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Items: 1 to 50 of 192

1.

Unraveling the β-amyloid clearance by astrocytes: Involvement of metabotropic glutamate receptor 3, sAPPα, and class-A scavenger receptor.

Durand D, Turati J, Rudi MJ, Ramírez D, Saba J, Caruso C, Carniglia L, von Bernhardi R, Lasaga M.

Neurochem Int. 2019 Dec;131:104547. doi: 10.1016/j.neuint.2019.104547. Epub 2019 Sep 16.

PMID:
31536785
2.

Ability to pay for medication: a clustering analysis of 1404 patients with the Patient Financial Eligibility Tool.

Audureau E, Besson MH, Nofal A, Jayasundera R, Saba J, Ladner J.

J Comp Eff Res. 2019 Sep;8(12):969-977. doi: 10.2217/cer-2019-0063. Epub 2019 Jul 12.

3.

Correction to: Sphingadienes show therapeutic efficacy in neuroblastoma in vitro and in vivo by targeting the AKT signaling pathway.

Zhao P, Aguilar AE, Lee JY, Paul LA, Suh JH, Puri L, Zhang M, Beckstead J, Witkowski A, Ryan RO, Saba JD.

Invest New Drugs. 2019 Dec;37(6):1309. doi: 10.1007/s10637-019-00772-w.

PMID:
31032525
4.

Tumor Necrosis Factor Receptor-1 Associated Periodic Syndrome: Case Report and Review of an Auto-inflammatory Disorder.

Quintero J, Saba J, Garcia C.

Cureus. 2019 Jan 19;11(1):e3916. doi: 10.7759/cureus.3916.

5.

Fasciitis and Streptococcal Toxic-shock Syndrome: The Importance of Early Diagnosis and Surgical Management.

Abrego MO, Saba JES, Halliburton C, Taype DRE, Sancineto CF.

J Orthop Case Rep. 2018 Sep-Oct;8(5):57-60. doi: 10.13107/jocr.2250-0685.1212.

6.

NDP-MSH reduces oxidative damage induced by palmitic acid in primary astrocytes.

Ramírez D, Saba J, Turati J, Carniglia L, Imsen M, Mohn C, Scimonelli T, Durand D, Caruso C, Lasaga M.

J Neuroendocrinol. 2019 Feb;31(2):e12673. doi: 10.1111/jne.12673. Epub 2019 Feb 20.

PMID:
30712280
7.

Willingness to pay for medical treatments in chronic diseases: a multicountry survey of patients and physicians.

Audureau E, Davis B, Besson MH, Saba J, Ladner J.

J Comp Eff Res. 2019 Apr;8(5):357-369. doi: 10.2217/cer-2018-0106. Epub 2019 Jan 16.

8.

Fifty years of lyase and a moment of truth: sphingosine phosphate lyase from discovery to disease.

Saba JD.

J Lipid Res. 2019 Mar;60(3):456-463. doi: 10.1194/jlr.S091181. Epub 2019 Jan 11.

PMID:
30635364
9.

The elemental mechanism of transcriptional pausing.

Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R.

Elife. 2019 Jan 8;8. pii: e40981. doi: 10.7554/eLife.40981.

10.

Formant priority channel selection for an "n-of-m" sound processing strategy for cochlear implants.

Saba JN, Ali H, Hansen JHL.

J Acoust Soc Am. 2018 Dec;144(6):3371. doi: 10.1121/1.5080257.

PMID:
30599685
11.

Melanocortin 4 receptor activation protects striatal neurons and glial cells from 3-nitropropionic acid toxicity.

Saba J, Carniglia L, Ramírez D, Turati J, Imsen M, Durand D, Lasaga M, Caruso C.

Mol Cell Neurosci. 2019 Jan;94:41-51. doi: 10.1016/j.mcn.2018.12.002. Epub 2018 Dec 4.

PMID:
30529228
12.

Sphingosine phosphate lyase insufficiency syndrome (SPLIS): A novel inborn error of sphingolipid metabolism.

Choi YJ, Saba JD.

Adv Biol Regul. 2019 Jan;71:128-140. doi: 10.1016/j.jbior.2018.09.004. Epub 2018 Sep 25. Review.

PMID:
30274713
13.

Hepatitis C in Lebanon: the burden of the disease and the value of comprehensive screening and treatment.

Abou Rached A, Abou Kheir S, Saba J, Assaf S, Kassis G, Sanchez Gonzalez Y, Ethgen O.

Hepat Med. 2018 Aug 28;10:73-85. doi: 10.2147/HMER.S160351. eCollection 2018.

14.

Obstructive Giant Inflammatory Polyposis: Is It Related to the Severity or the Duration of the Inflammatory Bowel Disease? Two Case Reports.

Abou Rached A, Saba J, El Masri L, Nakhoul M, Razzouk C.

Case Rep Gastrointest Med. 2018 Jun 10;2018:3251549. doi: 10.1155/2018/3251549. eCollection 2018.

15.

Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators.

Kang JY, Mooney RA, Nedialkov Y, Saba J, Mishanina TV, Artsimovitch I, Landick R, Darst SA.

Cell. 2018 Jun 14;173(7):1650-1662.e14. doi: 10.1016/j.cell.2018.05.017. Epub 2018 Jun 7.

16.

Astrocyte truncated tropomyosin receptor kinase B mediates brain-derived neurotrophic factor anti-apoptotic effect leading to neuroprotection.

Saba J, Turati J, Ramírez D, Carniglia L, Durand D, Lasaga M, Caruso C.

J Neurochem. 2018 Sep;146(6):686-702. doi: 10.1111/jnc.14476. Epub 2018 Aug 9.

17.

Sphingosine-1-Phosphate Signaling and Metabolism Gene Signature in Pediatric Inflammatory Bowel Disease: A Matched-case Control Pilot Study.

Suh JH, Degagné É, Gleghorn EE, Setty M, Rodriguez A, Park KT, Verstraete SG, Heyman MB, Patel AS, Irek M, Gildengorin GL, Hubbard NE, Borowsky AD, Saba JD.

Inflamm Bowel Dis. 2018 May 18;24(6):1321-1334. doi: 10.1093/ibd/izy007.

18.

Sphingadienes show therapeutic efficacy in neuroblastoma in vitro and in vivo by targeting the AKT signaling pathway.

Zhao P, Aguilar AE, Lee JY, Paul LA, Suh JH, Puri L, Zhang M, Beckstead J, Witkowski A, Ryan RO, Saba JD.

Invest New Drugs. 2018 Oct;36(5):743-754. doi: 10.1007/s10637-017-0558-5. Epub 2018 Jan 16. Erratum in: Invest New Drugs. 2019 Dec;37(6):1309.

19.

S1P Lyase Regulation of Thymic Egress and Oncogenic Inflammatory Signaling.

Kumar A, Zamora-Pineda J, Degagné E, Saba JD.

Mediators Inflamm. 2017;2017:7685142. doi: 10.1155/2017/7685142. Epub 2017 Dec 3. Review.

20.

Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity.

Hahn C, Tyka K, Saba JD, Lenzen S, Gurgul-Convey E.

J Biol Chem. 2017 Dec 8;292(49):20292-20304. doi: 10.1074/jbc.M117.814491. Epub 2017 Oct 25.

21.

Treatment-seeking patterns for malaria in pharmacies in five sub-Saharan African countries.

Ladner J, Davis B, Audureau E, Saba J.

Malar J. 2017 Aug 29;16(1):353. doi: 10.1186/s12936-017-1997-3.

22.

Long-term weight loss in laparoscopic sleeve gastrectomy.

Sepúlveda M, Alamo M, Saba J, Astorga C, Lynch R, Guzmán H.

Surg Obes Relat Dis. 2017 Oct;13(10):1676-1681. doi: 10.1016/j.soard.2017.07.017. Epub 2017 Jul 25.

PMID:
28807556
23.

An LC/MS/MS method for quantitation of chemopreventive sphingadienes in food products and biological samples.

Suh JH, Makarova AM, Gomez JM, Paul LA, Saba JD.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:292-299. doi: 10.1016/j.jchromb.2017.07.040. Epub 2017 Jul 24.

24.

Obinutuzumab-induced serum sickness following salvage therapy for chronic lymphocytic leukemia.

Saba J, Logan AC.

Clin Case Rep. 2017 Apr 24;5(6):891-893. doi: 10.1002/ccr3.969. eCollection 2017 Jun.

25.

Prevalence of hepatitis C virus genotypes and subtypes in Lebanese population and major high risk groups.

Abou Rached A, Yaghi C, Khalil L, Saba J, Ammar W.

Arab J Gastroenterol. 2017 Jun;18(2):114-117. doi: 10.1016/j.ajg.2017.05.001. Epub 2017 Jun 1.

PMID:
28579342
26.

SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production.

Mitroi DN, Karunakaran I, Gräler M, Saba JD, Ehninger D, Ledesma MD, van Echten-Deckert G.

Autophagy. 2017 May 4;13(5):885-899. doi: 10.1080/15548627.2017.1291471.

27.

Amyloid-beta neurotoxicity and clearance are both regulated by glial group II metabotropic glutamate receptors.

Durand D, Carniglia L, Turati J, Ramírez D, Saba J, Caruso C, Lasaga M.

Neuropharmacology. 2017 Sep 1;123:274-286. doi: 10.1016/j.neuropharm.2017.05.008. Epub 2017 May 8.

PMID:
28495373
28.

In-depth analyses of native N-linked glycans facilitated by high-performance anion exchange chromatography-pulsed amperometric detection coupled to mass spectrometry.

Szabo Z, Thayer JR, Agroskin Y, Lin S, Liu Y, Srinivasan K, Saba J, Viner R, Huhmer A, Rohrer J, Reusch D, Harfouche R, Khan SH, Pohl C.

Anal Bioanal Chem. 2017 May;409(12):3089-3101. doi: 10.1007/s00216-017-0248-3. Epub 2017 Mar 9.

PMID:
28280844
29.

Societal impact of dengue outbreaks: Stakeholder perceptions and related implications. A qualitative study in Brazil, 2015.

Ladner J, Rodrigues M, Davis B, Besson MH, Audureau E, Saba J.

PLoS Negl Trop Dis. 2017 Mar 9;11(3):e0005366. doi: 10.1371/journal.pntd.0005366. eCollection 2017 Mar.

30.

Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency.

Lovric S, Goncalves S, Gee HY, Oskouian B, Srinivas H, Choi WI, Shril S, Ashraf S, Tan W, Rao J, Airik M, Schapiro D, Braun DA, Sadowski CE, Widmeier E, Jobst-Schwan T, Schmidt JM, Girik V, Capitani G, Suh JH, Lachaussée N, Arrondel C, Patat J, Gribouval O, Furlano M, Boyer O, Schmitt A, Vuiblet V, Hashmi S, Wilcken R, Bernier FP, Innes AM, Parboosingh JS, Lamont RE, Midgley JP, Wright N, Majewski J, Zenker M, Schaefer F, Kuss N, Greil J, Giese T, Schwarz K, Catheline V, Schanze D, Franke I, Sznajer Y, Truant AS, Adams B, Désir J, Biemann R, Pei Y, Ars E, Lloberas N, Madrid A, Dharnidharka VR, Connolly AM, Willing MC, Cooper MA, Lifton RP, Simons M, Riezman H, Antignac C, Saba JD, Hildebrandt F.

J Clin Invest. 2017 Mar 1;127(3):912-928. doi: 10.1172/JCI89626. Epub 2017 Feb 6.

31.

Neuropeptides and Microglial Activation in Inflammation, Pain, and Neurodegenerative Diseases.

Carniglia L, Ramírez D, Durand D, Saba J, Turati J, Caruso C, Scimonelli TN, Lasaga M.

Mediators Inflamm. 2017;2017:5048616. doi: 10.1155/2017/5048616. Epub 2017 Jan 5. Review.

32.

The low down on sphingosine-1-phosphate lyase as a regulator of thymic egress.

Saba JD.

J Immunol Sci. 2017;1(1):1-8. doi: 10.29245/2578-3009/2018/1.1103. Epub 2017 Dec 6.

33.

An ice sheet model validation framework for the Greenland ice sheet.

Price SF, Hoffman MJ, Bonin JA, Howat IM, Neumann T, Saba J, Tezaur I, Guerber J, Chambers DP, Evans KJ, Kennedy JH, Lenaerts J, Lipscomb WH, Perego M, Salinger AG, Tuminaro RS, van den Broeke MR, Nowicki SMJ.

Geosci Model Dev. 2017;10(1):255-270. doi: 10.5194/gmd-10-255-2017. Epub 2017 Jan 17.

34.

In vitro effects of dental cements on hard and soft tissues associated with dental implants.

Rodriguez LC, Saba JN, Chung KH, Wadhwani C, Rodrigues DC.

J Prosthet Dent. 2017 Jul;118(1):31-35. doi: 10.1016/j.prosdent.2016.10.002. Epub 2016 Dec 4.

PMID:
27927285
35.

Sphingosine 1-phosphate lyase ablation disrupts presynaptic architecture and function via an ubiquitin- proteasome mediated mechanism.

Mitroi DN, Deutschmann AU, Raucamp M, Karunakaran I, Glebov K, Hans M, Walter J, Saba J, Gräler M, Ehninger D, Sopova E, Shupliakov O, Swandulla D, van Echten-Deckert G.

Sci Rep. 2016 Nov 24;6:37064. doi: 10.1038/srep37064.

36.

Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress.

Zamora-Pineda J, Kumar A, Suh JH, Zhang M, Saba JD.

J Exp Med. 2016 Nov 14;213(12):2773-2791. Epub 2016 Oct 17.

37.

Experiences and lessons learned from 29 HPV vaccination programs implemented in 19 low and middle-income countries, 2009-2014.

Ladner J, Besson MH, Audureau E, Rodrigues M, Saba J.

BMC Health Serv Res. 2016 Oct 13;16(1):575.

38.

Quantitative LC-MS/MS Glycomic Analysis of Biological Samples Using AminoxyTMT.

Zhou S, Hu Y, Veillon L, Snovida SI, Rogers JC, Saba J, Mechref Y.

Anal Chem. 2016 Aug 2;88(15):7515-22. doi: 10.1021/acs.analchem.6b00465. Epub 2016 Jul 19.

39.

[Nle4, D-Phe7]-α-MSH Inhibits Toll-Like Receptor (TLR)2- and TLR4-Induced Microglial Activation and Promotes a M2-Like Phenotype.

Carniglia L, Ramírez D, Durand D, Saba J, Caruso C, Lasaga M.

PLoS One. 2016 Jun 30;11(6):e0158564. doi: 10.1371/journal.pone.0158564. eCollection 2016.

40.

A finite element analysis of novel vented dental abutment geometries for cement-retained crown restorations.

Rodriguez LC, Saba JN, Meyer CA, Chung KH, Wadhwani C, Rodrigues DC.

Clin Exp Dent Res. 2016 Jun 14;2(2):136-145. doi: 10.1002/cre2.33. eCollection 2016 Nov.

41.

Epidemiology of hepatitis B and hepatitis C in Lebanon.

Abou Rached A, Abou Kheir S, Saba J, Ammar W.

Arab J Gastroenterol. 2016 Mar;17(1):29-33. doi: 10.1016/j.ajg.2016.01.002. Epub 2016 Mar 28.

PMID:
27032492
42.
43.

MicroRNA abundance is altered in synaptoneurosomes during prion disease.

Boese AS, Saba R, Campbell K, Majer A, Medina S, Burton L, Booth TF, Chong P, Westmacott G, Dutta SM, Saba JA, Booth SA.

Mol Cell Neurosci. 2016 Mar;71:13-24. doi: 10.1016/j.mcn.2015.12.001. Epub 2015 Dec 4.

44.

A facile stable-isotope dilution method for determination of sphingosine phosphate lyase activity.

Suh JH, Eltanawy A, Rangan A, Saba JD.

Chem Phys Lipids. 2016 Jan;194:101-9. doi: 10.1016/j.chemphyslip.2015.09.006. Epub 2015 Sep 25.

45.

Performance of HIV Prevention of Mother-To-Child Transmission Programs in Sub-Saharan Africa: Longitudinal Assessment of 64 Nevirapine-Based Programs Implemented in 25 Countries, 2000-2011.

Ladner J, Besson MH, Rodrigues M, Saba J, Audureau E.

PLoS One. 2015 Jun 22;10(6):e0130103. doi: 10.1371/journal.pone.0130103. eCollection 2015.

46.

Automating mass spectrometry-based quantitative glycomics using aminoxy tandem mass tag reagents with SimGlycan.

Meitei NS, Apte A, Snovida SI, Rogers JC, Saba J.

J Proteomics. 2015 Sep 8;127(Pt A):211-22. doi: 10.1016/j.jprot.2015.05.015. Epub 2015 May 21.

PMID:
26003531
47.

A B cell-dependent mechanism restrains T cell transendothelial migration.

Saba JD.

Nat Med. 2015 May;21(5):424-6. doi: 10.1038/nm.3858. No abstract available.

48.

Melanocortin 4 receptor activates ERK-cFos pathway to increase brain-derived neurotrophic factor expression in rat astrocytes and hypothalamus.

Ramírez D, Saba J, Carniglia L, Durand D, Lasaga M, Caruso C.

Mol Cell Endocrinol. 2015 Aug 15;411:28-37. doi: 10.1016/j.mce.2015.04.008. Epub 2015 Apr 16.

PMID:
25892444
49.

Regulation of Immune Cell Migration by Sphingosine-1-Phosphate.

Kumar A, Saba JD.

Cell Mol Biol (OMICS). 2015;61(2). pii: 121. Epub 2015 Dec 31.

50.

Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs.

Degagné E, Pandurangan A, Bandhuvula P, Kumar A, Eltanawy A, Zhang M, Yoshinaga Y, Nefedov M, de Jong PJ, Fong LG, Young SG, Bittman R, Ahmedi Y, Saba JD.

J Clin Invest. 2014 Dec;124(12):5368-84. doi: 10.1172/JCI74188. Epub 2014 Oct 27.

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