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Items: 26


Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.

Steklov M, Pandolfi S, Baietti MF, Batiuk A, Carai P, Najm P, Zhang M, Jang H, Renzi F, Cai Y, Abbasi Asbagh L, Pastor T, De Troyer M, Simicek M, Radaelli E, Brems H, Legius E, Tavernier J, Gevaert K, Impens F, Messiaen L, Nussinov R, Heymans S, Eyckerman S, Sablina AA.

Science. 2018 Dec 7;362(6419):1177-1182. doi: 10.1126/science.aap7607. Epub 2018 Nov 15.


Cancer-associated chromosomal deletions: Size makes a difference.

Cai Y, Sablina AA.

Cell Cycle. 2016 Nov;15(21):2850-2851. Epub 2016 Jul 26. No abstract available.


p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.

Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, Boeckx B, Wijnhoven PW, Radaelli E, Vermi W, Leucci E, Lapouge G, Beck B, van den Oord J, Nakagawa S, Hirose T, Sablina AA, Lambrechts D, Aerts S, Blanpain C, Marine JC.

Nat Med. 2016 Aug;22(8):861-8. doi: 10.1038/nm.4135. Epub 2016 Jul 4.


Loss of Chromosome 8p Governs Tumor Progression and Drug Response by Altering Lipid Metabolism.

Cai Y, Crowther J, Pastor T, Abbasi Asbagh L, Baietti MF, De Troyer M, Vazquez I, Talebi A, Renzi F, Dehairs J, Swinnen JV, Sablina AA.

Cancer Cell. 2016 May 9;29(5):751-766. doi: 10.1016/j.ccell.2016.04.003.


OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.

Baietti MF, Simicek M, Abbasi Asbagh L, Radaelli E, Lievens S, Crowther J, Steklov M, Aushev VN, Martínez García D, Tavernier J, Sablina AA.

EMBO Mol Med. 2016 Mar 1;8(3):288-303. doi: 10.15252/emmm.201505972.


PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length.

Naetar N, Soundarapandian V, Litovchick L, Goguen KL, Sablina AA, Bowman-Colin C, Sicinski P, Hahn WC, DeCaprio JA, Livingston DM.

Mol Cell. 2014 Jun 19;54(6):932-45. doi: 10.1016/j.molcel.2014.04.023. Epub 2014 May 22.


The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.

Simicek M, Lievens S, Laga M, Guzenko D, Aushev VN, Kalev P, Baietti MF, Strelkov SV, Gevaert K, Tavernier J, Sablina AA.

Nat Cell Biol. 2013 Oct;15(10):1220-30. doi: 10.1038/ncb2847. Epub 2013 Sep 22.


[Stress granules in the cells with intact and discrupted microtubules: analysis with new algorithm of image processing].

Sablina AA, Chudinova EM, Nadezhdina ES, Ivanov PA.

Tsitologiia. 2012;54(7):560-5. Russian.


Protein phosphatase 2A as a potential target for anticancer therapy.

Kalev P, Sablina AA.

Anticancer Agents Med Chem. 2011 Jan;11(1):38-46. Review.


Identification of PP2A complexes and pathways involved in cell transformation.

Sablina AA, Hector M, Colpaert N, Hahn WC.

Cancer Res. 2010 Dec 15;70(24):10474-84. doi: 10.1158/0008-5472.CAN-10-2855.


PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma.

Puustinen P, Junttila MR, Vanhatupa S, Sablina AA, Hector ME, Teittinen K, Raheem O, Ketola K, Lin S, Kast J, Haapasalo H, Hahn WC, Westermarck J.

Cancer Res. 2009 Apr 1;69(7):2870-7. doi: 10.1158/0008-5472.CAN-08-2760. Epub 2009 Mar 17.


SV40 small T antigen and PP2A phosphatase in cell transformation.

Sablina AA, Hahn WC.

Cancer Metastasis Rev. 2008 Jun;27(2):137-46. doi: 10.1007/s10555-008-9116-0. Review.


Structural basis of PP2A inhibition by small t antigen.

Cho US, Morrone S, Sablina AA, Arroyo JD, Hahn WC, Xu W.

PLoS Biol. 2007 Aug;5(8):e202.


The role of PP2A A subunits in tumor suppression.

Sablina AA, Hahn WC.

Cell Adh Migr. 2007 Jul-Sep;1(3):140-1. Epub 2007 Jul 5. Review.


The tumor suppressor PP2A Abeta regulates the RalA GTPase.

Sablina AA, Chen W, Arroyo JD, Corral L, Hector M, Bulmer SE, DeCaprio JA, Hahn WC.

Cell. 2007 Jun 1;129(5):969-82.


The antioxidant function of the p53 tumor suppressor.

Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE, Chumakov PM.

Nat Med. 2005 Dec;11(12):1306-13. Epub 2005 Nov 13.


[Down-regulation of TRIP6 expression induces actin cytoskeleton rearrangements in human carcinoma cell lines].

Gur'ianova OA, Sablina AA, Chumakov PM, Frolova EI.

Mol Biol (Mosk). 2005 Sep-Oct;39(5):905-9. Russian.


Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD.

Budanov AV, Sablina AA, Feinstein E, Koonin EV, Chumakov PM.

Science. 2004 Apr 23;304(5670):596-600.


[The protective role of p53 in Ras-induced transformation of REF52 cells].

Kopnin PB, Ivanov AV, Il'inskaia GV, Sablina AA, Kopnin BP, Chumakov PM.

Mol Biol (Mosk). 2003 May-Jun;37(3):458-71. Russian.


Tumor suppressor p53 and its homologue p73alpha affect cell migration.

Sablina AA, Chumakov PM, Kopnin BP.

J Biol Chem. 2003 Jul 25;278(30):27362-71. Epub 2003 May 15.


Dual-colour imaging of membrane protein targeting directed by poa semilatent virus movement protein TGBp3 in plant and mammalian cells.

Zamyatnin AA Jr, Solovyev AG, Sablina AA, Agranovsky AA, Katul L, Vetten HJ, Schiemann J, Hinkkanen AE, Lehto K, Morozov SY.

J Gen Virol. 2002 Mar;83(Pt 3):651-62.


[KAISO--a new member of the BTB/POZ family specifically bindsto methylated DNA sequences].

Prokhorchuk AV, Aĭtkhozhina DS, Sablina AA, Ruzov AS, Prokhorchuk EB.

Genetika. 2001 Jun;37(6):737-44. Russian.


p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling.

Sablina AA, Chumakov PM, Levine AJ, Kopnin BP.

Oncogene. 2001 Feb 22;20(8):899-909.


P53-dependent effects of RAS oncogene on chromosome stability and cell cycle checkpoints.

Agapova LS, Ivanov AV, Sablina AA, Kopnin PB, Sokova OI, Chumakov PM, Kopnin BP.

Oncogene. 1999 May 20;18(20):3135-42.


Activation of p53-mediated cell cycle checkpoint in response to micronuclei formation.

Sablina AA, Ilyinskaya GV, Rubtsova SN, Agapova LS, Chumakov PM, Kopnin BP.

J Cell Sci. 1998 Apr;111 ( Pt 7):977-84.

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