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Items: 1 to 50 of 62

1.

IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer.

Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Solé L, González-Farré M, Alonso J, Montagut C, Martinez-Iniesta M, Bertran J, Borràs E, Iglesias M, Sabidó E, Bigas A, Boulton SJ, Espinosa L.

Mol Cell. 2019 Jul 4. pii: S1097-2765(19)30433-2. doi: 10.1016/j.molcel.2019.05.036. [Epub ahead of print]

PMID:
31302002
Free Article
2.

Proteomic study of the membrane components of signalling cascades of Botrytis cinerea controlled by phosphorylation.

Escobar-Niño A, Liñeiro E, Amil F, Carrasco R, Chiva C, Fuentes C, Blanco-Ulate B, Cantoral Fernández JM, Sabidó E, Fernández-Acero FJ.

Sci Rep. 2019 Jul 8;9(1):9860. doi: 10.1038/s41598-019-46270-0.

3.

Protein-based cardiogenic shock patient classifier.

Rueda F, Borràs E, García-García C, Iborra-Egea O, Revuelta-López E, Harjola VP, Cediel G, Lassus J, Tarvasmäki T, Mebazaa A, Sabidó E, Bayés-Genís A.

Eur Heart J. 2019 Jun 17. pii: ehz294. doi: 10.1093/eurheartj/ehz294. [Epub ahead of print]

PMID:
31204432
4.

Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 (LRP1)-derived peptides against LDL aggregation.

Benitez-Amaro A, Pallara C, Nasarre L, Rivas-Urbina A, Benitez S, Vea A, Bornachea O, de Gonzalo-Calvo D, Serra-Mir G, Villegas S, Prades R, Sanchez-Quesada JL, Chiva C, Sabido E, Tarragó T, Llorente-Cortés V.

Biochim Biophys Acta Biomembr. 2019 Jul 1;1861(7):1302-1316. doi: 10.1016/j.bbamem.2019.05.003. Epub 2019 May 8.

PMID:
31077676
5.

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

Roewenstrunk J, Di Vona C, Chen J, Borras E, Dong C, Arató K, Sabidó E, Huen MSY, de la Luna S.

Sci Rep. 2019 Apr 12;9(1):6014. doi: 10.1038/s41598-019-42445-x.

6.

The cochaperone CHIP marks Hsp70- and Hsp90-bound substrates for degradation through a very flexible mechanism.

Quintana-Gallardo L, Martín-Benito J, Marcilla M, Espadas G, Sabidó E, Valpuesta JM.

Sci Rep. 2019 Mar 25;9(1):5102. doi: 10.1038/s41598-019-41060-0.

7.

Isotopologue Multipoint Calibration for Proteomics Biomarker Quantification in Clinical Practice.

Chiva C, Pastor O, Trilla-Fuertes L, Gámez-Pozo A, Fresno Vara JÁ, Sabidó E.

Anal Chem. 2019 Apr 16;91(8):4934-4938. doi: 10.1021/acs.analchem.8b05802. Epub 2019 Mar 25.

PMID:
30882204
8.

Chromatin capture links the metabolic enzyme AHCY to stem cell proliferation.

Aranda S, Alcaine-Colet A, Blanco E, Borràs E, Caillot C, Sabidó E, Di Croce L.

Sci Adv. 2019 Mar 6;5(3):eaav2448. doi: 10.1126/sciadv.aav2448. eCollection 2019 Mar.

9.

Unraveling the hidden universe of small proteins in bacterial genomes.

Miravet-Verde S, Ferrar T, Espadas-García G, Mazzolini R, Gharrab A, Sabido E, Serrano L, Lluch-Senar M.

Mol Syst Biol. 2019 Feb 22;15(2):e8290. doi: 10.15252/msb.20188290.

10.

Proteomics characterisation of central nervous system metastasis biomarkers in triple negative breast cancer.

Rojas L K, Trilla-Fuertes L, Gámez-Pozo A, Chiva C, Sepúlveda J, Manso L, Prado-Vázquez G, Zapater-Moros A, López-Vacas R, Ferrer-Gómez M, Mendiola C, Espinosa E, Sabidó E, Ciruelos E, Vara JÁF.

Ecancermedicalscience. 2019 Jan 15;13:891. doi: 10.3332/ecancer.2019.891. eCollection 2019.

11.

Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid.

Lleó A, Núñez-Llaves R, Alcolea D, Chiva C, Balateu-Paños D, Colom-Cadena M, Gomez-Giro G, Muñoz L, Querol-Vilaseca M, Pegueroles J, Rami L, Lladó A, Molinuevo JL, Tainta M, Clarimón J, Spires-Jones T, Blesa R, Fortea J, Martínez-Lage P, Sánchez-Valle R, Sabidó E, Bayés À, Belbin O.

Mol Cell Proteomics. 2019 Mar;18(3):546-560. doi: 10.1074/mcp.RA118.001290. Epub 2019 Jan 3.

PMID:
30606734
12.

MSstatsQC 2.0: R/Bioconductor Package for Statistical Quality Control of Mass Spectrometry-Based Proteomics Experiments.

Dogu E, Taheri SM, Olivella R, Marty F, Lienert I, Reiter L, Sabido E, Vitek O.

J Proteome Res. 2019 Feb 1;18(2):678-686. doi: 10.1021/acs.jproteome.8b00732. Epub 2018 Dec 14.

PMID:
30450913
13.

DIA+: A Data-Independent Acquisition Method Combining Multiple Precursor Charges to Improve Peptide Signal.

Borràs E, Sabidó E.

Anal Chem. 2018 Nov 6;90(21):12339-12341. doi: 10.1021/acs.analchem.8b03418. Epub 2018 Oct 11.

PMID:
30295461
14.

Knock-down of AHCY and depletion of adenosine induces DNA damage and cell cycle arrest.

Belužić L, Grbeša I, Belužić R, Park JH, Kong HK, Kopjar N, Espadas G, Sabidó E, Lepur A, Rokić F, Jerić I, Brkljačić L, Vugrek O.

Sci Rep. 2018 Sep 18;8(1):14012. doi: 10.1038/s41598-018-32356-8.

15.

Human Early Life Exposome (HELIX) study: a European population-based exposome cohort.

Maitre L, de Bont J, Casas M, Robinson O, Aasvang GM, Agier L, Andrušaitytė S, Ballester F, Basagaña X, Borràs E, Brochot C, Bustamante M, Carracedo A, de Castro M, Dedele A, Donaire-Gonzalez D, Estivill X, Evandt J, Fossati S, Giorgis-Allemand L, R Gonzalez J, Granum B, Grazuleviciene R, Bjerve Gützkow K, Småstuen Haug L, Hernandez-Ferrer C, Heude B, Ibarluzea J, Julvez J, Karachaliou M, Keun HC, Hjertager Krog N, Lau CE, Leventakou V, Lyon-Caen S, Manzano C, Mason D, McEachan R, Meltzer HM, Petraviciene I, Quentin J, Roumeliotaki T, Sabido E, Saulnier PJ, Siskos AP, Siroux V, Sunyer J, Tamayo I, Urquiza J, Vafeiadi M, van Gent D, Vives-Usano M, Waiblinger D, Warembourg C, Chatzi L, Coen M, van den Hazel P, Nieuwenhuijsen MJ, Slama R, Thomsen C, Wright J, Vrijheid M.

BMJ Open. 2018 Sep 10;8(9):e021311. doi: 10.1136/bmjopen-2017-021311.

16.

Proteomic Profiling of Microtubule Self-organization in M-phase.

Rosas-Salvans M, Cavazza T, Espadas G, Sabido E, Vernos I.

Mol Cell Proteomics. 2018 Oct;17(10):1991-2004. doi: 10.1074/mcp.RA118.000745. Epub 2018 Jul 3.

PMID:
29970457
17.

Aging-related tau astrogliopathy (ARTAG): not only tau phosphorylation in astrocytes.

Ferrer I, García MA, González IL, Lucena DD, Villalonga AR, Tech MC, Llorens F, Garcia-Esparcia P, Martinez-Maldonado A, Mendez MF, Escribano BT, Bech-Serra JJ, Sabido E, de la Torre Gómez C, Del Rio JA.

Brain Pathol. 2018 Nov;28(6):965-985. doi: 10.1111/bpa.12593. Epub 2018 Feb 25.

PMID:
29396893
18.

QCloud: A cloud-based quality control system for mass spectrometry-based proteomics laboratories.

Chiva C, Olivella R, Borràs E, Espadas G, Pastor O, Solé A, Sabidó E.

PLoS One. 2018 Jan 11;13(1):e0189209. doi: 10.1371/journal.pone.0189209. eCollection 2018.

19.

Proteome profiling of clear cell renal cell carcinoma in von Hippel-Lindau patients highlights upregulation of Xaa-Pro aminopeptidase-1, an anti-proliferative and anti-migratory exoprotease.

Drendel V, Heckelmann B, Chen CY, Weisser J, Espadas G, Schell C, Sabido E, Werner M, Jilg CA, Schilling O.

Oncotarget. 2017 Oct 19;8(59):100066-100078. doi: 10.18632/oncotarget.21929. eCollection 2017 Nov 21.

20.

Proteotoxicity in cardiac amyloidosis: amyloidogenic light chains affect the levels of intracellular proteins in human heart cells.

Imperlini E, Gnecchi M, Rognoni P, Sabidò E, Ciuffreda MC, Palladini G, Espadas G, Mancuso FM, Bozzola M, Malpasso G, Valentini V, Palladini G, Orrù S, Ferraro G, Milani P, Perlini S, Salvatore F, Merlini G, Lavatelli F.

Sci Rep. 2017 Nov 15;7(1):15661. doi: 10.1038/s41598-017-15424-3.

21.

What is targeted proteomics? A concise revision of targeted acquisition and targeted data analysis in mass spectrometry.

Borràs E, Sabidó E.

Proteomics. 2017 Sep;17(17-18). doi: 10.1002/pmic.201700180.

PMID:
28719092
22.

Prediction of adjuvant chemotherapy response in triple negative breast cancer with discovery and targeted proteomics.

Gámez-Pozo A, Trilla-Fuertes L, Prado-Vázquez G, Chiva C, López-Vacas R, Nanni P, Berges-Soria J, Grossmann J, Díaz-Almirón M, Ciruelos E, Sabidó E, Espinosa E, Fresno Vara JÁ.

PLoS One. 2017 Jun 8;12(6):e0178296. doi: 10.1371/journal.pone.0178296. eCollection 2017.

23.
24.

Peptide Selection for Targeted Protein Quantitation.

Chiva C, Sabidó E.

J Proteome Res. 2017 Mar 3;16(3):1376-1380. doi: 10.1021/acs.jproteome.6b00115. Epub 2017 Jan 30.

PMID:
28102078
25.

A multicentric study to evaluate the use of relative retention times in targeted proteomics.

Vialas V, Colomé-Calls N, Abian J, Aloria K, Alvarez-Llamas G, Antúnez O, Arizmendi JM, Azkargorta M, Barceló-Batllori S, Barderas MG, Blanco F, Casal JI, Casas V, de la Torre C, Chicano-Gálvez E, Elortza F, Espadas G, Estanyol JM, Fernandez-Irigoyen J, Fernandez-Puente P, Fidalgo MJ, Fuentes M, Gay M, Gil C, Hainard A, Hernaez ML, Ibarrola N, Kopylov AT, Lario A, Lopez JA, López-Lucendo M, Marcilla M, Marina-Ramírez A, Marko-Varga G, Martín L, Mora MI, Morato-López E, Muñoz J, Odena MA, de Oliveira E, Orera I, Ortea I, Pasquarello C, Ray KB, Rezeli M, Ruppen I, Sabidó E, Del Pino MMS, Sancho J, Santamaría E, Vazquez J, Vilaseca M, Vivanco F, Walters JJ, Zgoda VG, Corrales FJ, Canals F, Paradela A.

J Proteomics. 2017 Jan 30;152:138-149. doi: 10.1016/j.jprot.2016.10.014. Epub 2016 Oct 29.

PMID:
27989941
26.

System-Wide Quantitative Proteomics of the Metabolic Syndrome in Mice: Genotypic and Dietary Effects.

Terfve C, Sabidó E, Wu Y, Gonçalves E, Choi M, Vaga S, Vitek O, Saez-Rodriguez J, Aebersold R.

J Proteome Res. 2017 Feb 3;16(2):831-841. doi: 10.1021/acs.jproteome.6b00815. Epub 2017 Jan 10.

PMID:
27936760
27.

Targeted proteomics in urinary extracellular vesicles identifies biomarkers for diagnosis and prognosis of prostate cancer.

Sequeiros T, Rigau M, Chiva C, Montes M, Garcia-Grau I, Garcia M, Diaz S, Celma A, Bijnsdorp I, Campos A, Di Mauro P, Borrós S, Reventós J, Doll A, Paciucci R, Pegtel M, de Torres I, Sabidó E, Morote J, Olivan M.

Oncotarget. 2017 Jan 17;8(3):4960-4976. doi: 10.18632/oncotarget.13634.

28.

High-Throughput Proteomics Reveals the Unicellular Roots of Animal Phosphosignaling and Cell Differentiation.

Sebé-Pedrós A, Peña MI, Capella-Gutiérrez S, Antó M, Gabaldón T, Ruiz-Trillo I, Sabidó E.

Dev Cell. 2016 Oct 24;39(2):186-197. doi: 10.1016/j.devcel.2016.09.019. Epub 2016 Oct 13.

29.

Dataset of the Botrytis cinerea phosphoproteome induced by different plant-based elicitors.

Liñeiro E, Chiva C, Cantoral JM, Sabido E, Fernández-Acero FJ.

Data Brief. 2016 Apr 22;7:1447-1450. eCollection 2016 Jun.

30.

Applications and Developments in Targeted Proteomics: From SRM to DIA/SWATH.

Aebersold R, Bensimon A, Collins BC, Ludwig C, Sabido E.

Proteomics. 2016 Aug;16(15-16):2065-7. doi: 10.1002/pmic.201600203. No abstract available.

PMID:
27542680
31.

Chemically synthesized peptide libraries as a new source of BBB shuttles. Use of mass spectrometry for peptide identification.

Guixer B, Arroyo X, Belda I, Sabidó E, Teixidó M, Giralt E.

J Pept Sci. 2016 Sep;22(9):577-91. doi: 10.1002/psc.2900. Epub 2016 Jul 20.

32.

Modifications of fungal membrane proteins profile under pathogenicity induction: A proteomic analysis of Botrytis cinerea membranome.

Liñeiro E, Chiva C, Cantoral JM, Sabidó E, Fernández-Acero FJ.

Proteomics. 2016 Sep;16(17):2363-76. doi: 10.1002/pmic.201500496. Epub 2016 Aug 5.

PMID:
27329576
33.

The Dynamic Regulatory Genome of Capsaspora and the Origin of Animal Multicellularity.

Sebé-Pedrós A, Ballaré C, Parra-Acero H, Chiva C, Tena JJ, Sabidó E, Gómez-Skarmeta JL, Di Croce L, Ruiz-Trillo I.

Cell. 2016 May 19;165(5):1224-1237. doi: 10.1016/j.cell.2016.03.034. Epub 2016 Apr 21.

34.

Phosphoproteome analysis of B. cinerea in response to different plant-based elicitors.

Liñeiro E, Chiva C, Cantoral JM, Sabido E, Fernández-Acero FJ.

J Proteomics. 2016 Apr 29;139:84-94. doi: 10.1016/j.jprot.2016.03.019. Epub 2016 Mar 18.

PMID:
27003611
35.

Origins of De Novo Genes in Human and Chimpanzee.

Ruiz-Orera J, Hernandez-Rodriguez J, Chiva C, Sabidó E, Kondova I, Bontrop R, Marqués-Bonet T, Albà MM.

PLoS Genet. 2015 Dec 31;11(12):e1005721. doi: 10.1371/journal.pgen.1005721. eCollection 2015 Dec.

36.

Rescuing discarded spectra: Full comprehensive analysis of a minimal proteome.

Lluch-Senar M, Mancuso FM, Climente-González H, Peña-Paz MI, Sabido E, Serrano L.

Proteomics. 2016 Feb;16(4):554-63. doi: 10.1002/pmic.201500187.

PMID:
26702875
37.

Signatures of Evolutionary Adaptation in Quantitative Trait Loci Influencing Trace Element Homeostasis in Liver.

Engelken J, Espadas G, Mancuso FM, Bonet N, Scherr AL, Jímenez-Álvarez V, Codina-Solà M, Medina-Stacey D, Spataro N, Stoneking M, Calafell F, Sabidó E, Bosch E.

Mol Biol Evol. 2016 Mar;33(3):738-54. doi: 10.1093/molbev/msv267. Epub 2015 Nov 17.

38.

The seipin complex Fld1/Ldb16 stabilizes ER-lipid droplet contact sites.

Grippa A, Buxó L, Mora G, Funaya C, Idrissi FZ, Mancuso F, Gomez R, Muntanyà J, Sabidó E, Carvalho P.

J Cell Biol. 2015 Nov 23;211(4):829-44. doi: 10.1083/jcb.201502070. Epub 2015 Nov 16.

39.

Protein-Based Classifier to Predict Conversion from Clinically Isolated Syndrome to Multiple Sclerosis.

Borràs E, Cantó E, Choi M, Maria Villar L, Álvarez-Cermeño JC, Chiva C, Montalban X, Vitek O, Comabella M, Sabidó E.

Mol Cell Proteomics. 2016 Jan;15(1):318-28. doi: 10.1074/mcp.M115.053256. Epub 2015 Nov 9.

40.

Multicenter experiment for quality control of peptide-centric LC-MS/MS analysis - A longitudinal performance assessment with nLC coupled to orbitrap MS analyzers.

Campos A, Díaz R, Martínez-Bartolomé S, Sierra J, Gallardo O, Sabidó E, López-Lucendo M, Ignacio Casal J, Pasquarello C, Scherl A, Chiva C, Borras E, Odena A, Elortza F, Azkargorta M, Ibarrola N, Canals F, Albar JP, Oliveira E.

J Proteomics. 2015 Sep 8;127(Pt B):264-74. doi: 10.1016/j.jprot.2015.05.012. Epub 2015 May 14.

PMID:
25982386
41.

Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage.

Casas C, Isus L, Herrando-Grabulosa M, Mancuso FM, Borrás E, Sabidó E, Forés J, Aloy P.

Sci Rep. 2015 Mar 18;5:9185. doi: 10.1038/srep09185.

42.

Validation of semaphorin 7A and ala-β-his-dipeptidase as biomarkers associated with the conversion from clinically isolated syndrome to multiple sclerosis.

Cantó E, Tintoré M, Villar LM, Borrás E, Alvarez-Cermeño JC, Chiva C, Sabidó E, Rovira A, Montalban X, Comabella M.

J Neuroinflammation. 2014 Nov 13;11:181. doi: 10.1186/s12974-014-0181-8.

43.

Identification of N-terminal protein acetylation and arginine methylation of the voltage-gated sodium channel in end-stage heart failure human heart.

Beltran-Alvarez P, Tarradas A, Chiva C, Pérez-Serra A, Batlle M, Pérez-Villa F, Schulte U, Sabidó E, Brugada R, Pagans S.

J Mol Cell Cardiol. 2014 Nov;76:126-9. doi: 10.1016/j.yjmcc.2014.08.014. Epub 2014 Aug 27.

PMID:
25172307
44.

TAPAS: tools to assist the targeted protein quantification of human alternative splice variants.

Yang JS, Sabidó E, Serrano L, Kiel C.

Bioinformatics. 2014 Oct 15;30(20):2989-90. doi: 10.1093/bioinformatics/btu428. Epub 2014 Jul 4.

PMID:
24996896
45.

Influence of the digestion technique, protease, and missed cleavage peptides in protein quantitation.

Chiva C, Ortega M, Sabidó E.

J Proteome Res. 2014 Sep 5;13(9):3979-86. doi: 10.1021/pr500294d. Epub 2014 Jul 28.

PMID:
24986539
46.

Profiling the secretome and extracellular proteome of the potato late blight pathogen Phytophthora infestans.

Meijer HJ, Mancuso FM, Espadas G, Seidl MF, Chiva C, Govers F, Sabidó E.

Mol Cell Proteomics. 2014 Aug;13(8):2101-13. doi: 10.1074/mcp.M113.035873. Epub 2014 May 28.

47.

The human early-life exposome (HELIX): project rationale and design.

Vrijheid M, Slama R, Robinson O, Chatzi L, Coen M, van den Hazel P, Thomsen C, Wright J, Athersuch TJ, Avellana N, Basagaña X, Brochot C, Bucchini L, Bustamante M, Carracedo A, Casas M, Estivill X, Fairley L, van Gent D, Gonzalez JR, Granum B, Gražulevičienė R, Gutzkow KB, Julvez J, Keun HC, Kogevinas M, McEachan RR, Meltzer HM, Sabidó E, Schwarze PE, Siroux V, Sunyer J, Want EJ, Zeman F, Nieuwenhuijsen MJ.

Environ Health Perspect. 2014 Jun;122(6):535-44. doi: 10.1289/ehp.1307204. Epub 2014 Mar 7.

48.

Lifelong exercise training modulates cardiac mitochondrial phosphoproteome in rats.

Ferreira R, Vitorino R, Padrão AI, Espadas G, Mancuso FM, Moreira-Gonçalves D, Castro-Sousa G, Henriques-Coelho T, Oliveira PA, Barros AS, Duarte JA, Sabidó E, Amado F.

J Proteome Res. 2014 Apr 4;13(4):2045-55. doi: 10.1021/pr4011926. Epub 2014 Mar 4.

PMID:
24467267
49.

Targeted protein quantification using sparse reference labeling.

Chang CY, Sabidó E, Aebersold R, Vitek O.

Nat Methods. 2014 Mar;11(3):301-4. doi: 10.1038/nmeth.2806. Epub 2014 Jan 19.

PMID:
24441934
50.

Quantification of ErbB network proteins in three cell types using complementary approaches identifies cell-general and cell-type-specific signaling proteins.

Kiel C, Ebhardt HA, Burnier J, Portugal C, Sabidó E, Zimmermann T, Aebersold R, Serrano L.

J Proteome Res. 2014 Jan 3;13(1):300-13. doi: 10.1021/pr400878x. Epub 2013 Dec 9.

PMID:
24313378

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