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Items: 12


Use of anti-CRISPR protein AcrIIA4 as a capture ligand for CRISPR/Cas9 detection.

Johnston RK, Seamon KJ, Saada EA, Podlevsky JD, Branda SS, Timlin JA, Harper JC.

Biosens Bioelectron. 2019 Sep 15;141:111361. doi: 10.1016/j.bios.2019.111361. Epub 2019 May 31.


Versatile High-Throughput Fluorescence Assay for Monitoring Cas9 Activity.

Seamon KJ, Light YK, Saada EA, Schoeniger JS, Harmon B.

Anal Chem. 2018 Jun 5;90(11):6913-6921. doi: 10.1021/acs.analchem.8b01155. Epub 2018 May 24.


Timescale Separation of Positive and Negative Signaling Creates History-Dependent Responses to IgE Receptor Stimulation.

Harmon B, Chylek LA, Liu Y, Mitra ED, Mahajan A, Saada EA, Schudel BR, Holowka DA, Baird BA, Wilson BS, Hlavacek WS, Singh AK.

Sci Rep. 2017 Nov 14;7(1):15586. doi: 10.1038/s41598-017-15568-2.


Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei.

Langousis G, Shimogawa MM, Saada EA, Vashisht AA, Spreafico R, Nager AR, Barshop WD, Nachury MV, Wohlschlegel JA, Hill KL.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):632-7. doi: 10.1073/pnas.1518079113. Epub 2015 Dec 31.


"With a Little Help from My Friends"-Social Motility in Trypanosoma brucei.

Saada EA, DeMarco SF, Shimogawa MM, Hill KL.

PLoS Pathog. 2015 Dec 17;11(12):e1005272. doi: 10.1371/journal.ppat.1005272. eCollection 2015 Dec. Review. No abstract available.


Cell Surface Proteomics Provides Insight into Stage-Specific Remodeling of the Host-Parasite Interface in Trypanosoma brucei.

Shimogawa MM, Saada EA, Vashisht AA, Barshop WD, Wohlschlegel JA, Hill KL.

Mol Cell Proteomics. 2015 Jul;14(7):1977-88. doi: 10.1074/mcp.M114.045146. Epub 2015 May 11.


Cyclic AMP Regulates Social Behavior in African Trypanosomes.

Oberholzer M, Saada EA, Hill KL.

MBio. 2015 Apr 28;6(3):e01954-14. doi: 10.1128/mBio.01954-14.


Insect stage-specific adenylate cyclases regulate social motility in African trypanosomes.

Lopez MA, Saada EA, Hill KL.

Eukaryot Cell. 2015 Jan;14(1):104-12. doi: 10.1128/EC.00217-14. Epub 2014 Nov 21.


eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation in Trypanosoma brucei.

Freire ER, Vashisht AA, Malvezzi AM, Zuberek J, Langousis G, Saada EA, Nascimento Jde F, Stepinski J, Darzynkiewicz E, Hill K, De Melo Neto OP, Wohlschlegel JA, Sturm NR, Campbell DA.

RNA. 2014 Aug;20(8):1272-86. doi: 10.1261/rna.045534.114. Epub 2014 Jun 24.


Insect stage-specific receptor adenylate cyclases are localized to distinct subdomains of the Trypanosoma brucei Flagellar membrane.

Saada EA, Kabututu ZP, Lopez M, Shimogawa MM, Langousis G, Oberholzer M, Riestra A, Jonsson ZO, Wohlschlegel JA, Hill KL.

Eukaryot Cell. 2014 Aug;13(8):1064-76. doi: 10.1128/EC.00019-14. Epub 2014 May 30.


Trypanosoma brucei translation initiation factor homolog EIF4E6 forms a tripartite cytosolic complex with EIF4G5 and a capping enzyme homolog.

Freire ER, Malvezzi AM, Vashisht AA, Zuberek J, Saada EA, Langousis G, Nascimento JD, Moura D, Darzynkiewicz E, Hill K, de Melo Neto OP, Wohlschlegel JA, Sturm NR, Campbell DA.

Eukaryot Cell. 2014 Jul;13(7):896-908. doi: 10.1128/EC.00071-14. Epub 2014 May 16.


Independent analysis of the flagellum surface and matrix proteomes provides insight into flagellum signaling in mammalian-infectious Trypanosoma brucei.

Oberholzer M, Langousis G, Nguyen HT, Saada EA, Shimogawa MM, Jonsson ZO, Nguyen SM, Wohlschlegel JA, Hill KL.

Mol Cell Proteomics. 2011 Oct;10(10):M111.010538. doi: 10.1074/mcp.M111.010538. Epub 2011 Jun 19.

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