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Clonal competition within complex evolutionary hierarchies shapes AML over time.

Sandén C, Lilljebjörn H, Orsmark Pietras C, Henningsson R, Saba KH, Landberg N, Thorsson H, von Palffy S, Peña-Martinez P, Högberg C, Rissler M, Gisselsson D, Lazarevic V, Juliusson G, Ågerstam H, Fioretos T.

Nat Commun. 2020 Feb 5;11(1):579. doi: 10.1038/s41467-019-14106-0.


NTRK fusions in osteosarcoma are rare and non-functional events.

Ameline B, Saba KH, Kovac M, Magnusson L, Witt O, Bielack S, Nathrath M, Nord KH, Baumhoer D.

J Pathol Clin Res. 2020 Feb 5. doi: 10.1002/cjp2.158. [Epub ahead of print]


Expression of ESAT-6 antigen from Mycobacterium tuberculosis in broccoli: An edible plant.

Saba K, Sameeullah M, Asghar A, Gottschamel J, Latif S, Lössl AG, Mirza B, Mirza O, Waheed MT.

Biotechnol Appl Biochem. 2020 Jan 2. doi: 10.1002/bab.1867. [Epub ahead of print]


CSF Protein Level and Short-Term Prognosis in Guillain-Barré Syndrome.

Saba K, Hossieny ZS, Arnold WD, Elsheikh B, Palettas M, Kline D, Stino AM.

J Clin Neuromuscul Dis. 2019 Dec;21(2):118-119. doi: 10.1097/CND.0000000000000259. No abstract available.


External Validation and Comparison of Prostate Cancer Risk Calculators Incorporating Multiparametric Magnetic Resonance Imaging for Prediction of Clinically Significant Prostate Cancer.

Saba K, Wettstein MS, Lieger L, Hötker AM, Donati OF, Moch H, Ankerst DP, Poyet C, Sulser T, Eberli D, Mortezavi A.

J Urol. 2019 Oct 25:101097JU0000000000000622. doi: 10.1097/JU.0000000000000622. [Epub ahead of print]


Multi-cohort modeling strategies for scalable globally accessible prostate cancer risk tools.

Tolksdorf J, Kattan MW, Boorjian SA, Freedland SJ, Saba K, Poyet C, Guerrios L, De Hoedt A, Liss MA, Leach RJ, Hernandez J, Vertosick E, Vickers AJ, Ankerst DP.

BMC Med Res Methodol. 2019 Oct 15;19(1):191. doi: 10.1186/s12874-019-0839-0.


Multicenter Validation of Histopathologic Tumor Regression Grade After Neoadjuvant Chemotherapy in Muscle-invasive Bladder Carcinoma.

Voskuilen CS, Oo HZ, Genitsch V, Smit LA, Vidal A, Meneses M, Necchi A, Colecchia M, Xylinas E, Fontugne J, Sibony M, Rouprêt M, Lenfant L, Côté JF, Buser L, Saba K, Furrer MA, van der Heijden MS, Daugaard M, Black PC, van Rhijn BWG, Hendricksen K, Poyet C, Seiler R.

Am J Surg Pathol. 2019 Dec;43(12):1600-1610. doi: 10.1097/PAS.0000000000001371.


High-throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification.

Zhu Y, Weiss T, Zhang Q, Sun R, Wang B, Yi X, Wu Z, Gao H, Cai X, Ruan G, Zhu T, Xu C, Lou S, Yu X, Gillet L, Blattmann P, Saba K, Fankhauser CD, Schmid MB, Rutishauser D, Ljubicic J, Christiansen A, Fritz C, Rupp NJ, Poyet C, Rushing E, Weller M, Roth P, Haralambieva E, Hofer S, Chen C, Jochum W, Gao X, Teng X, Chen L, Zhong Q, Wild PJ, Aebersold R, Guo T.

Mol Oncol. 2019 Nov;13(11):2305-2328. doi: 10.1002/1878-0261.12570. Epub 2019 Sep 18.


Chloroplast-based inducible expression of ESAT-6 antigen for development of a plant-based vaccine against tuberculosis.

Saba K, Gottschamel J, Younus I, Syed T, Gull K, Lössl AG, Mirza B, Waheed MT.

J Biotechnol. 2019 Nov 10;305:1-10. doi: 10.1016/j.jbiotec.2019.08.016. Epub 2019 Aug 24.


Genetic profiling of a chondroblastoma-like osteosarcoma/malignant phosphaturic mesenchymal tumor of bone reveals a homozygous deletion of CDKN2A, intragenic deletion of DMD, and a targetable FN1-FGFR1 gene fusion.

Saba KH, Cornmark L, Rissler M, Fioretos T, Åström K, Haglund F, Rosenberg AE, Brosjö O, Nord KH.

Genes Chromosomes Cancer. 2019 Oct;58(10):731-736. doi: 10.1002/gcc.22764. Epub 2019 May 15.


Health Care Use Over 3 Years After Adolescent SBIRT.

Sterling S, Kline-Simon AH, Jones A, Hartman L, Saba K, Weisner C, Parthasarathy S.

Pediatrics. 2019 May;143(5). pii: e20182803. doi: 10.1542/peds.2018-2803.


Urothelial Carcinoma in Bladder Diverticula: A Multicenter Analysis of Characteristics and Clinical Outcomes.

Voskuilen CS, Seiler R, Rink M, Poyet C, Noon AP, Roghmann F, Necchi A, Aziz A, Lavollé A, Young MJ, Marks P, Saba K, van Rhijn BWG, Fransen van de Putte EE, Ablat J, Black PC, Sosnowski R, Dobruch J, Kumar P, Jallad S, Catto JWF, Xylinas E, Hendricksen K; Young Academic Urologists’ Working Group on Urothelial Carcinoma of the European Association of Urology.

Eur Urol Focus. 2018 Dec 14. pii: S2405-4569(18)30382-1. doi: 10.1016/j.euf.2018.12.002. [Epub ahead of print]


Prognostic value of unifocal and multifocal positive surgical margins in a large series of robot-assisted radical prostatectomy for prostate cancer.

Keller EX, Bachofner J, Britschgi AJ, Saba K, Mortezavi A, Kaufmann B, Fankhauser CD, Wild P, Sulser T, Hermanns T, Eberli D, Poyet C.

World J Urol. 2019 Sep;37(9):1837-1844. doi: 10.1007/s00345-018-2578-y. Epub 2018 Dec 5.


Comparison Of Two Intracanal Medicaments In Resolution Of Apical Radiolucency.

Riaz A, Maxood A, Abdullah S, Saba K, Din SU, Zahid S.

J Ayub Med Coll Abbottabad. 2018 Jul-Sep;30(3):320-324.


Interplay of N acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs.

Ali T, Mushtaq I, Maryam S, Farhan A, Saba K, Jan MI, Sultan A, Anees M, Duygu B, Hamera S, Tabassum S, Javed Q, da Costa Martins PA, Murtaza I.

Arch Biochem Biophys. 2019 Jan;661:56-65. doi: 10.1016/ Epub 2018 Nov 12.


Comparison of frequency of pain in root canal treatment using sodium hypochlorite and chlorhexidine as root canal irrigants.

Saba K, Maxood A, Abdullah S, Riaz A, Uddin S.

J Pak Med Assoc. 2018 Sep;68(9):1334-1338.


Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkers.

Guo T, Li L, Zhong Q, Rupp NJ, Charmpi K, Wong CE, Wagner U, Rueschoff JH, Jochum W, Fankhauser CD, Saba K, Poyet C, Wild PJ, Aebersold R, Beyer A.

Life Sci Alliance. 2018 May 29;1(2). pii: e201800042. doi: 10.26508/lsa.201800042.


Comparison Of Frequency Of Post Operative Sensitivity In Amalgam Restorations Using Copal Varnish And Dentin Adhesive Liner.

Saba K, Maxood A, Abdullah S, Riaz A, Din SU.

J Ayub Med Coll Abbottabad. 2018 Apr-Jun;30(2):163-166.


Amalaki Rasayana improved memory and neuronal metabolic activity in AbPP-PS1 mouse model of Alzheimer's disease.

Tiwari V, Saba K, Veeraiah P, Jose J, Lakhotia SC, Patel AB.

J Biosci. 2017 Sep;42(3):363-371.


Energetics of Excitatory and Inhibitory Neurotransmission in Aluminum Chloride Model of Alzheimer's Disease: Reversal of Behavioral and Metabolic Deficits by Rasa Sindoor.

Saba K, Rajnala N, Veeraiah P, Tiwari V, Rana RK, Lakhotia SC, Patel AB.

Front Mol Neurosci. 2017 Oct 17;10:323. doi: 10.3389/fnmol.2017.00323. eCollection 2017.


Venous thromboembolism in adult elective spinal surgery: a tertiary centre review of 2181 patients.

Fawi HMT, Saba K, Cunningham A, Masud S, Lewis M, Hossain M, Chopra I, Ahuja S.

Bone Joint J. 2017 Sep;99-B(9):1204-1209. doi: 10.1302/0301-620X.99B9.BJJ-2016-1193.R2.


Prevalence and causes of abnormal PSA recovery.

Lautenbach N, Müntener M, Zanoni P, Saleh L, Saba K, Umbehr M, Velagapudi S, Hof D, Sulser T, Wild PJ, von Eckardstein A, Poyet C.

Clin Chem Lab Med. 2018 Jan 26;56(2):341-349. doi: 10.1515/cclm-2017-0246.


Loss of the tumour suppressor gene AIP mediates the browning of human brown fat tumours.

Magnusson L, Hansen N, Saba KH, Nilsson J, Fioretos T, Rissler P, Nord KH.

J Pathol. 2017 Oct;243(2):160-164. doi: 10.1002/path.4945. Epub 2017 Aug 29.


Increased astroglial activity and reduced neuronal function across brain in AβPP-PS1 mouse model of Alzheimer's disease.

Patel AB, Tiwari V, Veeraiah P, Saba K.

J Cereb Blood Flow Metab. 2018 Jul;38(7):1213-1226. doi: 10.1177/0271678X17709463. Epub 2017 Jun 6.


A curated collection of tissue microarray images and clinical outcome data of prostate cancer patients.

Zhong Q, Guo T, Rechsteiner M, Rüschoff JH, Rupp N, Fankhauser C, Saba K, Mortezavi A, Poyet C, Hermanns T, Zhu Y, Moch H, Aebersold R, Wild PJ.

Sci Data. 2017 Mar 14;4:170014. doi: 10.1038/sdata.2017.14.


Prognostic Role of Preoperative Serum Lipid Levels in Patients Undergoing Radical Prostatectomy for Clinically Localized Prostate Cancer.

Wettstein MS, Saba K, Umbehr MH, Murtola TJ, Fankhauser CD, Adank JP, Hofmann M, Sulser T, Hermanns T, Moch H, Wild P, Poyet C.

Prostate. 2017 Apr;77(5):549-556. doi: 10.1002/pros.23296. Epub 2017 Jan 17.


External Evaluation of a Novel Prostate Cancer Risk Calculator (ProstateCheck) Based on Data from the Swiss Arm of the ERSPC.

Poyet C, Wettstein MS, Lundon DJ, Bhindi B, Kulkarni GS, Saba K, Sulser T, Vickers AJ, Hermanns T.

J Urol. 2016 Nov;196(5):1402-1407. doi: 10.1016/j.juro.2016.05.081. Epub 2016 May 14.


A designed recombinant fusion protein for targeted delivery of siRNA to the mouse brain.

Haroon MM, Dar GH, Jeyalakshmi D, Venkatraman U, Saba K, Rangaraj N, Patel AB, Gopal V.

J Control Release. 2016 Apr 28;228:120-131. doi: 10.1016/j.jconrel.2016.03.007. Epub 2016 Mar 4.


Clinical impact of prostate biopsy undergrading in an academic and community setting.

Mortezavi A, Keller EX, Poyet C, Hermanns T, Saba K, Randazzo M, Fankhauser CD, Wild PJ, Moch H, Sulser T, Eberli D.

World J Urol. 2016 Oct;34(10):1481-90. doi: 10.1007/s00345-016-1788-4. Epub 2016 Mar 1.


Use of supravital toluidine blue staining to improve the efficiency of fine-needle aspiration cytology reporting in comparison to papanicolaou stain.

Saba K, Niazi S, Bukhari MH, Imam SF.

Pak J Med Sci. 2015 Sep-Oct;31(5):1146-51. doi: 10.12669/pjms.315.8411.


Bone mineral density and diet of teachers of College of Home Economics at Lahore.

Javed Z, Imam SF, Imam N, Saba K, Bukhari MH.

Pak J Med Sci. 2015 Jul-Aug;31(4):970-4. doi: 10.12669/pjms.314.8433.


Frequency of placenta previa in previously scarred and non scarred uterus.

Majeed T, Waheed F, Mahmood Z, Saba K, Mahmood H, Bukhari MH.

Pak J Med Sci. 2015 Mar-Apr;31(2):360-3. doi: 10.12669/pjms.312.6509.


Acute abdominal pain accompanied by high creatinine in a female patient with schizophrenia.

Mauerhofer E, Lüscher M, Poyet C, Saba K, Andreisek G, Sulser T, Mortezavi A.

Urology. 2015 Mar;85(3):495-8. doi: 10.1016/j.urology.2014.10.034. Epub 2014 Nov 4. No abstract available.


Frequency of HER2/neu overexpression in adenocarcinoma of the gastrointestinal system.

Farzand S, Siddique T, Saba K, Bukhari MH.

World J Gastroenterol. 2014 May 21;20(19):5889-96. doi: 10.3748/wjg.v20.i19.5889.


Primary isolated hepatic tuberculosis.

Farooq Sheikh AS, Qureshi IH, Saba K, Bukhari MH.

J Coll Physicians Surg Pak. 2013 May;23(5):359-61. doi: 05.2013/JCPSP.359361.


Clinicopathological importance of Papanicolaou smears for the diagnosis of premalignant and malignant lesions of the cervix.

Bukhari MH, Saba K, Qamar S, Majeed MM, Niazi S, Naeem S.

J Cytol. 2012 Jan;29(1):20-5. doi: 10.4103/0970-9371.93213.


Increased peanut-specific IgA levels in saliva correlate with food challenge outcomes after peanut sublingual immunotherapy.

Kulis M, Saba K, Kim EH, Bird JA, Kamilaris N, Vickery BP, Staats H, Burks AW.

J Allergy Clin Immunol. 2012 Apr;129(4):1159-62. doi: 10.1016/j.jaci.2011.11.045. Epub 2012 Jan 10. No abstract available.


The utility of questionnaires in cognitive and functional assessment in Alzheimer's disease.

Aziz VM, Yagoub J, Saba K, Asaad M.

Int Psychogeriatr. 2011 Mar;23(2):333-4. doi: 10.1017/S1041610210001559. Epub 2010 Aug 18. No abstract available.


Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells.

Denda-Nagai K, Aida S, Saba K, Suzuki K, Moriyama S, Oo-Puthinan S, Tsuiji M, Morikawa A, Kumamoto Y, Sugiura D, Kudo A, Akimoto Y, Kawakami H, Bovin NV, Irimura T.

J Biol Chem. 2010 Jun 18;285(25):19193-204. doi: 10.1074/jbc.M110.113613. Epub 2010 Mar 19.


A C-type lectin MGL1/CD301a plays an anti-inflammatory role in murine experimental colitis.

Saba K, Denda-Nagai K, Irimura T.

Am J Pathol. 2009 Jan;174(1):144-52. doi: 10.2353/ajpath.2009.080235. Epub 2008 Dec 18.


[Recent topics on immune regulation by C-type lectin].

Saba K, Irimura T.

Tanpakushitsu Kakusan Koso. 2008 Sep;53(12 Suppl):1625-9. Review. Japanese. No abstract available.


Transforming growth factor-beta 1 gene polymorphisms and expression in the blood of prostate cancer patients.

Faria PC, Saba K, Neves AF, Cordeiro ER, Marangoni K, Freitas DG, Goulart LR.

Cancer Invest. 2007 Dec;25(8):726-32.


Directed differentiation of embryonic stem cells into bladder tissue.

Oottamasathien S, Wang Y, Williams K, Franco OE, Wills ML, Thomas JC, Saba K, Sharif-Afshar AR, Makari JH, Bhowmick NA, DeMarco RT, Hipkens S, Magnuson M, Brock JW 3rd, Hayward SW, Pope JC 4th, Matusik RJ.

Dev Biol. 2007 Apr 15;304(2):556-66. Epub 2007 Jan 12.


Bladder tissue formation from cultured bladder urothelium.

Oottamasathien S, Williams K, Franco OE, Thomas JC, Saba K, Bhowmick NA, Staack A, Demarco RT, Brock JW 3rd, Hayward SW, Pope JC 4th.

Dev Dyn. 2006 Oct;235(10):2795-801.


DNA microarray analysis of Methanosarcina mazei Gö1 reveals adaptation to different methanogenic substrates.

Hovey R, Lentes S, Ehrenreich A, Salmon K, Saba K, Gottschalk G, Gunsalus RP, Deppenmeier U.

Mol Genet Genomics. 2005 May;273(3):225-39. Epub 2005 Apr 7.


Effective application of monitoring information: the case of San Francisco Bay.

Hoenicke R, Davis JA, Gunther A, Mumley TE, Abu-Saba K, Taberski K.

Environ Monit Assess. 2003 Jan-Feb;81(1-3):15-25.


Implantofix vascular access system: an experience with 19 patients.

Alpeter DM Jr, Welling RE, Saba KA, Mahalingam K, Arbaugh J Jr.

J Surg Oncol. 1988 Nov;39(3):210-2.


Ruptured actinomycotic aneurysm of the splenic artery: a case report of successful resection.

Kakkasseril J, Cabanas V, Saba K.

Surgery. 1983 Apr;93(4):595-7. No abstract available.


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