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Items: 23

1.

Whole body periodic acceleration in normal and reduced mucociliary clearance of conscious sheep.

Sabater JR, Sackner MA, Adams JA, Abraham WM.

PLoS One. 2019 Nov 7;14(11):e0224764. doi: 10.1371/journal.pone.0224764. eCollection 2019.

2.

Losartan Rescues Inflammation-related Mucociliary Dysfunction in Relevant Models of Cystic Fibrosis.

Kim MD, Baumlin N, Yoshida M, Polineni D, Salathe SF, David JK, Peloquin CA, Wanner A, Dennis JS, Sailland J, Whitney P, Horrigan FT, Sabater JR, Abraham WM, Salathe M.

Am J Respir Crit Care Med. 2020 Feb 1;201(3):313-324. doi: 10.1164/rccm.201905-0990OC.

PMID:
31613648
3.

Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis.

Esther CR Jr, Muhlebach MS, Ehre C, Hill DB, Wolfgang MC, Kesimer M, Ramsey KA, Markovetz MR, Garbarine IC, Forest MG, Seim I, Zorn B, Morrison CB, Delion MF, Thelin WR, Villalon D, Sabater JR, Turkovic L, Ranganathan S, Stick SM, Boucher RC.

Sci Transl Med. 2019 Apr 3;11(486). pii: eaav3488. doi: 10.1126/scitranslmed.aav3488.

4.

Evaluation of a SPLUNC1-derived peptide for the treatment of cystic fibrosis lung disease.

Terryah ST, Fellner RC, Ahmad S, Moore PJ, Reidel B, Sesma JI, Kim CS, Garland AL, Scott DW, Sabater JR, Carpenter J, Randell SH, Kesimer M, Abraham WM, Arendshorst WJ, Tarran R.

Am J Physiol Lung Cell Mol Physiol. 2018 Jan 1;314(1):L192-L205. doi: 10.1152/ajplung.00546.2016. Epub 2017 Oct 5.

5.

SPX-101 Is a Novel Epithelial Sodium Channel-targeted Therapeutic for Cystic Fibrosis That Restores Mucus Transport.

Scott DW, Walker MP, Sesma J, Wu B, Stuhlmiller TJ, Sabater JR, Abraham WM, Crowder TM, Christensen DJ, Tarran R.

Am J Respir Crit Care Med. 2017 Sep 15;196(6):734-744. doi: 10.1164/rccm.201612-2445OC.

PMID:
28481660
6.

Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion.

Tarran R, Sabater JR, Clarke TC, Tan CD, Davies CM, Liu J, Yeung A, Garland AL, Stutts MJ, Abraham WM, Phillips G, Baker WR, Wright CD, Wilbert S.

Am J Physiol Lung Cell Mol Physiol. 2013 Jun 1;304(11):L746-56. doi: 10.1152/ajplung.00292.2012. Epub 2013 Mar 29.

7.

Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease.

Coote K, Atherton-Watson HC, Sugar R, Young A, MacKenzie-Beevor A, Gosling M, Bhalay G, Bloomfield G, Dunstan A, Bridges RJ, Sabater JR, Abraham WM, Tully D, Pacoma R, Schumacher A, Harris J, Danahay H.

J Pharmacol Exp Ther. 2009 May;329(2):764-74. doi: 10.1124/jpet.108.148155. Epub 2009 Feb 3.

PMID:
19190233
8.

The porcine lung as a potential model for cystic fibrosis.

Rogers CS, Abraham WM, Brogden KA, Engelhardt JF, Fisher JT, McCray PB Jr, McLennan G, Meyerholz DK, Namati E, Ostedgaard LS, Prather RS, Sabater JR, Stoltz DA, Zabner J, Welsh MJ.

Am J Physiol Lung Cell Mol Physiol. 2008 Aug;295(2):L240-63. doi: 10.1152/ajplung.90203.2008. Epub 2008 May 16. Review.

9.

Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease.

Hirsh AJ, Zhang J, Zamurs A, Fleegle J, Thelin WR, Caldwell RA, Sabater JR, Abraham WM, Donowitz M, Cha B, Johnson KB, St George JA, Johnson MR, Boucher RC.

J Pharmacol Exp Ther. 2008 Apr;325(1):77-88. doi: 10.1124/jpet.107.130443. Epub 2008 Jan 24.

PMID:
18218832
10.

Hyaluronan blocks porcine pancreatic elastase-induced mucociliary dysfunction in allergic sheep.

Scuri M, Sabater JR, Abraham WM.

J Appl Physiol (1985). 2007 Jun;102(6):2324-31. Epub 2007 Mar 29.

11.
12.

Airway responses to aerosolized brevetoxins in an animal model of asthma.

Abraham WM, Bourdelais AJ, Sabater JR, Ahmed A, Lee TA, Serebriakov I, Baden DG.

Am J Respir Crit Care Med. 2005 Jan 1;171(1):26-34. Epub 2004 Sep 24.

13.

Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease.

Hirsh AJ, Sabater JR, Zamurs A, Smith RT, Paradiso AM, Hopkins S, Abraham WM, Boucher RC.

J Pharmacol Exp Ther. 2004 Dec;311(3):929-38. Epub 2004 Jul 23.

PMID:
15273255
14.

Montelukast prevents antigen-induced mucociliary dysfunction in sheep.

Sabater JR, Wanner A, Abraham WM.

Am J Respir Crit Care Med. 2002 Dec 1;166(11):1457-60. Epub 2002 Sep 17.

PMID:
12406819
15.

Pharmacology of INS37217 [P(1)-(uridine 5')-P(4)- (2'-deoxycytidine 5')tetraphosphate, tetrasodium salt], a next-generation P2Y(2) receptor agonist for the treatment of cystic fibrosis.

Yerxa BR, Sabater JR, Davis CW, Stutts MJ, Lang-Furr M, Picher M, Jones AC, Cowlen M, Dougherty R, Boyer J, Abraham WM, Boucher RC.

J Pharmacol Exp Ther. 2002 Sep;302(3):871-80.

PMID:
12183642
16.

Effects of unilateral bronchoconstriction on distribution of aerosols in ovine airways.

Sabater JR, Atkins ND, Wanner A, O'Riordan TG.

J Aerosol Med. 2001 Fall;14(3):369-75.

PMID:
11693849
17.

Inhaled porcine pancreatic elastase causes bronchoconstriction via a bradykinin-mediated mechanism.

Scuri M, Forteza R, Lauredo I, Sabater JR, Botvinnikova Y, Allegra L, Abraham WM.

J Appl Physiol (1985). 2000 Oct;89(4):1397-402.

18.

Aerosolization of P2Y(2)-receptor agonists enhances mucociliary clearance in sheep.

Sabater JR, Mao YM, Shaffer C, James MK, O'Riordan TG, Abraham WM.

J Appl Physiol (1985). 1999 Dec;87(6):2191-6.

19.

Selectin blockade prevents antigen-induced late bronchial responses and airway hyperresponsiveness in allergic sheep.

Abraham WM, Ahmed A, Sabater JR, Lauredo IT, Botvinnikova Y, Bjercke RJ, Hu X, Revelle BM, Kogan TP, Scott IL, Dixon RA, Yeh ET, Beck PJ.

Am J Respir Crit Care Med. 1999 Apr;159(4 Pt 1):1205-14.

PMID:
10194167
20.
21.

Mechanism of pyocyanin- and 1-hydroxyphenazine-induced lung neutrophilia in sheep airways.

Lauredo IT, Sabater JR, Ahmed A, Botvinnikova Y, Abraham WM.

J Appl Physiol (1985). 1998 Dec;85(6):2298-304.

22.

Budesonide affects allergic mucociliary dysfunction.

O'Riordan TG, Mao Y, Otero R, Lopez J, Sabater JR, Abraham WM.

J Appl Physiol (1985). 1998 Sep;85(3):1086-91.

23.

Endothelin-1 depresses tracheal mucus velocity in ovine airways via ET-A receptors.

Sabater JR, Otero R, Abraham WM, Wanner A, O'Riordan TG.

Am J Respir Crit Care Med. 1996 Aug;154(2 Pt 1):341-5.

PMID:
8756804

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