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Microscale ecology regulates particulate organic matter turnover in model marine microbial communities.

Enke TN, Leventhal GE, Metzger M, Saavedra JT, Cordero OX.

Nat Commun. 2018 Jul 16;9(1):2743. doi: 10.1038/s41467-018-05159-8.


Discriminatory Power of Women's Handball Game-Related Statistics at the Olympic Games (2004-2016).

Saavedra JM, Þorgeirsson S, Chang M, Kristjánsdóttir H, García-Hermoso A.

J Hum Kinet. 2018 Jun 13;62:221-229. doi: 10.1515/hukin-2017-0172. eCollection 2018 Jun.


Effects of Rule Changes on Game-Related Statistics in Men's Water Polo Matches.

Madera J, Tella V, Saavedra JM.

Sports (Basel). 2017 Nov 1;5(4). pii: E84. doi: 10.3390/sports5040084.


Isolation, Functional Characterization and Transmissibility of p3PS10, a Multidrug Resistance Plasmid of the Fish Pathogen Piscirickettsia salmonis.

Saavedra J, Grandón M, Villalobos-González J, Bohle H, Bustos P, Mancilla M.

Front Microbiol. 2018 May 8;9:923. doi: 10.3389/fmicb.2018.00923. eCollection 2018.


Relevance of Local Flexibility Near the Active Site for Enzymatic Catalysis: Biochemical Characterization and Engineering of Cellulase Cel5A From Bacillus agaradherans.

Saavedra JM, Azócar MA, Rodríguez V, Ramírez-Sarmiento CA, Andrews BA, Asenjo JA, Parra LP.

Biotechnol J. 2018 Mar 25:e1700669. doi: 10.1002/biot.201700669. [Epub ahead of print]


Examination of Factors Explaining Coaching Strategy and Training Methodology as Correlates of Potential Doping Behavior in High-Level Swimming.

Liposek S, Zenic N, Saavedra JM, Sekulic D, Rodek J, Marinsek M, Sajber D.

J Sports Sci Med. 2018 Mar 1;17(1):82-91. eCollection 2018 Mar.


CO Oxidation Kinetics over Au/TiO2 and Au/Al2O3 Catalysts: Evidence for a Common Water-Assisted Mechanism.

Saavedra J, Pursell CJ, Chandler BD.

J Am Chem Soc. 2018 Mar 14;140(10):3712-3723. doi: 10.1021/jacs.7b12758. Epub 2018 Mar 5.


The Intention to be Physically Active in Sedentary Obese Children: A Longitudinal Study.

García-Hermoso A, Saavedra JM, Escalante Y, Domínguez AM.

Behav Sci (Basel). 2018 Jan 11;8(1). pii: E9. doi: 10.3390/bs8010009.


The mutagenesis of a type IV secretion system locus of Piscirickettsia salmonis leads to the attenuation of the pathogen in Atlantic salmon, Salmo salar.

Mancilla M, Saavedra J, Grandón M, Tapia E, Navas E, Grothusen H, Bustos P.

J Fish Dis. 2018 Apr;41(4):625-634. doi: 10.1111/jfd.12762. Epub 2017 Dec 18.


Cytokine and autoantibody clusters interaction in systemic lupus erythematosus.

Pacheco Y, Barahona-Correa J, Monsalve DM, Acosta-Ampudia Y, Rojas M, Rodríguez Y, Saavedra J, Rodríguez-Jiménez M, Mantilla RD, Ramírez-Santana C, Molano-González N, Anaya JM.

J Transl Med. 2017 Nov 25;15(1):239. doi: 10.1186/s12967-017-1345-y.


Effects of Exercise on Depression and Anxiety. A Comparison to Transdiagnostic Cognitive Behavioral Therapy.

Ólafsdóttir KB, Kristjánsdóttir H, Saavedra JM.

Community Ment Health J. 2017 Nov 22. doi: 10.1007/s10597-017-0213-9. [Epub ahead of print]


Associations between the duration of active commuting to school and academic achievement in rural Chilean adolescents.

García-Hermoso A, Saavedra JM, Olloquequi J, Ramírez-Vélez R.

Environ Health Prev Med. 2017 Apr 4;22(1):31. doi: 10.1186/s12199-017-0628-5.


Temporal Changes in Cortical and Hippocampal Expression of Genes Important for Brain Glucose Metabolism Following Controlled Cortical Impact Injury in Mice.

Zhou J, Burns MP, Huynh L, Villapol S, Taub DD, Saavedra JM, Blackman MR.

Front Endocrinol (Lausanne). 2017 Sep 11;8:231. doi: 10.3389/fendo.2017.00231. eCollection 2017.


In vitro asymbiotic germination for micropropagation of the recalcitrant terrestrial orchid Chloraea crispa (Orchidaceae).

Quiroz K, Saavedra J, Vogel H, Verdugo G, Caligari PDS, García-Gonzáles R.

Appl Plant Sci. 2017 Aug 29;5(8). pii: apps.1600142. doi: 10.3732/apps.1600142. eCollection 2017 Aug.


Angiotensin II AT2 Receptors Contribute to Regulate the Sympathoadrenal and Hormonal Reaction to Stress Stimuli.

Saavedra JM, Armando I.

Cell Mol Neurobiol. 2018 Jan;38(1):85-108. doi: 10.1007/s10571-017-0533-x. Epub 2017 Sep 7. Review.


Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity.

Canedo-Marroquín G, Acevedo-Acevedo O, Rey-Jurado E, Saavedra JM, Lay MK, Bueno SM, Riedel CA, Kalergis AM.

Front Cell Infect Microbiol. 2017 Aug 16;7:367. doi: 10.3389/fcimb.2017.00367. eCollection 2017. Review.


Intrinsic Plasmon-Phonon Interactions in Highly Doped Graphene: A Near-Field Imaging Study.

Bezares FJ, Sanctis A, Saavedra JRM, Woessner A, Alonso-González P, Amenabar I, Chen J, Bointon TH, Dai S, Fogler MM, Basov DN, Hillenbrand R, Craciun MF, García de Abajo FJ, Russo S, Koppens FHL.

Nano Lett. 2017 Oct 11;17(10):5908-5913. doi: 10.1021/acs.nanolett.7b01603. Epub 2017 Sep 5.


Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions.

Wang Y, Ruan W, Mi J, Xu J, Wang H, Cao Z, Saavedra JM, Zhang L, Lin H, Pang T.

Brain Behav Immun. 2018 Jan;67:101-117. doi: 10.1016/j.bbi.2017.08.006. Epub 2017 Aug 9.


A Dual AMPK/Nrf2 Activator Reduces Brain Inflammation After Stroke by Enhancing Microglia M2 Polarization.

Wang Y, Huang Y, Xu Y, Ruan W, Wang H, Zhang Y, Saavedra JM, Zhang L, Huang Z, Pang T.

Antioxid Redox Signal. 2018 Jan 10;28(2):141-163. doi: 10.1089/ars.2017.7003. Epub 2017 Aug 29.


Beneficial effects of Angiotensin II receptor blockers in brain disorders.

Saavedra JM.

Pharmacol Res. 2017 Nov;125(Pt A):91-103. doi: 10.1016/j.phrs.2017.06.017. Epub 2017 Jul 12. Review.


The nitric oxide donor JS-K sensitizes U87 glioma cells to repetitive irradiation.

Heckler M, Osterberg N, Guenzle J, Thiede-Stan NK, Reichardt W, Weidensteiner C, Saavedra JE, Weyerbrock A.

Tumour Biol. 2017 Jun;39(6):1010428317703922. doi: 10.1177/1010428317703922.


Association between Violent Crime and Psychosis in Men Serving Prison Terms.

Saavedra J, López M, Trigo ME.

Span J Psychol. 2017 Jun 27;20:E30. doi: 10.1017/sjp.2017.27.


Recovery and creative practices in people with severe mental illness: evaluating well-being and social inclusion.

Saavedra J, Pérez E, Crawford P, Arias S.

Disabil Rehabil. 2018 Apr;40(8):905-911. doi: 10.1080/09638288.2017.1278797. Epub 2017 Feb 6.


Physical activity in the classroom to prevent childhood obesity: a pilot study in Santiago, Chile.

Mardones F, Arnaiz P, Soto-Sánchez J, Saavedra J, Domínguez A, Rozowski J, Iriarte L, Cantwell Wood J.

J Nutr Sci. 2017 May 15;6:e21. doi: 10.1017/jns.2017.14. eCollection 2017.


JS-K, a nitric oxide prodrug, induces DNA damage and apoptosis in HBV-positive hepatocellular carcinoma HepG2.2.15 cell.

Liu Z, Li G, Gou Y, Xiao D, Luo G, Saavedra JE, Liu J, Wang H.

Biomed Pharmacother. 2017 Aug;92:989-997. doi: 10.1016/j.biopha.2017.05.141. Epub 2017 Jun 8.


Microglia: Housekeeper of the Central Nervous System.

Kabba JA, Xu Y, Christian H, Ruan W, Chenai K, Xiang Y, Zhang L, Saavedra JM, Pang T.

Cell Mol Neurobiol. 2018 Jan;38(1):53-71. doi: 10.1007/s10571-017-0504-2. Epub 2017 May 22. Review.


Reallocating sedentary time to moderate-to-vigorous physical activity but not to light-intensity physical activity is effective to reduce adiposity among youths: a systematic review and meta-analysis.

García-Hermoso A, Saavedra JM, Ramírez-Vélez R, Ekelund U, Del Pozo-Cruz B.

Obes Rev. 2017 Sep;18(9):1088-1095. doi: 10.1111/obr.12552. Epub 2017 May 19. Review.


Tracing the Enterococci from Paleozoic Origins to the Hospital.

Lebreton F, Manson AL, Saavedra JT, Straub TJ, Earl AM, Gilmore MS.

Cell. 2017 May 18;169(5):849-861.e13. doi: 10.1016/j.cell.2017.04.027. Epub 2017 May 11.


Mapping Transposon Insertions in Bacterial Genomes by Arbitrarily Primed PCR.

Saavedra JT, Schwartzman JA, Gilmore MS.

Curr Protoc Mol Biol. 2017 Apr 3;118:15.15.1-15.15.15. doi: 10.1002/cpmb.38.


ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFκB and STAT3 inhibition in glioblastoma.

Guenzle J, Wolf LJ, Garrelfs NW, Goeldner JM, Osterberg N, Schindler CR, Saavedra JE, Weyerbrock A.

Cell Death Discov. 2017 Feb 27;3:17006. doi: 10.1038/cddiscovery.2017.6. eCollection 2017.


Effects of JS-K, a novel anti-cancer nitric oxide prodrug, on gene expression in human hepatoma Hep3B cells.

Dong R, Wang X, Wang H, Liu Z, Liu J, Saavedra JE.

Biomed Pharmacother. 2017 Apr;88:367-373. doi: 10.1016/j.biopha.2017.01.080. Epub 2017 Jan 22.


Prevalence, geographic distribution and phenotypic differences of Piscirickettsia salmonis EM-90-like isolates.

Saavedra J, Hernandez N, Osses A, Castillo A, Cancino A, Grothusen H, Navas E, Henriquez P, Bohle H, Bustamante F, Bustos P, Mancilla M.

J Fish Dis. 2017 Aug;40(8):1055-1063. doi: 10.1111/jfd.12581. Epub 2017 Jan 11.


Preharvest Interval Periods and their relation to fruit growth stages and pesticide formulations.

Alister C, Araya M, Becerra K, Saavedra J, Kogan M.

Food Chem. 2017 Apr 15;221:548-554. doi: 10.1016/j.foodchem.2016.11.140. Epub 2016 Nov 28.


Validation of Thwaites Index for diagnosing tuberculous meningitis in a Colombian population.

Saavedra JS, Urrego S, Toro ME, Uribe CS, García J, Hernández O, Arango JC, Pérez ÁB, Franco A, Vélez IC, Del Corral H.

J Neurol Sci. 2016 Nov 15;370:112-118. doi: 10.1016/j.jns.2016.09.007. Epub 2016 Sep 9.


Design of a Digital-Based, Multicomponent Nutrition Guidance System for Prevention of Early Childhood Obesity.

Uesugi KH, Dattilo AM, Black MM, Saavedra JM.

J Obes. 2016;2016:5067421. doi: 10.1155/2016/5067421. Epub 2016 Aug 18.


Nitric oxide released from JS-K induces cell death by mitotic catastrophe as part of necrosis in glioblastoma multiforme.

Günzle J, Osterberg N, Saavedra JE, Weyerbrock A.

Cell Death Dis. 2016 Sep 1;7(9):e2349. doi: 10.1038/cddis.2016.254.


Skeletal involvement in Gaucher disease: An observational multicenter study of prognostic factors in the Argentine Gaucher disease patients.

Drelichman G, Fernández Escobar N, Basack N, Aversa L, Larroude MS, Aguilar G, Szlago M, Schenone A, Fynn A, Cuello MF, Aznar M, Fernández R, Ruiz A, Reichel P, Guelbert N, Robledo H, Watman N, Bolesina M, Elena G, Veber SE, Pujal G, Galván G, Chain JJ, Arizo A, Bietti J, Bar D, Dragosky M, Marquez M, Feldman L, Muller K, Zirone S, Buchovsky G, Lanza V, Sanabria A, Fernández I, Jaureguiberry R, Contte M, Barbieri María A, Maro A, Zárate G, Fernández G, Rapetti MC, Donato H, Degano A, Kantor G, Albina R, Á Lvarez Bollea M, Brun M, Bacciedoni V, Del Río F, Soberón B, Boido N, Schweri M, Borchichi S, Welsh V, Corrales M, Cedola A, Carvani A, Diez B, Richard L, Baduel C, Nuñez G, Colimodio R, Barazzutti L, Medici H, Meschengieser S, Damiani G, Nucifora M, Girardi B, Gómez S, Papucci M, Verón D, Quiroga L, Carro G, De Ambrosio P, Ferro J, Pujol M, Castella CC, Franco L, Nisnovich G, Veloso M, Pacheco I, Savarino M, Marino A, Saavedra JL.

Am J Hematol. 2016 Oct;91(10):E448-53. doi: 10.1002/ajh.24486. Epub 2016 Aug 22.


A Randomized Controlled Trial Assessing Growth of Infants Fed a 100% Whey Extensively Hydrolyzed Formula Compared With a Casein-Based Extensively Hydrolyzed Formula.

Fields D, Czerkies L, Sun S, Storm H, Saavedra J, Sorensen R.

Glob Pediatr Health. 2016 Apr 7;3:2333794X16636613. doi: 10.1177/2333794X16636613. eCollection 2016.


Does the menopausal status of female gynecologists affect their prescription of menopausal hormone therapy?

Vallejo MS, Witis S, Ojeda E, Mostajo D, Morera F, Meruvia N, Martino M, Lima S, Espinoza MT, Castillo O, Campostrini B, Danckers L, Blümel JE, Tserotas K, Sánchez H, Salinas C, Saavedra J, Rojas JA, Onatra W, Monterrosa A, Montaño A, Martínez J, González E, Gómez G, Calle A, Broutin G, Bencosme A, Arteaga E, Ayala F, Chedraui P.

Climacteric. 2016 Aug;19(4):387-92. doi: 10.1080/13697137.2016.1191460. Epub 2016 Jun 21.


Controlling activity and selectivity using water in the Au-catalysed preferential oxidation of CO in H2.

Saavedra J, Whittaker T, Chen Z, Pursell CJ, Rioux RM, Chandler BD.

Nat Chem. 2016 Jun;8(6):584-9. doi: 10.1038/nchem.2494. Epub 2016 Apr 18.


Force exerted by a nanoscale capillary water bridge between two planar substrates.

Valenzuela GE, Saavedra JH, Rozas RE, Toledo PG.

Phys Chem Chem Phys. 2016 Apr 28;18(16):11176-83. doi: 10.1039/c6cp00520a.


Personal and professional use of menopausal hormone therapy among gynecologists: A multinational study (REDLINC VII).

Danckers L, Blümel JE, Witis S, Vallejo MS, Tserotas K, Sánchez H, Salinas C, Saavedra J, Rojas JA, Onatra W, Ojeda E, Mostajo D, Morera F, Monterrosa A, Montaño A, Meruvia N, Martino M, Martínez J, Lima S, González E, Gómez G, Espinoza MT, Castillo O, Campostrini B, Calle A, Broutin G, Bencosme A, Arteaga E, Ayala F, Chedraui P.

Maturitas. 2016 May;87:67-71. doi: 10.1016/j.maturitas.2016.02.015. Epub 2016 Feb 28.


Evidence to Consider Angiotensin II Receptor Blockers for the Treatment of Early Alzheimer's Disease.

Saavedra JM.

Cell Mol Neurobiol. 2016 Mar;36(2):259-79. doi: 10.1007/s10571-015-0327-y. Epub 2016 Mar 18. Review.


Is high-intensity interval training more effective on improving cardiometabolic risk and aerobic capacity than other forms of exercise in overweight and obese youth? A meta-analysis.

García-Hermoso A, Cerrillo-Urbina AJ, Herrera-Valenzuela T, Cristi-Montero C, Saavedra JM, Martínez-Vizcaíno V.

Obes Rev. 2016 Jun;17(6):531-40. doi: 10.1111/obr.12395. Epub 2016 Mar 7. Review.


Assessment of Growth of Infants Fed an Amino Acid-Based Formula.

Corkins M, Czerkies LA, Storm HM, Sun S, Saavedra JM.

Clin Med Insights Pediatr. 2016 Feb 4;10:3-9. doi: 10.4137/CMPed.S33071. eCollection 2016.


An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimer's disease.

Elkahloun AG, Hafko R, Saavedra JM.

Alzheimers Res Ther. 2016 Jan 28;8:5. doi: 10.1186/s13195-015-0167-5.


[Perceptions on healthcare in people with self-identified mental health problems in the rural areas of Peru].

Saavedra JE, Uchofen-Herrera V.

Rev Peru Med Exp Salud Publica. 2016 Oct-Dec;33(4):785-793. doi: 10.17843/rpmesp.2016.334.2566. Spanish.


Correction: New Archaeological Evidence for an Early Human Presence at Monte Verde, Chile.

Dillehay TD, Ocampo C, Saavedra J, Sawakuchi AO, Vega RM, Pino M, Collins MB, Cummings LS, Arregui I, Villagran XS, Hartmann GA, Mella M, González A, Dix G.

PLoS One. 2015 Dec 23;10(12):e0145471. doi: 10.1371/journal.pone.0145471. eCollection 2015. No abstract available.


Exercise-based interventions and C-reactive protein in overweight and obese youths: a meta-analysis of randomized controlled trials.

García-Hermoso A, Sánchez-López M, Escalante Y, Saavedra JM, Martínez-Vizcaíno V.

Pediatr Res. 2016 Apr;79(4):522-7. doi: 10.1038/pr.2015.274. Epub 2015 Dec 21. Review.


Disentangling Disadvantage: Can We Distinguish Good Teaching from Classroom Composition?

Zamarro G, Engberg J, Saavedra JE, Steele J.

J Res Educ Eff. 2015;8(1):84-111. Epub 2015 Jan 12.

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