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Items: 42

1.

Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria.

Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B.

Sci Rep. 2016 Nov 25;6:37798. doi: 10.1038/srep37798.

2.

Amphiphysin I phosphorylation on residue threonine 260 in a pentylenetetrazole-induced seizure model.

Choudhury M, Kleiner O, Chung R, Barden L, Morgan L, Patel TR, Staddon JM.

Neurosci Lett. 2008 Oct 31;444(3):245-9. doi: 10.1016/j.neulet.2008.08.055. Epub 2008 Aug 23.

PMID:
18761055
3.

Inflammation and dephosphorylation of the tight junction protein occludin in an experimental model of multiple sclerosis.

Morgan L, Shah B, Rivers LE, Barden L, Groom AJ, Chung R, Higazi D, Desmond H, Smith T, Staddon JM.

Neuroscience. 2007 Jul 13;147(3):664-73. Epub 2007 Jun 7.

PMID:
17560040
4.

Development of a pentylenetetrazole-induced seizure model to evaluate kinase inhibitor efficacy in the central nervous system.

Morgan L, Neame SJ, Child H, Chung R, Shah B, Barden L, Staddon JM, Patel TR.

Neurosci Lett. 2006 Mar 6;395(2):143-8. Epub 2005 Nov 21.

PMID:
16300886
5.

The neuroprotective action of JNK3 inhibitors based on the 6,7-dihydro-5H-pyrrolo[1,2-a]imidazole scaffold.

Graczyk PP, Khan A, Bhatia GS, Palmer V, Medland D, Numata H, Oinuma H, Catchick J, Dunne A, Ellis M, Smales C, Whitfield J, Neame SJ, Shah B, Wilton D, Morgan L, Patel T, Chung R, Desmond H, Staddon JM, Sato N, Inoue A.

Bioorg Med Chem Lett. 2005 Nov 1;15(21):4666-70.

PMID:
16153829
6.

Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase.

Kuo JC, Lin JR, Staddon JM, Hosoya H, Chen RH.

J Cell Sci. 2003 Dec 1;116(Pt 23):4777-90.

7.

High-throughput methods to detect dimerization of Bcl-2 family proteins.

Whitfield J, Harada K, Bardelle C, Staddon JM.

Anal Biochem. 2003 Nov 15;322(2):170-8.

PMID:
14596824
8.
9.

Occludin phosphorylation: identification of an occludin kinase in brain and cell extracts as CK2.

Smales C, Ellis M, Baumber R, Hussain N, Desmond H, Staddon JM.

FEBS Lett. 2003 Jun 19;545(2-3):161-6.

10.

Heme oxygenase modulates oxidant-signaled airway smooth muscle contractility: role of bilirubin.

Samb A, Taillé C, Almolki A, Mégret J, Staddon JM, Aubier M, Boczkowski J.

Am J Physiol Lung Cell Mol Physiol. 2002 Sep;283(3):L596-603.

11.

Regulation of tight junction permeability and occludin phosphorylation by Rhoa-p160ROCK-dependent and -independent mechanisms.

Hirase T, Kawashima S, Wong EY, Ueyama T, Rikitake Y, Tsukita S, Yokoyama M, Staddon JM.

J Biol Chem. 2001 Mar 30;276(13):10423-31. Epub 2001 Jan 3.

12.
13.

Vascular endothelial growth factor stimulates dephosphorylation of the catenins p120 and p100 in endothelial cells.

Wong EY, Morgan L, Smales C, Lang P, Gubby SE, Staddon JM.

Biochem J. 2000 Feb 15;346 Pt 1:209-16.

14.

Phosphodiesterase 4 conformers: preparation of recombinant enzymes and assay for inhibitors.

Bardelle C, Smales C, Ito M, Nomoto K, Wong EY, Kato H, Saeki T, Staddon JM.

Anal Biochem. 1999 Nov 15;275(2):148-55.

PMID:
10552898
15.

Treatment with BBB022A or rolipram stabilizes the blood-brain barrier in experimental autoimmune encephalomyelitis: an additional mechanism for the therapeutic effect of type IV phosphodiesterase inhibitors.

Folcik VA, Smith T, O'Bryant S, Kawczak JA, Zhu B, Sakurai H, Kajiwara A, Staddon JM, Glabinski A, Chernosky AL, Tani M, Johnson JM, Tuohy VK, Rubin LL, Ransohoff RM.

J Neuroimmunol. 1999 Jun 1;97(1-2):119-28.

PMID:
10408965
16.

The cell biology of the blood-brain barrier.

Rubin LL, Staddon JM.

Annu Rev Neurosci. 1999;22:11-28. Review.

PMID:
10202530
17.
18.
19.

Occludin as a possible determinant of tight junction permeability in endothelial cells.

Hirase T, Staddon JM, Saitou M, Ando-Akatsuka Y, Itoh M, Furuse M, Fujimoto K, Tsukita S, Rubin LL.

J Cell Sci. 1997 Jul;110 ( Pt 14):1603-13.

20.

Lysophosphatidic acid increases tight junction permeability in cultured brain endothelial cells.

Schulze C, Smales C, Rubin LL, Staddon JM.

J Neurochem. 1997 Mar;68(3):991-1000.

21.

Cell adhesion, cell junctions and the blood-brain barrier.

Staddon JM, Rubin LL.

Curr Opin Neurobiol. 1996 Oct;6(5):622-7. Review.

PMID:
8937826
22.

Signal transduction at the blood-brain barrier.

Staddon JM, Herrenknecht K, Schulze C, Smales C, Rubin LL.

Biochem Soc Trans. 1995 Aug;23(3):475-9. Review. No abstract available.

PMID:
8566371
23.

p120, a p120-related protein (p100), and the cadherin/catenin complex.

Staddon JM, Smales C, Schulze C, Esch FS, Rubin LL.

J Cell Biol. 1995 Jul;130(2):369-81.

24.

Evidence that tyrosine phosphorylation may increase tight junction permeability.

Staddon JM, Herrenknecht K, Smales C, Rubin LL.

J Cell Sci. 1995 Feb;108 ( Pt 2):609-19.

25.
26.

Pasteurella multocida toxin is a potent inducer of anchorage-independent cell growth.

Higgins TE, Murphy AC, Staddon JM, Lax AJ, Rozengurt E.

Proc Natl Acad Sci U S A. 1992 May 15;89(10):4240-4.

28.

Pasteurella multocida toxin, a potent mitogen, increases inositol 1,4,5-trisphosphate and mobilizes Ca2+ in Swiss 3T3 cells.

Staddon JM, Barker CJ, Murphy AC, Chanter N, Lax AJ, Michell RH, Rozengurt E.

J Biol Chem. 1991 Mar 15;266(8):4840-7.

29.

Sequence analysis of the potent mitogenic toxin of Pasteurella multocida.

Lax AJ, Chanter N, Pullinger GD, Higgins T, Staddon JM, Rozengurt E.

FEBS Lett. 1990 Dec 17;277(1-2):59-64.

30.

Effects of age and adenosine in the modulation of insulin action on rat adipocyte metabolism.

Rolband GC, Furth ED, Staddon JM, Rogus EM, Goldberg AP.

J Gerontol. 1990 Sep;45(5):B174-8.

PMID:
2203845
31.
32.

Pasteurella multocida toxin: potent mitogen for cultured fibroblasts.

Rozengurt E, Higgins T, Chanter N, Lax AJ, Staddon JM.

Proc Natl Acad Sci U S A. 1990 Jan;87(1):123-7.

33.

Decrease with senescence in the norepinephrine-induced phosphorylation of myofilament proteins in isolated rat cardiac myocytes.

Sakai M, Danziger RS, Staddon JM, Lakatta EG, Hansford RG.

J Mol Cell Cardiol. 1989 Dec;21(12):1327-36.

PMID:
2561160
37.

The relationship between the cytosolic free calcium ion concentration and the control of pyruvate dehydrogenase.

Hansford RG, Staddon JM.

Soc Gen Physiol Ser. 1987;42:241-57. No abstract available.

PMID:
3505362
40.
41.

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