito G, Capobianchi MR.

Cell Death Dis. 2016 Mar 31;7:e2164. doi: 10.1038/cddis.2016.55.

33.

Corneal Cross-Linking: Evaluating the Potential for a Lower Power, Shorter Duration Treatment.

Caruso C, Barbaro G, Epstein RL, Tronino D, Ostacolo C, Sacchi A, Pacente L, Del Prete A, Sala M, Troisi S.

Cornea. 2016 May;35(5):659-62. doi: 10.1097/ICO.0000000000000809.

34.

Chromogranin A Is Preferentially Cleaved into Proangiogenic Peptides in the Bone Marrow of Multiple Myeloma Patients.

Bianco M, Gasparri AM, Colombo B, Curnis F, Girlanda S, Ponzoni M, Bertilaccio MT, Calcinotto A, Sacchi A, Ferrero E, Ferrarini M, Chesi M, Bergsagel PL, Bellone M, Tonon G, Ciceri F, Marcatti M, Caligaris-Cappio F, Corti A.

Cancer Res. 2016 Apr 1;76(7):1781-91. doi: 10.1158/0008-5472.CAN-15-1637. Epub 2016 Feb 11.

35.

Prevention of Primary Cytomegalovirus Infection in Pregnancy.

Revello MG, Tibaldi C, Masuelli G, Frisina V, Sacchi A, Furione M, Arossa A, Spinillo A, Klersy C, Ceccarelli M, Gerna G, Todros T; CCPE Study Group.

EBioMedicine. 2015 Aug 6;2(9):1205-10. doi: 10.1016/j.ebiom.2015.08.003. eCollection 2015 Sep.

36.

Evaluation of collected outcome measures in axial spondyloarthritis in daily-care rheumatology settings: the experience of the RHEVER network.

Che H, Etcheto A, Dernis E, Nataf H, Boumier P, Breuillard P, Durandin-Truffinet M, Fechtenbaum J, Gaud-Listrat V, Giraud B, Hudry C, Labatide-Alanore S, Le Devic P, Le Goux P, Lebrun A, Maheu E, Moura B, Nguyen M, Sacchi A, Ayral X, Blanchais A, Neveu S, Dougados M, Moltó A.

Clin Exp Rheumatol. 2015 Nov-Dec;33(6):851-7. Epub 2015 Sep 28.

PMID:
26411931
37.

In HIV-positive patients, myeloid-derived suppressor cells induce T-cell anergy by suppressing CD3ζ expression through ELF-1 inhibition.

Tumino N, Turchi F, Meschi S, Lalle E, Bordoni V, Casetti R, Agrati C, Cimini E, Montesano C, Colizzi V, Martini F, Sacchi A.

AIDS. 2015 Nov 28;29(18):2397-407. doi: 10.1097/QAD.0000000000000871.

PMID:
26355672
38.

Improvement of Topical Palmitoylethanolamide Anti-Inflammatory Activity by Pegylated Prodrugs.

Tronino D, Russo R, Ostacolo C, Mazzolari A, De Caro C, Avagliano C, Laneri S, La Rana G, Sacchi A, Della Valle F, Vistoli G, Calignano A.

Mol Pharm. 2015 Sep 8;12(9):3369-79. doi: 10.1021/acs.molpharmaceut.5b00397. Epub 2015 Aug 24.

PMID:
26289562
39.

Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion.

Cossu I, Bottoni G, Loi M, Emionite L, Bartolini A, Di Paolo D, Brignole C, Piaggio F, Perri P, Sacchi A, Curnis F, Gagliani MC, Bruno S, Marini C, Gori A, Longhi R, Murgia D, Sementa AR, Cilli M, Tacchetti C, Corti A, Sambuceti G, Marchiò S, Ponzoni M, Pastorino F.

Biomaterials. 2015 Nov;68:89-99. doi: 10.1016/j.biomaterials.2015.07.054. Epub 2015 Aug 1.

40.

Vγ9Vδ2 T-Cell Polyfunctionality Is Differently Modulated in HAART-Treated HIV Patients according to CD4 T-Cell Count.

Casetti R, De Simone G, Sacchi A, Rinaldi A, Viola D, Agrati C, Bordoni V, Cimini E, Tumino N, Besi F, Martini F.

PLoS One. 2015 Jul 10;10(7):e0132291. doi: 10.1371/journal.pone.0132291. eCollection 2015.

41.

Primary and Chronic HIV Infection Differently Modulates Mucosal Vδ1 and Vδ2 T-Cells Differentiation Profile and Effector Functions.

Cimini E, Agrati C, D'Offizi G, Vlassi C, Casetti R, Sacchi A, Lionetti R, Bordoni V, Tumino N, Scognamiglio P, Martini F.

PLoS One. 2015 Jun 18;10(6):e0129771. doi: 10.1371/journal.pone.0129771. eCollection 2015.

42.

Granulocytic myeloid derived suppressor cells expansion during active pulmonary tuberculosis is associated with high nitric oxide plasma level.

El Daker S, Sacchi A, Tempestilli M, Carducci C, Goletti D, Vanini V, Colizzi V, Lauria FN, Martini F, Martino A.

PLoS One. 2015 Apr 16;10(4):e0123772. doi: 10.1371/journal.pone.0123772. eCollection 2015.

43.

Early ART in primary HIV infection may also preserve lymphopoiesis capability in circulating haematopoietic progenitor cells: a case report.

Bordoni V, Casetti R, Viola D, Abbate I, Rozera G, Sacchi A, Cimini E, Tumino N, Agrati C, Orchi N, Pinnetti C, Ammassari A, Martini F.

J Antimicrob Chemother. 2015 May;70(5):1598-600. doi: 10.1093/jac/dku559. Epub 2015 Jan 20. No abstract available.

PMID:
25604747
44.

HIV infection of monocytes-derived dendritic cells inhibits Vγ9Vδ2 T cells functions.

Sacchi A, Rinaldi A, Tumino N, Casetti R, Agrati C, Turchi F, Bordoni V, Cimini E, Martini F.

PLoS One. 2014 Oct 23;9(10):e111095. doi: 10.1371/journal.pone.0111095. eCollection 2014.

45.

Effect of chromogranin A-derived vasostatin-1 on laser-induced choroidal neovascularization in the mouse.

Maestroni S, Maestroni A, Ceglia S, Tremolada G, Mancino M, Sacchi A, Lattanzio R, Zucchiatti I, Corti A, Bandello F, Zerbini G.

Acta Ophthalmol. 2015 May;93(3):e218-22. doi: 10.1111/aos.12557. Epub 2014 Oct 1.

46.

Modulation of polyfunctional HIV-specific CD8 T cells in patients responding differently to antiretroviral therapy.

Casetti R, De Simone G, Sacchi A, Bordoni V, Viola D, Rinaldi A, Agrati C, Gioia C, Martini F.

Int J Immunopathol Pharmacol. 2014 Apr-Jun;27(2):291-7.

PMID:
25004842
47.

Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyridines as new inhibitors of the Wnt/β-catenin signaling.

Cosimelli B, Laneri S, Ostacolo C, Sacchi A, Severi E, Porcù E, Rampazzo E, Moro E, Basso G, Viola G.

Eur J Med Chem. 2014 Aug 18;83:45-56. doi: 10.1016/j.ejmech.2014.05.071. Epub 2014 Jun 6.

PMID:
24950489
48.

Chronic HIV-infected patients show an impaired dendritic cells differentiation of bone marrow CD34⁺ cells.

Bordoni V, Bibas M, Viola D, Sacchi A, Agrati C, Castelli G, Ammassari A, Amendola A, Abbate I, Martini F.

J Acquir Immune Defic Syndr. 2013 Dec 1;64(4):342-4. doi: 10.1097/QAI.0b013e3182a40ff7.

PMID:
24169119
49.

Isoxazole derivatives as potent transient receptor potential melastatin type 8 (TRPM8) agonists.

Ostacolo C, Ambrosino P, Russo R, Lo Monte M, Soldovieri MV, Laneri S, Sacchi A, Vistoli G, Taglialatela M, Calignano A.

Eur J Med Chem. 2013 Nov;69:659-69. doi: 10.1016/j.ejmech.2013.08.056. Epub 2013 Sep 20.

PMID:
24095758
50.

HIV impairs CD34+-derived monocytic precursor differentiation into functional dendritic cells.

Bordoni V, Castelli G, Montesoro E, Federico M, Sacchi A, Morsilli O, Agrati C, Martini F, Chelucci C.

Int J Immunopathol Pharmacol. 2013 Jul-Sep;26(3):717-24.

PMID:
24067468

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