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Brain permeant and impermeant inhibitors of fatty-acid amide hydrolase synergize with the opioid analgesic morphine to suppress chemotherapy-induced neuropathic nociception without enhancing effects of morphine on gastrointestinal transit.

Slivicki RA, Saberi SA, Iyer V, Vemuri K, Makriyannis A, Hohmann AG.

J Pharmacol Exp Ther. 2018 Oct 1. pii: jpet.118.252288. doi: 10.1124/jpet.118.252288. [Epub ahead of print]

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