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Items: 1 to 50 of 285

1.

Spectrometric evidence for the flavin-1-phenylcyclopropylamine inactivator adduct with monoamine oxidase N.

Mitchell DJ, Nikolic D, Rivera E, Sablin SO, Choi S, van Breemen RB, Singer TP, Silverman RB.

Biochemistry. 2001 May 8;40(18):5447-56.

PMID:
11331009
2.

NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron-sulfur cluster N2 to quinone.

Schuler F, Yano T, Di Bernardo S, Yagi T, Yankovskaya V, Singer TP, Casida JE.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4149-53.

3.

Isolation and characterization of an evolutionary precursor of human monoamine oxidases A and B.

Sablin SO, Yankovskaya V, Bernard S, Cronin CN, Singer TP.

Eur J Biochem. 1998 Apr 1;253(1):270-9.

4.

[Isolation and characterization of an evolutionary precursor of human monoamine oxidases A and B].

Singer TP, Iankovskaia VL, Bernard S, Cronin C, Sablin SO.

Vopr Med Khim. 1997 Nov-Dec;43(6):440-56. Russian.

PMID:
9503562
5.

Inhibitor probes of the quinone binding sites of mammalian complex II and Escherichia coli fumarate reductase.

Yankovskaya V, Sablin SO, Ramsay RR, Singer TP, Ackrell BA, Cecchini G, Miyoshi H.

J Biol Chem. 1996 Aug 30;271(35):21020-4.

6.

Inhibition of NADH oxidation by 1-methyl-4-phenylpyridinium analogs as the basis for the prediction of the inhibitory potency of novel compounds.

Sablin SO, Krueger MJ, Yankovskaya VL, Tkachenko SE, Razdolsky AN, Bachurin SO, Ramsay RR, Singer TP.

J Biochem Toxicol. 1996;11(1):33-43.

PMID:
8806050
7.

Deficiencies of NADH and succinate dehydrogenases in degenerative diseases and myopathies.

Singer TP, Ramsay RR, Ackrell BA.

Biochim Biophys Acta. 1995 May 24;1271(1):211-9. Review.

8.
10.

Dramatic species differences in the susceptibility of monoamine oxidase B to a group of powerful inhibitors.

Krueger MJ, Mazouz F, Ramsay RR, Milcent R, Singer TP.

Biochem Biophys Res Commun. 1995 Jan 17;206(2):556-62.

PMID:
7826372
11.

Redox properties of the flavin cofactor of monoamine oxidases A and B and their relationship to the kinetic mechanism.

Ramsay RR, Sablin SO, Singer TP.

Prog Brain Res. 1995;106:33-9. No abstract available.

PMID:
8584669
12.

The colorful past and bright future of monoamine oxidase research.

Singer TP.

Prog Brain Res. 1995;106:1-22. Review. No abstract available.

PMID:
8584646
13.

The reaction sites of rotenone and ubiquinone with mitochondrial NADH dehydrogenase.

Singer TP, Ramsay RR.

Biochim Biophys Acta. 1994 Aug 30;1187(2):198-202.

PMID:
8075112
15.
16.

Characterization of the inhibitory mechanism of 1-methyl-4-phenylpyridinium and 4-phenylpyridine analogs in inner membrane preparations.

Gluck MR, Krueger MJ, Ramsay RR, Sablin SO, Singer TP, Nicklas WJ.

J Biol Chem. 1994 Feb 4;269(5):3167-74.

17.

Interaction of tetrahydrostilbazoles with monoamine oxidase A and B.

Sablin SO, Krueger MJ, Singer TP, Bachurin SO, Khare AB, Efange SM, Tkachenko SE.

J Med Chem. 1994 Jan 7;37(1):151-7.

PMID:
8289189
18.

The radiochemical assay for monoamine oxidase activity. Problems and pitfalls.

Tipton KF, Singer TP.

Biochem Pharmacol. 1993 Oct 19;46(8):1311-6. Review. No abstract available.

PMID:
8240379
19.
20.

Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds.

Tipton KF, Singer TP.

J Neurochem. 1993 Oct;61(4):1191-206. Review. No abstract available.

PMID:
8376979
21.

An examination of the reliability of the radiochemical assay for monoamine oxidases A and B.

Krueger MJ, Singer TP.

Anal Biochem. 1993 Oct;214(1):116-23.

PMID:
8250212
22.

Comparison of the structures of the quinone-binding sites in beef heart mitochondria.

Tan AK, Ramsay RR, Singer TP, Miyoshi H.

J Biol Chem. 1993 Sep 15;268(26):19328-33.

23.

Oxidation of tetrahydrostilbazole by monoamine oxidase A demonstrates the effect of alternate pathways in the kinetic mechanism.

Ramsay RR, Sablin SO, Bachurin SO, Singer TP.

Biochemistry. 1993 Sep 7;32(35):9025-30.

PMID:
8369275
24.
25.
26.

Biochemical mechanisms underlying MPTP-induced and idiopathic parkinsonism. New vistas.

Singer TP, Ramsay RR, Sonsalla PK, Nicklas WJ, Heikkila RE.

Adv Neurol. 1993;60:300-5. Review. No abstract available.

PMID:
8380523
27.
28.
29.

Differences in substrate specificities of monoamine oxidase A from human liver and placenta.

Tan AK, Weyler W, Salach JI, Singer TP.

Biochem Biophys Res Commun. 1991 Dec 31;181(3):1084-8.

PMID:
1764060
30.

Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase.

Ramsay RR, Krueger MJ, Youngster SK, Gluck MR, Casida JE, Singer TP.

J Neurochem. 1991 Apr;56(4):1184-90.

PMID:
2002336
31.

The kinetic mechanisms of monoamine oxidases A and B.

Ramsay RR, Singer TP.

Biochem Soc Trans. 1991 Feb;19(1):219-23. No abstract available.

PMID:
2037155
32.

The interaction of monoamine oxidases with tertiary amines.

Singer TP, Ramsay RR.

Biochem Soc Trans. 1991 Feb;19(1):211-5. Review. No abstract available.

PMID:
2037153
34.

A new class of powerful inhibitors of monamine oxidase A.

Jin YZ, Ramsay RR, Youngster SK, Singer TP.

Biochem Biophys Res Commun. 1990 Nov 15;172(3):1338-41.

PMID:
2244915
35.

Mechanism of the neurotoxicity of MPTP. An update.

Singer TP, Ramsay RR.

FEBS Lett. 1990 Nov 12;274(1-2):1-8. Review.

36.
37.

Mechanism-based inactivation of monoamine oxidases A and B by tetrahydropyridines and dihydropyridines.

Krueger MJ, McKeown K, Ramsay RR, Youngster SK, Singer TP.

Biochem J. 1990 May 15;268(1):219-24.

38.
39.

Structural dependence of the inhibition of mitochondrial respiration and of NADH oxidase by 1-methyl-4-phenylpyridinium (MPP+) analogs and their energized accumulation by mitochondria.

Ramsay RR, Youngster SK, Nicklas WJ, McKeown KA, Jin YZ, Heikkila RE, Singer TP.

Proc Natl Acad Sci U S A. 1989 Dec;86(23):9168-72.

40.

Enhancement by tetraphenylboron of the interaction of the 1-methyl-4-phenylpyridinium ion (MPP+) with mitochondria.

Ramsay RR, Mehlhorn RJ, Singer TP.

Biochem Biophys Res Commun. 1989 Mar 31;159(3):983-90.

PMID:
2784681
41.

Studies on semirigid tricyclic analogues of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Booth RG, Trevor A, Singer TP, Castagnoli N Jr.

J Med Chem. 1989 Feb;32(2):473-7.

PMID:
2783613
42.

Importance of monoamine oxidase A in the bioactivation of neurotoxic analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Heikkila RE, Kindt MV, Sonsalla PK, Giovanni A, Youngster SK, McKeown KA, Singer TP.

Proc Natl Acad Sci U S A. 1988 Aug;85(16):6172-6.

43.
44.

Mechanism of the neurotoxicity of 1-methyl-4-phenylpyridinium (MPP+), the toxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

Singer TP, Ramsay RR, McKeown K, Trevor A, Castagnoli NE Jr.

Toxicology. 1988 Apr;49(1):17-23. Review.

PMID:
3287690
45.
46.

Inhibition of NADH oxidation by pyridine derivatives.

Ramsay RR, McKeown KA, Johnson EA, Booth RG, Singer TP.

Biochem Biophys Res Commun. 1987 Jul 15;146(1):53-60.

PMID:
2886124
47.

Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Singer TP, Castagnoli N Jr, Ramsay RR, Trevor AJ.

J Neurochem. 1987 Jul;49(1):1-8. No abstract available.

PMID:
3495634
48.
49.
50.

Bioactivation of MPTP: reactive metabolites and possible biochemical sequelae.

Trevor AJ, Castagnoli N Jr, Caldera P, Ramsay RR, Singer TP.

Life Sci. 1987 Feb 23;40(8):713-9.

PMID:
3492651

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