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Items: 1 to 50 of 184

1.

Degradation of Proteins and Starch by Combined Immobilization of Protease, α-Amylase and β-Galactosidase on a Single Electrospun Nanofibrous Membrane.

Cloete WJ, Hayward S, Swart P, Klumperman B.

Molecules. 2019 Jan 31;24(3). pii: E508. doi: 10.3390/molecules24030508.

2.

Immediate Use of Continuous Positive Airway Pressure in Patients With Obstructive Sleep Apnea Following Transsphenoidal Pituitary Surgery: A Case Series.

Rieley W, Askari A, Akagami R, Gooderham PA, Swart PA, Flexman AM.

J Neurosurg Anesthesiol. 2019 Jan 8. doi: 10.1097/ANA.0000000000000573. [Epub ahead of print]

PMID:
30628938
3.

Guidelines to the Practice of Anesthesia - Revised Edition 2019.

Dobson G, Chow L, Flexman A, Hurdle H, Kurrek M, Laflamme C, Perrault MA, Sparrow K, Stacey S, Swart P, Wong M.

Can J Anaesth. 2019 Jan;66(1):75-108. doi: 10.1007/s12630-018-1248-2. Epub 2018 Dec 17.

PMID:
30560409
4.

Procedural sedation: a position paper of the Canadian Anesthesiologists' Society.

Dobson G, Chong MA, Chow L, Flexman A, Hurdle H, Kurrek M, Laflamme C, Perrault MA, Sparrow K, Stacey S, Swart PA, Wong M.

Can J Anaesth. 2018 Dec;65(12):1372-1384. doi: 10.1007/s12630-018-1230-z. Epub 2018 Sep 27. No abstract available.

PMID:
30264187
5.

Early-Ethanol Exposure Induced Region-Specific Changes in Metabolic Proteins in the Rat Brain: A Proteomics Study.

Swart PC, Russell VA, Vlok NM, Dimatelis JJ.

J Mol Neurosci. 2018 Jul;65(3):277-288. doi: 10.1007/s12031-018-1097-z. Epub 2018 Jun 18.

PMID:
29915983
6.

Maternal separation stress reduced prenatal-ethanol-induced increase in exploratory behaviour and extracellular signal-regulated kinase activity.

Swart PC, Russell VA, Dimatelis JJ.

Behav Brain Res. 2019 Jan 1;356:470-482. doi: 10.1016/j.bbr.2018.06.004. Epub 2018 Jun 13.

PMID:
29908221
7.

Estrogenic activity, selected plasticizers and potential health risks associated with bottled water in South Africa.

Aneck-Hahn NH, Van Zijl MC, Swart P, Truebody B, Genthe B, Charmier J, Jager C.

J Water Health. 2018 Apr;16(2):253-262. doi: 10.2166/wh.2018.043.

PMID:
29676761
8.

A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the "Metabolites in Safety Testing" Regulatory Guidance.

Schadt S, Bister B, Chowdhury SK, Funk C, Hop CECA, Humphreys WG, Igarashi F, James AD, Kagan M, Khojasteh SC, Nedderman ANR, Prakash C, Runge F, Scheible H, Spracklin DK, Swart P, Tse S, Yuan J, Obach RS.

Drug Metab Dispos. 2018 Jun;46(6):865-878. doi: 10.1124/dmd.117.079848. Epub 2018 Feb 27. Review.

PMID:
29487142
9.

Estrogenic activity, chemical levels and health risk assessment of municipal distribution point water from Pretoria and Cape Town, South Africa.

Van Zijl MC, Aneck-Hahn NH, Swart P, Hayward S, Genthe B, De Jager C.

Chemosphere. 2017 Nov;186:305-313. doi: 10.1016/j.chemosphere.2017.07.130. Epub 2017 Jul 26.

PMID:
28787686
10.

Prehistoric cooking versus accurate palaeotemperature records in shell midden constituents.

Müller P, Staudigel PT, Murray ST, Vernet R, Barusseau JP, Westphal H, Swart PK.

Sci Rep. 2017 Jun 15;7(1):3555. doi: 10.1038/s41598-017-03715-8.

11.

Sutherlandia frutescens modulates adrenal hormone biosynthesis, acts as a selective glucocorticoid receptor agonist (SEGRA) and displays anti-mineralocorticoid properties.

Sergeant CA, Africander D, Swart P, Swart AC.

J Ethnopharmacol. 2017 Apr 18;202:290-301. doi: 10.1016/j.jep.2017.03.019. Epub 2017 Mar 18.

PMID:
28323049
12.

A quantitative comparison of micro-CT preparations in Dipteran flies.

Swart P, Wicklein M, Sykes D, Ahmed F, Krapp HG.

Sci Rep. 2016 Dec 21;6:39380. doi: 10.1038/srep39380.

13.

In Vitro Chemopreventive Properties of Green Tea, Rooibos and Honeybush Extracts in Skin Cells.

Magcwebeba TU, Swart P, Swanevelder S, Joubert E, Gelderblom WC.

Molecules. 2016 Nov 25;21(12). pii: E1622.

14.

The potential role of polyphenols in the modulation of skin cell viability by Aspalathus linearis and Cyclopia spp. herbal tea extracts in vitro.

Magcwebeba TU, Riedel S, Swanevelder S, Swart P, De Beer D, Joubert E, Andreas Gelderblom WC.

J Pharm Pharmacol. 2016 Nov;68(11):1440-1453. doi: 10.1111/jphp.12629. Epub 2016 Sep 27.

PMID:
27671741
15.
16.

The metabolic fate and receptor interaction of 16α-hydroxyprogesterone and its 5α-reduced metabolite, 16α-hydroxy-dihydroprogesterone.

van Rooyen D, du Toit T, Louw-du Toit R, Africander D, Swart P, Swart AC.

Mol Cell Endocrinol. 2017 Feb 5;441:86-98. doi: 10.1016/j.mce.2016.09.025. Epub 2016 Sep 21.

PMID:
27664517
17.

Early ethanol exposure and vinpocetine treatment alter learning- and memory-related proteins in the rat hippocampus and prefrontal cortex.

Swart PC, Currin CB, Russell VA, Dimatelis JJ.

J Neurosci Res. 2017 May;95(5):1204-1215. doi: 10.1002/jnr.23894. Epub 2016 Sep 10.

PMID:
27614144
18.

Species-specific responses to climate change and community composition determine future calcification rates of Florida Keys reefs.

Okazaki RR, Towle EK, van Hooidonk R, Mor C, Winter RN, Piggot AM, Cunning R, Baker AC, Klaus JS, Swart PK, Langdon C.

Glob Chang Biol. 2017 Mar;23(3):1023-1035. doi: 10.1111/gcb.13481. Epub 2016 Sep 23.

PMID:
27561209
19.

Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black South African family.

Carstens N, Williams S, Goolam S, Carmichael T, Cheung MS, Büchmann-Møller S, Sultan M, Staedtler F, Zou C, Swart P, Rice DS, Lacoste A, Paes K, Ramsay M.

BMC Med Genet. 2016 Jul 20;17(1):47. doi: 10.1186/s12881-016-0308-0.

20.

The abrupt onset of the modern South Asian Monsoon winds.

Betzler C, Eberli GP, Kroon D, Wright JD, Swart PK, Nath BN, Alvarez-Zarikian CA, Alonso-García M, Bialik OM, Blättler CL, Guo JA, Haffen S, Horozal S, Inoue M, Jovane L, Lanci L, Laya JC, Mee AL, Lüdmann T, Nakakuni M, Niino K, Petruny LM, Pratiwi SD, Reijmer JJ, Reolid J, Slagle AL, Sloss CR, Su X, Yao Z, Young JR.

Sci Rep. 2016 Jul 20;6:29838. doi: 10.1038/srep29838.

21.

Graph-based linear scaling electronic structure theory.

Niklasson AM, Mniszewski SM, Negre CF, Cawkwell MJ, Swart PJ, Mohd-Yusof J, Germann TC, Wall ME, Bock N, Rubensson EH, Djidjev H.

J Chem Phys. 2016 Jun 21;144(23):234101. doi: 10.1063/1.4952650.

PMID:
27334148
22.

The impact of early human data on clinical development: there is time to win.

Swart P, Lozac'h F, Simon M, van Duijn E, Vaes WH.

Drug Discov Today. 2016 Jun;21(6):873-9. doi: 10.1016/j.drudis.2016.03.012. Epub 2016 Mar 29.

PMID:
27046542
23.

ADME studies of [5-(3)H]-2'-O-methyluridine nucleoside in mice: a building block in siRNA therapeutics.

Lozac'h F, Christensen J, Faller T, van de Kerkhof E, Krauser J, Garnier M, Litherland K, Catoire A, Natt F, Hunziker J, Swart P.

Pharmacol Res Perspect. 2016 Feb 1;4(1):e00209. doi: 10.1002/prp2.209. eCollection 2016 Feb.

24.

Discovery of Compound A--a selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activity.

Lesovaya E, Yemelyanov A, Swart AC, Swart P, Haegeman G, Budunova I.

Oncotarget. 2015 Oct 13;6(31):30730-44. doi: 10.18632/oncotarget.5078. Review.

25.

The inversion of aragonite to calcite during the sampling of skeletal archives: implications for proxy interpretation.

Waite AJ, Swart PK.

Rapid Commun Mass Spectrom. 2015 May 30;29(10):955-64. doi: 10.1002/rcm.7180.

PMID:
26407310
26.

Absorption, distribution, metabolism, and excretion of [(14)C]BYL719 (alpelisib) in healthy male volunteers.

James A, Blumenstein L, Glaenzel U, Jin Y, Demailly A, Jakab A, Hansen R, Hazell K, Mehta A, Trandafir L, Swart P.

Cancer Chemother Pharmacol. 2015 Oct;76(4):751-60. doi: 10.1007/s00280-015-2842-4. Epub 2015 Aug 8.

PMID:
26254025
27.

Advances in the analytical methodologies: Profiling steroids in familiar pathways-challenging dogmas.

Bloem LM, Storbeck KH, Swart P, du Toit T, Schloms L, Swart AC.

J Steroid Biochem Mol Biol. 2015 Sep;153:80-92. doi: 10.1016/j.jsbmb.2015.04.009. Epub 2015 Apr 11. Review.

PMID:
25869556
28.

Evaluation of the ScopeControl endoscope test system in six hospitals in The Netherlands.

Noordmans HJ, de Braak M, Wientjes R, Martens E, Lindenhovius K, Swart P.

Phys Med. 2015 Mar;31(2):152-8. doi: 10.1016/j.ejmp.2014.12.006. Epub 2015 Jan 15.

PMID:
25599625
29.

Relative contribution of P450c17 towards the acute cortisol response: Lessons from sheep and goats.

Hough D, Storbeck K, Cloete SW, Swart AC, Swart P.

Mol Cell Endocrinol. 2015 Jun 15;408:107-13. doi: 10.1016/j.mce.2015.01.018. Epub 2015 Jan 15. Review.

PMID:
25597634
30.

Cytochrome b5 modulates multiple reactions in steroidogenesis by diverse mechanisms.

Storbeck KH, Swart AC, Fox CL, Swart P.

J Steroid Biochem Mol Biol. 2015 Jul;151:66-73. doi: 10.1016/j.jsbmb.2014.11.024. Epub 2014 Nov 23. Review.

PMID:
25446886
31.

Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation.

Manevski N, Swart P, Balavenkatraman KK, Bertschi B, Camenisch G, Kretz O, Schiller H, Walles M, Ling B, Wettstein R, Schaefer DJ, Itin P, Ashton-Chess J, Pognan F, Wolf A, Litherland K.

Drug Metab Dispos. 2015 Jan;43(1):126-39. doi: 10.1124/dmd.114.060350. Epub 2014 Oct 22.

PMID:
25339109
32.

Aldehyde oxidase activity in fresh human skin.

Manevski N, Balavenkatraman KK, Bertschi B, Swart P, Walles M, Camenisch G, Schiller H, Kretz O, Ling B, Wettstein R, Schaefer DJ, Pognan F, Wolf A, Litherland K.

Drug Metab Dispos. 2014 Dec;42(12):2049-57. doi: 10.1124/dmd.114.060368. Epub 2014 Sep 23.

PMID:
25249692
33.

Phenotypic and metabolic investigation of a CSF-1R kinase receptor inhibitor (BLZ945) and its pharmacologically active metabolite.

Krauser JA, Jin Y, Walles M, Pfaar U, Sutton J, Wiesmann M, Graf D, Pflimlin-Fritschy V, Wolf T, Camenisch G, Swart P.

Xenobiotica. 2015 Feb;45(2):107-23. doi: 10.3109/00498254.2014.945988. Epub 2014 Sep 2.

PMID:
25180976
34.

Interpreting carbonate and organic carbon isotope covariance in the sedimentary record.

Oehlert AM, Swart PK.

Nat Commun. 2014 Aug 19;5:4672. doi: 10.1038/ncomms5672.

PMID:
25135457
35.

Iron uptake and ferrokinetics in healthy male subjects of an iron-based oral phosphate binder (SBR759) labeled with the stable isotope (58)Fe.

Gschwind HP, Schmid DG, von Blanckenburg F, Oelze M, van Zuilen K, Slade AJ, Stitah S, Kaufmann D, Swart P.

Metallomics. 2014 Nov;6(11):2062-71. doi: 10.1039/c4mt00126e.

PMID:
25017110
36.

An iron stable isotope comparison between human erythrocytes and plasma.

von Blanckenburg F, Oelze M, Schmid DG, van Zuilen K, Gschwind HP, Slade AJ, Stitah S, Kaufmann D, Swart P.

Metallomics. 2014 Nov;6(11):2052-61. doi: 10.1039/c4mt00124a.

PMID:
25017012
37.

Part 2: ultrastructural changes of fibrin networks during three phases of pregnancy: a qualitative investigation.

Swanepoel AC, Lindeque BG, Swart PJ, Abdool Z, Pretorius E.

Microsc Res Tech. 2014 Aug;77(8):602-8. doi: 10.1002/jemt.22385. Epub 2014 May 24.

PMID:
24861478
38.

Estrogen causes ultrastructural changes of fibrin networks during the menstrual cycle: a qualitative investigation.

Swanepoel AC, Lindeque BG, Swart PJ, Abdool Z, Pretorius E.

Microsc Res Tech. 2014 Aug;77(8):594-601. doi: 10.1002/jemt.22378. Epub 2014 May 20.

PMID:
24841871
39.

Absorption, distribution, metabolism, and excretion (ADME) of ¹⁴C-sonidegib (LDE225) in healthy volunteers.

Zollinger M, Lozac'h F, Hurh E, Emotte C, Bauly H, Swart P.

Cancer Chemother Pharmacol. 2014 Jul;74(1):63-75. doi: 10.1007/s00280-014-2468-y. Epub 2014 May 10.

PMID:
24817600
40.

Measurement of δ18O and δ2H values of fluid inclusion water in speleothems using cavity ring-down spectroscopy compared with isotope ratio mass spectrometry.

Arienzo MM, Swart PK, Vonhof HB.

Rapid Commun Mass Spectrom. 2013 Dec 15;27(23):2616-24. doi: 10.1002/rcm.6723.

PMID:
24591022
41.

Biodistribution and metabolism studies of lipid nanoparticle-formulated internally [3H]-labeled siRNA in mice.

Christensen J, Litherland K, Faller T, van de Kerkhof E, Natt F, Hunziker J, Boos J, Beuvink I, Bowman K, Baryza J, Beverly M, Vargeese C, Heudi O, Stoeckli M, Krauser J, Swart P.

Drug Metab Dispos. 2014 Mar;42(3):431-40. doi: 10.1124/dmd.113.055434. Epub 2014 Jan 3.

PMID:
24389421
42.

Modeling fossil energy demands of primary nonferrous metal production: the case of copper.

Swart P, Dewulf J.

Environ Sci Technol. 2013 Dec 17;47(24):13917-24. doi: 10.1021/es4030518. Epub 2013 Nov 22.

PMID:
24266773
43.

Rooibos influences glucocorticoid levels and steroid ratios in vivo and in vitro: a natural approach in the management of stress and metabolic disorders?

Schloms L, Smith C, Storbeck KH, Marnewick JL, Swart P, Swart AC.

Mol Nutr Food Res. 2014 Mar;58(3):537-49. doi: 10.1002/mnfr.201300463. Epub 2013 Sep 11.

PMID:
24022885
44.

Mixed matrix hollow fiber membranes for removal of protein-bound toxins from human plasma.

Tijink MS, Wester M, Glorieux G, Gerritsen KG, Sun J, Swart PC, Borneman Z, Wessling M, Vanholder R, Joles JA, Stamatialis D.

Biomaterials. 2013 Oct;34(32):7819-28. doi: 10.1016/j.biomaterials.2013.07.008. Epub 2013 Jul 19.

PMID:
23876759
45.

11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: a putative role in castration resistant prostate cancer?

Storbeck KH, Bloem LM, Africander D, Schloms L, Swart P, Swart AC.

Mol Cell Endocrinol. 2013 Sep 5;377(1-2):135-46. doi: 10.1016/j.mce.2013.07.006. Epub 2013 Jul 13.

PMID:
23856005
46.

Metabolism and disposition of the metabotropic glutamate receptor 5 antagonist (mGluR5) mavoglurant (AFQ056) in healthy subjects.

Walles M, Wolf T, Jin Y, Ritzau M, Leuthold LA, Krauser J, Gschwind HP, Carcache D, Kittelmann M, Ocwieja M, Ufer M, Woessner R, Chakraborty A, Swart P.

Drug Metab Dispos. 2013 Sep;41(9):1626-41. doi: 10.1124/dmd.112.050716. Epub 2013 Jun 17.

PMID:
23775850
47.

Whole-body scanning PCR; a highly sensitive method to study the biodistribution of mRNAs, noncoding RNAs and therapeutic oligonucleotides.

Boos JA, Kirk DW, Piccolotto ML, Zuercher W, Gfeller S, Neuner P, Dattler A, Wishart WL, Von Arx F, Beverly M, Christensen J, Litherland K, van de Kerkhof E, Swart PJ, Faller T, Beyerbach A, Morrissey D, Hunziker J, Beuvink I.

Nucleic Acids Res. 2013 Aug;41(15):e145. doi: 10.1093/nar/gkt515. Epub 2013 Jun 13.

48.

Efficacy of emodepside plus toltrazuril oral suspension for dogs (Procox®, Bayer) against Trichuris vulpis in naturally infected dogs.

Petry G, Altreuther G, Wolken S, Swart P, Kok DJ.

Parasitol Res. 2013 Aug;112 Suppl 1:133-8. doi: 10.1007/s00436-013-3287-5.

PMID:
23756961
49.

11β-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione.

Swart AC, Schloms L, Storbeck KH, Bloem LM, Toit Td, Quanson JL, Rainey WE, Swart P.

J Steroid Biochem Mol Biol. 2013 Nov;138:132-42. doi: 10.1016/j.jsbmb.2013.04.010. Epub 2013 May 16.

PMID:
23685396
50.

Metabolism studies of unformulated internally [3H]-labeled short interfering RNAs in mice.

Christensen J, Litherland K, Faller T, van de Kerkhof E, Natt F, Hunziker J, Krauser J, Swart P.

Drug Metab Dispos. 2013 Jun;41(6):1211-9. doi: 10.1124/dmd.112.050666. Epub 2013 Mar 22.

PMID:
23524663

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