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Items: 14

1.

Laparoscopic management of recurrent pheochromocytoma: A case report.

Garg H, Uppal M, Sreedharan SK, Aggarwal S.

J Minim Access Surg. 2016 Jul-Sep;12(3):278-80. doi: 10.4103/0972-9941.181290.

2.

Isomerization of the uncomplexed actinidin molecule: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation.

Reid JD, Hussain S, Bailey TS, Sonkaria S, Sreedharan SK, Thomas EW, Resmini M, Brocklehurst K.

Biochem J. 2004 Mar 1;378(Pt 2):699-703.

3.

Variation in aspects of cysteine proteinase catalytic mechanism deduced by spectroscopic observation of dithioester intermediates, kinetic analysis and molecular dynamics simulations.

Reid JD, Hussain S, Sreedharan SK, Bailey TS, Pinitglang S, Thomas EW, Verma CS, Brocklehurst K.

Biochem J. 2001 Jul 15;357(Pt 2):343-52.

4.

A classical enzyme active center motif lacks catalytic competence until modulated electrostatically.

Pinitglang S, Watts AB, Patel M, Reid JD, Noble MA, Gul S, Bokth A, Naeem A, Patel H, Thomas EW, Sreedharan SK, Verma C, Brocklehurst K.

Biochemistry. 1997 Aug 19;36(33):9968-82.

PMID:
9254592
5.

Design and synthesis of substrate-derived n-acylaminoalkyl 2-pyridyl disulphides as probes of cysteine proteinase mechanism.

Brocklehurst K, Thomas EW, Verma C, Patel M, Sreedharan SK.

Biochem Soc Trans. 1997 Feb;25(1):92S. No abstract available.

PMID:
9056990
6.

Effects of the quality of the P2-S2 hydrophobic contacts on the catalytic activities of papain, caricain and ficin and their generation by electrostatic switches.

Pinitglang S, Patel M, Noble M, Sreedharan SK, Verma C, Thomas EW, Brocklehurst K.

Biochem Soc Trans. 1997 Feb;25(1):88S. No abstract available.

PMID:
9056986
7.

Are polyclonal catalytic antibodies heterogeneous?

Carter S, Resmini M, Simms C, Sreedharan SK, Gallacher G, Brocklehurst K.

Biochem Soc Trans. 1997 Feb;25(1):86S. No abstract available.

PMID:
9056984
8.

Is the dust mite allergen Der p1 a cysteine proteinase?

Chambers L, Sreedharan SK, Deam S, Kalsheker N, Brocklehurst K.

Biochem Soc Trans. 1997 Feb;25(1):85S. No abstract available.

PMID:
9056983
10.

Expression cloning of a dust mite cysteine proteinase, Der p1, a major allergen associated with asthma and hypersensitivity reactions.

Scobie G, Ravindran V, Deam SM, Thomas M, Sreedharan SK, Brocklehurst K, Kalsheker N.

Biochem Soc Trans. 1994 Nov;22(4):448S. No abstract available.

PMID:
7698465
11.

trans-epoxysuccinyl-L-leucylamido (4-guanidino)-butane (E-64) inhibits trypsin-catalysed hydrolysis possibly by binding in the S1-subsite.

Sreedharan SK, Shah HN, Brocklehurst K.

Biochem Soc Trans. 1994 May;22(2):212S. No abstract available.

PMID:
7958274
12.

Additional evidence for the cysteine proteinase nature of gingivain the extracellular proteinase of Porphyromonas gingivalis.

Sreedharan SK, Patel H, Smith S, Gharbia SE, Shah HN, Brocklehurst K.

Biochem Soc Trans. 1993 May;21(2):218S. No abstract available. Erratum in: Biochem Soc Trans 1993 Nov;21(4):following 1201.

PMID:
8395418
13.

New substrate-derived thiol-specific time-dependent inhibitors for the characterisation of the coupling of binding site interactions with catalytic site chemistry in the cysteine proteinases.

Mellor GW, Patel M, Thomas MP, Kowlessur D, Sreedharan SK, Thomas EW, Brocklehurst K.

Biochem Soc Trans. 1993 May;21(2):215S. No abstract available.

PMID:
8359465

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