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Items: 36

1.

Radiosensitization approaches for HPV-positive and HPV-negative head and neck squamous carcinomas.

Dok R, Bamps M, Glorieux M, Zhao P, Sablina A, Nuyts S.

Int J Cancer. 2019 Jul 8. doi: 10.1002/ijc.32558. [Epub ahead of print]

PMID:
31283004
2.

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.

Steklov M, Pandolfi S, Baietti MF, Batiuk A, Carai P, Najm P, Zhang M, Jang H, Renzi F, Cai Y, Abbasi Asbagh L, Pastor T, De Troyer M, Simicek M, Radaelli E, Brems H, Legius E, Tavernier J, Gevaert K, Impens F, Messiaen L, Nussinov R, Heymans S, Eyckerman S, Sablina AA.

Science. 2018 Dec 7;362(6419):1177-1182. doi: 10.1126/science.aap7607. Epub 2018 Nov 15.

PMID:
30442762
3.

PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development.

Sents W, Meeusen B, Kalev P, Radaelli E, Sagaert X, Miermans E, Haesen D, Lambrecht C, Dewerchin M, Carmeliet P, Westermarck J, Sablina A, Janssens V.

Cancer Res. 2017 Dec 15;77(24):6825-6837. doi: 10.1158/0008-5472.CAN-16-2911. Epub 2017 Oct 18.

4.

Loss of protein phosphatase 2A regulatory subunit B56δ promotes spontaneous tumorigenesis in vivo.

Lambrecht C, Libbrecht L, Sagaert X, Pauwels P, Hoorne Y, Crowther J, Louis JV, Sents W, Sablina A, Janssens V.

Oncogene. 2018 Jan 25;37(4):544-552. doi: 10.1038/onc.2017.350. Epub 2017 Oct 2.

PMID:
28967903
5.

Cancer-associated chromosomal deletions: Size makes a difference.

Cai Y, Sablina AA.

Cell Cycle. 2016 Nov;15(21):2850-2851. Epub 2016 Jul 26. No abstract available.

6.

Nuclear p16INK4a expression predicts enhanced radiation response in head and neck cancers.

Dok R, Abbasi Asbagh L, Van Limbergen EJ, Sablina A, Nuyts S.

Oncotarget. 2016 Jun 21;7(25):38785-38795. doi: 10.18632/oncotarget.9609.

7.

Therapeutic relevance of the protein phosphatase 2A in cancer.

Cunningham CE, Li S, Vizeacoumar FS, Bhanumathy KK, Lee JS, Parameswaran S, Furber L, Abuhussein O, Paul JM, McDonald M, Templeton SD, Shukla H, El Zawily AM, Boyd F, Alli N, Mousseau DD, Geyer R, Bonham K, Anderson DH, Yan J, Yu-Lee LY, Weaver BA, Uppalapati M, Ruppin E, Sablina A, Freywald A, Vizeacoumar FJ.

Oncotarget. 2016 Sep 20;7(38):61544-61561. doi: 10.18632/oncotarget.11399.

8.

Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth.

Haesen D, Abbasi Asbagh L, Derua R, Hubert A, Schrauwen S, Hoorne Y, Amant F, Waelkens E, Sablina A, Janssens V.

Cancer Res. 2016 Oct 1;76(19):5719-5731. Epub 2016 Aug 2.

9.

p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.

Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, Boeckx B, Wijnhoven PW, Radaelli E, Vermi W, Leucci E, Lapouge G, Beck B, van den Oord J, Nakagawa S, Hirose T, Sablina AA, Lambrechts D, Aerts S, Blanpain C, Marine JC.

Nat Med. 2016 Aug;22(8):861-8. doi: 10.1038/nm.4135. Epub 2016 Jul 4.

PMID:
27376578
10.

Loss of Chromosome 8p Governs Tumor Progression and Drug Response by Altering Lipid Metabolism.

Cai Y, Crowther J, Pastor T, Abbasi Asbagh L, Baietti MF, De Troyer M, Vazquez I, Talebi A, Renzi F, Dehairs J, Swinnen JV, Sablina AA.

Cancer Cell. 2016 May 9;29(5):751-766. doi: 10.1016/j.ccell.2016.04.003.

11.

OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.

Baietti MF, Simicek M, Abbasi Asbagh L, Radaelli E, Lievens S, Crowther J, Steklov M, Aushev VN, Martínez García D, Tavernier J, Sablina AA.

EMBO Mol Med. 2016 Mar 1;8(3):288-303. doi: 10.15252/emmm.201505972.

12.

The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling.

Asbagh LA, Vazquez I, Vecchione L, Budinska E, De Vriendt V, Baietti MF, Steklov M, Jacobs B, Hoe N, Singh S, Imjeti NS, Zimmermann P, Sablina A, Tejpar S.

Oncotarget. 2014 Oct 30;5(20):10070-83.

13.

PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length.

Naetar N, Soundarapandian V, Litovchick L, Goguen KL, Sablina AA, Bowman-Colin C, Sicinski P, Hahn WC, DeCaprio JA, Livingston DM.

Mol Cell. 2014 Jun 19;54(6):932-45. doi: 10.1016/j.molcel.2014.04.023. Epub 2014 May 22.

14.

p16INK4a impairs homologous recombination-mediated DNA repair in human papillomavirus-positive head and neck tumors.

Dok R, Kalev P, Van Limbergen EJ, Asbagh LA, Vázquez I, Hauben E, Sablina A, Nuyts S.

Cancer Res. 2014 Mar 15;74(6):1739-51. doi: 10.1158/0008-5472.CAN-13-2479. Epub 2014 Jan 28.

15.

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.

Simicek M, Lievens S, Laga M, Guzenko D, Aushev VN, Kalev P, Baietti MF, Strelkov SV, Gevaert K, Tavernier J, Sablina AA.

Nat Cell Biol. 2013 Oct;15(10):1220-30. doi: 10.1038/ncb2847. Epub 2013 Sep 22.

PMID:
24056301
16.

RNF4 is required for DNA double-strand break repair in vivo.

Vyas R, Kumar R, Clermont F, Helfricht A, Kalev P, Sotiropoulou P, Hendriks IA, Radaelli E, Hochepied T, Blanpain C, Sablina A, van Attikum H, Olsen JV, Jochemsen AG, Vertegaal AC, Marine JC.

Cell Death Differ. 2013 Mar;20(3):490-502. doi: 10.1038/cdd.2012.145. Epub 2012 Nov 30.

17.

Loss of PPP2R2A inhibits homologous recombination DNA repair and predicts tumor sensitivity to PARP inhibition.

Kalev P, Simicek M, Vazquez I, Munck S, Chen L, Soin T, Danda N, Chen W, Sablina A.

Cancer Res. 2012 Dec 15;72(24):6414-24. doi: 10.1158/0008-5472.CAN-12-1667. Epub 2012 Oct 18.

18.

[Stress granules in the cells with intact and discrupted microtubules: analysis with new algorithm of image processing].

Sablina AA, Chudinova EM, Nadezhdina ES, Ivanov PA.

Tsitologiia. 2012;54(7):560-5. Russian.

PMID:
23074858
19.

Protein phosphatase 2A as a potential target for anticancer therapy.

Kalev P, Sablina AA.

Anticancer Agents Med Chem. 2011 Jan;11(1):38-46. Review.

PMID:
21288198
20.

Identification of PP2A complexes and pathways involved in cell transformation.

Sablina AA, Hector M, Colpaert N, Hahn WC.

Cancer Res. 2010 Dec 15;70(24):10474-84. doi: 10.1158/0008-5472.CAN-10-2855.

21.

PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma.

Puustinen P, Junttila MR, Vanhatupa S, Sablina AA, Hector ME, Teittinen K, Raheem O, Ketola K, Lin S, Kast J, Haapasalo H, Hahn WC, Westermarck J.

Cancer Res. 2009 Apr 1;69(7):2870-7. doi: 10.1158/0008-5472.CAN-08-2760. Epub 2009 Mar 17.

22.

SV40 small T antigen and PP2A phosphatase in cell transformation.

Sablina AA, Hahn WC.

Cancer Metastasis Rev. 2008 Jun;27(2):137-46. doi: 10.1007/s10555-008-9116-0. Review.

PMID:
18214640
23.

Structural basis of PP2A inhibition by small t antigen.

Cho US, Morrone S, Sablina AA, Arroyo JD, Hahn WC, Xu W.

PLoS Biol. 2007 Aug;5(8):e202.

24.

The role of PP2A A subunits in tumor suppression.

Sablina AA, Hahn WC.

Cell Adh Migr. 2007 Jul-Sep;1(3):140-1. Epub 2007 Jul 5. Review.

25.

The tumor suppressor PP2A Abeta regulates the RalA GTPase.

Sablina AA, Chen W, Arroyo JD, Corral L, Hector M, Bulmer SE, DeCaprio JA, Hahn WC.

Cell. 2007 Jun 1;129(5):969-82.

26.

The antioxidant function of the p53 tumor suppressor.

Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE, Chumakov PM.

Nat Med. 2005 Dec;11(12):1306-13. Epub 2005 Nov 13.

27.

[Down-regulation of TRIP6 expression induces actin cytoskeleton rearrangements in human carcinoma cell lines].

Gur'ianova OA, Sablina AA, Chumakov PM, Frolova EI.

Mol Biol (Mosk). 2005 Sep-Oct;39(5):905-9. Russian.

28.

Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD.

Budanov AV, Sablina AA, Feinstein E, Koonin EV, Chumakov PM.

Science. 2004 Apr 23;304(5670):596-600.

29.

[The protective role of p53 in Ras-induced transformation of REF52 cells].

Kopnin PB, Ivanov AV, Il'inskaia GV, Sablina AA, Kopnin BP, Chumakov PM.

Mol Biol (Mosk). 2003 May-Jun;37(3):458-71. Russian.

PMID:
12815953
30.

Tumor suppressor p53 and its homologue p73alpha affect cell migration.

Sablina AA, Chumakov PM, Kopnin BP.

J Biol Chem. 2003 Jul 25;278(30):27362-71. Epub 2003 May 15.

31.

Dual-colour imaging of membrane protein targeting directed by poa semilatent virus movement protein TGBp3 in plant and mammalian cells.

Zamyatnin AA Jr, Solovyev AG, Sablina AA, Agranovsky AA, Katul L, Vetten HJ, Schiemann J, Hinkkanen AE, Lehto K, Morozov SY.

J Gen Virol. 2002 Mar;83(Pt 3):651-62.

PMID:
11842260
32.

[KAISO--a new member of the BTB/POZ family specifically bindsto methylated DNA sequences].

Prokhorchuk AV, Aĭtkhozhina DS, Sablina AA, Ruzov AS, Prokhorchuk EB.

Genetika. 2001 Jun;37(6):737-44. Russian.

PMID:
11517759
33.

p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling.

Sablina AA, Chumakov PM, Levine AJ, Kopnin BP.

Oncogene. 2001 Feb 22;20(8):899-909.

34.
35.

P53-dependent effects of RAS oncogene on chromosome stability and cell cycle checkpoints.

Agapova LS, Ivanov AV, Sablina AA, Kopnin PB, Sokova OI, Chumakov PM, Kopnin BP.

Oncogene. 1999 May 20;18(20):3135-42.

36.

Activation of p53-mediated cell cycle checkpoint in response to micronuclei formation.

Sablina AA, Ilyinskaya GV, Rubtsova SN, Agapova LS, Chumakov PM, Kopnin BP.

J Cell Sci. 1998 Apr;111 ( Pt 7):977-84.

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