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Items: 41

1.

Diastereo- and enantioselective preparation of cyclopropanol derivatives.

Simaan M, Marek I.

Beilstein J Org Chem. 2019 Mar 21;15:752-760. doi: 10.3762/bjoc.15.71. eCollection 2019.

2.

Pd-Catalyzed Selective Remote Ring Opening of Polysubstituted Cyclopropanols.

Singh S, Simaan M, Marek I.

Chemistry. 2018 Jun 18;24(34):8553-8557. doi: 10.1002/chem.201802016. Epub 2018 May 22.

PMID:
29694690
3.

Asymmetric Catalytic Preparation of Polysubstituted Cyclopropanol and Cyclopropylamine Derivatives.

Simaan M, Marek I.

Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1543-1546. doi: 10.1002/anie.201710707. Epub 2018 Jan 10.

PMID:
29320599
4.
5.

Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling.

House CD, Wang BD, Ceniccola K, Williams R, Simaan M, Olender J, Patel V, Baptista-Hon DT, Annunziata CM, Gutkind JS, Hales TG, Lee NH.

Sci Rep. 2015 Jun 22;5:11541. doi: 10.1038/srep11541.

6.

Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis.

Iglesias-Bartolome R, Torres D, Marone R, Feng X, Martin D, Simaan M, Chen M, Weinstein LS, Taylor SS, Molinolo AA, Gutkind JS.

Nat Cell Biol. 2015 Jun;17(6):793-803. doi: 10.1038/ncb3164. Epub 2015 May 11.

7.

RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock.

Mikelis CM, Simaan M, Ando K, Fukuhara S, Sakurai A, Amornphimoltham P, Masedunskas A, Weigert R, Chavakis T, Adams RH, Offermanns S, Mochizuki N, Zheng Y, Gutkind JS.

Nat Commun. 2015 Apr 10;6:6725. doi: 10.1038/ncomms7725.

8.

Cyclopropene derivatives as precursors to enantioenriched cyclopropanols and n-butenals possessing quaternary carbon stereocenters.

Simaan M, Delaye PO, Shi M, Marek I.

Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12345-8. doi: 10.1002/anie.201412440. Epub 2015 Feb 16.

PMID:
25689601
9.

Differential regulation of endosomal GPCR/β-arrestin complexes and trafficking by MAPK.

Khoury E, Nikolajev L, Simaan M, Namkung Y, Laporte SA.

J Biol Chem. 2014 Aug 22;289(34):23302-17. doi: 10.1074/jbc.M114.568147. Epub 2014 Jul 11.

10.

Somatic mutation of GRIN2A in malignant melanoma results in loss of tumor suppressor activity via aberrant NMDAR complex formation.

Prickett TD, Zerlanko BJ, Hill VK, Gartner JJ, Qutob N, Jiang J, Simaan M, Wunderlich J, Gutkind JS, Rosenberg SA, Samuels Y.

J Invest Dermatol. 2014 Sep;134(9):2390-2398. doi: 10.1038/jid.2014.190. Epub 2014 Apr 16.

11.

Modulable and highly diastereoselective carbometalations of cyclopropenes.

Didier D, Delaye PO, Simaan M, Island B, Eppe G, Eijsberg H, Kleiner A, Knochel P, Marek I.

Chemistry. 2014 Jan 20;20(4):1038-48. doi: 10.1002/chem.201303569. Epub 2013 Dec 12.

PMID:
24338953
12.

An engineering analysis of the aortic valve dynamics in patients with rotary Left Ventricular Assist Devices.

Faragallah G, Simaan MA.

J Healthc Eng. 2013;4(3):307-28. doi: 10.1260/2040-2295.4.3.307.

13.

PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation.

Mikelis CM, Palmby TR, Simaan M, Li W, Szabo R, Lyons R, Martin D, Yagi H, Fukuhara S, Chikumi H, Galisteo R, Mukouyama YS, Bugge TH, Gutkind JS.

J Biol Chem. 2013 Apr 26;288(17):12232-43. doi: 10.1074/jbc.M112.428599. Epub 2013 Mar 6.

14.

Cross-desensitization and cointernalization of H1 and H2 histamine receptors reveal new insights into histamine signal integration.

Alonso N, Fernandez N, Notcovich C, Monczor F, Simaan M, Baldi A, Gutkind JS, Davio C, Shayo C.

Mol Pharmacol. 2013 May;83(5):1087-98. doi: 10.1124/mol.112.083394. Epub 2013 Mar 5.

15.

A suction detection system for rotary blood pumps based on the Lagrangian support vector machine algorithm.

Wang Y, Simaan MA.

IEEE J Biomed Health Inform. 2013 May;17(3):654-63. doi: 10.1109/TITB.2012.2228877. Epub 2012 Nov 21.

PMID:
23192602
16.

Detection of ventricular suction in an implantable rotary blood pump using support vector machines.

Wang Y, Faragallah G, Divo E, Simaan MA.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:3318-21. doi: 10.1109/IEMBS.2011.6090900.

PMID:
22255049
17.

The aortic valve dynamics role in the recovery treatments of patients with left ventricular assist devices.

Faragallah G, Wang Y, Divo E, Simaan M.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:1339-42. doi: 10.1109/IEMBS.2011.6090315.

PMID:
22254564
18.

A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells.

Yagi H, Tan W, Dillenburg-Pilla P, Armando S, Amornphimoltham P, Simaan M, Weigert R, Molinolo AA, Bouvier M, Gutkind JS.

Sci Signal. 2011 Sep 20;4(191):ra60. doi: 10.1126/scisignal.2002221.

19.

Study of G protein-coupled receptor/β-arrestin interactions within endosomes using FRAP.

Aguila B, Simaan M, Laporte SA.

Methods Mol Biol. 2011;756:371-80. doi: 10.1007/978-1-61779-160-4_23.

PMID:
21870240
20.

Role of ßarrestins in bradykinin B2 receptor-mediated signalling.

Zimmerman B, Simaan M, Akoume MY, Houri N, Chevallier S, Séguéla P, Laporte SA.

Cell Signal. 2011 Apr;23(4):648-59. doi: 10.1016/j.cellsig.2010.11.016. Epub 2010 Dec 8.

PMID:
21145390
21.

A method for subsample fetal heart rate estimation under noisy conditions.

Sahin I, Yilmazer N, Simaan MA.

IEEE Trans Biomed Eng. 2010 Apr;57(4):875-83. doi: 10.1109/TBME.2009.2036597. Epub 2009 Nov 20.

PMID:
19932991
22.

C5a- and ASP-mediated C5L2 activation, endocytosis and recycling are lost in S323I-C5L2 mutation.

Cui W, Simaan M, Laporte S, Lodge R, Cianflone K.

Mol Immunol. 2009 Sep;46(15):3086-98. doi: 10.1016/j.molimm.2009.06.007. Epub 2009 Jul 16.

PMID:
19615750
23.

c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway.

Zimmerman B, Simaan M, Lee MH, Luttrell LM, Laporte SA.

Cell Signal. 2009 Jan;21(1):103-10. doi: 10.1016/j.cellsig.2008.09.013. Epub 2008 Oct 1.

PMID:
18938240
24.

Performance prediction of a percutaneous ventricular assist system using nonlinear circuit analysis techniques.

Yu YC, Simaan MA, Mushi SE, Zorn NV.

IEEE Trans Biomed Eng. 2008 Feb;55(2 Pt 1):419-29. doi: 10.1109/TBME.2007.908092.

PMID:
18269977
25.

A discriminant-analysis-based suction detection system for rotary blood pumps.

Ferreira A, Chen S, Simaan MA, Boston JR, Antaki JF.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:5382-5.

PMID:
17946698
26.

Inferring the lifetime of endosomal protein complexes by fluorescence recovery after photobleaching.

Gousseva V, Simaan M, Laporte SA, Swain PS.

Biophys J. 2008 Jan 15;94(2):679-87. Epub 2007 Sep 7.

27.

Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex.

Fessart D, Simaan M, Zimmerman B, Comeau J, Hamdan FF, Wiseman PW, Bouvier M, Laporte SA.

J Cell Sci. 2007 May 15;120(Pt 10):1723-32. Epub 2007 Apr 24.

28.

Towards the development of a pediatric ventricular assist device.

Borovetz HS, Badylak S, Boston JR, Johnson C, Kormos R, Kameneva MV, Simaan M, Snyder TA, Tsukui H, Wagner WR, Woolley J, Antaki J, Diao C, Vandenberghe S, Keller B, Morell V, Wearden P, Webber S, Gardiner J, Li CM, Paden D, Paden B, Snyder S, Wu J, Bearnson G, Hawkins JA, Jacobs G, Kirk J, Khanwilkar P, Kouretas PC, Long J, Shaddy RE.

Cell Transplant. 2006;15 Suppl 1:S69-74. Review.

PMID:
16826798
29.

The PediaFlow pediatric ventricular assist device.

Wearden PD, Morell VO, Keller BB, Webber SA, Borovetz HS, Badylak SF, Boston JR, Kormos RL, Kameneva MV, Simaan M, Snyder TA, Tsukui H, Wagner WR, Antaki JF, Diao C, Vandenberghe S, Gardiner J, Li CM, Noh D, Paden D, Paden B, Wu J, Bearnson GB, Jacobs G, Kirk J, Khanwilkar P, Long JW, Miles S, Hawkins JA, Kouretas PC, Shaddy RE.

Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2006:92-8. Review.

PMID:
16638553
30.

In vitro evaluation of multiobjective hemodynamic control of a heart-assist pump.

Gwak KW, Ricci M, Snyder S, Paden BE, Boston JR, Simaan MA, Antaki JF.

ASAIO J. 2005 Jul-Aug;51(4):329-35.

PMID:
16156294
31.

Dissociation of beta-arrestin from internalized bradykinin B2 receptor is necessary for receptor recycling and resensitization.

Simaan M, Bédard-Goulet S, Fessart D, Gratton JP, Laporte SA.

Cell Signal. 2005 Sep;17(9):1074-83. Epub 2005 Jan 18.

PMID:
15993749
32.
33.

Involvement of a cytoplasmic-tail serine cluster in urotensin II receptor internalization.

Proulx CD, Simaan M, Escher E, Laporte SA, Guillemette G, Leduc R.

Biochem J. 2005 Jan 1;385(Pt 1):115-23.

34.

Calcium channels contribute to the decrease in blood pressure of pregnant rats.

Simaan M, Cadorette C, Poterek M, St-Louis J, Brochu M.

Am J Physiol Heart Circ Physiol. 2002 Feb;282(2):H665-71.

35.

Minimally invasive estimation of systemic vascular parameters.

Yu YC, Boston JR, Simaan MA, Antaki JF.

Ann Biomed Eng. 2001;29(7):595-606.

PMID:
11501624
36.

Pressure-volume relationship of a pulsatile blood pump for ventricular assist device development.

Yu YC, Boston JR, Simaan MA, Miller PJ, Antaki JF.

ASAIO J. 2001 May-Jun;47(3):293-301.

PMID:
11374776
37.

Functional alteration of dihydropyridine-sensitive Ca(2+) channels in the adrenal glomerulosa of pregnant rats.

Simaan M, Picard S, St-Louis J, Brochu M.

Am J Physiol Endocrinol Metab. 2000 May;278(5):E925-32.

38.

The use of confocal microscopy in the investigation of cell structure and function in the heart, vascular endothelium and smooth muscle cells.

Bkaily G, Pothier P, D'Orléans-Juste P, Simaan M, Jacques D, Jaalouk D, Belzile F, Hassan G, Boutin C, Haddad G, Neugebauer W.

Mol Cell Biochem. 1997 Jul;172(1-2):171-94.

PMID:
9278244
39.

Bradykinin activates R-, T-, and L-type Ca2+ channels and induces a sustained increase of nuclear Ca2+ in aortic vascular smooth muscle cells.

Bkaily G, Jaalouk D, Jacques D, Economos D, Hassan G, Simaan M, Regoli D, Pothier P.

Can J Physiol Pharmacol. 1997 Jun;75(6):652-60.

PMID:
9276144
40.

Modulation of cytosolic and nuclear Ca2+ and Na+ transport by taurine in heart cells.

Bkaily G, Jaalouk D, Haddad G, Gros-Louis N, Simaan M, Naik R, Pothier P.

Mol Cell Biochem. 1997 May;170(1-2):1-8.

PMID:
9144312
41.

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